61. Neurological Disorders - Spinal Muscular Atrophy Print Version. Neurological Disorders spinal muscular atrophy. What is spinal muscular atrophy (SMA)? What causes spinal muscular atrophy? http://www.musckids.com/health_library/neuro/sma.htm

Home About Us Departments Send an e-Card ... Your Hospital Visit 171 Ashley Ave. Charleston, SC 29425 800-424-MUSC Print Version Neurological Disorders Spinal Muscular Atrophy What is spinal muscular atrophy (SMA)? Spinal muscular atrophy is a degenerative problem that affects the spinal cord and nerves, resulting in muscle wasting and weakness. Spinal muscular atrophy occurs in approximately one in 6,000 live births. What causes spinal muscular atrophy? SMA is an autosomal recessive disease. This means that both males and females are equally affected, and that two copies of the gene, one inherited from each parent, are necessary to have the condition. A gene called survival motor neuron (or SMN) is found to have an abnormal area (called a deletion) in over 95 percent of cases of SMA. Symptomatic individuals of all ages can be tested through DNA studies typically done from a blood sample. When both parents are carriers, there is a one in four, or 25 percent, chance, with each pregnancy, to have a child with SMA. Carrier testing for the general population is technically difficult and usually available only if a previously affected child in the family has been studied. What are the symptoms of spinal muscular atrophy?

62. Dorlands Medical Dictionary Cruveilhier s atrophy, spinal muscular a. myelopathic muscular atrophy, muscular atrophy due to lesion of the spinal cord, as in spinal muscular atrophy. http://www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspzQzpgzEzzSzppdocszSzuszS

63. The DRM WebWatcher: Spinal Muscular Atrophy (SMA) A Disability Resources Monthly guide to the best online resources about spinal muscular atrophy (SMA). http://www.disabilityresources.org/SMA.html

Home WebWatcher Regional Librarians ... Contact Us The DRM WebWatcher Spinal Muscular Atrophy (SMA) Updated 6/17/2001 A B C D ... About/Hint/Link Spinal muscular atrophy (SMA) is a genetic, motor neuron disease characterized by wasting of the skeletal muscles caused by progressive degeneration of the anterior horn cells of the spinal cord. There are various forms of SMA, including Werdnig-Hoffman Disease, Kugelberg-Welander Disease and Kennedy Disease. Here are some good resources about SMA. Andrew's Buddies (fightsma.com) Andrew's Buddies is "a national organization committed to accelerating a cure for spinal muscular atrophy (SMA)." The organization funds SMA genetic work, the identification of promising compounds for SMA treatment, and the development of strategies to increase the production of the missing protein in SMA. Its website provides a good explanation of the genetics of SMA as well as current research news. Facts About Spinal Muscular Atrophy (SMA) This brochure from the Muscular Dystrophy Association (U.S.) addresses frequently asked questions about SMA as well as the role of the Association in finding a treatment or cure. Families of SMA Home Page Families of SMA is a nonprofit organization that raises funds to promote research into the causes and cure of SMA and supports families affected by SMA. Its website is packed with information and resources about SMA, research news, message boards, a kids' section, and much more.

64. Jennifer Trust For Spinal Muscular Atrophy Medical Helpsites. +, Jennifer Trust for spinal muscular atrophy, Address, Tel, Info, home page of the jennifer trust for spinal muscular atrophy. Report Dead Link, http://www.4ni.co.uk/listing.asp?cat=39&style=0&company=96568&level1=18

65. Neurological Disorders - Spinal Muscular Atrophy For a doctor who specializes in this topic, click here. spinal muscular atrophy. What is spinal muscular atrophy (SMA)? What causes spinal muscular atrophy? http://www.chkd.org/Neurology/sma.asp

More Health Information Adolescent Medicine Allergy/Immunology Anesthesiology Arthritis Burns Cardiology Craniofacial Dental Medicine Dermatology Developmental Peds Diabetes Digestive Ear, Nose, Throat Genetics Gastroenterology Growth Hematology High Risk Newborn High Risk Pregnancy Infectious Disease Mental Health Neonatology Nephrology Neurology Normal Newborn Normal Pregnancy Oncology Ophthalmology Orthopedics Otolaryngology Pediatric Intensive Care Pediatric Surgery Pediatrics Physical Medicine Plastic Surgery Respiratory/Pulmonology Rheumatology Safety Surgery Terminal Transplant Urology Site Search For a doctor who specializes in this topic, click here. Spinal Muscular Atrophy What is spinal muscular atrophy (SMA)? Spinal muscular atrophy is a rare degenerative problem that affects the spinal cord and nerves, resulting in muscle wasting and weakness. What causes spinal muscular atrophy? SMA is an autosomal recessive disease. This means that both males and females are equally affected, and that two copies of the gene, one inherited from each parent, are necessary to have the condition.A gene called survival motor neuron (or SMN) is found to have an abnormal area (called a deletion) in over 95 percent of cases of SMA. Symptomatic individuals of all ages can be tested through DNA studies typically done from a blood sample. When both parents are carriers, there is a one in four, or 25 percent, chance, with each pregnancy, to have a child with SMA. Carrier testing for the general population is technically difficult and usually available only if a previously affected child in the family has been studied.

66. A To Z Encyclopedia Topic: Spinal Muscular Atrophy Clinical Services. spinal muscular atrophy. What is spinal muscular atrophy (SMA)? What causes spinal muscular atrophy? SMA is an autosomal recessive disease. http://web1.tch.harvard.edu/cfapps/A2ZtopicDisplay.cfm?Topic=Spinal Muscular Atr

67. The Vest Airway Clearance System - Spinal Muscular Atrophy , Reimbursed by more than 1,100 health plans nationwide. spinal muscular atrophy. Print Version. al. Pulmonary function in spinal muscular atrophy. http://www.thevest.com/conditions/sma/default.asp?gs=patients

68. Spinal Muscular Atrophy Type 3 Information Diseases Database spinal muscular atrophy type 3,KugelbergWelander syndrome, Disease Database Information. spinal muscular atrophy type 3 aka/or Kugelberg-Welander syndrome http://www.diseasesdatabase.com/ddb12315.htm

Diseases Database Index Sponsors Contact ... Previous Page Spinal muscular atrophy type 3 Information Search 2 synonyms or equivalents were found. Spinal muscular atrophy type 3 aka/or Kugelberg-Welander syndrome may cause or feature (Follow link for list) belong(s) to the category of (Follow link for list) No UMLS definitions Spinal muscular atrophy type 3: specific sites Send Spinal muscular atrophy type 3 to medical search engines (JavaScript enabled browsers only) If your browser has no JavaScript you can still use these: Search using Internet medical databases Search using Internet search engines (non-specialist) We subscribe to the HONcode principles of the Health On the Net Foundation i-medicine.info - the evidence based medicine, informatics and audit portal Valid XHTML 1.0 Served 2004-06-03 03:57:00 Metadata Updated 2004-05-22

69. Hereditary Motor Syndromes spinal muscular atrophy 5q. Bulbospinal muscular atrophy (Kennedy s Syndrome; X-linked). l Increased CAG repeats in Androgen Receptor ; Xq12; Recessive http://www.neuro.wustl.edu/neuromuscular/synmot.html

Front Search Index Links ... Patient Info HEREDITARY MOTOR SYNDROMES (SMA, ALS + ...) Hereditary ALS Dominant ALS 1 ALS 3 ... ALS 4 : Senataxin; 9q34 ALS 6 ALS 7 ALS 8 ALS-FTD ... ALS 2 : Alsin; 2q33 ALS 5 X-linked ALS X Childhood-onset ALS : Alsin; 2q33; Recessive : Senataxin; 9q34; Dominant : 15q15; Recessive Other (Type 2) Neurofilament, Heavy subunit Bulbar syndromes AAA syndrome : Aladin; 12q13; Recessive Brown-Vialetto-van Laere : Recessive BSMA: Dominant Bulbar ALS Fazio-Londe : Recessive or Dominant Kennedy's Syndrome (BSMA): Androgen Receptor; Xq12 PLS, Juvenile : Alsin; 2q33; Recessive Worster-Drought Multisystem disorders AAA syndrome : Aladin; 12q13; Recessive : Dominant DDPAC : MAPT; 17q21; Dominant Hexosaminidase A Machado-Joseph : Ataxin-3; 14q32; Dominant Mitochondrial: : Recessive Polyglucosan body disease : GBE1; 3p12; Recessive Spinal muscular atrophy (SMA) : Types SMA : SMN 5q; Recessive Congenital with arthrogryposis Werdnig-Hoffmann Kugelberg-Welander Recessive SMA: Other Spinal muscular atrophy 2 SMA + Congenital fractures SMA + Pontocerebellar hypoplasia Mitochondrial X-linked SMA Bulbo-SMA (Kennedy's) : Androgen Receptor; Xq12

70. Spinal Muscular Atrophy Neuromuscular spinal muscular atrophy (5q). http://www.neuro.wustl.edu/neuromuscular/pathol/sma.htm

SPINAL MUSCULAR ATROPHY (5q) SMA: General pathology SMA, Congenital (Type 0) SMA, Type 1 SMA, Type 2 Also see Spinal muscular atrophy XBSMA pathology SMA 5q: General Features ATPase pH 9.4 stain Grouped atrophy Small muscle fibers are often rounded Pyknotic nuclear clumps are not present. Large muscle fibers are hypertrophied. Large fibers Small fibers : Type I or II SMA, Type 2 Large grouped atrophy Clusters of large type I muscle fibers ATPase, pH 9.4 ATPase, pH 9.4 Small muscle fibers may be varied types (Left) or mostly type II (Right) ATPase, pH 4.3 NADH Many small fibers are type IIC Small fibers stain darkly on NADH SMA, Type 1 Many muscle fibers are small. A few hypertrophied fibers are present SMA, Congenital (Type 0) Only small muscle fibers are present. Small fibers have moderate variation in size Also see: Active Denervation Fiber type grouping Return to Neuromuscular syndromes Return to Neuromuscular home page Return to Hereditary motor syndromes

71. Spinal Muscular Atrophy Print this article. Find related articles By topic Neurology. By keywords Receive HealthLink via email! Subscribe now . spinal muscular atrophy. http://healthlink.mcw.edu/article/921988418.html

Search Articles: search tips Please Take the HealthLink Survey Email this article Print this article Find related articles: By topic: Neurology By keywords: Receive Health Link via email! Subscribe now >> Spinal Muscular Atrophy Spinal muscular atrophy (SMA) is a genetic, motor neuron disease characterized by wasting of the skeletal muscles caused by progressive degeneration of the anterior horn cells of the spinal cord. The disorder causes weakness and atrophy of the voluntary muscles. Weakness occurs more often in the legs than in the arms. There are many types of SMA. Most types, however, are extremely rare, occurring in only one or two families. Some of the more common types are briefly described below. SMA type I , also called Werdnig-Hoffman disease , generally has onset in utero or within the first few months of life. There may be lack of fetal movement in the final months of pregnancy. Symptoms may include hypotonia (diminished muscle tone), weakness, swallowing and feeding difficulties, and respiratory problems. Onset of SMA type II usually occurs between 3 and 15 months of age. Features may include inability to stand or walk, respiratory problems, hypotonia, decreased or absent deep tendon reflexes, and muscle fasciculations (involuntary contractions or twitching of groups of muscles).

72. Spinal Muscular Atrophy - Medical Dictionary Definitions Of Popular Medical Term MedicineNet Home MedTerms medical dictionary AZ List spinal muscular atrophy. Advanced Search. http://www.medterms.com/script/main/art.asp?articlekey=23894

73. Infantile Spinal Muscular Atrophy - Wikipedia, The Free Encyclopedia Infantile spinal muscular atrophy. spinal muscular atrophy is the second most common lethal, autosomal recessive disease in Caucasians. http://en.wikipedia.org/wiki/Infantile_spinal_muscular_atrophy

Infantile spinal muscular atrophy From Wikipedia, the free encyclopedia. Spinal Muscular Atrophies (SMA) are inherited disorders. Spinal muscular atrophy, as defined by international criteria, requires the weakness to be symmetrical and greater in the proximal muscles than in the distal ones. It is when nerves fail to function normally and the muscle cells with which they are connected deteriorate. SMA is when muscles weaken and waste away from degeneration or motor neurons . It is a progressive, symmetrical muscle weakness which usually presents itself within the first six months of life. Death usually occurs between six and twenty months, either of respiratory failure or secondary to chest infection. There are different forms according to age of onset. The forms include: Infantile SMA - Type 1 or Werdnig-Hoffman disease (0-6 months) Intermediate SMA - Type 2 (7-18 months) Adult onset SMA - Type 4 Infantile SMA is the most severe form. Some of the symptoms include: muscle weakness poor muscle tone weak cry limpness or a tendency to flop difficulty sucking or swallowing accumulation of secretions in the lungs or throat the legs tend to be weaker than the arms feeding difficulties increased susceptibility to respiratory tract infections developmental milestones, such as lifting the head or sitting up, can't be reached.

74. Clinical And Molecular Diagnosis Of Spinal Muscular Atrophy. Panigrahi I, Kesari Click on image for details. Year 2002 Volume 50 Issue 2 Page 11722. Clinical and molecular diagnosis of spinal muscular atrophy. http://www.neurologyindia.com/article.asp?issn=0028-3886;year=2002;volume=50;iss

75. SMA Support Inc., Home Of Spinal Muscular Atrophy Dedicated to providing information, support and help for anyone facing the incurable genetic disease spinal muscular atrophy (SMA). http://www.smasupport.com/

Your browser does not support script Welcome to SMA Support! We are an all-volunteer, non-profit, 501(c)(3) tax-exempt organization dedicated to providing information and support to family, friends, individuals and caregivers on all aspects regarding the devastating genetic disease called Spinal Muscular Atrophy. SMA Support Holy Bears Sold HERE SMA Support August Gathering Info HERE Donate Now! Shop Through iGive! "Never doubt that a small group of committed citizens can change the world. Indeed, it is the only thing that ever has." ~Margaret Mead Home SMA Support SMA Info SMA Research ... Contact Us

76. BrainTalk Communities - Spinal Muscular Atrophy Post New Thread. Threads in Forum spinal muscular atrophy, Forum Tools, Search this Forum. Views 3,655 Announcement Donations to http://brain.hastypastry.net/forums/forumdisplay.php?f=238

77. Spinal Muscular Atrophy (MULTILINGUAL) Funding of research, support and networking for families affected by spinal muscular atrophy types I, II, III, adult onset and Kennedy s. http://www.bchealthguide.org/kbase/shc/shc29sma.htm

document.write(''); var hwPrint=1; var hwDocHWID="shc29sma"; var hwDocTitle="Spinal Muscular Atrophy"; var hwRank="1"; var hwSectionHWID="shc29sma"; var hwSectionTitle=""; var hwSource="cn6.0"; var hwProdCfgSerNo="wsh_html_031_s"; var hwDocType="SHC"; Self Help Clearinghouse Spinal Muscular Atrophy Families of S.M.A. (Spinal Muscular Atrophy) International. 22 chapters. Founded 1984. (MULTILINGUAL) Funding of research, support and networking for families affected by spinal muscular atrophy types I, II, III, adult onset and Kennedy's. Educational resources, group development guidelines, quarterly newsletter, pen pals, phone support and videotapes. Online message boards and kids corner support. WRITE: Families of S.M.A. P.O. Box 196 Libertyville, IL 60048-0196 CALL: 1-800-886-1762 FAX: 847-367-7623 E-MAIL: sma@fsma.org WEBSITE: http://www.fsma.org http://www.curesma.com VERIFIED: 5/12/2003 The above information is based upon information available through the "verified" date at the end of each listing. Since American Self-Help Group Clearinghouse's resources are limited; it is not possible to keep every entry in the American Self-Help Group Clearinghouse database completely current and accurate. Please check with the organizations listed for the most current information. For additional information and assistance about self-help groups, please contact the American Self-Help Group Clearinghouse in Cedar Knolls, New Jersey, by email at: info@selfhelpgroups.org

78. WIStv.com Columbia, SC: Health Alert: Spinal Muscular Atrophy Dawn Mercer s Health Alert spinal muscular atrophy, http://www.wistv.com/Global/story.asp?S=1630068

79. SPINAL MUSCULAR ATROPHY : Contact A Family - For Families With Disabled Children printer friendly, spinal muscular atrophy, JENNIFER TRUST FOR spinal muscular atrophy. Jennifer Trust for spinal muscular atrophy Elta http://www.cafamily.org.uk/Direct/s48.html

printer friendly SPINAL MUSCULAR ATROPHY home more about us in your area conditions information ... how you can help search this site Did you find this page helpful? yes no Spinal Muscular Atrophies (SMA) in children are a group of three inheritable neuro-muscular conditions of varying severity in which there is degeneration of the anterior horn cells of the spinal cord with resultant muscular weakness, usually symmetrical. Character-istically, the legs are more severely affected than the arms. Additionally the proximal muscles (those closer to the body) are more severely affected than the distal ones (those closer to the hands and feet). Distinct clinical syndromes can be defined on the basis of the severity of the symptoms displayed. An international classification was agreed in Summer 1990 as follows: Severe SMA - unable to sit unsupported (also known as Werdnig-Hoffmann disease or Type 1) Intermediate SMA - able to sit unsupported, unable to stand or walk unaided (also known as Type 2) Mild SMA - able to stand and walk unaided (also known as Kugelberg-Welander disease or Type 3) Inheritance patterns Autosomal recessive inheritance Prenatal diagnosis The gene for all childhood onset Spinal Muscular Atrophies which maps to chromosome 5, has been identified and named the survival motor neurone (SMN) gene. Mutations in the gene are present in almost all cases, particularly Type 1 and 2, and also provide an accurate means of prenatal diagnosis by chorionic villus sampling during early pregnancy.

80. HealthlinkUSA Spinal Muscular Atrophy Links You can find spinal muscular atrophy right now at Info.com. Click here for page 1 of spinal muscular atrophy information from the HealthlinkUSA directory. http://www.healthlinkusa.com/291ent.htm

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Page 4     61-80 of 110    Back | 1  | 2  | 3  | 4  | 5  | 6  | Next 20