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Myelodysplastic Syndromes: more books (49)

Myelodysplastic Syndromes, An Issue of Hematology/Oncology Clinics of North America (The Clinics: Internal Medicine) by Benjamin L. Ebert MDPhD, 2010-04-22
Myelodysplastic Syndromes by Eva Hellstrom-lindberg, 2008-08
Myelodysplastic Syndromes: Approach to Diagnosis and Treatment by Harold R. Schumacher, Sucha Nand, 1995-04
Myelodysplastic Syndrome and Cytokines: Proceedings of the International Symposium on Myelodysplastic Syndrome and Cytokine, Sapporo, 28-29 Septembe (International Congress Series) by Chicago) International Symposium on Neurohypophyseal Peptide Hormones and Other Biologically Active Peptides (1980 : University of Illinois, Fumimaro Takaku, et all 1991-06
Bone Marrow Failure Syndromes by Neal S. Young MD, Neal S., MD Young, 2000-04-21
Myelodysplastic syndrome: An entry from Thomson Gale's <i>Gale Encyclopedia of Cancer, 2nd ed.</i> by Andrea, M.D. Ruskin, 2006
Gale Encyclopedia of Cancer: Myelodysplastic syndrome by M.D. Andrea Ruskin, 2002-01-01
Hospital wins suit by family of deceased MDS Pt.(myelodysplastic syndrome): An article from: Hospital Law's Regan Report by A. David Tammelleo, 2006-07-01
Myelodysplastic Syndrome: An entry from Gale's <i>Gale Encyclopedia of Medicine, 3rd ed.</i> by Andrea, M.D. Ruskin, 2006
21st Century Complete Medical Guide to Bone Marrow Disorders, Myelodysplastic Syndromes, Myeloproliferative Disorders, Authoritative NIH and FDA Documents, ... Information for Patients and Physicians by PM Medical Health News, 2004-03
J & B Clinical Card: Myelodysplastic Syndromes Clinical Card by John M. Burke, 2008-12-18
Myeloproliferative Diseases and Myelodysplastic Syndromes (Hematology Oncology Clinics of North America, Volume 17, Number 5, October 2003)
Myelodysplastic Syndrome by Frederic P. Miller, Agnes F. Vandome, et all 2009-12-24
Myelodysplastic Syndromes (Hematology / Oncology Clinics of North America, Vol. 6, No. 3 (June, 1992))

lists with details

Myelodysplastic Syndromes
. What are myelodysplastic syndromes?Treatment statement for Patients. myelodysplastic syndromes. Get this document via a secure connection.
http://www.meb.uni-bonn.de/cancer.gov/CDR0000062723.html

Extractions: About PDQ Myelodysplastic syndromes, also called pre-leukemia or âsmolderingâ leukemia, are diseases in which the bone marrow does not function normally and not enough normal blood cells are made. The bone marrow is the spongy tissue inside the large bones in the body. The bone marrow makes red blood cells (which carry oxygen and other materials to all tissues of the body), white blood cells (which fight infection), and platelets (which make the blood clot). Normally, bone marrow cells called blasts develop (mature) into several different types of blood cells that have specific jobs in the body. Myelodysplastic syndromes occur most often in older people, but they can occur in younger people. The most common sign is anemia, which means there are too few mature red blood cells to carry oxygen. There may also be too few white blood cells in the blood to fight infections. If the number of platelets in the blood is lower than normal, this may cause people to bleed or bruise more easily. A doctor should be seen if a person bleeds without any reason, bruises more easily than normal, has an infection that wonât go away, or feels tired all the time. If there are symptoms, a doctor may order blood tests to count the number of each kind of blood cell. If the results of the blood test are not normal, the doctor may do a bone marrow biopsy. During this test, a needle is inserted into a bone and a small amount of bone marrow is taken out and looked at under the microscope. The doctor can then determine the kind of disease and plan the best treatment.
Society Patient Services - Myelodysplastic Syndrome
Myelodysplastic Syndrome, myelodysplastic syndromes (MDS) are a group of diseases that originate in an early bloodforming cell in the marrow.
http://www.leukemia-lymphoma.org/all_page?item_id=55442
ACS :: How Is Myelodysplastic Syndrome Diagnosed?
Detailed Guide Myelodysplastic Syndrome. Signs and Symptoms. myelodysplastic syndromes (MDS) can cause many different signs and symptoms.
http://www.cancer.org/docroot/cri/content/cri_2_4_3x_how_is_myelodysplastic_synd

Extractions: Signs and Symptoms Myelodysplastic syndromes (MDS) can cause many different signs and symptoms. Patients can have symptoms such as weight loss, fever, and loss of appetite. Of course, these do not occur only with MDS and are more often caused by something other than cancer. Shortages of one or more types of blood cells can cause most signs and symptoms of MDS: Excessive tiredness, shortness of breath, and pale skin can be caused by anemia (shortage of red blood cells). Serious infections with high fevers can be caused by leukopenia (not having enough normal white blood cells) and, in particular, by having neutropenia or granulocytopenia (too few mature granulocytes). Excessive bruising and bleeding, for example, frequent or severe nosebleeds and/or bleeding from the gums, can be due to thrombocytopenia (not having enough of the blood platelets needed for plugging holes in damaged blood vessels).
ACS :: Can Myelodysplastic Syndrome Be Prevented?
Some studies have shown a statistical link between smoking and the risk of developing leukemia or myelodysplastic syndromes (MDS).
http://www.cancer.org/docroot/CRI/content/CRI_2_4_2X_Can_myelodysplastic_syndrom

Extractions: Cancer Reference Information ... Treatment Decision Tools Detailed Guide: Myelodysplastic Syndrome Can Myelodysplastic Syndrome Be Prevented? Some studies have shown a statistical link between smoking and the risk of developing leukemia or myelodysplastic syndromes (MDS). Of course, nonsmokers are also less likely than smokers to develop many other specific cancers, as well as heart disease, stroke, and other diseases. Treatment of other cancers with chemotherapy and radiation may cause secondary (post-treatment) MDS. Doctors are now studying ways to minimize the risk of secondary MDS developing in patients receiving these treatments. However, the obvious benefits of treating life-threatening cancers with chemotherapy and radiation therapy must be balanced against the small chance of developing MDS several years later. Avoiding known cancer-causing industrial chemicals, such as benzene, can lower your risk of developing MDS. However, most experts agree that occupational and environmental radiation and chemicals are responsible for only a small fraction of MDS cases. Revised 6-6-03 Printer-Friendly Page Email this Page toggles = new Array(14); contents = new Array(14);
THE MERCK MANUALSECOND HOME EDITION, Myelodysplastic Syndromes
Merck Co., Inc. is a global researchdriven pharmaceutical products company. Contact us Worldwide. Home About Merck Products Newsroom
http://www.merck.com/mrkshared/mmanual_home2/sb/sb176_1.jsp
Myelodysplastic Syndrome
Myelodysplastic syndrome. myelodysplastic syndromes, In Cancer Management A Mulitdisciplinary Approach, Fourth Edition, edited by Richard Pazdur, et al.
http://www.ehendrick.org/healthy/000933.htm

Extractions: Resources Myelodysplastic syndrome (MDS) is a disease that is associated with decreased production of blood cells. Blood cells are produced in the bone marrow, and the blood cells of people with MDS do not mature normally. There are three major types of blood cells -red blood cells, white blood cells and platelets. Patients with MDS can have decreased production of one, two, or all three types of blood cells. Blood cells are used in the body for many different and important functions, such as carrying oxygen (red blood cells), fighting infection (white blood cells), and controlling bleeding (platelets). Blood cells are formed and stored in the bone marrow, which is the spongy tissue inside large bones. Stem cells, or immature blood cells, are stored in the bone marrow and have the ability to develop into all three types of mature blood cells. When the body needs a specific type of blood cell, the bone marrow uses its stockpile of stem cells to produce the kind of mature cells needed for that particular situation. In patients who have MDS, blood cells fail to mature normally. In other words, the bone marrow is unable to develop a normal amount of mature blood cells, and is also not able to increase blood cell production when mature cells are needed. Sometimes, even the cells that are produced do not function normally. The marrow eventually becomes filled with the immature cells and there is not room for the normal cells to grow and develop. MDS therefore causes a shortage of functional blood cells.
Myelodysplastic Syndromes - Information / Diagnosis / Treatment / Prevention
home blood disorders myelodysplastic syndromes myelodysplastic syndromes. Information Diagnosis Treatment Prevention.
http://www.healthcyclopedia.com/blood-disorders/myelodysplastic-syndromes.html
CancerBACUP : Myelodysplastic Syndromes
Information on the The myelodysplastic syndromes, a group of disorders affecting the bone marrow. Search. The myelodysplastic syndromes.
http://www.cancerbacup.org.uk/Cancertype/Leukaemiachronicmyeloid/Precancerouscon

Extractions: @import "/stylesheet-site.css"; Search This section gives information about a group of conditions known as the myelodysplastic syndromes. We hope that it will answer any questions you have about these conditions, but if you would like any further information please contact CancerBACUPs Cancer Support Service on , or Freephone The myelodysplastic syndromes are a group of disorders affecting the bone marrow. They are not types of cancer, although in a small number of people they can develop into a particular form of leukaemia. However, the symptoms are often very similar to those caused by cancer and the treatments used are also similar. back to top The bone marrow is the spongy material in the centre of some of our bones. It produces cells known as stem cells. Stem cells are immature cells that develop into the three different types of blood cells: Red blood cells which carry oxygen to all cells in the body.
Myelodysplastic Syndrome : 02495
DESCRIPTION. What are myelodysplastic syndromes? What are myelodysplastic syndromes? STAGE EXPLANATION. Stages of myelodysplastic syndromes.
http://www.acor.org/cnet/202495.html

Extractions: Myelodysplastic syndromes, also called pre-leukemia or "smoldering" leukemia, are diseases in which the bone marrow does not function normally and not enough normal blood cells are made. The bone marrow is the spongy tissue inside the large bones in the body. The bone marrow makes red blood cells (which carry oxygen and other materials to all tissues of the body), white blood cells (which fight infection), and platelets (which make the blood clot). Normally, bone marrow cells called blasts develop (mature) into several different types of blood cells that have specific jobs in the body. Myelodysplastic syndromes occur most often in older people, but they can occur in younger people. The most common sign is anemia, which means there are too few mature red blood cells to carry oxygen. There may also be too few white blood cells in the blood to fight infections. If the number of platelets in the blood is lower than normal, this may cause people to bleed or bruise more easily. A doctor should be seen if a person bleeds without any reason, bruises more easily than normal, has an infection that won't go away, or feels tired all the time.
Resources For Myelodysplasia And Myeloproliferative Disorders From GrannyBarb An
Resources for Myelodysplasia or myelodysplastic syndromes and Myeloproliferative Disorders. Contents. The myelodysplastic syndromes (MDS) Include. MDS Resources.
http://www.acor.org/leukemia/mpd.html

Extractions: Myelodysplastic Syndromes Myeloproliferative Disorders Resources for Myelodysplasia or Myelodysplastic Syndromes and Myeloproliferative Disorders Resources for Myelodysplasia or Myelodysplastic Syndromes Adult Myelodysplasia Patient Stories Childhood Myelodysplasia Patient Stories In Loving Memory of those who passed away from Myelodysplasia. Information on subscribing to the Aplastic Anemia and Myleodysplastic Syndrome support list (AA-MDS-Talk) mailing list Resources for Myelproliferative Disorders (MPD) Information on subscribing to the Myeloproliferative Disorders (MPD-Net) mailing list Information on subscribing to the BMT-Talk mailing list Refractory Anemia Refractory Anemia with Sideroblasts Refractory Anemia with Excess Blasts Chronic Myelomonocytic Leukemia Refractory Anemia with Excess Blasts in Transformation Preleukemia including Aplastic Anemia caused by environmental exposure PH negative Chronic Myelocytic Leukemia
Information About Myelodysplastic Syndrome
myelodysplastic syndromes are conditions where the bone marrow does not function properlly and there is a critical shortage of normally functioning blood cells
http://www.mamashealth.com/blood/myelo.asp

Extractions: What is Myelodysplastic Syndrome? Myelodysplastic syndromes are conditions where the bone marrow does not function properlly and there is a critical shortage of normally functioning blood cells. Bone marrow is the spongy tissue inside the large bones in the body. Myelodysplastic syndromes causes blood cells to mature improperly leading to fewer red blood cells, white blood cells and platelets. Myelodysplastic Syndrome can occur at any age but it is more likely to develop in people older than 60 years. It is a serious condition. It can lead to acute myelogenous leukemia Function of Bone Marrow? Bone marrow is responsible for making red blood cells, white blood cellss and platelets. Red blood cells carry oxygen and other materials to all tissues of the body. White blood cells fight infection. Platelets make the blood clot. When the bone marrow functions properly, it produces bone marrow cells called blasts. Blasts developinto several different types of blood cells that have specific jobs in the body. Signs of Myelodysplastic Syndrome?
Information About Myelodysplastic Syndrome
myelodysplastic syndromes are conditions where the bone marrow does not function properly and there is a critical shortage of normally functioning blood cells.
http://www.mamashealth.com/syndrome/myelo.asp

Extractions: What is Myelodysplastic Syndrome? Myelodysplastic syndromes are conditions where the bone marrow does not function properly and there is a critical shortage of normally functioning blood cells. Bone marrow is the spongy tissue inside the large bones in the body. Myelodysplastic syndromes causes blood cells to mature improperly leading to fewer red blood cells, white blood cells and platelets. Myelodysplastic Syndrome can occur at any age but it is more likely to develop in people older than 60 years. It is a serious condition. It can lead to acute myelogenous leukemia Function of Bone Marrow? Bone marrow is responsible for making red blood cells, white blood cellss and platelets. Red blood cells carry oxygen and other materials to all tissues of the body. White blood cells fight infection. Platelets make the blood clot. When the bone marrow functions properly, it produces bone marrow cells called blasts. Blasts developinto several different types of blood cells that have specific jobs in the body. Signs of Myelodysplastic Syndrome?
The Royal Marsden Hospital - Paediatric Information Booklets - Myelodysplastic S
myelodysplastic syndromes are disorders of the bone marrow and blood which usually affect elderly people. These disorders are very
http://www.royalmarsden.org/clinicalservices/clinicalunits/paediatric/booklets/m

Extractions: Myelodysplastic syndromes are disorders of the bone marrow and blood which usually affect elderly people. These disorders are very rare in children and their exact aetiology is unknown. Children often present with bruising because of low platelet count and recurrent infections. The diagnosis is often made by examination of the peripheral blood and the bone marrow. Further tests will be done on the bone marrow to confirm the diagnosis and the exact subtype of the disorder. Certain cytogenetic abnormalities are typically associated with these disorders and may help to predict response to treatment and outcome. The diagnosis may not be clear cut at initial presentation and an observation period may be necessary prior to any form of therapy. The treatment of these disorders has changed over the last decade. Children with myelodysplastic syndrome are usually treated with intensive chemotherapy similar to that of acute myeloblastic leukaemia (AML) (for details refer to the handout of AML) with or without BMT depending on the type of MDS and availability of a suitable BM donor.
Treatment Of Myelodysplastic Syndromes At Mayo Clinic
Treatment of myelodysplastic syndromes at Mayo Clinic. (Synonyms myelodysplasia What are myelodysplastic syndromes? myelodysplastic syndromes
http://www.mayoclinic.org/myelodysplastic/

Extractions: Home About Mayo Clinic Contact Us Mayo Clinic Locations: Arizona Florida Minnesota Mayo Clinic ... Medical Services Myelodysplastic Syndromes Myelodysplastic Syndromes Overview Treatment Options Appointments Clinical Trials ... Medical Services (Synonyms: myelodysplasia, refractory anemia, preleukemia, dysmyelopoietic syndrome) Mayo Clinic has been a world leader in the treatment of patients with bone marrow disorders, including myelodysplastic syndromes (MDS). Although myelodysplastic syndromes are relatively rare, Mayo Clinic physicians care for more than 200 patients with these syndromes each year. Patients with MDS face the risk that the disease will transform into leukemia, which can be difficult to treat. The chances of developing leukemia depend on the subtype of myelodysplastic syndromes and the specific genetic injury that occurred in the bone marrow cells. Most patients suffering from MDS live with complications from persistent low blood counts, including infection and bleeding. Many patients with myelodysplastic syndromes suffer from a variety of symptoms caused by low blood counts. Other patients have no symptoms at all. Physicians often detect MDS incidentally after performing a blood count for another reason. Hematologists diagnose MDS based on a careful review of the patient's blood under a microscope and a detailed clinical evaluation. An experienced hematopathologist also conducts a bone marrow biopsy. Careful analysis of the bone marrow chromosomes can reveal the MDS type and exclude other possible diseases. The diagnosis of MDS can be extremely difficult to make. Several other disorders can have similar blood counts and bone marrow appearance.
Research In Myelodysplastic Syndromes
Mayo Clinic Medical Services myelodysplastic syndromes. Research in myelodysplastic syndromes. Hematologists at Mayo Clinic currently
http://www.mayoclinic.org/myelodysplastic/research.html

Extractions: Home About Mayo Clinic Contact Us Mayo Clinic Locations: Arizona Florida Minnesota Mayo Clinic ... Medical Services Myelodysplastic Syndromes Myelodysplastic Syndromes Overview Treatment Options Appointments Clinical Trials ... Medical Services Hematologists at Mayo Clinic currently have an active research program dedicated to understanding myelodysplastic syndromes in the hope of improving treatments. The myeloid disease group at Mayo Clinic includes basic scientists and clinicians. Because current MDS treatments are unable to cure the disease, Mayo researchers are committed to evaluating new drug therapies. Research efforts include on-site efforts, an ongoing collaboration with the University of Oxford in the United Kingdom and cooperation with researchers at other institutions. Drugs that appear promising in the laboratory and are expected to be relatively safe are tested in clinical trials through the Mayo Clinic Cancer Center. The available list of clinical trials (opens in new window) constantly changes. Decisions about participating in a clinical trial, supportive care or other therapy depends on individual circumstances and needs. Mayo Clinic hematologists provide in-depth consultations to help each patient make the best decisions for treatment.
Myelodysplastic Syndrome
Report of an international working group to standardize response criteria for myelodysplastic syndromes. Blood. myelodysplastic syndromes.
http://www.clevelandclinicmeded.com/diseasemanagement/hematology/myelo/myelo.htm

Extractions: Medical Oncology Print Chapter The Cleveland Clinic Foundation DEFINITION Historically, myelodysplastic syndrome (MDS) has been referred to as oligoblastic leukemia, refractory anemia, smoldering acute leukemia, or preleukemia It represents a heterogeneous hematopoietic disorder derived from an abnormal multipotent progenitor cell, and is characterized by a hyperproliferative bone marrow, dysplasia of the cellular elements, and ineffective hematopoiesis. MDS can be indolent or aggressive, depending on the subclassification (discussed below). Recognition of this entity has increased over the past decade, and should be suspected in older adults with anemia, thrombocytopenia, leukopenia, or a combination of these abnormalities. Not surprisingly, morbidity and mortality result from anemia, bleeding, and infection, along with transformation to acute myelogenous leukemia (AML), which occurs in approximately one third of patients. MDS can be cured with bone marrow transplantation, a procedure prohibitively toxic in most older patients with this diagnosis. Thus, most treatments focus on alleviation of symptoms, reduction in transfusion requirements, and improvement of quality of life.
Clinical Trials For Myelodysplastic Syndromes (MDS) Treatment
myelodysplastic syndromes Clinical Trials. , 1058 phase II multicenter study of TRISENOX® (arsenic trioxide) in patients with myelodysplastic syndromes (MDS).
http://www.cticseattle.com/prod_frame-ctri-mds.htm
Clinical Trials For Myelodysplastic Syndromes (MDS) Treatment
Myelodysplatic Syndromes Clinical Trial 1061. 1061 phase I/II study of TRISENOX® (arsenic trioxide) in patients with myelodysplastic syndromes (MDS).
http://www.cticseattle.com/prod_frame-ctri-mds-1061.htm

Extractions: The purpose of this open-label, multicenter phase I/II study is to evaluate the efficacy, toxicity, and pharmacokinetic profile of TRISENOX , 0.3 mg/kg/dose for 5 doses, followed by twice weekly 0.25 mg/kg maintenance doses for a minimum of 15 weeks, in patients with myelodysplastic syndromes. Patients will be treated for a minimum of 16-weeks, with TRISENOX loading doses for 5 days in week 1 and maintenance doses twice weekly thereafter. Disease and QOL assessments will be done every 8 weeks. Safety assessments will be done at each study visit. Up to 50 four milliliter blood samples for pharmacokinetic assay will be collected during the first 16 weeks of therapy as described in Section 9, from patients who consent to this sampling. Adult patients with confirmed diagnosis (by standard FAB criteria) of a myelodysplastic syndrome: refractory anemia, refractory anemia with ringed sideroblasts, refractory anemia with excess blasts, refractory anemia with excess blasts in transformation, or chronic myelomonocytic leukemia.
Myelodysplastic Syndromes (MDS), Basic
myelodysplastic syndromes (MDS) an overview of MDS symptoms and MDS treatment options. NMDP Home, myelodysplastic syndromes (MDS), basic
http://www.marrow.org/MEDICAL/myelodysplastic_syndromes.html

Extractions: Myelodysplastic syndromes (MDS) are a group of diseases that affect the bone marrow and blood. About 12,000 new cases of MDS are diagnosed in the United States each year. Although children and young adults can have MDS, most MDS patients are over age 60. About twice as many men as women have the disease. The cause of MDS is not known, but some studies have linked it to exposure to pesticides, herbicides and the chemical benzene, which is found in unleaded gasoline. MDS is sometimes called myelodysplasia, preleukemia or smoldering leukemia. These last two terms reflect the fact that MDS can sometimes turn into leukemia, most often acute myelogenous leukemia Healthy bone marrow makes stem cells that grow into the three types of blood cells: red blood cells, white blood cells and platelets. In people with MDS, instead of sending red blood cells, white blood cells and platelets into the blood stream, the marrow makes many immature blood cells called blasts. Not only do these blast cells not work normally as red blood cells, white blood cells or platelets, they can also collect in the bone marrow, damaging it even further.
The Myelodysplastic Syndromes Trials
The myelodysplastic syndromes Trials. A RANDOMIZED TRIAL FOR PATIENTS WITH ACUTE MYELOID LEUKAEMIA OR HIGHRISK MYELODYSPLASTIC SYNDROME AGED 60 OR OVER.
http://www.lrf.org.uk/en/1/dismdstrials.html

Extractions: A RANDOMIZED TRIAL FOR PATIENTS WITH ACUTE MYELOID LEUKAEMIA OR HIGH-RISK MYELODYSPLASTIC SYNDROME AGED 60 OR OVER Trial Code: Type: Phase III Status: Open Link: http://www.controlled-trials.com/mrct/trial/MYELOD... The aim of this trial is to compare two strategies of treatment for patients with Acute Myeloid Leukaemia or High-Risk Myelodysplastic Syndrome and to compare treatment options within these two strategies. The main objective is to determine whether there are differences in response rates, survival, quality of life and supportive care requirements between the two strategies in patients where there is uncertainty as to the best treatment approach.

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