IBMFS - Thrombocytopenia Absent Radii thrombocytopenia absent Radii (TAR). TAR patients are missing one of the two bonesfrom each lower arm. The missing bone is called the radius, and it runs from http://www.marrowfailure.cancer.gov/TAR.html
Extractions: Other Bone Marrow Failure Syndromes TAR patients are missing one of the two bones from each lower arm. The missing bone is called the radius, and it runs from the elbow to the wrist on the side of the thumb. The thumbs are not missing, as they are in some of the other bone marrow failure disorders (see Fanconi's anemia, Diamond-Blackfan anemia). Bruising is due to decreased production of platelets (the cells which help the blood to clot) by the bone marrow and is usually apparent at birth. The gene for TAR has not been identified. Males and females are affected equally. What are the major findings on physical examination? The radius bone is missing from both lower arms The thumbs are present Patients may have small shoulders Patients may have abnormal knees such as bow legs or knock knees
Health - Conditions And Diseases - Genetic Disorders Top Health Conditions and Diseases Genetic Disorders ThrombocytopeniaAbsent radius syndrome See also Health Conditions and http://www.sedirectory.net/Health/Conditions_and_Diseases/Genetic_Disorders/Thro
Extractions: Web Hosting Dir Web Design Dir Search Engine Dir Hardware Info ... Resources Search: Top Health Conditions and Diseases Genetic Disorders ... Thrombocytopenia Absent Radius Syndrome See also: Health: Conditions and Diseases: Rare Disorders NORD: Thrombocytopenia Absent Radius Syndrome - Offers the synonyms, a general discussion and further resources. Pediatric Database - A definition of TAR syndrome, the epidemiology, pathogenesis, clinical features, investigations and management. TAR Syndrome - A personal page about this disorder including links to information. TAR Syndrome Support Group - For families of children born with this rare disorder.
Extractions: Gimenei Health Conditions and Diseases Genetic Disorders Thrombocytopenia Absent Radius Syndrome Electronics: Delphi SA10000 XM SKYFi Radio Receiver - Regular radio got ya down? Loads of commercials, especially those outrageous car dealers, driving you insane? XM is definitely a cure for this! With 100 channels (69 music, 31 talk), and half of the music channels having under 5 minutes of commercials per hour with the other half being commercial-free, there's always plenty to listen to! Lots of variety - from smooth jazz to world pop music, from classical to heavy metal, XM just about covers the musical map. And with news and talk from leading networks like Fox News, CNN, the BBC, E! Entertainment, and many more, you'll never be out-of-the-loop (unless you can't pull yourself away from the music!)
TAR Syndrome Shelton SD, Paulyson K, Kay HH. Prenatal diagnosis of thrombocytopenia absentradius syndrome and vaginal delivery. Prenat Diagn, 1999; 195457. http://ams.cu.edu.tr/July2000Vol9No2/tar.htm
Extractions: Two New Cases of Thrombocytopenia-Absent Radii (TAR) Syndrome* Ercan Kýrými, MD, Nejat Narlý, MD, Mehmet Satar, MD. Thrombocytopenia-absent radii syndrome is characterized by the neonatal onset thrombocytopenia and bilateral absence or hypoplasia of the radii with normal or poorly formed hands and thumbs. In this paper, two unrelated female infants affected by thrombocytopenia-absent radii syndrome are described. At birth, bilateral micromelia of upper limbs, short and radially curved forearms and hypoplastic arms were observed in infants. A severe thrombocytopenia confirmed the clinical diagnosis of thrombocytopenia-absent radii syndrome. One of them died on 19 th day at home with hemorrhagic complications because she was discharged by her family. Other patient supported with thrombocyte suspensions is now eight months old and is still being followed closely at our outpatient department. As a result, two patients with thrombocytopenia-absent radii syndrome which are seen rarely discussed with physical, laboratory and follow specifications. Ann Med Sci 2000;9:78-81 Key words: Thrombocytopenia-absent radii syndrome.
THROMBOCYTOPENIA 60% of thrombocytopenia is classified as idiopathic, but recent ThrombocytopenicAbsentRadius syndrome (TAR); Fanconi anemia- aplastic anemia with associated http://pedclerk.bsd.uchicago.edu/thrombocytopenia.html
Extractions: THROMBOCYTOPENIA th day. 60% of thrombocytopenia is classified as idiopathic, but recent evidence suggests that the underlying cause is related to impaired production of megakaryocytes and platelets secondary to hypoxia. Pathophysiology: Maternal Disorders Drugs- heparin, hydralazine, thiazide diuretics TORCH infections HELLP syndrome Immunologic disorders In mom- ITP, SLE In fetus- Neonatal Alloimmune Thrombocytopenic Purpura (NATP), caused by anti-HPA-1a antibodies from mom. Infants are at risk for intracranial hemorrhage with vaginal delivery. Placental Disorders Chorioangioma Vascular thrombi Placental abruption Neonatal Disorders Decreased platelet production- Normal platelet size with a decreased number of megakaryocytes Thrombocytopenic-Absent Radius syndrome (TAR) Fanconi anemia- aplastic anemia with associated congenital anomalies Congenital leukemia Trisomy 13/18/21 Increased platelet destruction- Increased platelet size with normal or increased number of megakaryocytes Bacterial/candida sepsis TORCH infection DIC Birth asphyxia Necrotizing enterocolitis Clinical Symptoms: The most important part of the physical exam is to distinguish the sick (septic) neonate from the healthy one. Look for petechiae or the presence of mucosal bleeding
