Ovarian Failure (premature) - General Practice Notebook ovarian failure (premature). In one series, it accounted for 36% of cases of primary amenorrhoea, and 29% of cases of secondary amenorrhoea. http://www.gpnotebook.co.uk/cache/-315293685.htm
Extractions: ovarian failure (premature) This is defined as menopause occurring in women prior to the age of 40 years. It is a not uncommon cause of amenorrhoea. In one series, it accounted for 36% of cases of primary amenorrhoea, and 29% of cases of secondary amenorrhoea. Diagnosis requires elevated gonadotrophins - FSH above 40 IU per litre together with raised LH and low oestradiol (less than 100 pmol per litre) on at least two occasions. Ultrasound usually reveals small ovaries, a small uterus and a thin endometrium. Note that reference ranges may vary between laboratories.
WHAT CAUSES AMENORRHEA? Anorexia and Bulimia. The eating disorders anorexia and bulimia may be a primary factor in many cases of FHA. Premature ovarian failure. http://www.ucdmc.ucdavis.edu/ucdhs/health/a-z/101Amenorrhea/doc101causes.html
Extractions: The most common cause of primary amenorrhea is delayed puberty due to some genetic factor that delays physical development. Being short is the most common sign of this, although sometimes a family history of delayed menstruation can indicate this situation. Time usually resolves the problem. Functional hypothalamic amenorrhea (FHA) is the absence of menstruation due to disturbances in the thyroid gland and hypothalamus-pituitary-adrenal (HPA) system. FHA may be due to different factors, most unknown. The hypothalamus and the pituitary gland regulate the reproductive hormones. It triggers the production and release of steroid hormones ( glucocorticoids ), including the primary stress hormone cortisol . The HPA system manages appetite and mood as well. Anorexia and Bulimia. The eating disorders anorexia and bulimia may be a primary factor in many cases of FHA. Both weight loss and changes of appetite may cause hormonal abnormalities. Such changes may be due to a primitive protective biologic mechanism, which was designed to prevent potentially harmful pregnancies during times of famine. Hormonal changes to extreme weight loss and reduced fat stores include low thyroid levels (hypothyroidism) and excessive stress hormone levels (hypercortisolism), which in turn reduce reproductive hormones. Reducing stress hormones, in one study, helped elevate reproductive hormones in women with FHA.
Extractions: Michael J. Heard, M.D. Dr. Heard is a Reproductive Endocrinologist in private practice in Houston, Texas. Board certified in Obstetrics and Gynecology and a Fellow in the American College of Obstetricians and Gynecologists, Dr. Heard maintains a specialized focus on the evaluation and treatment of premature ovarian failure (POF). He is the medical director of the Houston POF Support Group, one of the largest POF support groups in the country. He also interacts with patients with POF all over the United States and around the world through his private practice and the internet. Dr. Heard is a member of the Houston chapter of RESOLVE, the National Fertility Association, and the American Society of Reproductive Medicine. Dr. Heard received his M.D. from Emory University School of Medicine in Atlanta, Georgia. He trained in obstetrics and gynecology at the University of Tennessee in Memphis and went on to serve four years on active duty as an officer in the United States Air Force. Dr. Heard completed a three-year Fellowship in Reproductive Endocrinology and Infertility at Baylor College of Medicine in Houston. He was recently appointed Assistant Clinical Professor at the University of Texas Health Science Center in Houston. The Latest Facts About Premature Ovarian Failure
Entrez PubMed Based on its primary structure, it appears to be novel and has no motifs that OP1 as an antigen may play a role in murine autoimmune premature ovarian failure. http://www.biomedcentral.com/pubmed/10433232
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Amenorrhea The causes of primary amenorrhea are also quite different from secondary and decreased libido along with her amenorrhea may have premature ovarian failure. http://www.advancedfertility.com/amenor.htm
Extractions: Secondary Amenorrhea Lack of menstrual periods in a woman that has had periods previously Background Secondary amenorrhea is the absence of menstrual periods for 6 months in a woman who had previously been regular, or for 12 months in a woman who had irregular periods. This problem is seen in about 1% of women of reproductive age. Primary amenorrhea is when the woman has never had a period in her life. This page will not discuss primary amenorrhea which is rare. The causes of primary amenorrhea are also quite different from secondary amenorrhea. The most common cause of secondary amenorrhea in reproductive age women is pregnancy and this should always be excluded by physical exam and laboratory testing for the pregnancy hormone - HCG. History A good history can reveal the etiologic diagnosis in up to 85% of cases of amenorrhea. A detailed menstrual history should be taken. Any history of galactorrhea (milky discharge from the breasts) is important and indicates the need for a prolactin hormone level to rule out hyperprolactinemia. A woman who has had hot flashes, breast atrophy and decreased libido along with her amenorrhea may have premature ovarian failure.
Extractions: III. Department of Medicine, University of Leipzig, Leipzig, Germany Download the FULL TEXT of this article in Acrobat PDF format. If you have not previously downloaded PDF files we suggest you access our Advice page for further information. European Journal of Endocrinology Return to the Contents List - Vol. 146 Part 1
Blackwell Synergy - Cookie Absent The incidence of premature ovarian failure (POF) in women with epilepsy has not been had POF compared with two of nine women with primary generalized epilepsy http://www.blackwell-synergy.com/links/doi/10.1046/j.1528-1157.2001.13701r.x/abs
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Cancer.gov women undergoing adjuvant or neoadjuvant chemotherapy for primary breast cancer. history, and chemotherapy regimen with ovarian failure (permanent cessation of http://www.cancer.gov/clinicaltrials/view_clinicaltrials.aspx?version=healthprof
Türk Fertilite Dergisi Results Premature ovarian failure is a syndrome characterized by hypoestrogenism, hypergonadism (FSH 40IU/L), primary or secondary amenorrhea in women below http://www.tivak.org.tr/journal/goster.php?id=84
Extractions: Little is known about the causes of Premature Ovarian Failure (POF) in women. This disorder is defined as the loss of ovarian function before the age of forty. It is clinically characterized by secondary amenorrhea and endocrinologically by a hypergonadotropic, hypoestrogenic state. Unfortunately, a definite etiological factor can not be determined for most cases (van Kasteren, 1999). Currently, the condition is divided into two classes: excessive depletion of follicles and follicles that are present but fail to function properly. It is also likely that different classes POF exist due to different causes or varying levels of the agents responsible for this disorder. It is possible that one of the major or contributing causes of POF dysfunction involves the autoimmune reaction against the oocyte and/or other components of the follicle. Such a primary relationship might follow an initial abnormal exposure of zona material to the immune system. Alternatively, in POF or other types of pathology, anti zona pellucida antibodies (aZP) might form as a secondary consequence of disease conditions (Shivers and Dunbar, 1977).
Clinical Guidelines 75, Epithelial ovarian cancer, QRG 75 (174K). Guideline 75 40, Lipids and the primary prevention of coronary 35, Diagnosis and treatment of heart failure due to http://www.sign.ac.uk/guidelines/published/
Extractions: Clinical Guidelines Items marked are available in Acrobat format ( info This list has been categorised by guideline subject. You can also view a list by guideline number Cancer CHD and Stroke Child Health ... Other No. Guideline Title Quick reference guide Full guideline Publication Date Long term follow up care of survivors of childhood cancer
Ivf-infertility.com | Polycystic Ovarian Syndrome (PCOS) Polycystic ovarian syndrome (PCOS), is a primary ovarian condition and is characterized by the risk of destruction of the ovaries leading to ovarian failure. http://www.ivf-infertility.com/infertility/pcos.php
Extractions: Advertising PCOS Polycystic Ovarian Syndrome Polycystic ovarian syndrome (PCOS) accounts for 90% of women with oligomenorrhoea (infrequent periods) and 30% of women with amenorrhoea (absent of periods) and over 70% of women with anovulation. Laparoscopy Laparoscopy allows direct inspection of the ovaries; the ovaries are enlarged and polycystic. However, polycystic ovaries may appear normal at laparoscopy.
Extractions: Ovarian Failure After Adjuvant Chemotherapy Is Associated with Rapid Bone Loss in Women With Early-Stage Breast Cancer, by Charles L. Shapiro, Judith Manola, and Meryl Leboff; Journal of Clinical Oncology, July 15, 2001. Here is the important background information that the authors give us: over the past 30 years, mammographic screening and early detection of nonpalpable breast cancers has increased the number of breast cancer survivors, guidelines from that National Institutes of Health and the National Comprehensive Cancer Network recommend adjuvant chemotherapy (Ed: adjuvant chemotherapy = chemotherapy treatment that is given as an add-on to the primary cancer treatment) for all invasive breast cancer tumors greater than 1 cm, one of the most common side effects of adjuvant chemotherapy is ovarian failure or premature menopause. This premature menopause occurs in 63% to 85% of women treated with cyclophosphamide, methotrexate, and fluorouracil and 50% of women treated with anthracycline, patients over 40, who are closer to their natural menopausal age, develop ovarian failure after a shorter duration of chemotherapy, typically within the first few months
COCHRANE MENSTRUAL DISORDERS AND SUBFERTILITY GROUP Nonsteroidal antiinflammatory drugs for primary dysmenorrhoea (Cochrane Review); induction in women with spontaneous premature ovarian failure (Cochrane Review http://www.mediscope.ch/cochrane-abstracts/g180index.htm
Extractions: Note: 'Protocols' are the introduction, objectives, materials and methods for reviews currently being prepared. Androgens versus placebo or no treatment for idiopathic oligo/asthenospermia (Cochrane Review) Antifibrinolytics for heavy menstrual bleeding (Cochrane Review) Barrier agents for preventing adhesions after surgery for subfertility (Cochrane Review) Bromocriptine for idiopathic oligo/asthenospermia (Cochrane Review) ... Oral oestrogen replacement therapy versus placebo for hot flushes (Cochrane Review) Ovulation induction with urinary follicle stimulating hormone versus human menopausal gonadotropin for clomiphene-resistant polycystic ovary syndrome (This review has been withdrawn by the editorial group. Abstract not available)
Unusual Presentation Of Primary Ovarian Pregnancy ABSTRACT primary ovarian pregnancy is a rare entity, the reported incidence Pregnancy; ovarian failure, Premature/DI; Uterus; Laparotomy; Human; Female; Adult http://medind.nic.in/imvw/imvw3128.html
Menopause climacteric arthritis; ovarian failure; perimenopause; premenopausal menorrhagia. guidance is given on how to obtain freeof-charge primary research results via http://www.icongrouponline.com/health/Menopause_Ph.html
Extractions: E B O O K Electronic File * E-Book version sent via e-mail in 2 business days Electronic File *E-Book version sent via e-mail in 2 business days Pages Price $78.95(USD) ISBN Published Synopsis In March 2001, the National Institutes of Health issued the following warning: "The number of Web sites offering health-related resources grows every day. Many sites provide valuable information, while others may have information that is unreliable or misleading." Furthermore, because of the rapid increase in Internet-based information, many hours can be wasted searching, selecting, and printing. Since only the smallest fraction of information dealing with menopause is indexed in search engines, such as www.google.com or others, a non-systematic approach to Internet research can be not only time consuming, but also incomplete. This book was created for medical professionals, students, and members of the general public who want to conduct medical research using the most advanced tools available and spending the least amount of time doing so. Related Conditions/Synonyms climacteric arthritis; ovarian failure; perimenopause; premenopausal menorrhagia
Extractions: About the POFSG Contact Us Our Mission Our History ... Home Identification of genes associated with Primary Gonadal Failure - Massachusetts General Hospital Cara Penney, a Physician Assistant who works with Dr. Ann Taylor on POF research studies. Currently, they are involved in recruiting for the following two POF studies: They are also asking POF women to provide a small amount of blood in the hopes of better understanding the possible autoimmune involvement in the development of POF. Currently, this blood sample needs to be drawn at Massachusetts General Hospital. A medical history will be obained.This study is funded by the NIH and may have therapeutic implications in the next 5 years. Please call Cara Penney, PA-C at (617) 726-9263 if you are interested or have any questions. Dr. Ann Taylor is a practicing Reproductive Endocrinologist at Massachusetts General Hospital. She is accepting new patients for consultation and appointments can be made at (617) 726-8433.
