41. Neurology -- Abstracts: Wilkinson Et Al. 61 (4): 479 Donepezil in vascular dementia. Objective To evaluate the efficacy and tolerability of donepezil in patients with vascular dementia (VaD). http://www.neurology.org/cgi/content/abstract/61/4/479

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: Figures Only for this Article Full Text of this Article PDF Version of this Article Citation Map ... Email this article to a friend Correspondence: Submit a response to this article Similar articles found in: Neurology Online PubMed PubMed Citation This Article has been cited by: other online articles Search PubMed for articles by: Wilkinson, D. Pratt, R.D. Alert me when: new articles cite this article Download to Citation Manager Collections under which this article appears: All Clinical trials Clinical trials Randomized controlled (CONSORT agreement) All Cognitive Disorders/Dementia Vascular dementia Neurology American Academy of Neurology Donepezil in vascular dementia A randomized, placebo-controlled study D. Wilkinson, MBChB MRCGP, FRCPsych R. Doody, MD PhD R. Helme, MBBS PhD, FRACP, FFPMANZCA K. Taubman, MBBS FRACP J. Mintzer, MD A. Kertesz, MD and R.D. Pratt, MD the Donepezil 308 Study Group* Address correspondence and reprint requests to Dr. David Wilkinson, Memory Assessment and Research Centre, Moorgreen Hospital, Southampton SO30 3JB, UK; e-mail: david.wilkinson@wht.nhs.uk

42. NINDS - AIREN Criteria For Vascular Dementia | Internet Stroke Center NINDS AIREN criteria for the diagnosis of vascular dementia. I. The criteria for the clinical diagnosis of probable vascular dementia http://www.strokecenter.org/trials/scales/ninds-airen.html

Health Professionals Clinical Trials About Home Trials Directories Complete List Ongoing Trials Acute Stroke Trials Hemorrhage Trials ... Recovery Trials Interventions Drugs - By Name Drugs - By Category Procedures Recovery Therapies Assessment Scales Specific Stroke Scales Stroke Scale Links Stroke Scales Overview Stroke Trial Links Government Sites Independent Sites Recent Updates Update List ... Send Feedback Search for Trials By Trial Name By Intervention NINDS - AIREN criteria for the diagnosis of vascular dementia I. The criteria for the clinical diagnosis of probable vascular dementia include all of the following: Dementia defined by cognitive decline from a previously higher level of functioning and manifested by impairment of memory and of two or more cognitive domains (orientation, attention, language, visuospatial functions, executive functions, motor control, and praxis), preferable established by clinical examination and documented by neuropsychological testing; deficits should be severe enough to interfere with activities of daily living not due to physical effects of stroke alone.

43. DSM IV Criteria For Vascular Dementia | Internet Stroke Center DSMIV criteria for the diagnosis of vascular dementia. A. The development of multiple cognitive deficits manifested by both Memory http://www.strokecenter.org/trials/scales/dsm-IV.html

Health Professionals Clinical Trials About Home Trials Directories Complete List Ongoing Trials Acute Stroke Trials Hemorrhage Trials ... Recovery Trials Interventions Drugs - By Name Drugs - By Category Procedures Recovery Therapies Assessment Scales Specific Stroke Scales Stroke Scale Links Stroke Scales Overview Stroke Trial Links Government Sites Independent Sites Recent Updates Update List ... Send Feedback Search for Trials By Trial Name By Intervention DSM-IV criteria for the diagnosis of vascular dementia A. The development of multiple cognitive deficits manifested by both: Memory impairment (impaired ability to learn new information or to recall previously learned information) One or more of the following cognitive disturbances: (a) aphasia (language disturbance) (b) apraxia (impaired ability to carry out motor activities depite intact motor function) (c) agnosia (failure to recognize or identify objects despite intact sensory function)

44. Vascular Dementia - Medical Dictionary Definitions Of Popular Medical Terms MedicineNet Home MedTerms medical dictionary AZ List vascular dementia. Advanced Search. vascular dementia Index. http://www.medterms.com/script/main/art.asp?articlekey=21883

45. Vol 5, No.2: Alzheimers Disease And Vascular Dementia: Prof.A.D.Korczyn Alzheimer’s disease and vascular dementia. Professor vascular dementia and AD were both described approximately a century ago. Alois http://www.alzheimer-insights.com/insights/vol5no2/vol5no2a.htm

Professor Amos D. Korczyn, The term vascular dementia is now used to encompass several pathologically different and clinically distinguishable syndromes et al . [1] to describe dementia associated with multiple cerebrovascular occlusions. With improved imaging technology it became clear that vascular dementia represented a wider entity than MID and the Hachinski Ischemic Scale has now been reassessed [2]. In particular, Magnetic Resonance Imaging (MRI) revealed the presence of diffuse white matter lesions, presumably due to ischemic changes, in many demented patients. Thus, vascular damage can occur through various mechanisms ( Table 1 ). The term vascular dementia is now used to encompass several pathologically different and clinically distinguishable syndromes ( Table 2 Table 1. Mechanism of vascular damage. Hemorrhage Ischemia Thrombosis Vasospasm Low perfusion Differentiating AD from vascular dementia Table 2. Vascular dementia syndromes. MID Lacunar states (multiple small infarcts in the subcortical part of the brain) Binswanger’s disease (neuropathological findings include severe white matter destruction) Genetic forms (e.g. cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy [CADASIL])

46. Vascular Dementia WWW.NURSES.INFO. vascular dementia. vascular dementia. Alzheimer s Society Information Sheet What is vascular dementia? - What is vascular dementia? http://www.nurses.info/mental_health_dementia_vascular.htm

WWW.NURSES.INFO Vascular Dementia Home Contents Search Who are we? ... Sponsorship Vascular Dementia About Vascular Dementia (Multi-Infarct Dementia) - Vascular Dementia (MID Multi-infarct dementia) is caused by a series of small strokes which lead to loss of intellectual functioning. A lzheimer's Society Information Sheet - What is vascular dementia? What is vascular dementia? Download PDF file. Vascular dementia affects around a quarter of people with dementia in the UK. BehaveNet® Clinical Capsule™: DSM-IV: Vascular Dementia - When there is evidence that Dementia is caused by cardiovascular disease this diagnosis may apply. Computed imaging studies of the brain, such as CT (computed tomography) and MRI (magnetic resonance imaging), can usually detect evidence of vascular lesions. Dementias - Vascular Dementia - Multi-Infarct Dementia - Dementia is the loss of a person's cognitive, or intellectual, function. those conscious mental tasks that we perform every waking second of every day, from remembering our name to performing complicated mathematical calculations. Memory is one of the most essential cognitive functions, and it is the often the first and most crucial one that dementia impairs. PsychNet.UK. eMedicine - Vascular Dementia Vascular Dementia - Vascular dementia is the second most common form of dementia after Alzheimer disease (AD).

47. Memory Pharmaceuticals vascular dementia. vascular dementia is the second leading cause of dementia Multi Infarct Dementia TIA/Stroke/TBI Arteriosclerosis. http://www.memorypharma.com/market_vasculardementia.html

Home Contact Us Site Index Market Psychiatric Indications Age Associated Cognitive Decline Vascular Dementia Mild Cognitive Impairment Alzheimer's Market Opportunity: Over 180 million People Worldwide Vascular Dementia Vascular Dementia is the second leading cause of dementia Multi Infarct Dementia TIA/Stroke/TBI Arteriosclerosis Changes in the brain’s blood supply may result in the death of some brain tissue (neurons). The initiating event may be a single stroke (brain attack); a number of small strokes; a temporary decrease in brain blood flow transient ischemic attack (TIA); a traumatic brain injury (TBI) or the slow clogging of the arteries in the brain (arteriosclerosis). The location in the brain where the decreased blood flow occurs will determine the seriousness of the impact on cognition and type of symptoms that arise. Symptoms that begin suddenly may be a sign of this kind of dementia. People with vascular dementia may show signs of improvement or remain stable for long periods of time, then quickly develop new symptoms if more damage occurs. In many people with vascular dementia, high blood pressure is the root cause of the problem. Home About Us Market Pipeline ... Site Index © Memory Pharmaceuticals 2004

48. Memory Pharmaceuticals vascular dementia. vascular dementia is the second most common form of dementia after Alzheimer disease (AD) and accounts for up to a third of all dementias. http://www.memorypharma.com/p_1003_vasculardementia.html

Home Contact Us Site Index Pipeline MEM 1003 Alzheimer's Disease Mild Cognitive Impairment Vascular Dementia MEM 1414 PDE4 Inhibitors Nicotinic Alpha-7 Vascular Dementia Disease Information Causes Vascular dementia can be caused in several different ways. Most commonly there is blockage of small blood vessels (arteries) deep within the brain. When any part of the body is deprived of blood, which carries oxygen and nutrients, it dies - this is called an infarct or ischemia. When brain tissue dies it is also called necrosis. Blockages may be caused by build up of plaque on the inside of the arterial wall or by clots which have broken off, jamming a smaller tributary upstream. Clots can also result from abnormal heart rhythms, or other heart pathology, or can form on the inside of the major carotid arteries that run up the side of the neck and supply the brain. Rarer causes of vascular dementia are associated with auto-immune inflammatory diseases of the arteries such as systemic lupus erythermotsis (SLE or lupus) and temporal arteritis. Both of these can be treated with cortisone type drugs or other drugs to suppress the immune system. Types of Vascular Dementia Vascular dementia is due to impaired blood supply to the brain and can be divided into different types depending on the nature of the vascular disease.

49. Wordbank On The Mental Health Foundation Website A B C D E F G H I J K L M N O P Q R S T U V W X Y Z. vascular dementia. Also known as multiinfarct dementia. Valium. vascular dementia. Venlafaxine. http://www.mentalhealth.org.uk/wordbank.cfm?wordid=257&wbletter=V

50. Life Enhancement:: Galantamine Combats Alzheimer's And Vascular Dementia - Nov. A Review of the Studies Galantamine Combats Alzheimer s and vascular dementia The evidence for this natural herbal product s efficacy is overwhelming By Will http://www.life-enhancement.com/article_template.asp?ID=731

51. Life Enhancement:: Galantamine Improves Both Alzheimer's And Vascular Dementia - Galantamine Boosts Brain Acetylcholine Galantamine Improves Both Alzheimer s and vascular dementia Dual mode of action of this natural supplement accounts for http://www.life-enhancement.com/article_template.asp?ID=680

52. Alzheimer's Association-Greater Illinois Chapter: Vascular Dementia-Complex Path vascular dementia Complex Pathology, Confusing Symptoms. A lthough the average brain weighs only three pounds—accounting for just http://www.alzheimers-illinois.org/articles/vascular.html

Vascular Dementia: Complex Pathology, Confusing Symptoms A lthough the average brain weighs only three pounds—accounting for just 2 percent of the weight of a 150-pound person—it consumes 20 percent of the body’s oxygen and receives 20 percent of the body’s blood supply. Events that interfere with the brain’s blood supply pose a serious threat—its cells can survive without oxygen for only three to five minutes. When brain cells die, their death disrupts the mental or physical function controlled by the area where the damage occurs. Evolving Ideas about a Complex Disorder Medical thinking about vascular dementia has changed considerably over the past few decades. At one time, doctors attributed almost all mental impairment associated with old age to "hardening of the arteries" in the brain. As scientists gained deeper understanding of other dementing illnesses, Alzheimer’s gradually earned recognition as the most common dementia, and vascular dementia was considered the second most frequent. Experts now acknowledge that neither the frequency nor the characteristics of vascular dementia are well understood. Several professional bodies have developed different sets of criteria for diagnosing the disorder, making it difficult to estimate its frequency with any precision. Estimates found in recent scientific literature indicate that vascular dementia accounts for anywhere from one-tenth to one-third of dementia cases

53. Multi-infact Dementia: European Description F01 vascular dementia. Vascular (formerly arteriosclerotic suggesting Alzheimer s disease. to top. F01.1 vascular dementia Of Acute Onset. http://www.mentalhealth.com/icd/p22-or02.html

Multi-infact Dementia European Description The ICD-10 Classification of Mental and Behavioural Disorders World Health Organization, Geneva, 1992 Contents F01 Vascular Dementia F01.1 Vascular Dementia Of Acute Onset F01.1 Multi-Infarct Dementia F01.2 Subcortical Vascular Dementia ... F01.3 Mixed Cortical And Subcortical Vascular Dementia F01 Vascular Dementia Vascular (formerly arteriosclerotic) dementia, which includes multi-infarct dementia, is distinguished from dementia in Alzheimer's disease by its history of onset, clinical features, and subsequent course. Typically, there is a history of transient ischaemic attacks with brief impairment of consciousness, fleeting pareses, or visual loss. The dementia may also follow a succession of acute cerebrovascular accidents or, less commonly, a single major stroke. Some impairment of memory and thinking then becomes apparent. Onset, which is usually in later life, can be abrupt, following one particular ischaemic episode, or there may be more gradual emergence. The dementia is usually the result of infarction of the brain due to vascular diseases, including hypertensive cerebrovascular disease. The infarcts are usually small but cumulative in their effect. Diagnostic Guidelines The diagnosis presupposes the presence of a dementia as described above. Impairment of cognitive function is commonly uneven, so that there may be memory loss, intellectual impairment, and focal neurological signs. Insight and judgement may be relatively well preserved. An abrupt onset or a stepwise deterioration, as well as the presence of focal neurological signs and symptoms, increases the probability of the diagnosis; in some cases, confirmation can be provided only by computerized axial tomography or, ultimately, neuropathological examination.

54. Dementia: Update For The Practitioner Recognition of vascular dementia, Dementia with Lewy Bodies, and Frontotemporal Dementia Lawrence S. Honig, MD, Ph.D. vascular dementia. http://ci.columbia.edu/c1182/web/sect_5/c1182_s5_1.html

Introduction Diagnosis of Mild Cognitive Impairment and Alzheimer's Disease Karen L. Bell, M.D. Treatment Strategies for Dementia and Mild Cognitive Impairment Mary Sano, Ph.D. Treatment of Depression, Agitation, and Psychosis in Dementia Davangere P. Devanand, M.D. Recognition of Vascular Dementia, Dementia with Lewy Bodies, and Frontotemporal Dementia Lawrence S. Honig, M.D., Ph.D. Categorization of Dementias Prevalence of Non-Alzheimer Dementias The Spectrum of Lewy-Body Disease Frontotemporal Dementia ... Neuropsychology of Mild Cognitive Impairment, Alzheimer's Disease, Dementia with Lewy Bodies, and Frontotemporal Dementia Penne Sims, Ph.D. Neuroimaging in Dementia Scott A. Small, M.D. Genetics of Neurodegenerative Disease: Alzheimer's Disease, Frontotemporal Dementia Jennifer Williamson-Catania, M.S. Legal and Ethical Issues for Patients with Dementia Daniel G. Fish, Esq. Posttest Accreditation Reference List Acknowledgements Recognition of Vascular Dementia, Dementia with Lewy Bodies, and Frontotemporal Dementia Lawrence S. Honig, M.D., Ph.D.

55. Multi-Infarct Dementia Fact Sheet - Alzheimer's Disease Education & Referral Cen The second most common cause of dementia in older adults is vascular dementia, which affects the blood vessels in the brain. What is Alzheimer’s disease? http://www.alzheimers.org/pubs/mid.htm

ADEAR A Service of the National Institute on Aging Home About Us Site Map ... Help Viewing Site Alzheimer's Disease General Info Causes Symptoms Diagnosis ... Treatment Caregiving Home/Family Professional Health Info News Clinical Trials AD Research Centers Publications Browse/Search Newsletter Resources Literature Search (CHID) Media Room Conference Calendar Multi-Infarct Dementia Fact Sheet Contents Introduction Symptoms Diagnosis Treatment ... For More Information Introduction Serious forgetfulness, mood swings, and other behavioral changes are not a normal part of aging. They may be caused by poor diet, lack of sleep, or too many medicines, for example. Feelings of loneliness, boredom, or depression also can cause forgetfulness. These problems are serious and should be treated. Often they can be reversed. Sometimes, however, mental changes are caused by diseases that permanently damage brain cells. The term dementia describes a medical condition that is caused by changes in the normal activity of very sensitive brain cells. These changes in the way the brain works can affect memory, speech, and the ability to carry out daily activities. Multi-infarct dementia is the most common form of vascular dementia, and accounts for 10-20% of all cases of progressive, or gradually worsening, dementia. It usually affects people between the ages of 60-75, and is more likely to occur in men than women.

56. Vascular Dementia vascular dementia AND STROKE. A common complication resulting dementia in the elderly. ((Stroke. 2004;3510101017) . What is vascular dementia? http://www.strokesurvivors.ca/vasucular_dementia.htm

Home Contact and About Us the web strokesurvivors VASCULAR DEMENTIA AND STROKE A common complication resulting from stroke is loss of cognitive function, or intellectual abilities, often called vascular dementia. "Stroke and dementia increase exponentially with aging of the population. Less well known is their interplay,whereby stroke may result in vascular cognitive impairment (VCI) and vascular dementia (VaD), but conversely brain ischemia may worsen the cognitive effects of Alzheimer disease (AD) pathology. Post stroke dementia occurs in up to one third of patients with clinically eloquent ischemic stroke after age 65 years. Moreover, MRI-documented silent brain infarcts more than double the risk of dementia in the elderly. In addition, in these age groups VCI with no dementia (VCIND) is also common. With increasing longevity, the damaging effects of cerebrovascular disease (CVD) and heart disease on cognition may become one of themain causes of dementia in the elderly. ((Stroke. 2004;35:1010-1017)" What is Vascular Dementia?

57. ISSSAT Memantine Promising For Patients With Vascular Dementia ISSSAT Memantine Promising For Patients With vascular dementia FRANKFURT/MAIN, GERMANY April 11, 2000 Memantine, a drug for which applications have been http://www.pslgroup.com/dg/195c52.htm

58. AAN Galantamine Confers Benefits In Patients With Pure Vascular Increase Maintain Decrease. View Results. AAN Galantamine Confers Benefits in Patients With Pure vascular dementia By Jill Stein http://www.pslgroup.com/dg/243f26.htm

59. Vascular Dementia Health Search Engine, vascular dementia, vitacost.com Physician s Guide - Vitamin B rank 1000 both. This vascular dementia. Site http://www.thenewhealthfind.com/health/vascular dementia

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60. Alzheimers Australia You are here I have Dementia Types of dementia vascular dementia. vascular dementia AIDS What is vascular dementia? Are http://www.alzheimers.org.au/content.cfm?infopageid=440

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