141. Ask NOAH About: Smallpox Ask NOAH About smallpox. smallpox and Anthrax Babies Direct What is smallpox? - KidsHealth Teens and smallpox What is smallpox? http://www.noah-health.org/english/illness/infect/smallpox.html

Ask NOAH About: Smallpox What is Smallpox? Specific Concerns The Basics Transmission and Diagnosis Prevention ... Information Resources What is Smallpox? The Basics Anthrax and Smallpox 101 - ABCNews Frequently Asked Questions and Answers on Smallpox - World Health Organization (also in French and Spanish The New Worry: Smallpox - Time Magazine Smallpox - MEDLINEplus (also in Spanish )(Interactive Flash Presentation) Smallpox - Maryland Department of Health and Mental Hygiene Smallpox - Arizona Department of Health Services Smallpox (Variola) - Utah Department of Health Smallpox: Clinical and Epidemiologic Features - CDC ... WHO Fact Sheet on Smallpox - World Health Organization (also in French and Spanish Transmission and Diagnosis What is Smallpox? - WebMD Smallpox: Contagious, But Not Necessarily Deadly - USA Today Smallpox: Clinical and Epidemiologic Features - CDC Prevention Building a Better Smallpox Vaccine - Time Magazine Detailed Information About Smallpox - National Network for Immunization Information Smallpox Fact Sheet: Caring for the Smallpox Vaccination Site - CDC ... Smallpox Fact Sheet: Information on Live Virus Vaccines and Vaccinia - CDC (also in Spanish Smallpox Fact Sheet: People Who Should NOT Get the Smallpox Vaccine (Unless they are Exposed to the Smallpox Virus) - CDC (also in Spanish Smallpox Fact Sheet: Reactions After Smallpox Vaccination - CDC (also in Spanish Smallpox Fact Sheet: Vaccine Overview - CDC (also in Spanish Smallpox Vaccine - Mayo Health Smallpox Vaccine and Heart Problems: Information for People Who Have Recently Received the Smallpox Vaccine - CDC Someone You Are Close to May Get the Smallpox Vaccine: What You Should Know and Do - CDC (also in

142. CDC Smallpox Vaccine Can Prevent Monkeypox CNN http://cnn.com/2003/HEALTH/06/11/monkeypox.ap/index.html

143. (D2OL)™ - Pathogens - Smallpox smallpox infection was eliminated from the world in 1977. smallpox is caused by the variola virus. The incubation period is about http://www.d2ol.com/smallpox.html

Overview Anthrax Smallpox SARS ... Plague Smallpox infection was eliminated from the world in 1977. Smallpox is caused by the variola virus. The incubation period is about 12 days (range: 7 to 17 days) following exposure. Initial symptoms include high fever, fatigue, and head and back aches. A characteristic rash, most prominent on the face, arms, and legs, follows in 2-3 days. The rash starts with flat red lesions that evolve at the same rate. Lesions become pus-filled and begin to crust early in the second week. Scabs develop and then separate and fall off after about 3-4 weeks. The majority of patients with smallpox recover, but death occurs in up to 30% of cases. Smallpox is spread from one person to another by infected saliva droplets that expose a susceptible person having face-to-face contact with the ill person. Persons with smallpox are most infectious during the first week of illness, because that is when the largest amount of virus is present in saliva. However, some risk of transmission lasts until all scabs have fallen off. Routine vaccination against smallpox ended in 1972. The level of immunity, if any, among persons who were vaccinated before 1972 is uncertain; therefore, these persons are assumed to be susceptible.

144. Edward Jenner Museum Mortality Rates from smallpox in the 18th century smallpox was the most feared and greatest killer of Jenner s time. What is smallpox? http://www.jennermuseum.com/sv/smallpox.shtml

Mortality Rates from Smallpox in the 18th century Smallpox was the most feared and greatest killer of Jenner's time. In today's terms it was as deadly as cancer or heart disease. It killed 10% of the population, rising to 20% in towns and cities where infection spread easily. Among children, it accounted for one-in-three of all deaths. Jenner called it the Speckled Monster. What is Smallpox? Smallpox is caused by the virus variola. It enters the body through the lungs and is carried in the blood to the internal organs, which it infects. The virus then spreads to the skin where it multiplies, causing a rash. Smallpox is characterised by fever, headache, backache and vomiting twelve days after exposure to the virus. The rash appears three days later, beginning as small discrete pink spots which grow bigger and become slightly raised. By the third day these are tense blisters, 6mm in diameter and deep in the skin. These eventually shrink, dry up and fall off, leaving a sunken scar. In severe cases patients die of blood poisoning, secondary infections or internal bleeding. There is no effective treatment once infection has taken place. A Brief History of Smallpox Smallpox is a very ancient disease. The scars on the mummified body of the Pharaoh Rameses V, who died in 1157BC, are believed to have been caused by smallpox. It spread throughout Europe and was carried to the Americas with the voyages of discovery. It killed far more Aztecs and North American Indians than ever died in battles with the white settlers.

145. CNN.com - Smallpox Vaccinations: Weighing The Pros And Cons - Dec. 6, 2002 CNN http://cnn.com/2002/HEALTH/12/06/yh.pul.smallpox/index.html

CNN Europe CNN Asia Languages Spanish Portuguese German Italian Korean Arabic Japanese On CNN TV Transcripts Headline News CNN International ... Special Reports SERVICES Video E-Mail Services CNNtoGO SEARCH Web CNN.com Smallpox vaccinations: Weighing the pros and cons By Dr. Sanjay Gupta CNN Your Health Story Tools (CNN) Many call it the biggest public health decision the country has ever had to make: to vaccinate or not to vaccinate against the smallpox virus. Although the virus has been eradicated for over 20 years, it is believed that stores of the virus still exist in the world today, possibly in Iraq. Under a White House smallpox plan expected to be announced in the next few weeks, about 500,000 health workers and "first responders" would be vaccinated over a period of one to two months. The plus side is that these people would develop immunity within a few days and have protection against the smallpox virus. The down side is the potential side effects. According to health officials, 15 per 1 million people vaccinated would develop life-threatening complications, with one to two people out of every million actually dying from the vaccine. Through voluntary participation in clinical trials, the vaccine would be made available to the public, but the government would only recommend it for health workers and first responders.

146. USATODAY.com - Smallpox Vaccination Plan 'ceased' Less than a year after President Bush announced a smallpox vaccination plan to protect Americans in the event of a terrorist attack, a fraction of the expected http://www.usatoday.com/news/health/2003-10-15-smallpox_x.htm

Cars Jobs Franchises Business Opportunities ... Weather Politics Politics home Politics briefs Latest polls Political calendar Washington Washington home Washington briefs Government Guide Law Center Health Health home Medical resources Health information Editorial/Opinion Ed/Op home Columnists Cartoons More News Top news briefs Nation briefs World briefs States ... Talk Today Posted 10/15/2003 11:41 PM Updated 10/16/2003 11:26 AM Today's Top News Stories Tribunal lawyers say defense short on resources President outlines ideology of war on terror to Air Force graduates Stolen propane trucks in Texas found Reports: Chalabi told Iran that U.S. had broken codes ... Add USATODAY.com headlines to your Web site E-Mail Newsletters Sign up to receive our free Daily Briefing e-newsletter and get the top news of the day in your inbox. E-mail: Select one: HTML Text Breaking News E-Mail Alerts Get breaking news in your inbox as it happens Smallpox vaccination plan 'ceased' By Anita Manning, USA TODAY

147. CNN.com - Surgeon General Vaccinated Against Smallpox - Mar. 11, 2003 CNN http://cnn.com/2003/HEALTH/03/11/smallpox.surgeon.gen.ap/index.html

The Web CNN.com Home Page World U.S. Weather ... Special Reports SERVICES Video E-Mail Services CNNtoGO SEARCH Web CNN.com Surgeon general vaccinated against smallpox Surgeon General Richard Carmona joined other federal health workers Tuesday in getting the smallpox vaccination. Story Tools RELATED Surgeon general to cops: Put down the donuts The vaccine what are the risks? What is smallpox and how does it spread? Bush outlines vaccination plan ... Medical field split on smallpox vaccine WASHINGTON (AP) Surgeon General Richard Carmona got his smallpox vaccination Tuesday, hoping to persuade reluctant health care providers to do the same. The Department of Health and Human Services invited news cameras to watch a public health nurse prick Carmona's arm 15 times as officials worked to build interest in the program. As of last week, just 12,690 people had been vaccinated, far short of the 450,000 people that federal officials had expected. About two dozen members of the Commissioned Corps, a special group of federal health workers, were also vaccinated Tuesday, to help supplement personnel on the state and local level. On Wednesday, Centers for Disease Control and Prevention director Julie Gerberding will be publicly vaccinated in Atlanta, as will Dr. D.A. Henderson, who led the global smallpox eradication campaign.

148. A Dose Of The Pox... smallpox has been known for many centuries. The pox . smallpox first appeared in China and the Far East at least 2000 years ago. http://www.tulane.edu/~dmsander/Tutorials/Pox/Pox1.html

Smallpox: has been known for many centuries. The characteristic "pocks" produced by variola (smallpox) virus gave their name to all forms of infectious disease: "a dose of the pox". Smallpox: first appeared in China and the Far East at least 2000 years ago. The Pharaoh Ramses V died of smallpox in 1157 B.C. Smallpox: reached Europe in 710 A.D. and was transferred to America by Hernando Cortez in 1520. 3,500,000 Aztecs died in the next 2 years. Smallpox: reached plague proportions in the cities of 18th century Europe and was a highly feared scourge. Smallpox: killed five reigning European monarchs during the 18th century. Smallpox: has now been eradicated. The last naturally occurring outbreak was in Somalia on 26th October 1977. How did they do that ? AJC

149. CNN.com - Conn. Smallpox Plan Could Be Revised - Feb. 13, 2003 CNN http://cnn.com/2003/HEALTH/02/13/conn.smallpox.ap/index.html

The Web CNN.com Home Page World U.S. Weather ... Special Reports SERVICES Video E-Mail Services CNNtoGO SEARCH Web CNN.com Conn. smallpox plan could be revised Smallpox vaccinations for health workers began in January in Connecticut. Story Tools RELATED Woman has reaction to smallpox vaccine BRIDGEPORT, Connecticut (AP) Hampered by fewer volunteers than expected, Connecticut is revising its plan to create smallpox response teams in hospitals, an official said Wednesday. The state hoped to vaccinate about 6,000 health care workers and health officials by spring, but early estimates show only 1,000 hospital workers have volunteered, said Christopher Cannon, an organizer of the state's smallpox response plan. That means officials may have to mobilize volunteers from more hospitals than the 32 originally slated to have smallpox response teams, said Cannon. "The good news is that every hospital in the state has agreed to participate," said Cannon, a director at Yale-New Haven Health System's Office of Emergency Preparedness. The number of public health officials who have volunteered for inoculations was not immediately available.

150. The First Recorded Smallpox Vaccination Edward Jenner is renown as the father of smallpox vaccination . Having had smallpox himself as a child, he was immune to the disease. http://www.thedorsetpage.com/history/smallpox/smallpox.htm

Edward Jenner is renown as the "father of smallpox vaccination". Perhaps rightly so, for he dedicated his life, money and reputation to spreading the use of vaccination. In 1774,some twenty years before Jenner first used vaccination on a boy called James Phipps in 1796, at Berkeley in Gloucestershire, a farmer's wife, together with her two sons was vaccinated by her husband at Yetminster in Dorset. In 1774 farmer, Benjamin Jesty was living in Yetminster with his pregnant wife Elizabeth, two sons, Robert and Benjamin aged three and two, and a baby also called Elizabeth. During the spring and summer of that year the highly infectious disease of smallpox raged in the area. Benjamin feared for the health of his wife and family. Having had smallpox himself as a child, he was immune to the disease. In common with many country folk, Benjamin was fully aware of the age-old tradition that people who had earlier caught the mild disease of cowpox did not catch the normally fatal disease of smallpox. At this time, the Jesty’s had two dairymaids, Ann Notley and Mary Reade. Both of these girls had previously had cowpox, and both had nursed family members with smallpox during the current epidemic. I was probably the fact that neither of these girls had caught the disease that decided Benjamin on his subsequent course of action. Benjamin reasoned that if dairymaids who caught cowpox accidentally were immune to smallpox, then someone who caught cowpox deliberately should be equally immune. He therefore resolved to infect his family with cowpox with a procedure that was later to become known as vaccination. The word vaccination derives directly from this connection with cowpox. Vacca is the Latin for cow.

151. Volunteers Prepare For Smallpox Vaccinations CNN http://cnn.com/2003/HEALTH/01/24/smallpox.vaccine.ap/index.html

152. IOM Smallpox Vaccination Program Implementation will provide advice to the Centers for Disease Control and Prevention (CDC) and program managers on selected aspects of preevent smallpox vaccination program http://www.iom.edu/view.asp?id=4781

153. CNN.com - U.S. To Hold Onto Smallpox Stockpiles - November 16, 2001 CNN http://cnn.com/2001/HEALTH/11/16/bush.smallpox/index.html

MAIN PAGE WORLD U.S. WEATHER ... ABOUT US/HELP CNN TV what's on show transcripts CNN Headline News CNN International ... askCNN EDITIONS CNN.com Asia CNN.com Europe CNNenEspanol.com CNNArabic.com ... set your edition Languages Spanish Portuguese German Italian Korean Arabic Japanese Time, Inc. Time.com People Fortune EW InStyle Business 2.0 U.S. to hold onto smallpox stockpiles By Major Garrett CNN White House Correspondent CRAWFORD, Texas (CNN) The Bush administration will retain U.S. stockpiles of the smallpox virus for continued research to deal with a potential attack of a new, weaponized form of the virus, CNN has confirmed. The virus stockpile is under the control of the Centers for Disease Control and Prevention and kept at an undisclosed location. The administration's move reverses a course set two decades ago to eradicate the smallpox virus. The official said the threat of bio-terrorism requires the country to retain the virus stockpiles to prepare for a potential smallpox attack. "This move is a recognition that it's a different climate, a different world," the official said. "Some country could be glad that we have this virus. As you weaponize this stuff, we may have to develop new vaccines to deal with it." The U.S. and Russia have the only known and confirmed stocks of the smallpox virus. But the official said there are concerns that some of Russia's stocks "somehow got loose" and may have fallen into the hands of Iraq, North Korea or a terrorist group such as Al Qaeda.

154. Reportable Infectious Diseases And Conditions idph online home, Illinois Department of Public Health 535 West Jefferson Street Springfield, Illinois 62761 Phone 217782-4977 Fax 217-782-3987 TTY 800-547 http://www.idph.state.il.us/health/infect/reportdis/smallpox.htm

Smallpox Smallpox Frequently Asked Questions Smallpox Cases and Deaths, 1860 - Present Smallpox Information for Health Care Providers Smallpox Information- CDC ... Smallpox Information for Lab and Health Professionals - CDC Illinois Department of Public Health 535 West Jefferson Street Springfield, Illinois 62761 Phone 217-782-4977 Fax 217-782-3987 TTY 800-547-0466 Questions or Comments

155. Study Examines Smallpox Transmission CNN http://cnn.com/2001/HEALTH/conditions/12/17/transmitting.smallpox.ap/index.html

156. Modern History Sourcebook: Lady Mary Wortley Montagu (1689-1762): Smallpox Vacci Back to Modern History SourceBook. Modern History Sourcebook Lady Mary Wortley Montagu (16891762) smallpox Vaccination in Turkey. http://www.fordham.edu/halsall/mod/montagu-smallpox.html

Back to Modern History SourceBook Modern History Sourcebook: Lady Mary Wortley Montagu : Smallpox Vaccination in Turkey In 1717 Lady Montague arrived with her husband, the British ambassador, at the court of the Ottoman Empire. She wrote voluminously of her travels. In this selection she noted that the local practice of deliberately stimulating a mild form of the disease through innoculation conferred immunity. She had the procedure performed on both her children. By the end of the eighteenth century, the English physician Edwardjenner was able to cultivate a serum in cattle, which, when used in human vaccination, eventually led to the worldwide eradication of the illness. Your friend, etc. etc. Source: From Lady Mary Wortley Montagu, Letters of the Right Honourable Lady My Wy Me: Written During her Travels in Europe, Asia and Africa. . . , vol. 1 (Aix: Anthony Henricy, 1796), pp. 167-69; letter 36, to Mrs. S. C. from Adrianople, n.d. This text is part of the Internet Modern History Sourcebook . The Sourcebook is a collection of public domain and copy-permitted texts for introductory level classes in modern European and World history. © Paul Halsall, July 1998

157. CNN.com - Drug Firm To Donate Smallpox Vaccine To U.S. - March 29, 2002 CNN http://cnn.com/2002/HEALTH/03/29/smallpox.vaccine.found/index.html

MAIN PAGE WORLD U.S. WEATHER ... ABOUT US/HELP CNN TV what's on show transcripts CNN Headline News CNN International ... askCNN EDITIONS CNN.com Asia CNN.com Europe CNNenEspanol.com CNNArabic.com ... set your edition Languages Spanish Portuguese German Italian Korean Arabic Japanese Time, Inc. Time.com People Fortune EW InStyle Business 2.0 Drug firm to donate smallpox vaccine to U.S. SWIFTWATER, Pennsylvania (CNN) The drug company Aventis Pasteur will donate to the U.S. government the estimated 85 million to 90 million doses of smallpox vaccine that had been in storage since routine smallpox vaccination ended in 1972, it was announced Friday. Department of Health and Human Services Secretary Tommy Thompson said a formal agreement had not yet been signed, pending the results of testing to determine the vaccine is safe and effective. "This will bolster our emergency smallpox stockpile, provide an extra layer of protection for all Americans in the event of a smallpox outbreak and strengthen our safety net in the event of a biological attack," Thompson said. EXTRA INFORMATION Smallpox Basics He said scientists have been "extremely encouraged by the initial results" of tests on the vaccine, and called the additional vaccines an "insurance policy" until more vaccines are made.

158. Smallpox smallpox Data. smallpox Vaccine Campaign Collapsing. Bush smallpox Plan Takes A Shot. 2 Hospitals Refuse Bush smallpox Vaccination Orders. http://www.rense.com/Datapages/smallpoxdata.htm

Smallpox Data Smallpox Vaccine Campaign Collapsing Bush Smallpox Plan Takes A Shot 2 Hospitals Refuse Bush Smallpox Vaccination Orders Cancer Hospital To Keep Vaccinated Workers 6' From Patients ... Return to Rense.com HomePage

159. CNN.com - Bush 'great' After Smallpox Vaccine - Dec. 22, 2002 CNN http://cnn.com/2002/US/12/22/bush.smallpox/index.html

CNN Europe CNN Asia Languages Spanish Portuguese German Italian Korean Arabic Japanese On CNN TV Transcripts Headline News CNN International ... Special Reports SERVICES Video E-Mail Services CNNtoGO SEARCH Web CNN.com Bush 'great' after smallpox vaccine Bush received the smallpox inoculation Saturday. Story Tools VIDEO CNN's Elizabeth Cohen on the medical debate over smallpox vaccinations (December 12) PLAY VIDEO A look at Israel's smallpox vaccination program PLAY VIDEO RELATED NY faced last U.S. smallpox outbreak The vaccine what are the risks? What is smallpox and how does it spread? Vaccinated people can transmit vaccinia virus ... Smallpox FAQs THE VACCINE: The last natural smallpox case was in Somalia in 1977 Vaccine effective if given within 4 days of exposure Vaccine does not contain the smallpox virus Vaccine is made from a virus called vaccinia 15 per million vaccinated experience serious complications 1-2 people per million will die from vaccine Most Americans under 30 haven't been vaccinated 1 case is considered a public health emergency Source: CDC THE VACCINATION PROGRAM: Vaccinations for about 500,000 troops deployed in high-risk parts of the world began Friday.

160. Smallpox smallpox. smallpox disease. smallpox could occur and spread in any country, and case fatality rates were little altered by therapy. http://edcp.org/html/smallpx.html

EDCP Mission/Vision General Information on Bioterrorism Bioterrorism Information for Health Care Providers Fact Sheets ... ImmuNet Smallpox Table of Contents Center for Immunization Home Page Back Top ... Print Version Links marked with are PDF. Download Adobe Acrobat Reader for viewing .pdf files View this page in German Spanish French Italian Portuguese Family Health Administration Home Site Map Factsheet Index ... Site Use Policies To address technical problems or make suggestions regarding this site send email to: fha_webmaster@dhmh.state.md.us CommunityHealth Administration Last Modified 04/02/2004 12:41:44 PM

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