61. Tay-Sachs Disease: The Absence Of Hope taysachs disease The Absence of Hope. Lauren Friedman. tay-sachs disease was named for Warren Tay and Bernard Sachs, two doctors working independently. http://serendip.brynmawr.edu/biology/b103/f02/web1/lfriedman.html

This paper was written by a student in a course at Bryn Mawr College, and reflects that student's research and thoughts at the time the paper was written. Like other things on Serendip , the paper is not intended to be "authoritative" but is instead provided to encourage others to themselves learn about and think through subjects of interest, and, by providing relevant web links, to serve as a "window" to help them do so. Web links were active as of the time the paper was posted but are not updated. Biology 103 2002 First Paper On Serendip Tay-Sachs Disease: The Absence of Hope Lauren Friedman Introduction. When a couple has a baby, they pray that they will have an easy childbirth and a healthy newborn. However, an easy delivery and a healthy-seeming baby does not guarantee a problem-free childhood. Children born with Tay-Sachs Disease (TSD), a fatal genetic disorder, do not show symptoms until they are six months old, but almost never survive past the age of five. Tay-Sachs Disease was named for Warren Tay and Bernard Sachs, two doctors working independently. In 1881, Dr. Tay, an ophthalmologist, described a patient with a cherry red spot on the back of his eye; the presence of this red spot has become a clear signal for the diagnosis of TSD. Several years later, Dr. Sachs, a New York neurologist, described the cellular changes caused by TSD, observed the hereditary nature of the disease, and noted its predominance among Jews of Eastern European descent A rarer form of the disease known as Late-Onset Tay-Sachs exists, but this paper will focus on classic infantile TSD and explore its scientific and social implications.

62. Virtual Hospital : Health Topics A-Z : Tay-Sachs Disease taysachs disease. All Topics Adult Patient Topics Adult Provider Topics Pediatric Patient Topics Pediatric Provider Topics. For Pediatric Providers. http://www.vh.org/navigation/vh/topics/pediatric_provider_tay-sachs_disease.html

Health Topics A-Z Tay-Sachs Disease All Topics Adult Patient Topics Adult Provider Topics Pediatric Patient Topics ... Pediatric Provider Topics For Pediatric Providers Clinical Genetics: A Self-Study Guide for Health Care Providers All Topics Adult Patient Topics Adult Provider Topics ... UI Health Care Home http://www.vh.org/navigation/vh/topics/pediatric_provider_tay-sachs_disease.html

63. Tay-Sachs Disease Self Help Clearinghouse. taysachs disease. Late Onset Tay-Sachs Foundation. National network. Founded 1994. Support and education http://www.bchealthguide.org/kbase/shc/shc29tay.htm

document.write(''); var hwPrint=1; var hwDocHWID="shc29tay"; var hwDocTitle="Tay-Sachs Disease"; var hwRank="1"; var hwSectionHWID="shc29tay"; var hwSectionTitle=""; var hwSource="cn6.0"; var hwProdCfgSerNo="wsh_html_031_s"; var hwDocType="SHC"; Self Help Clearinghouse Tay-Sachs Disease Late Onset Tay-Sachs Foundation National network. Founded 1994. Support and education for persons dealing with late onset Tay-Sachs. Aims to educate medical and community at large. Advocacy, newsletter, information and referrals, phone support, conferences, fundraising for research, and literature. WRITE: Late Onset Tay-Sachs Foundation P.O. Box 5 Flourtown, PA 19031-0005 CALL: 1-800-672-2022 (day) FAX: 215-836-5438 E-MAIL: lostf@verizon.net WEBSITE: http://www.lotsf.org VERIFIED: 9/10/2003 National Tay-Sachs and Allied Diseases Association National. 4 affiliated groups. Founded 1957. (Bilingual) Dedicated to the treatment and prevention of Tay-Sachs, Canavan, and related genetic diseases. Provides information and support services to individuals and families affected by these disorders as well as the public at large. The strategies for achieving these goals include public and professional education, research, genetic screening, family services (i.e. Parent Peer Group and Grandparent Group), and advocacy. WRITE: National Tay-Sachs and Allied Diseases Association 2001 Beacon St., Suite 204

64. Tay-Sachs Disease - Encyclopedia Article About Tay-Sachs Disease. Free Access, N taysachs disease. Word Word. Infants with tay-sachs disease appear to develop normally for the first few months of life. http://encyclopedia.thefreedictionary.com/Tay-Sachs disease

Dictionaries: General Computing Medical Legal Encyclopedia Tay-Sachs disease Word: Word Starts with Ends with Definition Tay-Sachs disease is a fatal genetic disorder A genetic disorder , or genetic disease is a disease caused, at least in part, by the genes of the person with the disease. There are a number of possible causes for genetic defects: They may be caused by an unwelcome mutation, as are most cancers. There are genetic disorders caused by the accidental duplication of a chromosome, as in Down syndrome, or repeated duplication of part of a chromosome as in Fragile X syndrome. The defective genes are often inherited from the person's parents. In this case, the genetic disorder is known as a hereditary disease . This can often happen unxpectedly when two healthy carriers of a defective recessive gene reproduce, but can also happen when the defective gene is dominant. Click the link for more information. in which harmful quantities of a fatty substance called ganglioside GM2 accumulate in the nerve cells Neurons (also called nerve cells ) are the primary cells of the nervous system.

65. Health Care Information Resources Tay-Sachs Disease Links The address of this page is http//hsl.mcmaster.ca/tomflem/taysachs.html. taysachs disease Links. For more information, see Genetic http://www-hsl.mcmaster.ca/tomflem/taysachs.html

The address of this page is: http://hsl.mcmaster.ca/tomflem/taysachs.html Tay-Sachs Disease Links For more information, see: Genetic conditions , also in the Illness section of this resource. Tay-Sachs disease - National Tay-Sachs and Allied Diseases Association a fatal genetic disorder in children Tay-Sachs disease - National Tay-Sachs and Allied Diseases of Ontario rare genetic diseases that affect children Tay-Sachs disease - Tay-Sachs Disease info from the National Foundation for Jewish Genetic Diseases, Inc. Tay-Sachs disease - Tay-Sachs Disease Information Page from the U.S. NINDS Tay-Sachs disease - Tay-Sachs Disease Your Genes Your Health Please read

66. Tay-Sachs Disease taysachs disease Presentation is usually at six months of age when affected infants, who previously have appeared normal and passed their early milestones http://www.sas-centre.org/genetic/genpages/lysstodistaysachsdisease.html

Tay-Sachs Disease Presentation is usually at six months of age when affected infants, who previously have appeared normal and passed their early milestones, become lethargic, floppy and poor feeders. They show an abnormal accentuated startle response to sudden noises. There is usually a macular cherry-red spot. Motor development becomes progressively retarded and as the disease progresses blindness, spasticity and decerebrate rigidity occur. Feeding becomes increasingly difficult and death usually occurs by 3 years following pulmonary infection. Later onset forms of the disease with juvenile or adult presentation and sub-acute or chronic courses also occur. In these there may be survival into adolescence, or longer survival with normal intelligence but slowly progressive spinocerebellar degeneration. Enzyme Test: b -Hexosaminidase A is measured for diagnosis of this disease. Back to Lysosomal Storage Disorders Index

67. Your Health - Tay-Sachs Disease other. taysachs disease. by Jenna Hollenstein, MS, RD. Definition. tay-sachs disease (TSD) is a fatal genetic disorder. It http://www.aurorahealthcare.org/yourhealth/healthgate/getcontent.asp?URLhealthga

68. CCHS Clinical Digital Library Clinical Resources by Topic Metabolic Disorders. taysachs disease Clinical Resources. Miscellaneous tay-sachs disease Clinical Resources. http://cchs-dl.slis.ua.edu/clinical/metabolism/inborn/lysosomalstorage/sphingoli

Clinical Resources by Topic: Metabolic Disorders Tay-Sachs Disease Clinical Resources Pediatrics Pathology Genetics Clinical Guidelines ... Miscellaneous Resources See also: Genetic Testing Clinical Resources Mental Retardation Clinical Resources General Genetic Disorders Clinical Resources General Metabolic Disorders Resources ... Tay Sachs Disease Patient/Family Resources Harrison's Principles of Internal Medicine 15th Ed.-2001: Table of contents Health Sciences Library subscription INFO Chapter 349: Lysosomal Storage Diseases: Table of contents General Features: Access document Physiology of Lysosomes: Access document Pathogenesis of Lysosomal Storage Diseases: Access document Specific Disorders: Access document GM2 Gangliosidoses: Access document Chapter 365: Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases Table of contents Selected Disorders of the Lower Motor Neuron: Access document Hoffman: Hematology: Basic Principles and Practice 3rd Ed.-2000 (MD Consult): Table of contents Health Sciences Library subscription INFO Chapter 44 - Lysosomal Storage Diseases: Perspective and Principles: Access document The Concept of the Lysosome: Access document Physiology of Lysosomes: Access document Pathophysiology of Lysosomal Storage Diseases: Access document Molecular Genetic Mechanisms of Lysosomal Storage Diseases: Access document Genotype/Phenotype Correlations: Access document Therapeutic Approaches and Implications: Access document Results and Lessons from Therapy: Access document Diagnosis of Lysosomal Storage Diseases: Access document Goetz: Textbook of Clinical Neurology 2nd Ed.-2003 (MD Consult):

69. CCHS Clinical Digital Library taysachs disease Patient/Family Resources. tay-sachs disease English Spanish. Merck Manual - Second Home Edition Table of contents Section 23. http://cchs-dl.slis.ua.edu/patientinfo/metabolism/inborn/lysosomalstorage/sphing

Patient/Family Resources by Topic: Metabolic Disorders Tay-Sachs Disease Patient/Family Resources Spanish Miscellaneous See also: Mental Retardation Patient/Family Resources Genetic Testing Patient/Family Resources General Genetic Disorders Patient/Family Resources General Metabolic Disorders Patient/Family Resources ... Tay-Sachs Disease Clinical Resources National Tay-Sachs and Allied Diseases Association: Homepage Profiles of Allied Diseases: List of documents Tay-Sachs Disease: Access document Late-Onset Tay-Sachs Disease: Access document March of Dimes: Homepage Facts Sheets: List of documents Tay-Sachs Disease: Access document National Institute of Neurological Disorders and Stroke: Homepage Disorders Information: List of documents Tay-Sachs Disease: Access document MEDLINE plus Medical Encyclopedia: Table of contents Tay-Sachs Disease: English Spanish Merck Manual - Second Home Edition Table of contents Section 23. Children's Health Issues: Table of contents Chapter 282. Hereditary Disorders of Metabolism: Table of contents Introduction: Access document Lipid Metabolism Disorders: Access document Introduction: Access document Tay-Sachs Disease: Access document Complete Home Medical Guide: Table of contents Brain, Nerve, and Muscle Disorders:

70. Tay-Sachs Disease. The Columbia Encyclopedia, Sixth Edition. 2001 taysachs disease. tay-sachs disease occurs primarily among Jews of Eastern European descent but is also found in French Canadians whose roots are in the St. http://www.bartleby.com/65/ta/Tay-Sach.html

Select Search All Bartleby.com All Reference Columbia Encyclopedia World History Encyclopedia Cultural Literacy World Factbook Columbia Gazetteer American Heritage Coll. Dictionary Roget's Thesauri Roget's II: Thesaurus Roget's Int'l Thesaurus Quotations Bartlett's Quotations Columbia Quotations Simpson's Quotations Respectfully Quoted English Usage Modern Usage American English Fowler's King's English Strunk's Style Mencken's Language Cambridge History The King James Bible Oxford Shakespeare Gray's Anatomy Farmer's Cookbook Post's Etiquette Bulfinch's Mythology Frazer's Golden Bough All Verse Anthologies Dickinson, E. Eliot, T.S. Frost, R. Hopkins, G.M. Keats, J. Lawrence, D.H. Masters, E.L. Sandburg, C. Sassoon, S. Whitman, W. Wordsworth, W. Yeats, W.B. All Nonfiction Harvard Classics American Essays Einstein's Relativity Grant, U.S. Roosevelt, T. Wells's History Presidential Inaugurals All Fiction Shelf of Fiction Ghost Stories Short Stories Shaw, G.B. Stein, G. Stevenson, R.L. Wells, H.G. Reference Columbia Encyclopedia PREVIOUS NEXT ... BIBLIOGRAPHIC RECORD The Columbia Encyclopedia, Sixth Edition. Tay-Sachs disease (t KEY ) , rare hereditary disease caused by a genetic mutation that leaves the body unable to produce an

71. Tay-Sachs Disease. The American Heritage® Dictionary Of The English Language: F The American Heritage ® Dictionary of the English Language Fourth Edition. 2000. taysachs disease. PRONUNCIATION t s ks. NOUN A http://www.bartleby.com/61/75/T0067500.html

Select Search All Bartleby.com All Reference Columbia Encyclopedia World History Encyclopedia Cultural Literacy World Factbook Columbia Gazetteer American Heritage Coll. Dictionary Roget's Thesauri Roget's II: Thesaurus Roget's Int'l Thesaurus Quotations Bartlett's Quotations Columbia Quotations Simpson's Quotations Respectfully Quoted English Usage Modern Usage American English Fowler's King's English Strunk's Style Mencken's Language Cambridge History The King James Bible Oxford Shakespeare Gray's Anatomy Farmer's Cookbook Post's Etiquette Bulfinch's Mythology Frazer's Golden Bough All Verse Anthologies Dickinson, E. Eliot, T.S. Frost, R. Hopkins, G.M. Keats, J. Lawrence, D.H. Masters, E.L. Sandburg, C. Sassoon, S. Whitman, W. Wordsworth, W. Yeats, W.B. All Nonfiction Harvard Classics American Essays Einstein's Relativity Grant, U.S. Roosevelt, T. Wells's History Presidential Inaugurals All Fiction Shelf of Fiction Ghost Stories Short Stories Shaw, G.B. Stein, G. Stevenson, R.L. Wells, H.G. Reference American Heritage Dictionary tayra ... BIBLIOGRAPHIC RECORD The American Heritage Dictionary of the English Language: Fourth Edition.

72. SupportPath.com: Tay-Sachs Disease SupportPath.com, taysachs disease. Professional Organizations of Interest None Listed. Clinical Trials Research on tay-sachs disease http://www.supportpath.com/sl_t/tay_sachs_disease.htm

Tay-Sachs Disease A fatal inherited disorder in which an excess of a fatty substance accumulates in the brain's nerve cells leading to severe mental and physical deterioration. Most children with Tay-Sachs Disease die before age 5. Other topics of interest on SupportPath.com: Bereavement Rare Disorders About Us Add-A-Link ... here Online Communities / Message Boards... None Listed Online Chats... Note: Regularly scheduled chats are listed on our NEW Online Events Calendar Links in this section are primarily to chat rooms open 24/7 which may or may not be moderated. None Listed Usenet Groups... Note: Your browser must be properly configured to access Usenet groups from this site. None Listed Mailing Lists... None Listed National / International Organizations... UNITED STATES Late-Onset Tay-Sachs Foundation (LOTSF) Website: http://www.lotsf.org/ Description: As of 05/31/2002, the website is being updated. Date Added: 05/31/2002 UNITED STATES The National Foundation for Jewish Genetic Diseases, Inc. (NFJGD) Website: http://www.nfjgd.org/ Description: The NFJGD "is devoted to supporting research and informing both the public and the medical community about these, the nine most common Ashkenazi Jewish genetic diseases." View their

73. Blackwell Synergy - Cookie Absent Short Report. Evaluation of a taysachs disease screening program. tay-sachs disease (TSD) is an autosomal recessive neurodegenerative disorder. http://www.blackwell-synergy.com/links/doi/10.1034/j.1399-0004.2003.00074.x/abs/

Home An Error Occurred Setting Your User Cookie A cookie is a small amount of information that a web site copies onto your hard drive. Synergy uses cookies to improve performance by remembering that you are logged in when you go from page to page. If the cookie cannot be set correctly, then Synergy cannot determine whether you are logged in and a new session will be created for each page you visit. This slows the system down. Therefore, you must accept the Synergy cookie to use the system. What Gets Stored in a Cookie? Synergy only stores a session ID in the cookie, no other information is captured. In general, only the information that you provide, or the choices you make while visiting a web site, can be stored in a cookie. For example, the site cannot determine your email name unless you choose to type it. Allowing a web site to create a cookie does not give that or any other site access to the rest of your computer, and only the site that created the cookie can read it. Please read our for more information about data collected on this site.

74. Dynagene Information For Patients - Tay Sachs Disease Patient Education Tay Sachs, print. tay-sachs disease. An infant with tay-sachs disease usually develops in a normal manner for the first few months of life. http://www.dynagene.com/education/tay.html

Client Services Testing Services Genetic Counseling For Patients ... News Room Houston 7400 Fannin Suite 1200 Houston, TX 77054 Tel: 713 798 9500 Fax: 713 798 9595 Toll Free: 800 543 1346 Seattle 819 Boylston Ave. 2nd Floor Seattle, WA 98104 Tel: 206 386 6166 Fax: 206 386 2631 Toll Free: 800 458 6836 Patient Education Tay Sachs print Tay-Sachs Disease Characteristics Inheritance What is the cause of Tay-Sachs disease? Recommendations ... Where can I learn more about Tay-Sachs disease? Tay-Sachs disease is an inherited genetic disorder which is most prevalent among descendants of the Ashkenazi Jewish population from Central and Eastern Europe. Approximately 1 out of every 30 Jewish Americans is a carrier of the Tay-Sachs gene. More recently, an increased incidence has been noted in people of French-Canadian and Cajun ancestry, but in all other populations, the frequency of Tay-Sachs has significantly decreased. Characteristics An infant with Tay-Sachs disease usually develops in a normal manner for the first few months of life. However, at about six months of age, the baby begins to lose its ability to do things such as roll over, crawl, or reach out for something. He or she many even lose the ability to smile. Over time, the baby will become completely unaware of his/her surroundings. Mental retardation always occurs, and progressive physical deterioration causes the baby to become blind and paralyzed. The average life expectancy for a person with Tay-Sachs disease is 2-5 years of age.

75. Print Version - Tay Sachs Disease taysachs disease. Characteristics Inheritance What is the cause of tay-sachs disease? Recommendations Where can I learn more about tay-sachs disease? http://www.dynagene.com/print/tay.html

Tay-Sachs Disease Characteristics Inheritance What is the cause of Tay-Sachs disease? Recommendations Where can I learn more about Tay-Sachs disease? Tay-Sachs disease is an inherited genetic disorder which is most prevalent among descendants of the Ashkenazi Jewish population from Central and Eastern Europe. Approximately 1 out of every 30 Jewish Americans is a carrier of the Tay-Sachs gene. More recently, an increased incidence has been noted in people of French-Canadian and Cajun ancestry, but in all other populations, the frequency of Tay-Sachs has significantly decreased. Characteristics An infant with Tay-Sachs disease usually develops in a normal manner for the first few months of life. However, at about six months of age, the baby begins to lose its ability to do things such as roll over, crawl, or reach out for something. He or she many even lose the ability to smile. Over time, the baby will become completely unaware of his/her surroundings. Mental retardation always occurs, and progressive physical deterioration causes the baby to become blind and paralyzed. The average life expectancy for a person with Tay-Sachs disease is 2-5 years of age. Inheritance Tay-Sachs disease has an autosomal (non-sex related) recessive pattern of inheritance, meaning that both parents must be carriers in order to have an affected child. If both parents are carriers of the Tay-Sachs gene, their child has a 25% chance of having the disease, a 50% chance of being an asymptomatic carrier, and a 25% chance of being disease-free and not carrying the gene. If only one parent is a Tay-Sachs carrier, there is no chance of having an affected child, and a 50% chance the child will be a carrier.

76. Tay-Sachs Disease | Www.somethingjewish.co.uk taysachs disease is an inherited metabolic disorder. The identified. tay-sachs disease is inherited in an autosomal recessive manner. http://www.somethingjewish.co.uk/articles/370_tay_sachs_disease.htm

HOME CONTACT US JOIN OUR FREE MAILING LIST JEWISH BLOGS ... WORLD NEWS SEARCH Home Page About Us Buy Jewish and Israeli gifts Suzie Gold ... You Are Wanted Last Updated: >>More from SJ Health E-mail this to a friend Tay-Sachs Disease Tay-Sachs disease is the most well known Jewish genetic disease, potentially affecting one in every 2,500 Ashkenazi Jewish newborns. Two forms of this disease occur in Ashkenazi Jews, the well known infantile-onset form and a lesser known, late-onset or adult form designated "chronic GM2-gangliosidosis". Infantile Tay-Sachs Disease This disease is characterized by the onset of severe mental and developmental retardation during the first four to eight months of life. An early sign of the disease is the cherry-red spot, an unusual abnormality in the retina of the eye observed only by use of an ophthalmoscope. The involvement of the central nervous system progresses rapidly and affected children become totally debilitated by two to five years of life. Affected children also develop seizures which are not controllable with anti-epileptic drugs. Death usually occurs by three to five years of life due to pneumonia or other infections. Tay-Sachs disease is an inherited metabolic disorder. The basic defect in affected children is the deficiency of an enzyme, Beta-hexosaminidase A. This enzyme normally breaks down a naturally occurring fatty substance called GM2-ganglioside. The enzyme deficiency leads to a toxic accumulation of GM2-ganglioside in the cells of the nervous system. The gene for hexosaminidase A has been isolated on chromosome 15 and several specific mutations which cause infantile Tay-Sachs disease in Ashkenazi Jewish individuals have been identified.

77. Tay Sachs Disease,Amaurotic Familial Idiocy,Amaurotic Familial Infantile Idiocy, Information about taysachs disease (pamphlet). 1998. ^Top. http//www.mtsinai.on.ca/familymedicine/genetics/Disorders/taysachs.htm Mount Sinai Hospital http://www.icomm.ca/geneinfo/taysachs.htm

Tay Sachs Disease,Amaurotic Familial Idiocy,Amaurotic Familial Infantile Idiocy,Cerebromacular Degeneration,GM2 Gangliosidosis Type 1,Hexoaminidase Alpha-Subunit Deficiency (Variant B),Infantile Cerebral Ganglioside,Infantile Sipoidosis GM-2 Gangliosideosis (Type S),Lipidosis ganglioside infantile,Tay Sachs Sphingolipidosis For Information on Workshops and Seminars for Special Needs Children click here The GAPS INDEX to Information on the Internet about Genetic Disorders and Birth Defects Genetic Information and Patient Services, Inc. (GAPS) HOME DISORDERS GLOSSARY Tay Sachs Disease See also "The Tragedy of Tay Sachs" also known as: Amaurotic Familial Idiocy Amaurotic Familial Infantile Idiocy Cerebromacular Degeneration GM2 Gangliosidosis, Type 1 Hexoaminidase Alpha-Subunit Deficiency (Variant B) Infantile Cerebral Ganglioside Infantile Sipoidosis GM-2 Gangliosideosis (Type S) Lipidosis, ganglioside, infantile Sphingolipidosis, Tay-Sachs (as defined by the National Organization for Rare Disorders Tay-Sachs disease is a rare, neurodegenerative disorder in which deficiency of an enzyme (hexosaminidase A) results in excessive accumulation of certain fats (lipids) known as gangliosides in the brain and nerve cells. This abnormal accumulation of gangliosides leads to progressive dysfunction of the central nervous system.

78. Tay-sachs Disease taysachs disease, Tay-Sachs rank 1000 tay-sachs disease. Site Map Privacy Contact Advertise Health Directory Copyright 2000-2004. http://www.thenewhealthfind.com/health/tay-sachs disease

tay-sachs disease Tay Sachs rank:       Directory   Home: Health: Conditions and Diseases: Nutrition and Metabolism Disorders: Cholesterol and Other Fats: Tay Sachs (4) See Also: Health: Conditions and Diseases: Genetic Disorders Health: Conditions and Diseases: Neurological Disorders: Brain Diseases: Metabolic Health: Conditions and Diseases: Rare Disorders National Tay Sachs and Allied Diseases Association - An organization offering support and programs geared to families affected by Tay Sachs Disease and over 40 other fatal degenerative genetic disorders. Tay Sachs Disease - A description along with prognosis and treatment of this disease Tay Sachs Disease - Information sheet on this disease addressing what it is, treatment and prognosis. Tay Sachs Disease Rare Disorders rank:       Directory   Home: Health: Conditions and Diseases: Rare Disorders (119) Aarskog Syndrome@ (6) Aase Syndrome@ (3) Abetalipoproteinemia@ (4) Ablepharon-Macrostomia Syndrome@ (4) Adie Syndrome@ (5) Adrenoleukodystrophy@ (8) Agnosia (3) Aicardi Syndrome (8) Alagille Syndrome@ (6) Alstrom Syndrome (6) Alternating Hemiplegia@ (3) Apert Syndrome@ (9) Arthrogryposis@ (103) Ataxia@ (10) Bardet-Biedl Syndrome@ (6) Barth Syndrome (3) Behcet's Syndrome@ (6) Blastomycosis@ (4) Botulism@ (4) Celiac@ (39) Cerebrocostomandibular Syndrome (2) Charcot-Marie-Tooth Disease Genetic Disorders rank:       Directory   Home: Health: Conditions and Diseases: Genetic Disorders (628) Aarskog Syndrome (6) Aase Syndrome (3) Ablepharon-Macrostomia Syndrome (4) Acoustic Neuroma@ (14) Adie Syndrome@ (5) Adrenal Hyperplasia@ (18) Adrenoleukodystrophy@ (8) Aicardi Syndrome@ (8) Alagille Syndrome (6) Albinism@ (11) Alkaptonuria (4) Alopecia Areata@ (17) Alpha-1 Antitrypsin Deficiency (8) Alstrom Syndrome@ (6) Angelman Syndrome@ (14) Apert Syndrome@ (9) Arthrogryposis@ (103) Ataxia@ (10) Autism@ (676) Bardet-Biedl Syndrome@ (6) Barth Syndrome@ (3) Batten (7) Beckwith-Wiedemann Syndrome (5) Canavan@ (4) Celiac@ (39) Cerebrocostomandibular Syndrome@ (2) Charcot-Marie-Tooth

79. Tay-Sachs Disease Prevention - Wolper Hospital What is taysachs disease? tay-sachs disease (TSD) is an inherited (genetic), incurable disease of the central nervous system. Who gets tay-sachs disease? http://www.wolper.com.au/Programs/Tay-Sachs/tay-sachs.html

What is Tay-Sachs disease? Tay-Sachs disease (TSD) is an inherited (genetic), incurable disease of the central nervous system. In the classical form, symptoms first appear at about the age of 6 months, when an apparently healthy baby stops smiling, crawling or turning over, loses their ability to grasp or reach out, and gradually becomes blind and paralysed. There is no cure for the disease and death usually occurs before the age of five years. Babies with TSD do not have the correct genetic information to tell his/her body to produce an enzyme called B-Hexosaminidase A (HexA), which is necessary for breaking down certain substances in the brain and nerve cells. These substances then accumulate in the nerve cells causing irreversible damage. Who gets Tay-Sachs disease? Genetic diseases are often more common in specific community groups. TSD is most common amongst descendants of Central and Eastern European (Ashkenazi) Jews and some French Canadians. What causes Tay-Sachs disease? TSD is caused by inheriting a 'double-dose' of a fault in a gene which codes for the HexA enzyme. Every person has two copies of this gene in each cell of their body. A person will only be affected by TSD if s/he has a fault (mutation) in both copies of the HEXA gene. This can only happen if one faulty copy is inherited from each parent. About one in every 26 Ashkenazi Jews and 1 in every 40 French Canadians carries one copy of the faulty gene and one regular copy of the gene. In the general population, however, only about one in 300 people carry a faulty copy of the HEXA gene. Carriers themselves are not affected by the disease.

80. Tay-Sachs Disease Lawsuit Overview - Find Trial Lawyers And Attorneys With Exper taysachs disease. If you the brain. Infants with tay-sachs disease appear to develop normally for the first few months of life. http://www.injuryboard.com/view.cfm/Topic=1249

June 2, 2004 Hundreds of thousands of Americans are hospitalized each year due to chronic liver disease and cirrhosis Vioxx / Rofecoxib Tractor-Trailer Accidents Serzone / Nefazodone Hydrochloride Tort Reform ... Injuries Tay-Sachs Disease If you or a family member has been injured, contact a personal injury attorney today. Just fill out InjuryBoard.com's on-line questionnaire and have a personal injury lawyer review your potential personal injury claim - free of charge. Ask an Attorney Tay-Sachs disease is a fatal genetic disorder in which harmful quantities of a fatty substance called ganglioside GM2 accumulate in the nerve cells in the brain. Infants with Tay-Sachs disease appear to develop normally for the first few months of life. Then, as nerve cells become distended with fatty material, a relentless deterioration of mental and physical abilities occurs. The child becomes blind deaf , and unable to swallow. Muscles begin to atrophy and paralysis sets in.

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Page 4     61-80 of 99    Back | 1  | 2  | 3  | 4  | 5  | Next 20