PiD Kertesz, A (2003) Pick complex An integrative approach to frontotemporal dementia primary progressive aphasia, corticobasal degeneration, and progressive http://www.biols.susx.ac.uk/home/Julian_Thorpe/ad_PiD.htm
Extractions: Alzheimer's Disease and FTD-Tauopathies: a review with particular reference to Pin1 protein Home About this Site Pin1 protein Alzheimer's Disease ... Our Research Literature: A-K L-Z subject area Search site by subject area ... Feedback Compiled by: Julian Thorpe Pick's Disease (PiD) N.B. This page is in the initial phases of construction, so I suggest you follow the external link below for more on this disease. (external site links in italics See: NINDS Pick's disease Information Page and the 'Institut National de la Sante et de la Recherche Medical' website for more detail on PiD. Type: PiD is a sporadic tauopathy belonging to the frontotemporal dementia (FTD) group of neurodegenerative diseases. Regions affected: neocortex and hippocampus. Tau pathology: Neuronal: Pick bodies of straight and twisted filaments of tau in the neocortex (most numerous in layers 2 and 6) and in the dentate granule neurons of the hippocampus. Glial Other Pathology : frontotemporal lobar and limbic atrophy, spongiosis and gliosis.
Extractions: January/February 2002; pages 18-22 Abstract We have described four patients with slowly progressive aphasia with striatal involvement occurring at different stages in the course of the illness. There were two males and two females, and their ages ranged from 68 to 76 (mean: 72) years. The extrapyramidal signs included tremors, bradykinesia, rigidity, and focal dystonia, and one had weakness resembling stroke. There is a heterogeniety among patients with slowly progressive aphasia and the clinical features correspond to the functional anatomy of the areas involved rather than to the pathology.
Argye Hillis, MD Her clinical research interests include studies of aphasia and hemispatial neglectin patients with acute stroke; primary progressive aphasia; and the http://www.neuro.jhmi.edu/profiles/hillis.html
Extractions: Argye Beth Hillis, MD, MA has been on the faculty of the Department of Neurology since 1999. She is an Associate Professor of Neurology, with a joint faculty appointment in Cognitive Science at Johns Hopkins University School of Arts and Sciences. She has clinical responsibilities in both the Division of Cognitive Neurology and Cerebrovascular Disorders. Prior to medical training and neurology residency, Dr. Hillis trained in the fields of speech-language pathology and cognitive neuropsychology. Her clinical practice specializes in stroke, focal dementias, and other cognitive impairments. Her clinical research interests include studies of: aphasia and hemispatial neglect in patients with acute stroke; primary progressive aphasia; and the cognitive effects of neurosurgical interventions, interventional neuroradiology procedures, and cardiac bypass surgery.
Article, Newsworthy, Feinberg School, Northwestern University Dr. Mesulam described, for example, primary progressive aphasia, an unusual dementiaof unknown cause that is characterized by a relentless loss of language http://lydgate.nums.northwestern.edu/feinbergnews/newsDetail.asp?objectID=207&ty
Entrez PubMed Click here to read Cognition and anatomy in three variants of primaryprogressive aphasia. GornoTempini ML, Dronkers NF, Rankin http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1
Progressive Primary Aphasia progressive primary aphasia. General outline Language disorder Apeculiar disease starting with progressive impairment of verbal http://perso.wanadoo.fr/alzheimer.lille/PPA.html
Extractions: ToD Alzheimer Brain dis eases Research ... BD DS GSS F TD FTDP-17 ... untington Hallenvorden IBM L ewy BD MSA NPiD c PDG Parkinson Pick PPA Prion ... SP PEP SSP ToD Progressive primary aphasia General outline Language disorder - A peculiar disease starting with progressive impairment of verbal skills developing into fronto-temporal dementia after several years.
Extractions: 2003, Vol.9, No.2, pp. 140-155 Jason D. Warren , Jane E. Warren , Nick C. Fox and Elizabeth K. Warrington Institute of Neurology, Dementia Research Group, London, UK University of Newcastle Medical School, Auditory Group, Newcastle-upon-Tyne, UK MRC Clinical Sciences Centre, Cyclotron Unit, Hammersmith Hospital, London, UK
Penn State Faculty Research Expertise Database (FRED) aphasia, PostIctal, aphasia, Post-Traumatic. aphasia, progressive, aphasia,Semantic. aphasia Post-Traumatic aphasias, progressive aphasia. progressive http://fred.hmc.psu.edu/ds/retrieve/fred/meshdescriptor/D001037
Blackwell Synergy - Cookie Absent Case Report. An autopsy case of Alzheimer s disease presenting with primaryprogressive aphasia A clinicopathological and immunohistochemical study. http://www.blackwell-synergy.com/links/doi/10.1046/j.1440-1789.2000.00343.x/full
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Alzheimer's Association Of Orange County http//www.angelsonmyside.com/picks2/picks.html. Websites for primary Progressiveaphasia (PPA) http//www.brain.northwestern.edu. http//www.aphasia.org. http://www.alzoc.org/thedisease/Pickslinks.htm
Medical Expert aphasia Diagnosis. January 2000 Q. My 79year-old mother was diagnosed with primaryprogressive aphasia three years ago. She has been taking Aricept since then. http://www.medinfosource.com/expert/exp3013100d.html
Extractions: Select One Contact CME? Order? Register? Place an Ad? Print Pages? Ask a Colleague? More... AIDS/HIV Allergy Alternative Med. Alzheimer's Arthritis Asthma Blood Disorders Cancer Childhood Illness Chronic Fatigue Common Cold Dementia Dermatology Diabetes Ear/Nose/Throat Exercise Gastrointestinal Geriatrics Headache Heart Disease Hepatitis High Cholest. Medications Men's Health Migraine Nervous Syst. Neurology Nutrition Opthamology Orthopedics Osteoporosis Pediatrics Pregnancy Skin Disorders Sleep Disorders Stroke/TIA Women's Health January 2000 Q. My 79-year-old mother was diagnosed with primary progressive aphasia three years ago. She has been taking Aricept since then. We have seen great degeneration in her ability to reason, comprehend and find a word that seems to be on the tip of her tongue. Is there any other help for her? How much benefit is Aricept for these symptoms? A. Aphasia is a difficulty with speech, either hearing the spoken word (receptive aphasia) or speaking itself. Aphasia can have many causes, from severe mental retardation, stroke, Alzheimer's disease, or (as in your mother's case) there is sometimes no identifiable cause, and the person is diagnosed with primary progressive aphasia. The difficulty is making a definite diagnosis as to the type of aphasia a person has. Since Alzheimer's disease is a frequent cause of aphasia, and since Aricept is frequently helpful in patients with Alzheimer's disease, many patients with primary progressive aphasia will be given Aricept as a trial. So, in other words, the Aricept is used primarily with the hope that it is going to work, rather than with the knowledge that it is effective in primary progressive aphasia.
Extractions: (advertisement) Synonyms, Key Words, and Related Terms: frontotemporal dementia, frontal dementia, nonspecific dementia, Pick's disease, Pick disease, primary progressive aphasia, FTD, PPA Background: Cases of elderly patients with progressive language deterioration have been described since Arnold Pick's landmark case report of 1892. This case study, "On the relationship between aphasia and senile atrophy of the brain," still serves as a frame of reference for apparently focal brain syndromes in diffuse or generalized degenerative diseases of the brain. In 1982, Mesulam reported 6 patients with progressive aphasia, gradually worsening over a number of years, who did not develop a more generalized dementia. Since Mesulam's publication, numerous other cases have been reported. This disorder, which is currently termed primary progressive aphasia (PPA), has gained acceptance as a syndrome. Rarely, cases of isolated right frontal or temporal degeneration have been reported. These patients experience failure to recognize family members (prosopagnosia), failure to remember topographic relationships, and similar disorders. In England, cases of frontal lobe dementia have been described with progressive dysfunction of the frontal lobes. In a series of case reports, Neary and Snowden outlined a syndrome with initial symptoms that were suggestive of psychiatric illness. However, the following frontal lobe behavioral abnormalities appeared over time: disinhibition, impulsivity, impersistence, inertia, loss of social awareness, neglect of personal hygiene, mental rigidity, stereotyped behavior, and utilization behavior (ie, tendency to pick up and manipulate any object in the environment). These descriptions included language abnormalities such as reduced speech output, mutism, echolalia, and perseveration. Recently, the condition described in the North American literature as PPA and that described in the European literature as frontal dementia have been combined under the diagnosis frontotemporal dementia (FTD).
Riferimenti Bibliografici Sezione intestazione vai alla sezione contenuti vai alla sezionenavigazione. Il portale di neuropsicologia clinica un progetto http://www.neuropsy.it/articoli/dir06/06.html
Extractions: Commento finale Paragrafi Neuropsy.it Cos'è Neuropsy.it La Neuropsicologia clinica Contatti Sezioni Formazione Casi clinici Articoli scientifici Test neuropsicologici Patologie Neoplasie Alzheimer Parkinson Trauma cranico ... Depressione Deficit Dislessia Funzioni Intelligenza Gruppo di discussione neuropsy.it , il su yahoo Mailing list Vuoi essere informato sulle novità di neuropsy.it? iscriviti alla nostra mailing list iscriviti Forum I forum di Neuropsy.it, per discutere di intelligenza, depressione, dislessia, alzheimer, trauma cranico. Sezione contetuti Vai alla sezione intestazione vai alla sezione navigazione neuropsy.it articoli ... Afasia progressiva con demenza rapidamente progressiva in una donna di 49 anni Riferimenti bibliografici Apparso in: J Neurol Neurosurg Psychiatry 1999 ; 66 : 238- 243 (February): Conferenza su un caso di clinica patologica