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Tangier Disease: more detail

Tangier disease: An entry from Thomson Gale's <i>Gale Encyclopedia of Genetic Disorders, 2nd ed.</i> by Lisa, MS, CGC Andres, 2005
Tangier Disease - A Bibliography and Dictionary for Physicians, Patients, and Genome Researchers by Philip M. Parker, 2007-07-19
Tangier Disease
Tonsils and apolipoproteins;: Lessons about plasma lipoproteins derived from Tangier disease and other mutants (JimeÌnez DiÌaz memorial lecture) by Donald S Fredrickson, 1976

lists with details

MeSH-D Terms Associated To MeSH-C Term Tangier Disease
MeSHD terms associated to MeSH-C term tangier disease, G2D Home. The number indicates the strength of the association of the corresponding
http://www.bork.embl-heidelberg.de/g2d/c2d.pl?Tangier_Disease:unknown
References For Hypoalphalipoproteinemia, Primary With The MeSH
References for Hypoalphalipoproteinemia, primary with the MeSH term tangier disease, G2D Home. PMID and date. Follow the link to
http://www.bork.embl-heidelberg.de/g2d/exam_mesh_disease.pl?Tangier_Disease:U568
Tangier Disease HIGH DENSITY LIPOPROTEIN DEFICIENCY DUE TO DEFECTIVE METABOLISM
1982 November; 70 (5) 934 945 tangier disease. HIGH DENSITY LIPOPROTEIN DEFICIENCY DUE TO DEFECTIVE METABOLISM OF AN ABNORMAL APOLIPOPROTEIN AI (APOAI TANGIER
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=370306
Studies On The Protein Defect In Tangier Disease ISOLATION AND CHARACTERIZATION
J Clin Invest. 1972 October; 51 (10) 2505 2519 Studies on the Protein Defect in tangier disease. ISOLATION AND CHARACTERIZATION
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=332947
Science -- Sign In
This population carries a rare hereditary disorder, called tangier diseaseafter the name of the islandcharacterized by a defect in cholesterol management
http://intl.sciencemag.org/cgi/content/full/285/5429/814

Extractions: You do not have access to this item: Full Text : Gura, CELL BIOLOGY:Gene Linked to Faulty Cholesterol Transport, Science You are on the site via Free Public Access. What content can I view with Free Public Access If you have a personal user name and password, please login below. SCIENCE Online Sign In Options For Viewing This Content User Name Password this computer. Help with Sign In If you don't use cookies, sign in here Join AAAS and subscribe to Science for free full access. Sign Up More Info Register for Free Partial Access including abstracts, summaries and special registered free full text content. Register More Info Pay per Article 24 hours for US $10.00 from your current computer Regain Access to a recent Pay per Article purchase Need More Help? Can't get past this page? Forgotten your user name or password? AAAS Members activate your FREE Subscription
Tangier From Linkspider UK Health Directory
photos. tangier disease An explanation of this disease and its name, its causes and treatment. tangier disease by Jackie Newman
http://linkspider.co.uk/Health/ConditionsandDiseases/NutritionandMetabolismDisor

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Atherosclerosis Study Sheet
tangier disease articles What are the symptoms of tangier disease? Where does it come from? What gene is mutated in tangier disease?
http://www.bio.davidson.edu/people/kahales/362HumGen/studysheets/Atherosclerosis

Extractions: Your outline of this paper (as mentioned in the syllabus) should consist mainly of a flow chart of the events that lead to atherosclerosis, including important gene products that contribute at each step. My own flow chart includes about ten steps. Don't get bogged down in all the details- try to flesh out what is important. Fazio et al paper:
CNN - Gene May Increase Risk For Heart Disease - October 22, 1999
How the gene was found. A rare genetic disorder called tangier disease provided the clue to the gene s discovery. Individuals with
http://www.cnn.com/HEALTH/9910/22/genetics.cardio.wmd/

Extractions: By Christine Cosgrove (WebMD) Geneticists have located a gene that may be responsible for increasing the risk of heart disease. The gene, called ABC1, normally helps rid the body of cholesterol by maintaining sufficient levels of "good" cholesterol, also known as high density lipoprotein (HDL). But when mutated, the gene can no longer maintain levels of HDL, the researchers said Thursday at the 49th annual meeting of the American Society of Human Genetics in San Francisco. Michael Hayden, one of the lead researchers and a professor of medical genetics at the University of British Columbia, said the study revealed that people with this genetic defect who have low HDL levels are at just as much risk for heart disease as people with high levels of low density lipoprotein (LDL), commonly called "bad" cholesterol.
FreemanPubs
Decreased cholesterol efflux from fibroblasts of a patient without tangier disease, but with markedly reduced high density lipoprotein cholesterol levels.
http://genetics.mgh.harvard.edu/FreemanWeb/Pubs.html
Faculty Profile - Oram
PUBLICATIONS Francis GA, Knopp RH, and Oram JF Defective removal of cellular cholesterol and phospholipids by apolipoprotein AI in tangier disease.
http://depts.washington.edu/metab/faculty/oram.htm

Extractions: Studies of biochemical mechanisms by which high density lipoprotein (HDL) removes cellular cholesterol and phospholipids. Characterization of cellular pathways involved in cholesterol trafficking and their regulation by lipoproteins, cytokines, and hormones. Identification and characterization of signaling molecules involved in modulating cholesterol trafficking. Identification of genes and gene products involved in HDL-mediated removal of cellular lipids. Studies of the molecular and cellular properties of ABCA1, a membrane transporter that mediates secretion of excess cellular cholesterol. Characterization of the properties of HDL apolipoproteins responsible for cellular interactions that facilitate lipid removal. Studies of the effects of diabetes on the properties and activity of ABCA1 and cellular cholesterol trafficking.
Www.nlm.nih.gov/cgi/mesh/2K/MB_cgi?term=Tangier+Disease
Universität Münster Forschungsbericht 19992000 - Translate this page Gefäßkrankheiten. B7-Identifikation der genetischen Ursache von tangier disease - Erstellung und Analyse eines Contigs für Chromosom 9q31.
http://www.nlm.nih.gov/cgi/mesh/2K/MB_cgi?term=Tangier Disease
Tangier Disease
tangier disease. tangier disease http//www.ncbi.nlm.nih.gov An explanation of this disease and its name, its causes and treatment.
http://www.medlina.com/tangier_disease.htm
Nutritional And Metabolic Diseases
Hartnup disease. About Hartnup disease MedStudents (BR). Hartnup disease Karadaglic and Stojanov - eMedicine. About Wilson s disease - MedStudents (BR).
http://www.mic.ki.se/Diseases/C18.html

Extractions: Diseases and Disorders Links pertaining to Nutritional and Metabolic Diseases Alert! Patients and laypersons looking for guidance among the target sources of this collection of links are strongly advised to review the information retrieved with their professional health care provider. Start Page Contents: Acid-Base Imbalance Acidosis Alkalosis Alkaptonuria ... Wolman Disease Nutritional and Metabolic Diseases FDA Center for - (US) International Union of Nutritional Sciences - (AU) The Nutrition Navigator (rating guide) at Tufts University The USDA Nutrient Database for Standard Reference, rel 13 - (US) NATS - Nutritional Analysis Tool and System About some Diagnostic Tests Used in Evaluation of Malabsorption www.FoodSafety.gov Food Safety including a list of Organisms of concern - N Carolina Coop. Ext. Serv. (US) About Food Irradiation - BFE (DE) Facts about Food Irradiation - IAEA (AT) The British Nutrition Foundation Int'l Food Information Council , including a page on Food Additives , and

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