Extractions: (advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Neurology Neurotoxicology Last Updated: March 12, 2001 Rate this Article Email to a Colleague Synonyms and related keywords: osmotic myelinolysis AUTHOR INFORMATION Section 1 of 9 Author Information Introduction Clinical Differentials ... Bibliography Author: Christopher C Luzzio, MD , Clinical Assistant Professor, Department of Neurology, University of Wisconsin at Madison Christopher C Luzzio, MD, is a member of the following medical societies: American Academy of Neurology Editor(s): Howard A Crystal, MD , Professor, Departments of Neurology and Pathology, State University of New York Downstate; Francisco Talavera, PharmD, PhD , Senior Pharmacy Editor, Pharmacy, eMedicine; Richard J Caselli, MD , Chairperson, Department of Neurology, Professor, Department of Neurology, Mayo Clinic of Scottsdale; Selim R Benbadis, MD
Central Pontine Myelinolysis A definition of central pontine myelinolysis, including the causes, risks, prevention, symptoms, diagnosis, treatment, prognosis and complications. http://www.drkoop.com/ency/article/000775.htm
Extractions: Causes, incidence, and risk factors: The destruction of the myelin sheath that coats nerves inhibits impulse conduction within the cell and thus decreases its ability to communicate with other cells. The most common cause of central pontine myelinolysis is a rapid, drastic change in sodium levels in the body. Most commonly, this occurs when someone is being treated for low levels of sodium ( hyponatremia ) and the levels rise too fast, but it can occasionally occur when high levels of sodium in the body (hypernatremia) are corrected too quickly. This condition does not occur spontaneously; it is a complication of either treatment for other conditions or the other conditions themselves.
MedlinePlus Medical Encyclopedia: Central Pontine Myelinolysis central pontine myelinolysis is a condition characterized by nerve damage caused by the destruction of most common cause of central pontine myelinolysis is a rapid, drastic change http://www.nlm.nih.gov/medlineplus/ency/article/000775.htm
Extractions: @import url(http://www.nlm.nih.gov/medlineplus/images/advanced.css); Skip navigation Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Contents of this page: Central nervous system Alternative names Return to top CPM Definition Return to top Central pontine myelinolysis is a condition characterized by nerve damage caused by the destruction of the covering layer ( myelin sheath) of nerve cells in the brainstem (pons). Causes, incidence, and risk factors Return to top The destruction of the myelin sheath that coats nerves inhibits impulse conduction within the cell and thus decreases its ability to communicate with other cells. The most common cause of central pontine myelinolysis is a rapid, drastic change in sodium levels in the body. Most commonly, this occurs when someone is being treated for low levels of sodium ( hyponatremia ) and the levels rise too fast, but it can occasionally occur when high levels of sodium in the body (hypernatremia) are corrected too quickly. This condition does not occur spontaneously; it is a complication of either treatment for other conditions or the other conditions themselves.
Central Pontine Myelinolysis Was First Described By Adams Et Al... central pontine myelinolysis Following Hemodialysis. Author Dr R Dewan, Dr Rahul Rai, Dr Praveen Gupta, Dr Rahul Anand, Dr Pankaj Mehta, Dr Sameer Gulati http://www.indegene.com/Neu/ClinRound/indNeuCase10.html
Extractions: Hospital: Depatment of Medicine, Maulana Azad Medical College, New Delhi Introduction Central pontine myelinolysis was first described by Adams et al in 1959 during the course of studying the neuropathology of alcoholism. The lesion was localized to the central rostral part of the pons and consisted of a sharply outlined focus of myelin destruction. Quadriplegia and pseudobulbar palsy were the main clinical findings. CPM was usually a postmortem diagnosis till the advent of the CT and the MRI. We report this interesting case of a young lady who developed CPM following hemodialysis. Case Report A young 26-year-old lady, a diagnosed case of Hypertension with MPGN with Chronic Renal Failure, was admitted with complaints of sudden onset loss of consciousness. The patient had developed altered sensorium 4 days before presentation, for which she was taken to a private nursing home and was hemodialysed twice. Following dialysis she developed drooping of the right eyelid and progressive paraparesis. Following this the patient developed loss of consciousness, when she was brought to our hospital. There was no other significant history. On examination the patient was unconscious, not responding to painful stimulus and a blood pressure of 180/130. The general physical examination showed pallor and facial puffiness but no icterus, clubbing or lymphadenopathy. Chest, CVS and per abdomen examination was normal. CNS examination revealed deep comatose state, a right third nerve palsy, paraparesis, which later progressed to quadriparesis, with bilateral up-going plantars.
Central Pontine Myelinolysis central pontine myelinolysis is a condition characterized by nerve damage caused by the destruction of most common cause of central pontine myelinolysis is a rapid, drastic change http://www.pennhealth.com/ency/article/000775.htm
Extractions: Search Encyclopedia: List of Topics Print This Page  Cognitive Neurology Central nervous system Definition: Central pontine myelinolysis is a condition characterized by nerve damage caused by the destruction of the covering layer ( myelin sheath) of nerve cells in the brainstem (pons). Alternative Names: CPM Causes, incidence, and risk factors: The destruction of the myelin sheath that coats nerves inhibits impulse conduction within the cell and thus decreases its ability to communicate with other cells. The most common cause of central pontine myelinolysis is a rapid, drastic change in sodium levels in the body. Most commonly, this occurs when someone is being treated for low levels of sodium ( hyponatremia ) and the levels rise too fast, but it can occasionally occur when high levels of sodium in the body (hypernatremia) are corrected too quickly. This condition does not occur spontaneously; it is a complication of either treatment for other conditions or the other conditions themselves. Risks include hyponatremia from any cause.
Extractions: (advertisement) Synonyms, Key Words, and Related Terms: osmotic myelinolysis Background: Adams et al described central pontine myelinolysis (CPM) as a unique clinical entity. They published their findings in 1958, observing that patients who suffered from alcoholism or malnutrition developed spastic quadriplegia, pseudobulbar palsy, and varying degrees of encephalopathy or coma from acute, noninflammatory demyelination that centered within the basis pontis. Contemporary physicians recognize that CPM occurs inconsistently as a complication of severe and prolonged hyponatremia, particularly when corrected too rapidly. Standard of care requires judicious treatment of electrolyte disturbances to reduce the incidence of osmotic myelinolysis. Pathophysiology: CPM is concentrated, frequently symmetric, noninflammatory demyelination within the central basis pontis. In at least 10% of patients with CPM, demyelination also occurs in extrapontine regions, including the mid brain, thalamus, basal nuclei, and cerebellum. The exact mechanism that strips the myelin sheath is unknown. One theory proposes that in regions of compact interdigitation of white and gray matter, cellular edema, which is caused by fluctuating osmotic forces, results in compression of fiber tracts and induces demyelination. Prolonged hyponatremia followed by rapid sodium correction results in edema. During the period of hyponatremia, the concentration of intracellular charged protein moieties is altered; reversal cannot parallel a rapid correction of electrolyte status. The term "osmotic myelinolysis" is more appropriate than "central pontine myelinolysis" for demyelination occurring in extrapontine regions after the correction of hyponatremia.
Pediatric Database A definition of central pontine myelinolysis, the epidemiology, pathogenesis, clinical features, investigations and management. http://www.icondata.com/health/pedbase/files/CENTRALP.HTM
Medical Encyclopedia: Central Pontine Myelinolysis (Print Version) Medical Encyclopedia central pontine myelinolysis. There is no known cure for central pontine myelinolysis and treatment is focused on relieving symptoms. http://www.nlm.nih.gov/medlineplus/print/ency/article/000775.htm
Extractions: To close this window, click on the "x" in the upper right hand corner of the window. URL of this page: http://www.nlm.nih.gov/medlineplus/ency/article/000775.htm Alternative names CPM Definition Central pontine myelinolysis is a condition characterized by nerve damage caused by the destruction of the covering layer (myelin sheath) of nerve cells in the brainstem (pons). Causes, incidence, and risk factors The destruction of the myelin sheath that coats nerves inhibits impulse conduction within the cell and thus decreases its ability to communicate with other cells. The most common cause of central pontine myelinolysis is a rapid, drastic change in sodium levels in the body. Most commonly, this occurs when someone is being treated for low levels of sodium (hyponatremia) and the levels rise too fast, but it can occasionally occur when high levels of sodium in the body (hypernatremia) are corrected too quickly. This condition does not occur spontaneously; it is a complication of either treatment for other conditions or the other conditions themselves.
NeuroGate.com Search results for "central pontine myelinolysis" Cardioguide Matches 1 1 of 1. demyelinating disease - http://www.neurogate.com/neuro/result.php3?search=Central Pontine Myelinolysis&a
Central Pontine Myelinolysis central pontine myelinolysis. Alternative Names CPM. There is no known cure for central pontine myelinolysis and treatment is focused on relieving symptoms. http://www.drkoop.com/ency/article/000775trt.htm
Myelinolysis, Central Pontine Myelinolysis, Central Pontine Medical.WebEnds.com Myelinolysis, Central Pontine. central pontine myelinolysis; Extrapontine Myelinolysis; Extrapontine Central Pontine; Pontine Myelinolysis http://medical.webends.com/index.php?id=15150
Extractions: Web Directory: Drkoop: Medical Encyclopedia: Central Pontine Myelinolysis A definition of central pontine myelinolysis, including the causes, risks, prevention, symptoms, diagnosis, treatment, prognosis and complications. E-Medicine Central Pontine Myelinolysis: An introduction, clinical features, differencials, work up, treatment and follow up.
Central Pontine Myelinolysis Medical Encyclopdia article about central pontine myelinolysis central pontine myelinolysis. A Medical Encyclopedia Article provided by the University of with information on over 4000 medical http://www.umm.edu/medical-terms/02060.htm
Central Pontine Myelinolysis Following Hemodialysis - Images Top. Email this Article to a Colleague, Search, Participate in Discussions. Members Agreement, Privacy Policy, Disclaimer, Copyright 2000 of Indegene Lifesystems Pvt. http://www.indegene.com/Neu/ClinRound/indNeuCase10child.html
Central Pontine Myelinolysis central pontine myelinolysis. toxic demyelination. rapid correction of hyponatremia. low density in central pons. variable size. may have paired, rounded lesions http://chorus.rad.mcw.edu/to-go/00066.html
AllRefer Health - Central Pontine Myelinolysis (CPM) central pontine myelinolysis (CPM) information center covers causes, prevention, symptoms, diagnosis, treatment, incidence, risk factors, signs, tests, support http://health.allrefer.com/health/central-pontine-myelinolysis-info.html
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Extractions: AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia
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Extractions: Metabolic Disorders Marchiafava-Bignami disease Case 1 Case 2 Related Internet Resources MRI Images - University of Florida, US Central pontine myelinolysis Case 1 Related Internet Resources Myelinolysis after Correction of Hyponatremia, Annals of Internal Medicine, 1997, 126:57-62 Other Resources var site="sm5hegeduskdote" Last modified: February 17, 2001
Demyelinating Diseases - Internet Handbook Of Neurology demyelinating diseases, multiple sclerosis, leukodystrophy, central pontine myelinolysis, progressive multifocal leukoencephalopathy. http://www.neuropat.dote.hu/myelin.htm
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