NINDS Soto's Syndrome Information Page Also known as cerebral gigantism, an information sheet compiled by NINDS. http://www.ninds.nih.gov/health_and_medical/disorders/sotos.htm
Extractions: Soto's syndrome is a rare genetic disorder characterized by excessive physical growth during the first 2 to 3 years of life. The disorder may be accompanied by mild mental retardation, delayed motor, cognitive, and social development, hypotonia (low muscle tone), and speech impairments. Children with Soto's syndrome tend to be large at birth and are often taller, heavier, and have larger heads (macrocrania) than is normal for their age. Symptoms of the disorder, which vary among individuals, include a disportionately large and long head with a slightly protrusive forehead, large hands and feet, hypertelorism (an abnormally increased distance between the eyes), and downslanting eyes. Clumsiness, an awkward gait, and unusual aggressiveness or irritability may also occur. Although most cases of Soto's syndrome occur sporadically, familial cases have also been reported.
Sotos' Syndrome (www.whonamedit.com) Sotos' syndrome A syndrome of excessive growth during the first 4 to 5 years of life, cerebral gigantism, acromegalic features, and mild mental retardation and defective coordination. Also known http://www.whonamedit.com/synd.cfm/2464.html
Extractions: This survey of medical eponyms and the persons behind them is meant as a general interest site only. No information found here must under any circumstances be used for medical purposes, diagnostically, therapeutically or otherwise. If you, or anybody close to you, is affected, or believe to be affected, by any condition mentioned here: see a doctor. Cerebral gigantism, cerebral gigantism in childhood, constitutional gigantism, gigantismus cerebralis, gigantismus constitutionalis, gigantismus idiopathicus, hypothalamic gigantism, macrostomia-mental retardation syndrome, mental retardation-overgrowth sequence, pituitary gigantism, prenatal gigantism with macrocephaly. A syndrome of excessive growth during the first 4 to 5 years of life, with cerebral gigantism and generalised large muscles in childhood, acromegalic features, and a nonprogressive cerebral disorder with nonprogressive mild mental retardation and defective coordination. After early childhood growth seems to approach normal, remaining, however, two standard deviations above means for chronological age. Birth weight and length greater than normal. Other principal features are dolicocephaly, macrocrania, hypertelorism, antimongoloid palpebral slant, high-arched palate, frontal bossing, mandibular prognathism, and precocious dentition. Occasionally, obesity, convulsions, abnormal dermatoglyphic pattern. Both sexes. Most cases are sporadic but some are transmitted as an autosomal dominant trait.
Neuroguide.com - Human Neurological Diseases Cerebral Palsy. Cerebral Palsy Information and Resource Links Cephalic Disorders. Cerebral Aneurysm. Cerebral Arteriosclerosis. Cerebral Atrophy. cerebral gigantism. Cerebral Palsy http://www.neuroguide.com/cgi-bin/pdistoc.pl?file=cerebral_palsy
Healthfinder® - Cerebral Gigantism Carefully selected government and nonprofit health information on cerebral gigantism. healthfinder® home page, healthfinder® your http://www.healthfinder.gov/Scripts/SearchContext.asp?topic=146
Healthfinder® - Cerebral Gigantism Carefully selected government and nonprofit health information on cerebral gigantism. home health library all topics C cerebral gigantism. http://www.healthfinder.gov/Scripts/SearchContext.asp?topic=146&refine=1
Extractions: Home About Links Index ... Editor's Choice document.write(code); Advertisement Endocrinology Growth Assorted Pages Delayed Growth Calculation of Growth Delay Growth Delay Onset Determination Achondroplasia ... Risser Sign Cerebral Gigantism Soto Syndrome Book Home Page Cardiovascular Medicine Dentistry Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Endocrinology Index Adrenal Disease General Dermatology Diabetes Mellitus Examination Ophthalmology Geriatric Medicine Growth Hematology and Oncology Hypoglycemia Laboratory Metabolism Neonatology Obesity Obstetrics Parathyroid Disease Pediatrics Pharmacology Pituitary Disease Prevention Radiology Nephrology Sex Sports Medicine Surgery Symptom Evaluation Thyroid Disease Page Growth Index Short Short Calculation Short Onset Short Achondroplasia Short Constitutional Short Familial Tall Tall Cerebral Gigantism Signs Tall Stature Prominent forehead Hypertelorism High arched palate Large irregular head Antimongoloid slant of palpebral fissures Mental retardation Advanced bone age Labs See Tall Stature Lab results are normal in this condition Search other websites for this topic Advertisement Please see the
Gigantism gigantism ( The Mosby Medical Encyclopedia)gigantism gigantism ( AAP General News (Australia))cerebral gigantism ( The Mosby Medical Encyclopedia)exophthalmosmacroglossia- gigantism http://www.infoplease.com/ce6/sci/A0820796.html
Extractions: gigantism gigantism (The Mosby Medical Encyclopedia) NSW: New discovery could lead to cure for dwarfism, gigantism (AAP General News (Australia)) ENVIRONMENT: NEW BUTTER FACES FEARS OF CANCER, GIGANTISM (Inter Press Service English News Wire) COMPARED TO ATLANTA, AUSSIES HAVE ADVANTAGE IN SECURITY ORGANIZERS OF 2000 OLYMPICS TRY TO AVOID TRAFFIC CONGESTION, GIGANTISM, COMMERICALISM OF `ENORMOUS' 1996 GAMES (Denver Rocky Mountain News) gigantism (The Hutchinson Dictionary of Science) cerebral gigantism (The Mosby Medical Encyclopedia) exophthalmos-macroglossia-gigantism syndrome (The Mosby Medical Encyclopedia) GRASS ROOTS FIGHT MEDIA GIGANTISM.(Editorial)(Column)
SOTOS SYNDROME (CEREBRAL GIGANTISM) Features Listed For SOTOS SYNDROME (cerebral gigantism). McKusick 117550. Advanced bone age/large epiphyses; Advanced tooth eruption http://www.hgmp.mrc.ac.uk/dhmhd-bin/hum-look-up?1613
Gigantism gigantism ( The Mosby Medical Encyclopedia)gigantism gigantism ( AAP General News (Australia))cerebral gigantism ( The Mosby Medical Encyclopedia)exophthalmosmacroglossia- gigantism http://www.infoplease.com/ce5/CE020807.html
Extractions: gigantism gigantism (The Mosby Medical Encyclopedia) NSW: New discovery could lead to cure for dwarfism, gigantism (AAP General News (Australia)) ENVIRONMENT: NEW BUTTER FACES FEARS OF CANCER, GIGANTISM (Inter Press Service English News Wire) COMPARED TO ATLANTA, AUSSIES HAVE ADVANTAGE IN SECURITY ORGANIZERS OF 2000 OLYMPICS TRY TO AVOID TRAFFIC CONGESTION, GIGANTISM, COMMERICALISM OF `ENORMOUS' 1996 GAMES (Denver Rocky Mountain News) gigantism (The Hutchinson Dictionary of Science) cerebral gigantism (The Mosby Medical Encyclopedia) exophthalmos-macroglossia-gigantism syndrome (The Mosby Medical Encyclopedia) GRASS ROOTS FIGHT MEDIA GIGANTISM.(Editorial)(Column)
Healthfinder® Cerebral Palsy Among Children This online brochure presents a synopsis of CPrelated surveillance and research activities. The brochure provides statistics on incidence and prevalence and discusses secondary conditions and help about healthfinder®. Cerebral Palsy Among Children Birth Defect. cerebral gigantism. Cerebral Palsy. Neuromuscular Diseases http://www.healthfinder.gov/docs/doc04850.htm
Extractions: health library just for you health care organizations search: help http://www.cdc.gov/ncbddd/factsheets/cp.pdf National Center on Birth Defects and Developmental Disabilities This online brochure presents a synopsis of CP-related surveillance and research activities. The brochure provides statistics on incidence and prevalence and discusses secondary conditions and resource materials. Birth Defect Cerebral Gigantism Cerebral Palsy Neuromuscular Diseases Research Surveillance and Data Systems accessibility freedom of information act privacy contact us ...
Cerebral Gigantism - General Practice Notebook cerebral gigantism. Sotos syndrome presents in childhood with developmental delay, high forehead, large hands and feet and tall for age. http://www.gpnotebook.co.uk/cache/349175833.htm
Cerebral Gigantism - General Practice Notebook cerebral gigantism. Medical search. Sotos syndrome presents in childhood with developmental delay, high forehead, large hands and feet and tall for age. http://www.gpnotebook.co.uk/medwebpage.cfm?ID=349175833
Extractions: (advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Pediatrics Endocrinology Last Updated: March 18, 2004 Rate this Article Email to a Colleague Synonyms and related keywords: growth hormone excess, GH excess, giantism, gigantosoma, giant, hypersomia, somatomegaly, acromegalia, endocrine system, pituitary gland, abnormal growth AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Melanie Shim, MD , Clinical Instructor, Department of Pediatrics, Division of Pediatric Endocrinology, Mattel Children's Hospital and University of California at Los Angeles Coauthor(s): Pinchas Cohen, MD , Director of Research and Training, Professor, Department of Pediatrics, Division of Endocrinology, Mattel Children's Hospital, University of California at Los Angeles Melanie Shim, MD, is a member of the following medical societies: American Diabetes Association , and Endocrine Society Editor(s): Phyllis Speiser, MD
Endotext.com - Pediatric Endocrinology, Gigantism Contributors. Search. Gigantism refers to a condition characterized by extreme physical size and stature. By definition, this originates during infancy, childhood or adolescence, while epiphyseal growth plates remain open. Sotos syndrome, also known as cerebral gigantism, was first described in 196493 http://www.endotext.com/pediatrics/pediatrics1b/pediatrics1b.htm
Extractions: I. INTRODUCTION Gigantism refers to a condition characterized by extreme physical size and stature. By definition, this originates during infancy, childhood or adolescence, while epiphyseal growth plates remain open. Although often used to specifically denote growth hormone excess, the term gigantism is also applied to a number of non-hormonally mediated overgrowth conditions in children. All forms of gigantism are extremely rare, and have in common a complex pathophysiologic origin and extraordinary clinical manifestations. Although many aspects of overgrowth disorders remain to be elucidated, insights into the molecular genetic basis of several forms of gigantism have contributed greatly to our understanding of specific mediators of growth and cellular function. Both growth hormone hypersecretion and overgrowth syndromes will be reviewed in this chapter. II. GROWTH HORMONE EXCESS . The major difference between these two conditions is that gigantism results from excessive GH production during the period of active growth, and acromegaly results from GH excess ensuing after epiphyseal fusion has occurred. A further distinction relates to the overall incidence of these disorders. While acromegaly is uncommon, occurring at an estimated worldwide annual rate of 2.8-4 cases per million
Extractions: National Organization for Rare Disorders Sotos Syndrome is a rare genetic disorder characterized by excessive growth that occurs prior to and after birth (prenatally and postnatally). At birth, affected infants have unusually increased body length that is abnormal in proportion to weight, which may also be above average; in addition, newborns typically demonstrate advanced bone growth, abnormally large hands and/or feet, and characteristic facial features. Abnormally rapid growth continues after birth until approximately four or five years of age, at which time growth may slow to a normal rate. Adult height usually exceeds the 50th percentile. Some affected individuals may reach excessive adult heights; males of 193 cm to 203 cm (6 feet 4 inches to 6 feet 8 inches) and females up to 188 cm (6 feet 2 inches) have been described.
Extractions: Web Directory: About com Guide Laura L. Jelliffe, Ph.D. Symptoms, diagnosis, and treatment of Soto's syndrome. Information on research, community outreach and support. MCW Healthlink An article about soto's syndrome with an explanation of what it is, the features, symptoms and the prognosis. Soto's Syndrome Also known as cerebral gigantism, an information sheet compiled by NINDS. Sotos Syndrome Support Association Online community for education of professionals and families and to exchange ideas, gather research, and help one another cope. Quarterly newsletters, reference library, annual meetings, and conferences are available to members and professionals.
Sotos Syndrome subdivision(s) covered by this report. Synonyms cerebral gigantism. Disorder Subdivisions None. General Discussion Sotos Syndrome is a rare http://my.webmd.com/hw/health_guide_atoz/nord271.asp
Index Disorder IV Familial Cerebellopontine Angle Tumor Cerebelloretinal Hemangioblastomatosis Cerebral Arachnoiditis cerebral gigantism Cerebral Malformations http://my.webmd.com/hw/index/index-topics-C.asp
Database Search Results Department of Health and Human Services.. Searched keywords for cerebral gigantism. Sotos Syndrome Support Association. NHIC Home Page http://www.health.gov/nhic/NHICScripts/Hitlist.cfm?Keyword=Cerebral Gigantism
