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Pernicious Anemia:     more books (94)

The interpretation of reticulocyte responses in pernicious anemia by George Richards Minot, 1934 Pernicious anemia an its relationship to sprue: A preliminary report by Edward Jenner Wood, 1925 Pernicious anemia: A continued study (Second annual Merrimon lecture) by William B Castle, 1967 Studies on red blood cell diameter: II. in pernicious anemia, before and during marked remission, and in myelogenous leukemia by Donald N Medearis, 1927 Probably unique collection of 43 monographs, all on pernicious anemia by G.R. & MURPHY, W.P., et al. MINOT, 1934 Treatment of pernicious anemia with liver extract: Effects upon the production of immature and mature red blood cells (Cancer Commission of Harvard University) by George Richards Minot, 1928 How To Recognize and Treat Pernicious Anemia: Low Vitamin B-12 by Quick Easy Guides, 2008-07-31 A case of hypoplastic anemia, pernicious type, in the course of sprue, with frequency repeated hematological examinations by Bailey K Ashford, 1931 A NEW MICROSCOPIC PRINCIPLE. In Nature Vol. 161, No. 4098. Pages 777-778. Also in this volume are three important medical papers: PRE-ERYTHROCYTIC STAGE IN MAMMALIAN MALARIA PARASITES, PURIFICATION OF ANTI-PERNICIOUS ANEMIA FACTORS FROM LIVER, and CUARE-LIKE ACTION OF POLYETHYLENE BIS-QUARTERNARY AMMONIUM SALTS. by Dennis. Nobel Laureate in Physics. ( H. E. Shortt, E. Lester Smith, and W. D. M. Paton and E. J. Zaimis) GABOR, 1948-01-01 The nature of the material in liver effective in pernicious anemia: II by Edwin Joseph Cohn, 1928 The response of the reticulocytes to liver therapy: Particularly in pernicious anemia (Cancer Commission of Harvard University) by George Richards Minot, 1928 The myelopathy of pernicious anemia: A neuropathological reapprisal (Acta neurologica Scandinavica, v. 44. Supplementum) by Shyam S Pant, 1968 Collected reprints on early uses of liver diet for treatment of pernicious anemia by George Richards Minot, 1926 The importance of the treatment of pernicious anemia on a quantitative basis by George Richards Minot, 1932

lists with details

81. Vitamin B12 -- Anemia / Sleep / Mental Quickness
    This verifies reports from Sweden dating from the 1970s that pernicious anemia, a disease of B12 deficiency, can be controlled with oral B12.  
    http://www.smartbodyz.com/vitamin-B12-text.htm
    
    Extractions: Reprinted by permission from Bill Faloon of The Life Extension Foundation by Terri Mitchell For decades, people have been injecting themselves with vitamin B12 because they thought oral supplements were not adequately absorbed. New research indicates that oral B12 supplements may be as good or better than injections. Those who have low levels of vitamin B12 in the blood have long resorted to injections of this essential B vitamin, an uncomfortable delivery method at best. New evidence suggests that oral B12 works as well as injections, according to a study published in the journal Blood but high doses must be taken. This verifies reports from Sweden dating from the 1970s that pernicious anemia , a disease of B12 deficiency, can be controlled with oral B12. Resolving the debate over oral-versus-injections is very timely, given that vitamin B12 is a homocysteine-lowering factor. Homocysteine has emerged as a strong and independent risk factor for heart disease and stroke, and is also connected to chronic diseases such as

82. Vitamin Syndromes
    Gastrointestinal malabsorption Deficient intrinsic factor production Postgastrectomy; Antibody vs parietal cells 6 pernicious anemia  
    http://www.neuro.wustl.edu/neuromuscular/nother/vitamin.htm

83. Welcome To AJC!
    pernicious anemia. pernicious anemia results from a lack of intrinsic factor in gastric secretions which, in turn, causes inadequate vitamin B12 absorption.  
    http://www.ajc.com/search/healthfd/shared/health/adam/ency/article/000569.html
    
    Extractions: Subscribe ... Register Now It's Free! Log in E-mail preferences Site Index Search: Site Yellow Pages Customer care ajc.com Nation/World Metro ... Personals ajc services Archives Advertise online Advertise in print Obituaries ... Sitemap Print edition Today This week A1 image E-mail News  Sign up for our Ency. home Disease P Pernicious anemia Overview Symptoms Treatment Prevention Alternative names: Addison's anemia; Biermer's anemia; Macrocytic achylic anemia; Congenital pernicious anemia; Juvenile pernicious anemia; Vitamin B12 deficiency (malabsorption) Definition: A form of anemia caused by a lack of intrinsic factor , a substance needed to absorb vitamin B12 (cobalamin) from the gastrointestinal tract. Causes and Risks Intrinsic factor is a binding protein required for the absorption of vitamin B12. Pernicious anemia results from a lack of intrinsic factor in gastric secretions which, in turn, causes inadequate vitamin B12 absorption. Vitamin B12 deficiency is the result. The vitamin B12 deficiency causes a form of anemia specifically referred to as megaloblastic anemia Other causes of pernicious anemia include atrophic gastric mucosa, autoimmunity against gastric parietal cells, and autoimmunity against instrinsic factor.

84. NCI: Pernicious Anemia
    NCI Dictionary from PDQ®. Numbers A B C D E F G H I J K L M N O P Q R S T U V W X Y Z pernicious anemia. (perNISH-us a-NEE-mee-a)  
    http://www.jamesline.com/patientsandpublic/cancertypes/glossary/index.cfm?action

85. Nat'l Academies Discovery Engine
    Currently using pernicious anemia as the search focus. high intake of folate has been said to delay the diagnosis of pernicious anemia.  
    http://lab.nap.edu/nap-cgi/discov9.cgi?term=pernicious anemia&restric=

86. Nat'l Academies Discovery Engine
    Currently using pernicious anemia as the search focus. Try this search on the older NAP title search Please comment on the Discovery Engine.  
    http://lab.nap.edu/nap-cgi/discov9.cgi?term=pernicious anemia&restric=NAP

87. Introducing Vita-Man B12
    The classic B12 deficiency diseases is called pernicious anemia. Before the cause of pernicious anemia was understood, this disease was always fatal.  
    http://www.vita-men.com/xnoplug/xcardB12/xB12frnt.htm
    
    Extractions: Water soluble Vita-Man sm B is essential for growth, for the formation of mature red blood cells, and for the normal functioning of the nervous system. The classic B deficiency diseases is called pernicious anemia. If the supply of Vitamin B is inadequate, people develop pernicious anemia because their bodies can't form red blood cells properly. The word "pernicious" means "causing great harm" a good description of this disease. Before the cause of pernicious anemia was understood, this disease was always fatal. The spinal cord, brain, and other parts of the nervous system need Vita-Man B in order to function properly. Without him, serious neurologic symptoms may develop. Too much homocysteine in the bloodstream has been associated with an increase in the risk of heart disease. Vita-Man B and his two teammates (Vita-Man B and Vita-Woman Folic Acid) are necessary for the reactions that transform homocysteine into other substances and prevent it from building up to potentially harmful levels.

88. Pernicious Anemia
    pernicious anemia. Slide 29 of 33.  
    http://meds.queensu.ca/medicine/deptmed/hemonc/macro/slide29.html

89. Vitamin B12 Deficiency Information From EVitamins
    Vitamin B12 Deficiency. Also indexed as pernicious anemia. nervous system. The result is pernicious anemia (PA). In the classical  
    http://www.evitamins.com/healthnotes/healthnotes.asp?ContentID=1287007

90. Vitamins & Anemia
    Its isolation from liver brought to a successful conclusion more than 20 years of investigation aimed at finding the cause of pernicious anemia.  
    http://www.clevelandclinic.org/myeloma/anemiaANDvitamins.htm
    
    Extractions: General Concept The maintenance of normal red cell mass and the synthesis of hemoglobin are normally adjusted to take care of the physiological loss of the blood elements. Anemia results when there is excessive loss or diminished replacement of red cells. Most anemia's are deficiency diseases resulting from inadequate tissue concentrations of iron, vitamin B12, or folic acid. Correction of the deficiency is highly successful provided an accurate diagnosis is made. Erythropoietin is a useful stimulator of bone marrow in certain diseases. Iron Iron is contained in the body in various forms, principally as hemoglobin. Normal blood contains about 15 g of hemoglobin/100 ml, and each gram of hemoglobin contains 3.4 mg of iron. It may be calculated then that the total normal blood volume contains about 2.6 g of iron. In addition to hemoglobin, iron is contained in ferritin, the storage form for iron in the tissues, and in the serum attached to the carrier substance, the globulin transferrin. Minute quantities are also present in the cytochrome enzymes and myoglobin of muscle. Quantitatively, hemoglobin and ferritin contain the bulk of the iron in the body, amounting to a total of about 4 to 5 g. Under normal circumstances red cells are broken down at a steady rate, their lifespan being on the order of 120 days. Most of the iron released from the breakdown of hemoglobin is reutilized. As a consequence, the daily iron requirement in a normal adult is quite low, about 1 mg. Growth, menstruation, and pregnancy increase the iron requirement.

91. The Anemia File: Ground-breaking New Research
    pernicious anemia—current research on the treatment and prognosis of pernicious anemia, as well as the complications associated with this form of anemia.  
    http://www.lifestages.com/health/anemia.html
    
    Extractions: W Anemia File . Learn about late-breaking research from recognized experts at blood centers and departments of internal medicine worldwide. Compiled from the National Library of Medicine database at the National Institutes of Health, the Anemia File Anemia File informs you about studies at such renowned institutions as Mount Sinai Medical Center in New York, the Blood and Marrow Transplant Program at the University of Minnesota, and the Mayo Clinic. The Anemia File brings you the inside medical story on: Pernicious Anemia Aplastic Anemia Iron Deficiency Anemia Cobalamine Deficiency Hormone Therapy for Anemia Transplantation Techniques Hemolytic Anemia Diamond-Blackfan Anemia Fanconi Anemia General Studies in Anemia Care Access to Free Full-Text Articles from Postgraduate Medicine, the British Medical Journal, and the New England Journal of Medicine

92. Nutrimed Labs: PERNICIOUS ANEMIA
    Condition pernicious anemia. SUGGESTED NUTRITION PHYSIOLOGICAL CONSIDERATIONS pernicious anemia is basically a nutritional deficiency disease.  
    http://www.nutrimed.com/ANEMIAP.HTM
    
    Extractions: PATHOLOGICAL CONSIDERATIONS: A chronic, macrocytic anemia characterized by achlorhydria, gastro-intestinal disturbances, and neurologic syndromes. It occurs most often in Caucasians after age 50. The fundamental defect is a permanent deficiency of the intrinsic factor normally present in gastric juice. In addition to atrophy of gastric mucosa and changes in bone marrow common to all megaloblastic anemias, there is often specific neurologisc changes. Subacute combined degeneration of the spinal cord is a common finding. Degeneration may also occur in peripheral nerves, nerve plexuses of the gastro-intestinal tract, and subcortical areas in the motor region of the brain. PHYSIOLOGICAL CONSIDERATIONS: Pernicious anemia is basically a nutritional deficiency disease. Characteristic blood abnormalities can be corrected by use of folic acid. However, if there is an accompanying deficiency of vitamin B-12, an irreversible degeneration of the spinal cord may take place. The intrinsic factor normally produced by stomach mucosa is necessary in order that B-12 may be absorbed and utilized. In pernicious anemia, the stomach has become unable to produce either the intrinsic factor or hydrochloric acid. Vitamin B-6 and vitamin C increase absorption of vitamin B-12. Adequate protein is also needed as vitamin B-12 is almost always associated with animal proteins such as liver, kidney, muscle meats, etc.

93. Pernicious (Anemia) Articles, Support Groups, And Resources
    pernicious (anemia) articles, support groups, and resources for patients from Med Help International (www.medhelp.org). pernicious (anemia).  
    http://www.medhelp.org/HealthTopics/Pernicious.html

94. UAB Health System | Megaloblastic (Pernicious) Anemia
    Megaloblastic (pernicious) anemia. What is anemia? Always consult your physician for a diagnosis. What is megaloblastic (pernicious) anemia?  
    http://www.health.uab.edu/show.asp?durki=15481

95. Hematology & Blood Disorders - Megaloblastic (Pernicious) Anemia
    Megaloblastic (pernicious) anemia. What is megaloblastic (pernicious) anemia? Megaloblastic What causes megaloblastic (pernicious) anemia? Megaloblastic  
    http://www.med.utah.edu/healthinfo/adult/Hemat/aneper.htm
    
    Extractions: What is anemia? Anemia is a common blood disorder, which is caused when there is a drop in hemoglobin or hematocrit in the blood. Anemia may be a symptom of another disease. The following are the most common symptoms of anemia. However, each individual may experience symptoms differently. Symptoms may include: abnormal paleness or lack of color of the skin increased heart rate (tachycardia) breathlessness, or difficulty catching a breath (dyspnea) lack of energy, or tiring easily (fatigue) dizziness, or vertigo, especially when standing headache irritability irregular menstruation cycles absent or delayed menstruation (amenorrhea) sore or swollen tongue (glossitis) jaundice, or yellowing of skin, eyes, and mouth

96. Megaloblastic (Pernicious) Anemia
    Detailed information on megaloblastic (pernicious) anemia, including causes, symptoms, diagnosis, and treatment. Megaloblastic (pernicious) anemia.  
    http://www.healthsystem.virginia.edu/uvahealth/peds_hematology/megalob.cfm
    
    Extractions: @import url(/assets/UVAHealth/ssi/css/greystone_advance.css); Adolescent Medicine Allergy/Asthma/Immunology Blood Disorders Burns Cancer Common Injuries/Poison Tips Craniofacial Anomalies Dermatology Diabetes/Endo/Metabolism Eye Care Genitourinary/Kidney High-Risk Newborn High-Risk Pregnancy Infectious Diseases Medical Genetics Mental Health Nervous System Disorders Normal Newborns Oral Health Orthopaedics Pediatric Surgery Respiratory Disorders Terminal Illness in Children Transplantation FIND A DOCTOR MAKE AN APPOINTMENT CALENDAR OF EVENTS CLINICAL TRIALS Megaloblastic anemia is a type of anemia characterized by very large red blood cells. In addition to the cells being large, the inner contents of each cell are not completely developed. This malformation causes the bone marrow to produce fewer cells, and sometimes the cells die earlier than the 120-day life expectancy. Instead of being round or disc-shaped, the red blood cells can be oval. There are many causes of megaloblastic anemia, but the most common source in children occurs from a vitamin deficiency of folic acid or vitamin B-12. Other sources of megaloblastic anemia include the following:

97. Health Information
    Megaloblastic (pernicious) anemia. What is megaloblastic (pernicious) anemia? Megaloblastic What causes megaloblastic (pernicious) anemia? Megaloblastic  
    http://www.baptisthealth.net/greystone/content.jsp?pageid=P00080

98. NewYork-Presbyterian Hospital: Health A To Z: Megaloblastic (Pernicious) Anemia
    Health information about Megaloblastic (pernicious) anemia from NewYorkPresbyterian. The University Hospitals of Columbia and Cornell.  
    http://wo-pub2.med.cornell.edu/cgi-bin/WebObjects/PublicA.woa/1/wa/viewHContent?

99. Case 3
    Case 3. A white woman of 61 yrs has had increasing fatigue for 3 months, and tingling in her feet for 2 weeks. Blood Count (CBC) (M)*.  
    http://meds.queensu.ca/medicine/deptmed/hemonc/anemia/Quiz/case3.htm
    
    Extractions: Blood Count (CBC) (M) *Figures in square brackets indicate normal values WBC x 10 /L Hb g/L MCV fl Platelets x 10 /L Neuts x 10 /L Lymphs x 10 /L Monos x 10 /L Eos x 10 /L Basos x 10 /L Blasts x 10 /L Promyleocytes x 10 /L Myelocytes x10 /L Metamyelocytes x 10 /L Nucleated RBC x 10 /L Film comment oval macrocytes++ hypersegmented neutrophils

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