EMedicine - Hairy Leukoplakia : Article By Hunter H Sams, MD hairy leukoplakia Oral hairy leukoplakia (OHL) is an oral mucosal disease that first was described in 1984. hairy leukoplakia. Last Updated April 11, 2004, http://www.emedicine.com/med/topic938.htm
Extractions: (advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Medicine, Ob/Gyn, Psychiatry, and Surgery Oncology Last Updated: April 11, 2004 Rate this Article Email to a Colleague Synonyms and related keywords: oral hairy leukoplakia, OHL, AIDS, HIV, Epstein-Barr virus, EBV, immunosuppression, immunocompromise, homosexual men, IV drug users AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: Hunter H Sams, MD , Staff Physician, Department of Internal Medicine, Division of Dermatology, Vanderbilt University Medical Center Coauthor(s): Alan Boyd, MD , Assistant Professor, Departments of Internal Medicine, Dermatology and Pathology, Vanderbilt University Hunter H Sams, MD, is a member of the following medical societies: American Academy of Dermatology , and American Academy of Family Physicians Editor(s): Sanjiv S Agarwala, MD
OI: Oral Hairy Leukoplakia -- ÆGIS . Oral hairy leukoplakia (OHL) is often the first opportunistic to appear.Oral hairy leukoplakia. OHL Classification. virus http://www.aegis.com/topics/oi/oi-ohl.html
Extractions: "O.H.L." This is part of a series on Opportunistic Infections ("OIs"). Please note that This Page Is Just A Starting Point: who specializes in treating HIV. Finding The Latest Information: Advances in treating opportunistic infections can happen at any time, so the material on this page may be outdated. Some links in the see also section at the bottom of this page are actually special database links. They may contain information published after this page was written. virus NOTE: If you are undergoing treatment that has increased your CD4+ levels, see the important note on
EMedicine - Hairy Leukoplakia : Article Excerpt By: Hunter H Sams, MD hairy leukoplakia Oral hairy leukoplakia (OHL) is an oral mucosal disease that first was described in 1984. (advertisement). Excerpt from hairy leukoplakia. http://www.emedicine.com/med/byname/hairy-leukoplakia.htm
Extractions: (advertisement) Synonyms, Key Words, and Related Terms: oral hairy leukoplakia, OHL, AIDS, HIV, Epstein-Barr virus, EBV, immunosuppression, immunocompromise, homosexual men, IV drug users Background: Oral hairy leukoplakia (OHL) is an oral mucosal disease that first was described in 1984. It is associated with Epstein-Barr virus (EBV) and occurs almost exclusively in patients who are immunocompromised, particularly those infected with HIV. Pathophysiology: Affected mucosa has diminished numbers of Langerhans cells and T-helper cells. Keratinocytes do not contain HIV, but EBV receptors have been detected in surrounding normal mucosa. Whether OHL develops after superinfection with EBV or activation of latent infection due to reduced immune surveillance is not known. Latent membrane protein-2 (LMP-2) may regulate reactivation from latency by interfering with normal B-cell signal transduction processes, which may be important for viral persistence. Multiple strains of EBV have been demonstrated in OHL lesions. Frequency: In the US: Incidence of OHL in homosexual men and IV drug users who are infected with HIV is approximately 4%, but some evidence suggests that incidence is decreasing. The decreasing prevalence may be partially due to use of protease inhibitors. One study found that the 6-year incidence of OHL was 32% among 291 men in San Francisco who were HIV positive.
Oral Hairy Leukoplakia Ontario HIV Clinics Fact Sheet. Oral hairy leukoplakia. What is it? Oral hairy leukoplakia is a white thickening or coating of the lining of the mouth. http://www.tthhivclinic.com/oralhair.htm
Extractions: INFORMATION ON HIV Go to other sections: Select a link HIV Overview/Stages of Infection The Life Cycle of HIV Disease Symptoms Fact Sheets Symptoms: Select a link Apthous Ulcers Candidiasis Cytomegalovirus (CMV) Cryptococcal Meningitis Cryptosporidiosis Herpes Zoster (Shingles) Histoplasmosis Kaposis Sarcoma Lymphoma Mycobacterium Avium Complex (MAC) Oral Hairy Leukoplakia PAP test/PAP smear and HIV paptest PAP test/PAP smear and HIV Peripheral Neuropathy Progressive Multifocal Leukoencephalopathy (PML) Toxoplasmosis (Toxo) Wasting Ontario HIV Clinics' Fact Sheet Oral Hairy Leukoplakia What is it? Oral hairy leukoplakia is a white thickening or coating of the lining of the mouth. It looks like white vertical folds or ridges. These ridges are almost always located on the sides of the tongue, although sometimes they can be found under the tongue or on the inside of the cheek. Oral hairy leukoplakia may look like oral candidiasis (thrush). Thrush can be scraped off. The white ridges of oral hairy leukoplakia do not scape off. Oral hairy leukoplakia occurs in people who have HIV and who have moderate to severe immune system damage. What do I look for?
The Body: The Center For AIDS: RITA! -- Oral Hairy Leukoplakia: An Epstein-Barr Oral hairy leukoplakia An EpsteinBarr Virus-Associated Disease of Patients with HIV, in RITA!, from The Center for AIDS Hope and Remembrance Project, at The Body, the complete AIDS/HIV hairy leukoplakia is one of the most common, virally-induced, oral diseases of individuals with HIV infection 25%.1 2 In adults, hairy leukoplakia is more common in men3 4 http://www.thebody.com/cfa/rita_dec00/leukoplakia.html
Extractions: December 2000 Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus that infects nearly every human being by young adulthood. Most EBV infections occur asymptomatically during childhood, but EBV is associated with a wide variety of human diseases including the infectious mononucleosis syndrome, Hodgkin's lymphoma, African Burkitt's lymphoma, and nasopharyngeal carcinoma. EBV is also an opportunistic pathogen in immunocompromised patients, associated with lymphoproliferative diseases and oral hairy leukoplakia. EBV infection is transmitted from person to person by contact with infectious body fluids. Oral contact with infectious saliva is the most common route of transmission, but EBV infection may also be transmitted by sexual contact or exposure to breast milk. Like all herpesviruses, EBV establishes a life-long, persistent infection of its host. Acquisition of HIV infection stimulates reactivation of pre-existing, latent EBV infection. Asymptomatic, high level, oral EBV shedding occurs in up to 90% of HIV-infected patients, even before the clinical manifestations of immunodeficiency are apparent. While not all HIV-infected patients develop EBV-associated disease, persistent EBV replication and progressive immune dysfunction can eventually result in oral hairy leukoplakia and/or EBV-associated
Hairy Leukoplakia hairy leukoplakia in AIDS. Quick Summary. Introduction. References. Photos. Clinical Features. Histopathology. Treatment. Prognosis. The Gauley River in West Virginia, above the dam. Quick Review http://www.maxillofacialcenter.com/BondBook/mucosa/hairyleuk.html
Extractions: The Gauley River in West Virginia, above the dam. Quick Review Hairy leukoplakia is a unique whitish, irregular plaque of the side of the tongue, sometimes with surface projections long enough to appear to be "hairs" but usually with only a granular or nodular appearance. It rarely is seen at on the cheek mucosa near the corners of the lips, and look-alike lesions have been reported in HIV-negative patients, especially those with lichen planus. This lesion causes no significant problem but it is a sign of AIDS, hence, the treatment is directed at the generalized and very serious HIV virus disease. While the virus is under control, hairy leukoplakia diminishes or disappears. Most lesions have virus, bacteria and fungi within them but they are not considered contagious in the usual sense. Top of This Page Introduction Note: click on underlined words for more detail or photos. A well-demarcated, painless, verruciform hyperkeratotic lesion of the lateral tongue in HIV-infected male homosexuals was first reported in 1981 as
Extractions: Please remember that this forum is designed for educational purposes only, and experts are not engaged through this forum in rendering legal or medical advice or professional services. Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither The Body nor any sponsor is the publisher or speaker of posted visitors' questions or the experts' material. Questions and messages posted to this forum are not statements of advice, opinion, or information of The Body, Body Health Resources Corporation or any sponsor of this forum. While neither The Body nor Body Health Resources Corporation regularly reviews posted content, we reserve the right to delete, move, or edit postings if we deem it appropriate under the circumstances. Visitors submitting questions remain solely responsible for the content of their messages. Information provided by experts is general only and should not be used for diagnosing or treating a health problem or a disease, or relied upon as legal or other professional advice. This information is not a substitute for professional advice or care. If you have or suspect you may have a health or legal problem, you should consult your own health care provider or your attorney.
Hairy Leukoplakia Information Diseases Database hairy leukoplakia, Disease Database Information hairy leukoplakia Definition(s) via UMLS ..Code translations and terms via UMLS http://www.diseasesdatabase.com/sieve/item1.asp?glngUserChoice=5594
Extractions: Introduction and background. EBV infection is transmitted from person to person by contact with infectious body fluids. Oral contact with infectious saliva is the most common route of transmission, but EBV infection may also be transmitted by sexual contact or exposure to breast milk. Like all herpesviruses, EBV establishes a life-long, persistent infection of its host. Acquisition of HIV infection stimulates reactivation of pre-existing, latent EBV infection. Asymptomatic, high level, oral EBV shedding occurs in up to 90% of HIV-infected patients, even before the clinical manifestations of immunodeficiency are apparent. While not all HIV-infected patients develop EBV-associated disease, persistent EBV replication and progressive immune dysfunction can eventually result in oral hairy leukoplakia and/or EBV-associated lymphoma Epidemiology.
Hairy Leukoplakia - Information / Diagnosis / Treatment / Prevention home infectious diseases viral epstein barr virus hairy leukoplakia hairy leukoplakia. Information Diagnosis Treatment Prevention. http://www.healthcyclopedia.com/infectious-diseases/viral/epstein-barr-virus/hai
AllRefer Health - Leukoplakia (Hairy Leukoplakia, Smoker's Keratosis) Leukoplakia (hairy leukoplakia, Smoker s Keratosis) information center covers causes, prevention, symptoms, diagnosis, treatment, incidence, risk factors, signs http://health.allrefer.com/health/leukoplakia-info.html
Extractions: AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia Go To Main Page Alternate Names : Hairy Leukoplakia, Smoker's Keratosis Definition Leukoplakia is a precancerous lesion that develops on the tongue or the inside of the cheek as a response to chronic irritation. Occasionally, leukoplakia patches develop on the female external genitalia. Leukoplakia is primarily a disorder of the mucous membranes of the mouth, caused by irritation. Lesions usually develop on the tongue, but they may also appear on the insides of the cheek. Irritation may result from rough teeth or rough places on dentures, fillings, crowns and so on. It may also result from smoking or other tobacco use (smoker's keratosis). Pipe smoking involves a high risk for development of leukoplakia, as does holding chewing tobacco or snuff in the mouth for a prolonged period of time.
Extractions: AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia Go To Main Page Alternate Names : Hairy Leukoplakia, Smoker's Keratosis Leukoplakia Prognosis (Expectations) Leukoplakia is usually harmless, and lesions usually clear in a few weeks or months after the source of irritation is removed. Approximately 3% of leukoplakia lesions develop cancerous changes.
AllRefer Health - Leukoplakia Prognosis (Expectations) (Hairy Leukoplakia, Smoke Leukoplakia (hairy leukoplakia, Smoker's Keratosis) information center covers Prognosis (Expectations). of leukoplakia lesions develop cancerous changes. hairy leukoplakia is often a sign of http://www.1uphealth.com/health/leukoplakia_prognosis.html
Extractions: AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia Go To Main Page Alternate Names : Hairy Leukoplakia, Smoker's Keratosis Leukoplakia Prognosis (Expectations) Leukoplakia is usually harmless, and lesions usually clear in a few weeks or months after the source of irritation is removed. Approximately 3% of leukoplakia lesions develop cancerous changes.
Hairy Tongue Or Hairy Leukoplakia? Hairy Tongue or hairy leukoplakia? My doctor has diagnosed me with fuzzy tongue disease. What is it, what causes it, and how do I get rid of it? S. http://www.ivillagehealth.com/experts/ent/qas/0,,416906_175551,00.html
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Hairy Tongue Or Hairy Leukoplakia? Hairy Tongue or hairy leukoplakia? continued from page 1 So why does your tongue look hairy? Keratin. Keratin is one of the http://www.ivillagehealth.com/experts/ent/qas/0,,416906_175551-2,00.html
Extractions: Choose one Acupuncture Allergies Alzheimer's Disease Androgen Anxiety Disorders Asthma Atherosclerosis Attention Deficit Bacterial Vaginosis Biofeedback Bipolar Disorder Birth Control Pills Blood Donation Breast Cancer Caregiving Cervical Cancer Chiropractic Chlamydia Cholesterol Chronic Fatigue Clinical Trials Colon Cancer Contraception Depression Diabetes Dry Eye Syndrome Eating Disorders Endometriosis Epilepsy Estrogen Fibroids Fibromyalgia Fitness Flu/Colds Gastroesophageal General Women's Health Genetic Testing Genital Herpes Glaucoma Gonorrhea HIV/AIDS Health Insurance Heart Disease Hepatitis High Blood Pressure Homeopathy Human Papillomavirus Hypnosis Hysterectomy Incontinence Infertility Irritable Bowel Legal Health Tools Liposuction Lung Cancer
Oral Hairy Leukoplakia Detection of EpsteinBarr virus (EBV) DNA and antigens in oral mucosa of renal transplant patients without clinical evidence of oral hairy leukoplakia (OHL). http://www.thedoctorsdoctor.com/diseases/oralhairyleukoplakia.htm
Extractions: Background This interesting disease is found primarily in patients with a severe immunodeficiency such as in patients with AIDS. It presents with flat to hairy white lesions on the lateral or ventral borders of the tounge. It is asymptomatic and related to a patient's immune status. EPIDEMIOLOGY CHARACTERIZATION INCIDENCE 20% of asymptomatic HIV infected patients Detection of Epstein-Barr virus (EBV) DNA and antigens in oral mucosa of renal transplant patients without clinical evidence of oral hairy leukoplakia (OHL). Ammatuna P, Capone F, Giambelluca D, Pizzo I, D'Alia G, Margiotta V. Department of Hygiene and Microbiology, University of Palermo, Italy. J Oral Pathol Med 1998 Oct;27(9):420-7 Abstract quote The use of the polymerase chain reaction (PCR) to detect the presence of Epstein-Barr virus (EBV) DNA in oral mucosa in the absence of specific lesions gives rise to the problem of identifying the real viral replication sites. Hybridization with the EBV-specific probe was observed in 40/ 89 and 2/13 samples, respectively. Latent antigens (with or without lytic antigens) were detected in only 23 of the 40 samples (collected from eight different transplant patients) that were positive by in situ hybridization. Our data show that EBV is more frequently present in the oral mucosa of immunodeficient patients (where it can efficiently replicate) than in normal subjects.
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