81. Welcome To Ovid UCSF Hemostasis and thrombosis Center Main MenuOur Mission, Our Mission. Research, Research. Information for Clinics, Information for Clinics. Medications, Medications. Patient Information, http://gateway.ovid.com/ovidweb.cgi?T=JS&MODE=ovid&PAGE=toc&D=ovft&AN=00043605-0

82. Thrombosis killed by it. A better name is travellers thrombosis though the correct name is deepvein thrombosis or DVT. It s caused by http://cbc.ca/news/indepth/background/thrombosis.html

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83. Discovery Health Deep Venous Thrombosis Deep venous thrombosis, also called DVT, refers to a blood clot that has formed in one of the large veins far below the skin. http://health.discovery.com/diseasesandcond/encyclopedia/590.html

84. Economy Class Syndrome - DVT In The Air - Explained By A UK Expert Information about economy class syndrome and deep vein thrombosis (DVT) including precautions for air travel. http://www.economy-class.co.uk

Economy class syndrome, deep vein thrombosis (DVT), air travel, travel, advice and precautions. Click on picture to enter site

85. Thrombosis - Wikipedia, The Free Encyclopedia thrombosis. From Wikipedia, the free encyclopedia. thrombosis is the formation of a clot or thrombus inside a blood vessel, obstructing the flow of blood. http://en.wikipedia.org/wiki/Thrombosis

Thrombosis From Wikipedia, the free encyclopedia. Thrombosis is the formation of a clot or thrombus inside a blood vessel , obstructing the flow of blood through the circulatory system Table of contents 1 Causes 2 Types/classification 3 Embolisation 4 See also ... edit Causes Classically, thrombosis is caused by abnormalities in one or more of the following ( Virchow 's triad): The composition of the blood Quality of the vessel wall Nature of the blood flow The formation of a thrombus is usually caused by an injury to the vessel's wall, either by trauma or infection, and by the slowing or stagnation of blood flow past the point of injury. Occasionally, abnormalities in coagulation are to blame. Intravascular coagulation follows, forming a structureless mass of red blood cells leukocytes , and fibrin edit Types/classification There are two distinct forms of thrombosis: venous thrombosis and arterial thrombosis edit Embolisation If a bacterial infection is present at the site of thrombosis, the thrombus may break down, spreading particles of infected material throughout the circulatory system pyemia septic embolus ) and setting up metastatic abscesses wherever they come to rest. Without an infection, the thrombus may become detached and enter circulation as an

86. Deep Leg Vein Thrombosis Treatment of deep leg vein thrombosis. SYNOPSIS The management of established thrombosis has been transformed by low molecular weight heparins. http://www.australianprescriber.com/magazines/vol21no3/vein_thrombosis.htm

Treatment of deep leg vein thrombosis there is a comment for consumers on this article A.S. Gallus, Department of Haematology, Flinders Medical Centre, Adelaide (Aust Prescr 1998;21:64-6) SYNOPSIS The management of established thrombosis has been transformed by low molecular weight heparins. Their pharmacokinetics and dynamics allow them to be given subcutaneously in a dose determined by body weight alone. While this permits treatment of selected patients at home, great care is needed. The correct diagnosis remains essential because the risks of early recurrence and bleeding are little different from those observed with standard heparin. Symptomatic calf vein thrombosis should be treated. Index words: heparin, pulmonary embolism, warfarin. Treatment for established venous thrombosis Sixty years ago, before heparin came into general use, symptoms of deep leg vein thrombosis progressed from calf to thigh or to the opposite leg in 60% of untreated patients. Embolism occurred in 40% of those with thrombosis and half the patients with pulmonary embolism died. Today, we expect symptomatic extension or embolism in less than 5% of people treated for extensive deep leg vein thrombosis with standard heparin or a low molecular weight heparin followed by warfarin. Deaths from pulmonary embolism should be below 2%.

87. Coalition Formed To Raise Awareness Of DVT Article describing the goals of the Council for Leadership on thrombosis Awareness and Management. Requires free registration http://www.medscape.com/viewarticle/426817

88. Deep Vein Thrombosis And Travel There is community concern that air travel may increase the risk of deep vein thrombosis (DVT). DEEP VEIN thrombosis AND AIR TRAVEL. http://www.health.gov.au/pubhlth/strateg/communic/factsheets/thrombosis.htm

This site uses Javascript for its navigation, if you have javascript turned off please use the buttons on the left hand side of the page. Please select a topic from list... Alcohol Australia's Biosecurity Health Response Bovine Spongiform Encephalopathy (BSE) Breastfeeding National Child Nutrition Program Communicable Diseases National Comorbidity Project Disaster Medicine Environmental Health Falls Prevention for Older People Initiative Folate Food Policy Group Food Regulation Secretariat Health Inequalities Research Collaboration (HIRC) Hepatitis C HIV/AIDS Illicit Drug Diversion Initiative Immunise Australia Program Injury Prevention JETACAR Lifestyle Prescriptions National Drug Strategy National Illicit Drug Strategy (Tough on Drugs) National Health Strategy Papers Obesity Guidelines Physical Activity Pituitary Hormone Initiatives Population Health Social Marketing Promoting Healthy Weight Tobacco DEEP VEIN THROMBOSIS AND AIR TRAVEL ISSUE There has been growing media and community concern that air travel may increase the risk of deep vein thrombosis (DVT). The Department has recently completed a research project to assess the scale of any such risk. This project was funded by the Department of Transport and Regional Services. A summary of the results is provided at: FACT SHEET Health Advisory to Medical Practitioners Venous Thromboembolism (VTE Printable vervison (PDF file 59Kb)

89. Medical Experts Unite To Raise Awareness Of Risk, Threat Of Blood Clots Council for Leadership on thrombosis Awareness and Management formed to advance prevention and treatment of thrombosis. Includes disease description and council's education plans. http://www.eurekalert.org/pub_releases/2002-02/m-meu021302.php

Public release date: 14-Feb-2002 Contact: Kristen Supchak kristens@mcspr.com MCS Medical experts unite to raise awareness of risk, threat of blood clots Council for Leadership on Thrombosis Awareness and Management formed to advance prevention and treatment of overlooked public health problem TARRYTOWN, NY, February 14, 2002 Calling deep-vein thrombosis (DVT), or blood clots, an underestimated public health problem, the Council for Leadership On Thrombosis (CLOT) Awareness and Management announced its formation today to raise awareness, advance prevention and treatment, and reduce the dangers of DVT, a potentially life-threatening condition that affects approximately 2 million Americans per year. Comprised of medical experts representing various specialties and affiliated with leading U.S. institutions, the Council plans to target both health care professionals and the general public with such major initiatives as a national DVT FREE screening program of 7,500 patients at more than 200 hospitals, and the ClotAlert™ Resource Center, a multifaceted campaign to educate consumers, physicians and health professionals about the risk factors and symptoms of DVT. “Deep-vein thrombosis represents one of the most commonly occurring and serious medical conditions, yet it has never received the same attention as heart attack or stroke,” said Samuel Z. Goldhaber, MD, director of Venous Thromboembolism Research Group and Cardiac Center’s Anticoagulation Service at Brigham and Women’s Hospital in Boston, Mass., associate professor of medicine, Harvard Medical School, and co-chair of the Council for Leadership On Thrombosis Awareness and Management. “The public is not nearly as educated about the potential health risk of DVT, nor is the public aware of the symptoms associated with blood clots. Our mission as a Council is to raise awareness of DVT so the public can recognize the symptoms and urgently seek medical help.”

90. The American College Of Phlebology - Thrombosis And Thrombophlebitis thrombosis AND THROMBOPHLEBITIS. Jerry Ninia, MD, FACOG. Additionally, it is imperative to consider whether deep venous thrombosis (DVT) is also present. http://www.phlebology.org/syllabus12.htm

THROMBOSIS AND THROMBOPHLEBITIS Jerry Ninia, MD, FACOG Back to Primer Table of Contents Thrombophlebitis is a life-threatening complication of many medical conditions and surgical procedures and is neither rare nor limited to people with recognized risk factors. Epidemiological data have shown that in a given practice of 10,000 patients, 39 cases of venous thromboembolism(VTE) and 11 deaths from this cause will be recognized per year. In fact, the actual incidence is much higher, since most cases go undetected. One out of every nine people will develop DVT before age 80, and clinically recognized VTE accounts for one out every 20 deaths after age 50. These statistics make it imperative for us to have a high index of suspicion when signs and symptoms of this disorder are present. Superficial Thrombophlebitis Superficial thrombophlebitis (ST) occurs when there is inflammation and thrombus within a superficial vein and is most commonly seen in the lower extremity in association with varicose veins. It is due to the three basic components of Virchow's triad - venous stasis, endothelial damage and hypercoaguability - and is most frequently seen following trauma to a vein (external or internal) or a decrease in activity level, such as with travel. Typically, patients complain of localized tenderness, redness and warmth in association with a hard vein. Diffuse leg pain and edema are not uncommon, but the findings are usually more localized. Deep Venous Thrombosis

91. Thrombosis Research Institute. A multidisciplinary organization concerned with the interrelated problems of thrombosis and atherosclerosis. Provides articles for professionals and consumers. http://www.tri-london.ac.uk/

Thrombosis Research Institute Emmanual Kaye Building, Manresa Road,London SW3 6LR U.K. Tel: (44)20-7351-8330, Fax:(44)20-7351-8324 The TRI is a multidisciplinary organisation concerned with the interrelated problems of thrombosis and atherosclerosis. Our activities encompass drug discovery, basic scientific and clinical research with the aims of understanding the disease process, developing novel and affordable therapies whilst identifying those most at risk at an early age so as to intervene to prevent long-term disablement and early death. In this site you can find information covering all these aspects of our research in considerable detail as well as reviews on both the latest clinical treatments for thrombosis and the biochemistry of the coagulation cascade. You will also find a number of easy to understand articles for the interested lay person.You can navigate the site by means of the bar at the right of this page.

92. Clinical Study: 98-CC-0067, Treatment Of Acute Deep Vein Thrombosis Of The Lower Summary, detailed information, and eligibility requirements for this National Institutes of Health clinical trial to evaluate the efficiency, safety, and doses of a new spray treatment. http://clinicalstudies.info.nih.gov/detail/A_1998-CC-0067.html

Protocol Number: 98-CC-0067 Title: Treatment of Acute Deep Vein Thrombosis of the Lower Extremity with Intraclot, Pulse-Sprayed Recombinant Tissue Plasminogen Activator, Plus Heparin and Warfarin: A Pilot Study Number: 98-CC-0067 Summary: Acute deep venous thrombosis (ADVT) of the lower extremity is a common disorder. Traditional treatment with anticoagulation therapy is effective in reducing the associated risk of pulmonary embolism, but is ineffective in restoring patency of the venous system of the lower extremity. While systemic thrombolytic therapy has been shown to be more effective than anticoagulation, catheter directed local thrombolytic therapy is the most effective treatment in restoring venous patency. Current treatment regimens are based on use of urokinase, infused continuously through catheters imbedded into the thrombus. These treatment regimens require doses on the order of 10,000,000 units of urokinase, resulting in significant bleeding complications and prohibitive costs. Experience at NIH with pulse-spray treatment of axillary subclavian venous thrombosis with rtPA indicates that this is a highly effective and safe alternative thrombolytic regimen. The proposed protocol is designed to evaluate the efficiency, safety, and doses of rtPA associated with pulse spray directed rtPA treatment of the more extensive venous thrombosis encountered in the lower extremity.

93. PREVENT (Prevention Of Recurrent Venous Thromboembolism) Trial Aims to answer the question What is the best way to prevent the recurrence of blood clots in the legs and lungs? Features background information about thrombosis and its treatment plus information about the trial and patient eligibility. http://www.brighamandwomens.org/patient/optionalInterpage.asp?rso_abbrev=bwh&

94. Council On Arteriosclerosis, Thrombosis And Vascular Biology Welcome to the Arteriosclerosis, thrombosis and Vascular Biology Council content area. Council on Arteriosclerosis, thrombosis and Vascular Biology. http://www.americanheart.org/presenter.jhtml?identifier=1201

95. Cardiosource Deep Vein thrombosis DVT - Blood Clots in the Legs - Symptoms Learn about the causes, symptoms, diagnosis, treatment, and prevention of blood clots in the legs or deep vein thrombosis (DVT). What Is Deep Vein thrombosis? http://www.cardiosource.com/library/journals/journal?sdid=4887

96. Thrombosis-Consult.com www.freecme.com http://www.thrombosis-consult.com/

www.freecme.com www.freecme.com

97. Thrombosis Prevention: Online Reference For Health Concerns thrombosis Prevention description, symptoms, causes, nutritional supplements and treatment information. thrombosis Prevention Updated 06/26/2003. http://www.lef.org/protocols/prtcl-155.shtml

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98. Postgraduate Medicine: Patient Notes: Deep Vein Thrombosis Patient Notes Deep vein thrombosis. You probably have not heard much about deep vein thrombosis, even though it is a fairly common problem. http://www.postgradmed.com/issues/2000/09_00/pn_dvt.htm

Patient Notes Deep vein thrombosis VOL 108 / NO 4 / SEPTEMBER 15, 2000 / POSTGRADUATE MEDICINE You probably have not heard much about deep vein thrombosis, even though it is a fairly common problem. It is a disorder that affects mainly the veins of the lower leg and thigh. A blood clot (or thrombus) can form in the veins deep in these areas, and the clot then blocks the flow of blood and causes swelling and inflammation. This swelling and redness are sometimes called thrombophlebitis, or just phlebitis. In the most serious cases, a blood clot from the leg breaks off and travels through the bloodstream. The moving clot is called an embolus, and it can lodge in the lungs, brain, or heart and cause serious damage. Who is likely to have thrombosis? Deep vein thrombosis occurs in about 2 of every 1,000 people. Most often it affects persons over age 60. It tends to develop during long periods of inactivity, such as lengthy road trips or airplane flights, as well as during illness or after surgery. Sometimes it occurs because a person's blood clots too quickly, and sometimes it is associated with trauma. Old age, overweight, and some types of drug therapy also increase the risk. What do you need to know about it?

99. CNN.com - Health - Deep Vein Thrombosis Linked To Most Travel - March 13, 2001 International medical experts and officials from 16 major airlines across the globe on Tuesday heard a leading expert on deep vein thrombosis link the http://www.cnn.com/2001/HEALTH/conditions/03/13/deep.vein.thrombosis.02/

MAIN PAGE WORLD U.S. WEATHER ... ABOUT US CNN TV what's on show transcripts CNN Headline News CNN International ... askCNN EDITIONS CNN.com Asia CNN.com Europe set your edition Languages Spanish Portuguese German Italian Danish Japanese Korean Arabic Time, Inc. Time.com People Fortune EW Deep vein thrombosis linked to most travel From staff and wire reports GENEVA, Switzerland International medical experts and officials from 16 major airlines across the globe on Tuesday heard a leading expert on deep vein thrombosis link the condition to most types of travel. Organized by the World Health Organization's cardiovascular disease unit, the closed-door meetings in Geneva, Switzerland, began Monday and concluded Tuesday. "Travel-related thrombosis is a better name," Dr. John Scurr, a British surgeon who has studied the syndrome, told Reuters. "Studies have shown it is a common travel problem." Scurr is a surgeon at Middlesex and University College Hospital in London, England. PREVENTION Snacking, moving can decrease risk of flight-related blood clots Also speaking Tuesday was Dr. Derek Yach of the WHO, who agreed with Scurr that deep vein thrombosis is probably a bigger issue than it currently appears to be. Physicians say the condition is still rare, however. Gregory Hartl, a spokesman for the United Nations health agency, called the two-day meeting significant. "We've come to this with an open mind. We need to review the research done and see what gaps need filling and what, how and when it needs to be done on an international scale," he told The Associated Press.

100. MSRGSNet/Genetic Drift/Venous Thrombosis And The Factor V (Leiden) Mutation Venous thrombosis and the Factor V (Leiden) Mutation. Factor V mutation in women s health; Diagnostic workup of patients with inherited thrombosis; http://www.mostgene.org/gd/gdvol14b.htm

Previous Section This Issue- Table of Contents Next Section Vol. 14: Spring, 1997 Molecular Genetic Testing in Mainstream Medicine Venous Thrombosis and the Factor V (Leiden) Mutation Introduction Who should be tested? Deep vein thrombosis and pulmonary embolism Known genetic causes ... Illustrative case report Introduction Who should be tested? Indications include: Venous thrombosis or pulmonary embolism Transient ischemic attacks or premature stroke Peripheral vascular disease, particularly lower extremity occlusive disease History of a thrombotic event Family history of thrombosis or known factor V mutation in a relative Prior to major surgery, pregnancy, postpartum, oral contraceptive use or estrogen therapy if there is a personal or family history of thrombosis. Previous finding of activated protein C resistance by laboratory analysis Deep vein thrombosis and pulmonary embolism Venous thrombosis and pulmonary embolism pose a serious health problem. In this country half a million people are hospitalized each year and 50,000-100,000 deaths occur due to venous thrombosis which is also a leading cause of maternal death. The incidence of symptomatic venous thrombosis cases is approximately 1 in 1000 people per year. Venous thrombosis is a multifactorial condition caused by a combination of genetic, aquired or environmental influences. Natural anticoagulant systems (the protein C system and antithrombin III) are in place to keep coagulation in check. Excess clotting occurs when there is a disturbance in one of the coagulation inhibitor mechanisms or in natural lysis of clots.

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