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Schizencephaly:     more detail

The Official Parent's Sourcebook on Schizencephaly: A Revised and Updated Directory for the Internet Age by ICON Health Publications, 2004-02-13 Schizencephaly: An entry from Thomson Gale's <i>Gale Encyclopedia of Neurological Disorders</i> by Peter, MD Lin, 2005 The Official Parent's Sourcebook On Schizencephaly by Icon Health Publications, 2004

lists with details

1. NINDS Schizencephaly Information Page
   schizencephaly information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS). More about schizencephaly,  
   http://www.ninds.nih.gov/health_and_medical/disorders/schizencephaly.htm
   
   Extractions: Schizencephaly is an extremely rare developmental disorder characterized by abnormal slits, or clefts, in the brain's cerebral hemispheres. Schizencephaly is a form of porencephaly in which there is a cyst or cavity in the cerebral hemispheres. Individuals with clefts in both hemispheres (bilateral clefts) are commonly developmentally delayed and have delayed speech and language skills and corticospinal dysfunction. Individuals with smaller, unilateral clefts (clefts in only one hemisphere) are often paralyzed on one side of the body and may have normal intelligence. Patients with schizencephaly may also have varying degrees of microcephaly (abnormally small head), mental retardation, hemiparesis or quadriparesis (partial or complete paralysis), and reduced muscle tone (hypotonicity). Most patients have seizures. Some may have hydrocephalus.

2. WELCOME TO SCHIZ KIDZ BUDDIES!
   Welcome To SCHIZ KIDZ BUDDIES! This web site is provided for persons with schizencephaly and their parents, families, physicians, therapists and friends. schizencephaly is a rare developmental disorder characterized by abnormal clefts in the Persons with schizencephaly may present with varying degrees of developmental delays  
   http://www.geocities.com/Heartland/Meadows/7384
   
   Extractions: Welcome To SCHIZ KIDZ BUDDIES! This web site is provided for persons with Schizencephaly and their parents, families, physicians, therapists,and friends. Schizencephaly is a rare developmental disorder characterized by abnormal clefts in the brain's cerebral hemispheres. Persons with Schizencephaly may present with varying degrees of developmental delays, seizures, delayed speech and language skill, vision and eating disorders. Many have normal intelligence. They may also have microcephaly (abnormally small head), mental retardation, hemiparesis or quadriparesis (partial or complete paralysis)and reduced muscle tone (hypotonicity). Some may have hydrocephalus. Schizencephaly occurs when there is a failure of the normal migration of neurons from the germinal matrix zone at 1-5 months of gestation. Some theories suggest that possible causes of this are in-utero stroke,early gestational viral infections,and recent Italian research has linked Schizencephaly with a mutated gene called the Homeobox gene EMX-2. If the gene EMX-2 is missing or defective, nerve cell growth and migration will not occur normally and this will lead to the formation of the 'clefts' associated with Schizencephaly. We are approximately 800+ families who communicate with each other through our daily EMAIL LIST. The Email List is the "heart" of Schiz Kidz Buddies.... we ask questions, air frustrations, share about our families and our children with Schizencephaly and in doing so gain invaluable support from others who "have been there".

3. Schizencephaly
   schizencephaly is an extremely rare developmental disorder characterized by abnormal slits, or clefts, in the brain’s cerebral hemispheres. schizencephaly.  
   http://healthlink.mcw.edu/article/921961352.html
   
   Extractions: Subscribe now >> Schizencephaly is an extremely rare developmental disorder characterized by abnormal slits, or clefts, in the brain’s cerebral hemispheres. Schizencephaly is a form of porencephaly in which there is a cyst or cavity in the cerebral hemispheres. Individuals with clefts in both hemispheres (bilateral clefts) are commonly developmentally delayed and have delayed speech and language skills and corticospinal dysfunction. Individuals with smaller, unilateral clefts (clefts in only one hemisphere) are often paralyzed on one side of the body and may have normal intelligence. Patients with schizencephaly may also have varying degrees of microcephaly (abnormally small head), mental retardation, hemiparesis or quadriparesis (partial or complete paralysis), and reduced muscle tone (hypotonicity). Most patients have seizures. Some may have hydrocephalus. Treatment for individuals with schizencephaly generally consists of physical therapy, treatment for seizures, and, in cases that are complicated by hydrocephalus, a shunt (a surgically implanted tube that diverts fluid from one pathway to another).

4. Ae
   Closed Lipped schizencephaly. Findings A closely apposed, gray matter lined cleft extends to the left lateral ventricle from the left frontal cortex. Septum pellucidum is absent. Differential Diagnosis  
   http://www.med.uc.edu/neurorad/webpage/aza.html

5. Schizencephaly
   A description of schizencephaly including treatments and prognosis and further reading.  
   http://www.clevelandclinic.org/health/health-info/docs/1300/1338.asp
   
   Extractions: Schizencephaly is an extremely rare developmental disorder characterized by abnormal slits, or clefts, in the brain's cerebral hemispheres. Schizencephaly is a form of porencephaly in which there is a cyst or cavity in the cerebral hemispheres. Individuals with clefts in both hemispheres (bilateral clefts) are commonly developmentally delayed and have delayed speech and language skills and corticospinal dysfunction. Individuals with smaller, unilateral clefts (clefts in only one hemisphere) are often paralyzed on one side of the body and may have normal intelligence. Patients with schizencephaly may also have varying degrees of microcephaly (abnormally small head), mental retardation, hemiparesis or quadriparesis (partial or complete paralysis), and reduced muscle tone (hypotonicity). Most patients have seizures. Some may have hydrocephalus. Is there any treatment?

6. Virtual Hospital: Radiology Resident Case Of The Week: Schizencephaly
   Radiology Resident Case of the Week April 26, 1996. schizencephaly. Lorenzo Carson, M.D Keywords 1. schizencephaly 2. clefts 3. brain malformations  
   http://www.vh.org/pediatric/provider/radiology/PedRadSecTF/042696
   
   Extractions: The cleft may be narrow or closed (type 1) or wide and open (type 2). It is frequently associated with complete or partial absence of the cavum septum pellucidum in approximately 80-90% of cases. The cleft is usually located near the pre- or postcentral gyri. The clefts can be unilateral or bilateral. Polymicrogyria, microcephaly, and gray matter heterotopia have also been noted. Optic nerve hypoplasia has been noted in 33% of cases, with possibility of blindness. Prognosis is poor, with severe intellectual impairment, spastic tetraplegia and blindness. Miscellaneous:

7. Schizencephaly
   Schiz Kidz Buddies support group for children/persons with schizencephaly and their families and caregivers. Includes daily e-mail loop, birthday club for children (they receive stuffed animals, cards, balloons, etc.  
   http://www.kumc.edu/gec/support/schizenc.html

8. Schizencephaly - Eurorad - Clinical Case 955 - Resident
   teaching files radiology schizencephaly was referred to the hospital with frequent daily seizures consisting of double vision and a rigid feeling in the left arm and left leg. He has had these separated by shallow sulci. schizencephaly (split brain) may represent either failure of mechanism for causing polymicrogyria and schizencephaly is probably very similar, and it  
   http://www.eurorad.org/case.cfm?uid=955

9. NINDS - News And Events
   Health. Sorry! There are no press releases for schizencephaly. Use your browser s Back button to return to your previous activity.  
   http://www.ninds.nih.gov/health_and_medical/news.htm?url=/health_and_medical/dis

10. Pediatric Database
    A definition of schizencephaly, the epidemiology, pathogenesis, clinical features, investigations and management.  
    http://www.icondata.com/health/pedbase/files/SCHIZENC.HTM

11. Index
    Personal account about a daughter having Opitc Nerve Hypoplasia, SeptoOptic Dysplasia and had either a Congenital stroke or has schizencephaly.  
    http://www.lebaronfamily.com
    
    Extractions: After many test he finally decided to do a CT scan. Through that test he discovered that she was missing a piece of her brain the size of a walnut in the right hemisphere. Not being able to tell all he wanted to from this test he decided to do aMRI. With the MRI he diagnosed her as having had a Congenital Stroke while in-utero at about 30-40 days after conception. During the week that she spent at Stanford she received many of the same test and was evaluated by many doctors. Finally, they couldn't find anything new and she was stable that whole week so they let us take her home. At that time it was our understanding that they agreed with the diagnoses of Congenital Stroke, and we were told that we were bringing home a well baby.

12. Schizencephaly
    a CHORUS notecard document about schizencephaly Disclaimer. Feedback. Search. schizencephaly. very rare. funnelshaped cleft in midportion of cerebral hemispheres  
    http://chorus.rad.mcw.edu/doc/00363.html

13. Www.geocities.com/Heartland/Plains/8950/schizencephaly.html
    schizencephaly.com .  
    http://www.geocities.com/Heartland/Plains/8950/schizencephaly.html

14. IRSC - Rare Disorders, Schizencephaly
    The Internet Resources for Special Children (IRSC) Global disABILITY resource is dedicated to communicating information relating to the needs of children with disABILITIES on a global basis  
    http://www.irsc.org:8080/irsc/irscmain.nsf/sub?readform&cat=Rare Disorders&a

15. Schizencephaly.com - News
    Welcome! Welcome to schizencephaly.com! Just popping in. Joined 2004/5/3. From Brisbabe Australia. Posts 1. Re Welcome to schizencephaly.com!  
    http://www.schizencephaly.com/modules/news/article.php?storyid=1

16. Schizencephaly.com
    Dedicated to the family, friends, and caregivers of individuals with schizencephaly. FAQs, forum, and resources.  
    http://www.schizencephaly.com

17. Introduction: Schizencephaly - WrongDiagnosis.com
    Introduction to schizencephaly as a medical condition including symptoms, diagnosis, misdiagnosis, treatment, prevention, and prognosis.  
    http://www.wrongdiagnosis.com/s/schizencephaly/intro.htm

18. Schizencephaly
    Click Here to Read our Forum Disclaimer and Statement of Purpose. This Web Forum is not moderated in any sense. Anyone on the Internet can post articles or reply to previously posted articles, and they may do so anonymously. i have a daughter that was diagnosed with bilateral open lip schizencephaly when she was 6 months old still dont know a whole lot about schizencephaly. there is not a  
    http://neuro-www.mgh.harvard.edu/forum_2/GeneralNeurologyF/10.30.993.23PMschizen
    
    Extractions: This Web Forum is not moderated in any sense. Anyone on the Internet can post articles or reply to previously posted articles, and they may do so anonymously. Therefore, the opinions and statements made in all articles and replies do not represent the official opinions of MGH and MGH Neurology. Neither is MGH or MGH Neurology responsible for the content of any articles or replies. No messages are screened for content. This article submitted by Kimberly on 10/30/99. Hi, My name is Kimberly, i have a daughter that was diagnosed with bilateral open lip schizencephaly when she was 6 months old. She is now almost 2. and i still dont know a whole lot about schizencephaly. there is not a lot of info online on this subject. if anyone has any info they can pass along.that would be much appreciated. thank you very much Kimberly Next Article

19. Symptoms Of Schizencephaly - WrongDiagnosis.com
    Symptoms of schizencephaly including signs, symptoms, incubation period, duration, and correct diagnosis. Symptoms of schizencephaly.  
    http://www.wrongdiagnosis.com/s/schizencephaly/symptoms.htm
    
    Extractions: Feedback List of symptoms of Schizencephaly: The list of symptoms mentioned in various sources for Schizencephaly includes: Symptoms of Schizencephaly: Individuals with clefts in both hemispheres (bilateral clefts) are commonly developmentally delayed and have delayed speech and language skills and corticospinal dysfunction. Individuals with smaller, unilateral clefts (clefts in only one hemisphere) are often paralyzed on one side of the body and may have normal intelligence. Patients with schizencephaly may also have varying degrees of microcephaly (abnormally small head), mental retardation, hemiparesis or quadriparesis (partial or complete paralysis), and reduced muscle tone (hypotonicity). Most patients have seizures. Some may have hydrocephalus.

20. EMedicine - Schizencephaly : Article By Ken R Close, MD
    schizencephaly schizencephaly is an uncommon disorder of neuronal migrational characterized by a cerebrospinal fluid–filled cleft, which is lined by gray  
    http://www.emedicine.com/radio/topic622.htm
    
    Extractions: (advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Radiology Pediatrics Last Updated: April 7, 2004 Rate this Article Email to a Colleague Synonyms and related keywords: cerebrospinal fluid–filled cleft in the brain, abnormal cleft of the brain, type I schizencephaly, type II schizencephaly, open-lip schizencephaly, closed-lip schizencephaly AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Differentials Cat Scan ... Bibliography Author: Ken R Close, MD Scott and White Memorial Hospital and Clinic Coauthor(s): L Gill Naul, MD Scott and White Memorial Hospital and Clinic Editor(s): Charles M Glasier, MD , Professor, Departments of Radiology and Pediatrics, University of Arkansas for Medical Sciences; Chief, Magnetic Resonance Imaging, Vice-Chief, Pediatric Radiology, Arkansas Children's Hospital; Bernard D Coombs, MBChB, PhD , Consulting Staff, Department of Specialist Rehabilitation Services, Hutt Valley District Health Board, New Zealand; Marta Hernanz-Schulman, MD, FAAP

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