Ride For Life: New Gene For Rare Inherited Paralysis May Aid ALS New Gene for Rare Inherited paralysis May Aid ALS. Posted October 3, 2003 in is nocure for HSP, which is also sometimes called familial spastic paraparesis or http://www.rideforlife.com/archives/000647.html
Extractions: Merion Publications A single mutation in a single gene is enough to slowly rob people of their ability to walk, scientists from the University of Michigan and the University of Pennsylvania report today. And while the inherited defect itself is rare, its discovery may help researchers unravel the mysteries of much more common paralyzing conditions, from spinal cord injury to Lou Gehrig's disease. In a paper published online today in the American Journal of Human Genetics, and scheduled for the journal's October issue, the U-M and Penn team describes a new gene, called NIPA1, for a form of hereditary spastic paraplegia, or HSP. HSP is the name given to a group of disorders affecting about 20,000 Americans. HSP gradually disables its victims as long nerve cells in the spinal cord degenerate and muscles weaken and become spastic. It is often misdiagnosed as other nerve disorders, including multiple sclerosis, cerebral palsy, and amyotrophic lateral sclerosis (also called Lou Gehrig's disease). There is no cure for HSP, which is also sometimes called familial spastic paraparesis or Strumpell-Lorain disease. Treatment is limited to physical therapy and exercise to help retain as much muscle function as possible, drug treatment to tame spastic muscle movements, and medication to treat patients' bladder and bowel control problems, and depression.
PubMed Medline Query 4 Swiss families with the pure form of hereditary spastic spinal paralysis. See RelatedArticles Clinical heterogeneity of familial spastic paraplegia linked http://perso.wanadoo.fr/asl.spastic/fichierslies/medline.htm
New Gene For Rare Inherited Paralysis May Aid Other Spinal Cord Research, Too New gene for rare inherited paralysis may aid other spinal cord research, too. nocure for HSP, which is also sometimes called familial spastic paraparesis or http://www.focusonals.com/new_gene_for_rare_inherited_paralysis_may_aid_other_sp
Extractions: University of Michigan Health System ANN ARBOR, MI A single mutation in a single gene is enough to slowly rob people of their ability to walk, scientists from the University of Michigan and the University of Pennsylvania report today. And while the inherited defect itself is rare, its discovery may help researchers unravel the mysteries of much more common paralyzing conditions, from spinal cord injury to Lou Gehrig's disease. In a paper published online today in the American Journal of Human Genetics, and scheduled for the journal's October issue, the U-M and Penn team describes a new gene, called NIPA1, for a form of hereditary spastic paraplegia, or HSP. HSP is the name given to a group of disorders affecting about 20,000 Americans. HSP gradually disables its victims as long nerve cells in the spinal cord degenerate and muscles weaken and become spastic. It is often misdiagnosed as other nerve disorders, including multiple sclerosis, cerebral palsy, and amyotrophic lateral sclerosis (also called Lou Gehrig's disease). There is no cure for HSP, which is also sometimes called familial spastic paraparesis or Strumpell-Lorain disease. Treatment is limited to physical therapy and exercise to help retain as much muscle function as possible, drug treatment to tame spastic muscle movements, and medication to treat patients' bladder and bowel control problems, and depression.
Hum. Mol. Genet. -- Abstracts: Hentati Et Al. 3 (8): 1263 Tanguy, and E. Bertini Infantile ascending hereditary spastic paralysis (IAHSP)Clinical features of a new locus for recessive familial spastic paraparesis to http://hmg.oupjournals.org/cgi/content/abstract/3/8/1263
Extractions: Department of Neurology, Northwestern University Medical School, Chicago, IL 60611. 'Pure' familial spastic paraplegias (FSP) are neurodegenerative disorders that are clinically characterized by progressive spasticity of the lower limbs and are inherited as autosomal dominant (DFSP) or autosomal recessive (RFSP) traits. The primary defect in FSP is unknown. Genetic linkage analysis was applied to five RFSP families from Tunisia. In four of these
HEALTHMEDNET familial Non Hemolytic Non Obstructive Jaundice. familial Periodic paralysis.familial Polyposis. familial spastic Paraparesis. familial Tremor. Family Health. http://www.epscorp.com/healthmednet/f.htm
Extractions: The names were derived from the specific illness/disease source directories. Therefore, there are some variations in the names. When ordering a list of URLs for your illness/disease, where possible, include the general usage, technical, acronym, and/or abbreviation names. Fabry Disease Facelifts Facet Degeneration (Low Back Pain) Facet Joint Problems Facial and Head Injuries Facial Asymmetry Facial Dermatoses Facial Hemiatrophy Facial Infection Facial Injuries (Cheek, Chin, or Jaw) Facial Injury: First Aid Facial Nerve Paralysis Facial Nerve Problems Facial Nerve Weakness or Paralysis (Bell's Palsy) Facial Neuralgia (Tic Douloureux) Facial Pain Facial Pain and Sinus Pain Facial Palsy Facial Paralysis Facial Tics Facioscapulohumeral Facioscapulohumeral Muscular Dystrophy (Landouzy-Dejerine) Facio-Scapulo-Humeral-Muscular D. Factitious Disorders Factitious Hyperthyroidism Factitous Disorder Factor II Deficiency Factor IX Deficiency Factor IX Hemophilia Factor V Deficiency Factor VII Deficiency Factor VIII Deficiency Hemophilia Factor X Deficiency Factor XII (Hageman Factor) Deficiency Factor XIII Deficiency Fahr's Disease Fahr's Syndrome Failure failure to thrive Fainting Fainting and Dizziness Fainting- What Causes It Fainting: Action Fainting: First Aid Fairbank Disease Falciparum Malaria Fall Allergies Fallopian Tube Fallopian tube procedures [in Infertility] Fallot's Tetrology Falls Falls and Hip Fractures Falls, Old Age
Children's Neurobiological Solutions New Gene For Rare Inherited paralysis May Aid Other Spinal Cord Research, Too nocure for HSP, which is also sometimes called familial spastic paraparesis or http://www.cnsfoundation.org/newsletter/newsletter_47/newsletter_06.html
Extractions: HSP is the name given to a group of disorders affecting about 20,000 Americans. HSP gradually disables its victims as long nerve cells in the spinal cord degenerate and muscles weaken and become spastic. It is often misdiagnosed as other nerve disorders, including multiple sclerosis, cerebral palsy, and amyotrophic lateral sclerosis (also called Lou Gehrig's disease).
Neurology -- Abstracts: Murillo Et Al. 53 (1): 50 To characterize a new gene locus for familial spastic paraparesis (FSP Tanguy, andE. Bertini Infantile ascending hereditary spastic paralysis (IAHSP) Clinical http://www.neurology.org/cgi/content/abstract/53/1/50
Extractions: Articles H. Kobayashi, MD, PhD E. Pegoraro, MD, PhD G. Galluzzi, PhD G. Creel, MD C. Mariani, MD E. Farina, MD E. Ricci, MD G. Alfonso, MD R. M. Pauli, MD, PhD and E. P. Hoffman, PhD ehoffman@cnmc.org OBJECTIVE: To characterize a new gene locus for familial spastic paraparesis (FSP). BACKGROUND: FSP is a genetically heterogeneous group of upper motor neuron syndromes. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked disorder. Four loci
Neurologic Manifestations Christopher Reeve paralysis Foundation. Cure paralysis Now. Worlds Wheelchair Culture. Hereditaryspastic Paraplegia/familial spastic Paraperesis C Stapley. http://www.mic.ki.se/Diseases/C10.597.html
Extractions: Diseases and Disorders Links pertaining to Neurologic Manifestations Alert! Patients and laypersons looking for guidance among the target sources of this collection of links are strongly advised to review the information retrieved with their professional health care provider. Start Page Contents: Agnosia Amnesia Aphasia Apraxias ... Vertigo Cerebellar Ataxia Classification of Ataxias - Washington U./School of Med. (US) Hereditary Ataxia Overview - GeneTests The US National Ataxia Foundation - Minneapolis European Federation of Hereditary Ataxias Int'l Network of Ataxia Friends De ADCA-Vereniging Nederland [cerebellar atrophy/ataxia syndrome] - (NL) About Episodic Ataxia [Mark ? ]
Full Listing DEFECTS AND ABNORMALITIES, BRACHIAL PLEXUS paralysis, BRAIN INJURED familial HYPERCHOLESTEROLAEMIA,familial HYPERLIPIDAEMIA, familial spastic PARAPLEGIA, FAMILY http://www.doctor.gp/help/full_listing.htm
Entrez PubMed This syndrome probably represents a new type of familial spastic paraparesis. Musclespasticity/metabolism; paralysis/genetics*; paralysis/metabolism; http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3
Volume 67 January - December 1944 A form of familial presenile dementia with spastic paralysis. C . WorsterDrought, JG . Greenfield and WH . McMenemey. Pages 38 - 43. http://www3.oup.co.uk/jnls/supplements/braini/hdb/Volume_67/Issue_01/670038.sgm.
Volume 63 January - December 1940 A form of familial presenile dementia with spastic paralysis. C . WorsterDrought, JG . Greenfield and WH . McMenemey. Pages 237 - 254. http://www3.oup.co.uk/jnls/supplements/braini/hdb/Volume_63/Issue_03/630237.sgm.
Entrez PubMed screening of the ALS2 gene in sporadic and familial amyotrophic lateral in a homogeneousphenotype of infantileonset ascending spastic paralysis with bulbar http://ghr.nlm.nih.gov/gene=als2/show/PubMed
Extractions: Limits: 10 Years Summary Brief Abstract Citation ASN.1 MEDLINE XML UI List LinkOut Related Articles Cited in Books CancerChrom Links Domain Links 3D Domain Links GEO DataSet Links Gene Links Genome Links GEO Links HomoloGene Links Nucleotide Links OMIM Links PMC Links Cited in PMC PopSet Links Protein Links SNP Links Structure Links UniSTS Links Show: Sort Author Journal Pub Date Text File Clipboard E-mail Order Items 1-20 of 23 of 2 Next Green CB, Cheng G, Chandra J, Mukherjee P, Ghannoum MA, Hoyer LL. Related Articles, Links RT-PCR detection of Candida albicans ALS gene expression in the reconstituted human epithelium (RHE) model of oral candidiasis and in model biofilms.
Entrez PubMed No abstract, Juvenile familial amyotrophic lateral sclerosis two siblings. Abstract,Infantileonset ascending hereditary spastic paralysis is associated with http://ghr.nlm.nih.gov/condition=amyotrophiclateralsclerosistype2/show/PubMed
Extractions: Limits: 5 Years Summary Brief Abstract Citation ASN.1 MEDLINE XML UI List LinkOut Related Articles Cited in Books CancerChrom Links Domain Links 3D Domain Links GEO DataSet Links Gene Links Genome Links GEO Links HomoloGene Links Nucleotide Links OMIM Links PMC Links Cited in PMC PopSet Links Protein Links SNP Links Structure Links UniSTS Links Show: Sort Author Journal Pub Date Text File Clipboard E-mail Order Items 1-16 of 16 One page. Hand CK, Devon RS, Gros-Louis F, Rochefort D, Khoris J, Meininger V, Bouchard JP, Camu W, Hayden MR, Rouleau GA. Related Articles, Links Mutation screening of the ALS2 gene in sporadic and familial amyotrophic lateral sclerosis.
