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Pernicious Anemia: more books (94)

TREATMENT OF PERNICIOUS ANEMIA BY A SPECIAL DIET Nobel Prize Medicine 1934 by George Richards (1885-1950) and Murphy, William Parry (1892-1987) Minot, 1927-01-01
Observations on the Etiologic Relationship pf Achylia Gastrica to Pernicious Anemia. by William Bosworth. CASTLE, 1929
Some aspects of the diagnosis of pernicious anemia by George Richards Minot, 1935
ANEMIA IN PRACTICE Pernicious Anemia. by William P. Nobel Laureate in Medicine or Physiology. MURPHY, 1939
Observations on the Etiologic Relationship to Achylia Gastrica to Pernicious Anemia. Contained in The American Journal of Medical Sciences, Volume 178 pages 748-777. by William B. Castle , 1929-01-01
The Anemias -With Special Reference to Pernicious Anemia and the Use of Liver Extracts in the Treatment of Anemias; SUPPLEMENT BLOOD MORPHOLOGY IN DIAGNOSIS (HARDOVER)
Nutritional Anemias: Scurvy, Pernicious Anemia, Iron Deficiency Anemia, Folate Deficiency, Megaloblastic Anemia
The anemias. With special reference to pernicious anemia and the use of liver extracts in the treatment of anemias. Supplement Blood morphology in diagnosis. A series of six articles reprinted from the Physician's Bulletin.
Gale Encyclopedia of Medicine: Pernicious anemia by Rosalyn Carson-DeWitt MD, 2002-01-01
The Anemias - With Special Reference to Pernicious Anemia and the use of Liver Extracts in the tratment of Anemias
Acquired Chronic Acholuric Jaundice, with a Blood Picture at One Time Resembling that of Pernicious Anemia. by F. Parkes Weber, 1909
The anemias. With special reference to pernicious anemia and the use of liver extracts in the treatment of anemias. Supplement Blood morphology in diagnosis. A series of six articles reprinted from the Physician's Bulletin.
Pernicious anemia: presentations mimicking acute leukemia.(Case Report): An article from: Southern Medical Journal by Cristi Aitelli, Lori Wasson, et all 2004-03-01
THE ANEMIAS WITH SPECIAL REFERENCE TO PERNICIOUS ANEMIA AND THE USE OF LIVER EXTRACTS IN THE TREATMENT OF ANEMIAS by No Author, 1930

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Pernicious Anemia And B12 Injections
Subscribe now . pernicious anemia and B12 Injections. When I was finally diagnosed with having pernicious anemia (PA), I was 29 years old.
http://healthlink.mcw.edu/article/880000064.html

Extractions: Subscribe now >> Q: I became anemic when my daughter was born in 1940. When I was finally diagnosed with having pernicious anemia (PA), I was 29 years old. My daughter also has P.A. It was diagnosed when she was 48. I have been on B12 many years - I am now almost 80. I receive monthly B12 injections, and would like to know if I still need these every month? My doctors don't check on the need as with other medication A: If you were diagnosed with PA at such a young age, chances are you need the B12 replacement now, at the age of 80, more than ever. In a survey of 548 older people, ages 67-96, about 20% had low levels of B12 on blood tests. Only half of those people were actually anemic, so they and their doctors were probably unaware of the B12 deficiency. Adequate B12 is important for other reasons than just prevention of anemia. The nervous system also utilizes B12, so a lack of B12 can result in numbness and tingling of the hands and feet, memory loss, disorientation, depression, and even personality change. Older people may have lower levels of B12 because they do not adequately absorb B12 from their food. Once malabsorption starts, the person will become deficient in one to two years. The best way to replace B12 is through injections. Pills are available but would not be absorbed any better than B12 in food unless given in fairly high doses. The usual dose is 1 mg per month given by injection. Ask your doctor to measure your blood level of B12. Most likely you will continue to require a monthly shot
AllRefer Health - Pernicious Anemia (Congenital Pernicious Anemia, Juvenile Pern
pernicious anemia (Congenital pernicious anemia, Juvenile pernicious anemia, Macrocytic Achylic Anemia, Vitamin B12 Deficiency (Malabsorption)) information
http://health.allrefer.com/health/pernicious-anemia-info.html

Extractions: AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia Go To Main Page Alternate Names : Congenital Pernicious Anemia, Juvenile Pernicious Anemia, Macrocytic Achylic Anemia, Vitamin B12 Deficiency (Malabsorption) Definition Anemia is a condition where red blood cells are not providing adequate oxygen to body tissues. There are many types and causes of anemia. (See the general article - anemia .) Pernicious anemia is caused by a lack of intrinsic factor, a substance needed to absorb vitamin B12 from the gastrointestinal tract. Vitamin B12, in turn, is necessary for the formation of red blood cells.
HealthCentral - General Encyclopedia - Pernicious Anemia
General Health Encyclopedia, pernicious anemia. Congenital pernicious anemia is inherited as an autosomal recessive disorder. Pernicious
http://www.healthcentral.com/mhc/top/000569.cfm

Extractions: TOPIC CENTERS Choose a topic Acne Alcohol Allergies Alternative Medicine Alzheimer's Anemia Arthritis Asthma Baby and Toddler Health Back Care Bipolar Disorder Birth Control Bodywork and Mind/Body Bowel Breast Cancer Cancer Overview Caregiving Chemotherapy Children's Health Cholesterol Circumcision Colds and Flus Colon Cancer Cosmetic Surgery Crohn's Disease Dental Depression Diabetes Diet Drugs Digestion Disabilities Drugs and Medications Eating Disorders Eczema Erectile Dysfunction Eye and Vision Fitness Foot Care GERD/Heartburn Hair Loss Hearing Heart and Circulation Hepatitis Herbs Herpes High Blood Pressure HIV and AIDS Home Remedies Hyperactivity and ADD Immunizations/Vaccines Impotence Incontinence/Bladder Infertility Leukemia Lung Cancer Medical Breakthroughs Medical Expenses Medical Marijuana Men's Health Menopause Mental Health Migraines and Headaches Multiple Sclerosis Nutraceuticals Nutrition and Healthy Eating Osteoporosis Pain Management Parenting Parkinson's Pregnancy and Childbirth Prostate Cancer Prostate Disorders Psoriasis Rheumatoid Arthritis Safety and First Aid Schizophrenia Senior Health Sex and Relationships Sexual Health Skin and Hair Sleep Disorders Smoking Stress Reduction Stroke Substance Abuse and Addiction Teen Health Thyroid Disorders Travel Health Vitamins and Supplements Weight Loss Women's Health Women's Reproductive Cancers Yeast Infection Yoga Search Tips
Vitamin B12 Deficiency (Pernicious Anemia) Articles, Support Groups, And Resourc
Vitamin B12 Deficiency (pernicious anemia) articles, support groups, and resources for patients from Med Help International (www.medhelp.org).
http://www.medhelp.org/HealthTopics/Vitamin_B12_Deficiency.html

Extractions: A B C D ... Z Medical Glossary: PERNICIOUS ANEMIA VITAMIN B12 DEFICIENCY Ask The Doctor Forums Guillain Barre or vitamin B12 deficiency and PN? (Neurology and Neurosurgery Forum) pernicious anemia (Neurology and Neurosurgery Forum) Pernicious Anemia and Blood Group A (Gastroenterology and Liver Diseases Forum) pernicious anemia and neuropathy (Neurology and Neurosurgery Forum) ... [Patient Network] Revised: 6/2/2004
UAB Health System | Pernicious Anemia
pernicious anemia. Dear Doctor Column, November 26, 2001. Question What is the difference in pernicious anemia and B12 deficiency? What causes this condition?
http://www.health.uab.edu/show.asp?durki=61520&site=734&return=18687
RxMed: Illness Information - ANAPHYLAXIS
The symptoms of pernicious anemia develop slowly and gradually and may not be immediately recognized . Family history of pernicious anemia. Genetic factors.
http://www.rxmed.com/b.main/b1.illness/b1.1.illnesses/anemia,_pernicious.html

Extractions: Vitamin B-12 is found in foods of animal origin, such as meat, fish, dairy products and legumes.. Causes: Prevention: See diagnosis and treatment below. Weakness and tiredness Bleeding gums Nausea, appetite loss and weight loss Sore tongue Numbness and tingling in the hands and feet Difficulty maintaining balance Yellowish tinge to eyes and skin Shortness of breath Poor memory Headache Depression Confusion and dementia Risk Factors Improper diet, especially a vegetarian diet lacking vitamin B-12 and without supplements
Information About Vitamin B12 Deficiency
What is pernicious anemia? pernicious anemia is a rare condition in which the body does not absorb enough vitamin B12 from the digestive tract.
http://www.mamashealth.com/blood/peranemia.asp

Extractions: What is Pernicious Anemia? Pernicious anemia is a rare condition in which the body does not absorb enough vitamin B12 from the digestive tract. It causes inadequate production of red blood cells. Vitamin B12 is needed to make red blood cells. Pernicious anemia is hereditary. It is rarely caused by a diet lacking in vitamin B12. Vitamin B12 is found in meat, eggs, shellfish, fortified cereals and milk. Pernicious anemia is a chronic condition what progresses steadily if not treated. Symptoms? In early stages, there are usually no symptoms. When symptoms do appear, the most common ones are: What causes Pernicious Anemia? It most common causes is inheriting it from your parents. Other causes include: surgery to the stomach, surgery to the small intestine, abnormal bacterial growth in the small intestine, Crohn's Disease, and celiac disease. Pernicious anemia may also be associated with type 1 diabetes , thyroid disease, and a family history of the pernicious anemia.
Pernicious Anemia
pernicious anemia. Definition. pernicious anemia is a disease in which the red blood cells are abnormally formed, due to an inability to absorb vitamin B 12 .
http://www.ehendrick.org/healthy/001049.htm

Extractions: Resources Pernicious anemia is a disease in which the red blood cells are abnormally formed, due to an inability to absorb vitamin B . True pernicious anemia refers specifically to a disorder of atrophied parietal cells leading to absent intrinsic factor, resulting in an inability to absorb B Vitamin B , or cobalamin, plays an important role in the development of red blood cells. It is found in significant quantities in liver, meats, milk and milk products, and legumes. During the course of the digestion of foods containing B , the B becomes attached to a substance called intrinsic factor. Intrinsic factor is produced by parietal cells which line the stomach. The B -intrinsic factor complex then enters the intestine, where the vitamin is absorbed into the bloodstream. In fact, B can only be absorbed when it is attached to intrinsic factor. In pernicious anemia, the parietal cells stop producing intrinsic factor. The intestine is then completely unable to absorb B . So, the vitamin passes out of the body as waste. Although the body has significant amounts of stored B
Pernicious Anemia
pernicious anemia,. pernicious anemia occurs most often in persons older than 35 years and is more common in individuals of northern European descent.
http://www.britannica.com/nobel/micro/460_52.html

Extractions: slow-developing disease in which the production of red blood cells is impaired as the result of a vitamin B deficiency. An absence of hydrochloric acid in gastric secretions (achlorhydria) is also characteristic of this condition. Pernicious anemia is one of many types of anemia, a disease marked by a reduction in red blood cells or in the oxygen-carrying substance hemoglobin found in those cells. Anemias are distinguished from one another by cause, symptoms, and cell characteristics. In pernicious anemia, vitamin B , which is necessary for red blood cells to mature properly in the bone marrow, is unavailable owing to a lack of intrinsic factor, a substance responsible for the intestinal absorption of the vitamin. In a healthy person, intrinsic factor is produced by the parietal cells of the stomach, the cells that also secrete hydrochloric acid. In the stomach, intrinsic factor forms a complex with vitamin B . This complex remains intact, preventing degradation of the vitamin by intestinal juices, until it reaches the ileum of the small intestine, where the vitamin is released and absorbed into the body. Pernicious anemia results either when intrinsic factor is prevented from binding with vitamin B or when the parietal cells are unable to produce intrinsic factor. This is believed to stem from an autoimmune reaction in which the body produces antibodies against intrinsic factor and against the parietal cells, destroying them.
Pernicious Anemia - Information / Diagnosis / Treatment / Prevention
home blood disorders anemia pernicious pernicious anemia. Adam.com An Overview Looks at pernicious anemia, its causes, incidence and risk factors.
http://www.healthcyclopedia.com/blood-disorders/anemia/pernicious.html

Extractions: Web Directory: Adam.com: An Overview Looks at pernicious anemia, its causes, incidence and risk factors. Anemia Cases A case study of a 50 year old woman complaining of anorexia and shortness of breath for the past few weeks. InteliHealth: Pernicious Anemia Details about this disorder, what it is, the symptoms, diagnosis, prevention, treatment, prognosis and when to call a doctor.
Pernicious Anemia
pernicious anemia. Definition Vitamin B12, in turn, is necessary for the formation of red blood cells. pernicious anemia is a type of megaloblastic anemia.
http://www.healthscout.com/ency/article/000569.htm

Extractions: Channels Home Today Women Men ... Drug Checker Advertisement Disease Injury Nutrition Poison ... Prevention Definition: Anemia is a condition where red blood cells are not providing adequate oxygen to body tissues. There are many types and causes of anemia. (See the general article - anemia .) Pernicious anemia is caused by a lack of intrinsic factor, a substance needed to absorb vitamin B12 from the gastrointestinal tract. Vitamin B12, in turn, is necessary for the formation of red blood cells. Pernicious anemia is a type of megaloblastic anemia Causes, incidence, and risk factors: Intrinsic factor is a protein the body uses to absorb vitamin B12. When gastric secretions do not have enough intrinsic factor, vitamin B12 is not adequately absorbed, resulting in pernicious anemia. Because vitamin B12 is needed by nerve cells and blood cells for them to function properly, pernicious anemia causes a wide variety of symptoms, including fatigue, shortness of breath, tingling sensations, difficulty walking, and diarrhea.
What Is Pernicious Anemia?
pernicious anemia, a potentially fatal nutritional deficiency, is easily treated by regular intramuscular injections of vitamin B12.
http://akak.essortment.com/whatispernicio_rtxl.htm

Extractions: What is pernicious anemia? Pernicious anemia, a potentially fatal nutritional deficiency, is easily treated by regular intramuscular injections of vitamin B-12. Pernicious anemia is a potentially fatal nutritional deficiency cause by the body's inability to absorb vitamin B-12, which is essential to the body's production of red blood cells. Pernicious anemia is caused by the absence of intrinsic factor, a substance secreted by the stomach. Intrinsic factor facilitates the absorption of vitamin B-12. A blood test can confirm a diagnosis of pernicious anemia, by revealing the presence of megaloblasts in the blood. A megaloblast is a large erythroblast, and an erythroblast is the first identifiable stage in the development of a red blood cell. In pernicious anemia, the number of red blood cells decreases, but their size and hemoglobin content increases. bodyOffer(19807) Because the body stores B-12 very efficiently, it takes years for pernicious anemia to develop and for symptoms to begin to show. What are the symptoms of pernicious anemia?
Pernicious Anemia - Medical Dictionary Definitions Of Popular Medical Terms
MedicineNet Home MedTerms medical dictionary AZ List pernicious anemia. pernicious anemia A blood disorder caused by inadequate vitamin B12 in the blood.
http://www.medterms.com/script/main/art.asp?articlekey=4847
Anemia, Pernicious - Medical Dictionary Definitions Of Popular Medical Terms
pernicious anemia is characterized by the presence in the blood of large, immature, nucleated cells (megaloblasts) that are forerunners of red blood cells.
http://www.medterms.com/script/main/art.asp?articlekey=6855
Megaloblastic (Pernicious) Anemia - Lucile Packard Children's Hospital
pernicious) anemia? Megaloblastic anemia, also called pernicious anemia, is a type of anemia characterized by very large red blood cells.
http://www.lpch.org/DiseaseHealthInfo/HealthLibrary/hematology/megalob.html

Extractions: What is megaloblastic (pernicious) anemia? Megaloblastic anemia, also called pernicious anemia, is a type of anemia characterized by very large red blood cells. In addition to the cells being large, the inner contents of each cell are not completely developed. This malformation causes the bone marrow to produce fewer cells, and sometimes the cells die earlier than the 120-day life expectancy. Instead of being round or disc-shaped, the red blood cells can be oval. What causes megaloblastic (pernicious) anemia? There are many causes of megaloblastic anemia, but the most common source in children occurs from a vitamin deficiency of folic acid. Other sources of megaloblastic anemia include the following: digestive diseases Certain diseases of the lower digestive tract can lead to megaloblastic anemia. These include celiac disease, chronic infectious enteritis, and enteroenteric fistulas. malabsorption Inherited congenital folate malabsorption, a genetic problem in which infants cannot absorb folic acid in their intestines, can lead to megaloblastic anemia. This requires early intensive treatment to prevent long term problems such as mental retardation.
Pernicious Anemia
Health Channels. Family child health. Men s health. Women s health. Seniors health. Addiction. Allergy NEW! Arthritis. Back health. Brain health. Breast cancer.
http://www.medbroadcast.com/condition_info_details.asp?disease_id=278
Perniciuos Anemia
pernicious anemia. (Transcobalamin II deficiency). Pathology. pernicious anemia (PA) is caused by a lack of vitamin B 12 , otherwise known as cobalamin.
http://www.diseasedir.org.uk/genetic/gene2202.htm

Extractions: Chromosomes: Pathology Pernicious anemia (PA) is caused by a lack of vitamin B , otherwise known as cobalamin. Diced liver has been known since 1926 to cure PA. The active agent at this time was unknown, Eventually in 1948, the active agent was isolated, and characterised. The active agent, being vitamin B . Cobalamin is composed of a carbon ring, containing a cobolt atom in its centre. Cobalamin is involved in only two chemical reactions within the body (see figure 22.02.01). One involving the formation of methionine, and the other, the formation of succinate. These two reactions require modified versions of cobalamin, the methyltransferase requires a methylated cobalamin. Whereas the mutase requires an adenylated cobalamin. Defects in these two enzymes result in the symptoms of PA. Aetiology PA can be brought about by several possible defects. Cobalamin is absorbed across the gut by the secretion of a glycoprotein called "Intrinsic Factor" (IF). IF binds to cobalamin, and then facilitates cobnbalamins crossing into the blood stream through the IF receptor. Once in the blood, cobalamin is released by IF, and binds to transcobalamin II (TCII). This allows TCII, and cobalamin to be taken up by liver cells. Cobalamin is then modified by either adenylation, or methylation. Defects can arise in any of these pathways, particularly with IF, IF receptor, and TCII. A genetic defect in any of these will result in PA. A defect in the methylation/adenylation step results in much less severe symptoms.
Pernicious Anemia Review! - The Doctors Lounge(TM)
pernicious anemia. Hematology. Medical disease review for USMLE, MRCP. A quick summary before the exams. Hematology. pernicious anemia. (Addisonian anemia).
http://www.thedoctorslounge.net/clinlounge/diseases/hematology/pernicious.htm

Extractions: You are here: Back to hematological diseases index (Addisonian anemia) Autoimmune disorder in which antibodies attack the gastric mucosa (causing gastric atrophy) or intrinsic factor. This leads to inadequate absorption of intrinsic factor and hence a decrease in vitamin B12 absorption ( macrocytic anemia Clinical suspicion: macrocytic anemia due to B12 deficiency Diagnosis: Schilling test
Untitled Document
pernicious anemia, A Victory For Science. From Whipple=s study, Minot believed that the cause of pernicious anemia was some missing essential nutrient.
http://www.csulb.edu/~acolburn/SCED496/pernicious_anemia.htm

Extractions: Home ScEd 401 ScEd 550 EDSS 450C ... Contact Pernicious Anemia, A Victory For Science Anemia is a medical condition in which the blood is low in red blood cells or hemoglobin. However, in the later part of the nineteenth century, a new form of anemia was gradually identified as a distinct medical condition, termed pernicious anemia. The victim commonly exhibited an inflamed, glossy tongue, slight jaundice or yellowing of the eyes and skin, and persistent tingling or numbness in the fingers or toes. Microscopic examination of the blood revealed cells with overly large nuclei called megaloblasts (today the hallmark sign of pernicious anemia). The anemia was almost always fatal. The survival after the onset of the disease was usually from one to three years (Hardisty 1982). For over seventy years since its first recognition, pernicious anemia remained an incurable disorder with an outlook of almost certain death. It was not until 1926 when two physicians from Boston, Doctors George R. Minot and William P. Murphy announced insights into the cure of the disease. In 1925, Minot was 40 years old and an assistant professor of medicine at Harvard University. He also had a busy practice in hematology. He recruited Murphy from Peter Bent Brigham Hospital to help him with his busy practice. Minot wanted all of his office associates to have some research experience and to have published at least one paper before starting his practice. So Minot suggested to Murphy to search for some sort of dietary supplement for patients with anemia. Minot had been interested in the dietary habits in pernicious anemia patients since he graduated from Harvard Medical School. He had noticed that the victims disliked the taste of meat and had poor eating habits (Krantz 1974).
NEJM -- Pernicious Anemia With Neuropsychiatric Dysfunction In A Patient With Si
Original Article from The New England Journal of Medicine pernicious anemia with Neuropsychiatric Dysfunction in a Patient with Sickle Cell Anemia Treated
http://content.nejm.org/cgi/content/short/348/22/2204

Extractions: Full Text PDF PDA Full Text CME Exam ... Chapters at Harrison's The administration of folic acid can mask the megaloblastic anemia caused by cobalamin deficiency. More critically, this masking, although neither complete nor permanent, can permit neurologic dysfunction to develop and sometimes become irreversible. A few authors have proposed that folate may actually worsen the neurologic dysfunction. Patients with sickle cell disease are often routinely given folate supplementation. The rationale is to prevent the deficiency caused by the increased folate turnover in chronic hemolytic anemia.

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