Central Pontine Myelinolysis central pontine myelinolysis,. Print this article, central pontine myelinolysis, Fig. 1. MR, T2weighted axial image of the posterior fossa. http://www.amershamhealth.com/medcyclopaedia/medical/Volume VI 1/CENTRAL PONTINE
Extractions: Amershamhealth.com Search for: Type a word or a phrase. All forms of the word are searchable. Browse entry words starting with: A B C D ... Other characters Central pontine myelinolysis, (also called osmotic demyelination), demyelinating disorder found in alcoholics or in association with many systemic disorders with electrolyte abnormalities. Because of the common association with rapidly corrected hyponatraemia, the term "osmotic demyelination syndrome" has been proposed. The symptoms of central pontine myelinolysis are quadriparesis, pseudobulbar palsy and changing levels of consciousness, including coma and death. Histologically, the area of myelin breakdown is sharply demarcated and displays extensive loss of oligodendrocytes, infiltration with foamy macrophages and reactive astrocytosis. At MR the lesion is characterized by T2 hyperintensity in a central pontine location ( Fig.1 ); gadolinium enhancement may sometimes be present. Extrapontine sites of myelinolysis in the basal ganglia and midbrain, and subcortical white matter may also occur. Many entities can be considered in the differential diagnosis, including ischaemia, multiple sclerosis, encephalitis, toxic exposures, radiation therapy effects and brain stem gliomas. When present, the key to the MRI diagnosis is the bilateral involvement of the deep and capsular white matter, often accompanied by abnormalities in the thalami and basal ganglia.
Myelinolysis, Central, Pontine Other characters, Myelinolysis, central, pontine,. Print this article, see central pontine myelinolysis. GS. The Encyclopaedia of Medical Imaging Volume VI1. http://www.amershamhealth.com/medcyclopaedia/medical/Volume VI 1/MYELINOLYSIS CE
Extractions: Dictionaries: General Computing Medical Legal Encyclopedia Word: Word Starts with Ends with Definition Central pontine myelinolysis is a neurologic disease caused by severe damage of the myelin sheath In neuroscience, myelin is an electrically insulating fatty layer that surrounds the axons of many neurons, especially those in the peripheral nervous system. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system. The main consequence of a myelin layer (or sheath ) is an increase in the speed at which impulses propagate along the myelinated fiber. Along unmyelinated fibers impulses move continuously as waves, but in myelinated fibers they hop (or "propagate by saltation"). When a fiber is severed, the myelin sheath provides a track along which regrowth can occur. Unmyelinated fibers do not regenerate.
Central Pontine Myelinolysis central pontine myelinolysis. toxic demyelination; rapid correction of hyponatremia. low density in central pons variable size; may http://chorus.rad.mcw.edu/doc/00066.html
Central Pontine Myelinolysis From Linkspider UK Health Directory central pontine myelinolysis by Linkspider UK, central pontine myelinolysis links and central pontine myelinolysis topics from our Health directory. http://linkspider.co.uk/Health/ConditionsandDiseases/NeurologicalDisorders/Brain
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Central Pontine Myelinolysis - General Practice Notebook central pontine myelinolysis. central pontine myelinolysis (CPM) is a rare demyelinating condition of the pons affecting long tract http://www.gpnotebook.co.uk/cache/-1583742920.htm
Central Pontine Myelinolysis - General Practice Notebook central pontine myelinolysis. Medical search. central pontine myelinolysis (CPM) is a rare demyelinating condition of the pons affecting http://www.gpnotebook.co.uk/medwebpage.cfm?ID=-1583742920
Central Pontine Myelinolysis CPM central pontine myelinolysis, central pontine myelinolysis in an alcoholic patient with an admitting serum sodium of 160 (normal up to 145). http://uscneurosurgery.com/glossary/c/cpm.htm
Extractions: Drkoop: Medical Encyclopedia - A definition of central pontine myelinolysis, including the causes, risks, prevention, symptoms, diagnosis, treatment, prognosis and complications. E-Medicine - Central Pontine Myelinolysis: An introduction, clinical features, differencials, work up, treatment and follow up.
Extractions: Back Back to main Health Information page Central nervous system Definition: Central pontine myelinolysis is a condition characterized by nerve damage caused by the destruction of the covering layer ( myelin sheath) of nerve cells in the brainstem (pons). Alternative Names: CPM Causes And Risk: The destruction of the myelin sheath that coats nerves inhibits impulse conduction within the cell and thus decreases its ability to communicate with other cells. The most common cause of central pontine myelinolysis is a rapid, drastic change in sodium levels in the body. Most commonly, this occurs when someone is being treated for low levels of sodium ( hyponatremia ) and the levels rise too fast, but it can occasionally occur when high levels of sodium in the body (hypernatremia) are corrected too quickly. This condition does not occur spontaneously; it is a complication of either treatment for other conditions or the other conditions themselves.
Central Pontine Myelinolysis Subject central pontine myelinolysis Topic Area Myelin Forum The Neurology and Neurosurgery Forum Question Posted By Ottilie on Saturday, March 04, 2000 http://www.medhelp.org/forums/neuro/messages/30435a.html
Extractions: Would like to know if any research is being done on this disease on the brain stem (pons). I have it plus it has caused down beat nystagmus which prevents me from driving. The psychological impact is terrible. I also would like to find someone with this disease. So far I have not. Answer Posted By: CCF Neuro[P] MD, RPS on Saturday, March 04, 2000 Central pontine myelinosis is usually results from changes in the osmolarity (electrolyte and protein concentration) in the brain versus the blood stream. The abnormal difference between the two causes the myelin surrounding the nerve processes to become unraveled. This inturn causes dysfunction of the nerves in this area. This is not a disease, but the result from an abnormality.
Central Pontine Myelinolysis Subject central pontine myelinolysis Topic Area Traumatic Brain Injury Forum The Neurology and Neurosurgery Forum Question Posted By gsoh on Monday http://www.medhelp.org/forums/neuro/messages/30819a.html
Extractions: She has improved from assisted standing to self-gait walking (500 meters) over 6 weeks. Able to stand up on her own from a few limited sitting positions. Her right hand is able to hold a small cup of water. Taking a deep breath to hold on is still a difficulty. Rollover on bed is still very difficult. The strongest part of the four limbs at right leg is still having difficulty for coordinated movement. I am obviously more interested to know any chances of speeding up the process of re-myelination before it is too late. I started reading about the myelin reformation. Unfortunately, I cannot find any resources that confirm positively the process in adult brain cells. Nor is there any authority to rule out the process or point to the timing of a brain damage like CPM or other brain disorders. I started giving her Omega-3 oil, colloidal form minerals, Vitamin B6, B12. I read about IgG that may act with adult Oligodendroglia for the re-myelination process. So I give her chewable tablets of colostrums which contained high concentration of Immunoglobulin G. All these, being health food supplements, in my mind, should have minimal side effects.
Central Pontine Myelinolysis- Medcohealth.com central pontine myelinolysis is a condition characterized by nerve damage caused by the destruction of the covering layer (myelin sheath) of nerve cells in the http://www.medcohealth.com/medco/consumer/ehealth/ehsarticle.jsp?topicID=HE:Dise
Singapore Medical Journal In a patient with a history of sodium replacement, this finding is in keeping with osmotic myelinolysis (or central pontine myelinolysis). http://www.sma.org.sg/smj/4101/articles/4101me1ans.htm
Extractions: C Y Chan, H S Lam, J R Jinkins IMAGE INTERPRETATION MR scans showede a 1 cm area of T2 hyperintensity in the central pontine region (Fig 1a) . In a patient with a history of sodium replacement, this finding is in keeping with osmotic myelinolysis (or central pontine myelinolysis). Multiple areas of T2 hyperintensity were seen in the basal ganglia and deep white matter (Fig 1b) , representing part of the same process. DIAGNOSIS Osmotic myelinolysis (central pontine myelinolysis) CLINICAL COURSE The patient did not improve clinically over the following months. She developed spastic tetraparesis, pseudobulbar palsy and horizontal nystagmus. Because of mutism, antidepressants were tried but they were not effective. She remained bed-ridden and ventilator-dependent. During her hospital stay, she developed several episodes of chest and urinary tract infection which were controlled with antibiotics. The patient finally died one year later due to multiple organ failure and sepsis. DISCUSSION Osmotic myelinolysis (OM) is a demyelinating disease that can develop following rapid correction of hyponatremia from any cause. It was originally described in chronic alcoholics. Other reported associations include malnourished status, renal failure, diabetes mellitus, and post-orthotopic liver transplantation
REFERENCES central pontine myelinolysis clinical and MRI correlates. Postgrad Med J 1995; 7143042. Reversal of MR findings of central pontine myelinolysis. http://www.sma.org.sg/smj/4101/references/4101me1ref.htm
Extractions: REFERENCES Ho VB, Fitz CR, Yoder CC, Geyer CA. Resolving MR features in osmotic myelinolysis (central pontine and extrapontine myelinolysis). AJNR 1993; 14:163-7. Martin PJ, Young CA. Central pontine myelinolysis: clinical and MRI correlates. Postgrad Med J 1995; 71:430-42. Laaureno R, Karp BI. Myelinolysis after correction of hyponatremia. Ann Intern Med 1997; 126:57-62. McGraw P, Edwards-Brown MK. Reversal of MR findings of central pontine myelinolysis. J Comput Assist Tomogr 1998; 22:989-91. Gregorio L, Sutton CL, Lee DA. Central pontine myelinolysis in a previously healthy 4-year-old child with acute rotavirus gastroenteritis. Pediatrics 1997; 99:738-43. Karp BI, Laureno R. Pontine and extrapontine myelinolysis: a neurologic disorder following rapid correction of hyponatremia. Medicine (Baltimore) 1993; 72:359-73. Korogi Y, Takahashi M, Shinzato J, Sakamoto Y, Mitsuzaki K, Hirai T, et al. MR findings in two presumed cases of mild central pontine myelinolysis. AJNR 1993; 14:651-4. Gocht A, Colmant HJ. Central pontine and extrapontine myelinolysis: a report of 58 cases. Clin Neuropathol 1987; 6:262-70.
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Central Pontine Myelinolysis Directory, Home Health Conditions and Diseases Neurological Disorders Brain Diseases Metabolic central pontine myelinolysis (3) See Also http://www.thenewhealthfind.com/Health/ConditionsandDiseases/NeurologicalDisorde
Extractions: Acute Renal Failure Atrophy Central Pontine Myelinolysis Coagulopathy ... About H.E.R. Central Pontine Myelinolysis Nerve damage caused by the destruction of the covering layer (myelin sheath) of nerve cells in the brainstem (pons). For more info, see our Neurological Conditions page. Offsite Research: Magnetic resonance imaging detection of a lesion compatible with central pontine myelinolysis in a pregnant patient with recurrent vomiting and confusion.
Extractions: Acute Renal Failure Atrophy Central Pontine Myelinolysis Coagulopathy ... About H.E.R. Central Pontine Myelinolysis Nerve damage caused by the destruction of the covering layer (myelin sheath) of nerve cells in the brainstem (pons). For more info, see our Neurological Conditions page. Offsite Research: Magnetic resonance imaging detection of a lesion compatible with central pontine myelinolysis in a pregnant patient with recurrent vomiting and confusion.
Central Pontine Myelinolysis central pontine myelinolysis. Alternative Names The most common cause of central pontine myelinolysis is a rapid, drastic change in sodium levels in the body. http://lebonheur.adam.com/pages/content.asp?genId=000775&proj=1&lang=en
