41. Www.sedirectory.net/Health/Conditions_and_Diseases/Nutrition_and_Metabolism_Diso PDF Ezetimibe Effectively Reduces Plasma Plant Sterols in Patients http://www.sedirectory.net/Health/Conditions_and_Diseases/Nutrition_and_Metaboli

Web Hosting Dir Web Design Dir Search Engine Dir Hardware Info ... Resources Search: Top Health Conditions and Diseases Nutrition and Metabolism Disorders ... Sitosterolemia - A press release with a brief explanation of this disease. Sitosterolemia - An article about this uncommon genetic lipid disorder and the gene that is responsible for it.

42. Circulation -- Abstracts: Salen Et Al. 109 (8): 966 Ezetimibe Effectively Reduces Plasma Plant Sterols in Patients With sitosterolemia. Key Words ezetimibe • sitosterolemia • cholesterol • coronary disease. http://circ.ahajournals.org/cgi/content/abstract/109/8/966

Published online before print February 9, 2004, doi:10.1161/01.CIR.0000116766.31036.03 Full Text of this Article PDF Version of this Article Citation Map Email this article to a friend Similar articles found in: Circulation Online PubMed PubMed Citation Search PubMed for articles by: Salen, G. Alert me when: new articles cite this article Download to Citation Manager Collections under which this article appears: Lipids Cardiovascular Pharmacology Primary prevention All Versions of this Article: (most recent) 01.CIR.0000116766.31036.03v1 Circulation. Clinical Investigation and Reports Ezetimibe Effectively Reduces Plasma Plant Sterols in Patients With Sitosterolemia G. Salen, MD K. von Bergmann, MD P. Kwiterovich, MD J. Kane, MD, PhD S.B. Patel, MD, PhD T. Musliner, MD P. Stein, MD B. Musser, PhD , and the Multicenter Sitosterolemia Study Group From the UMDNJ-New Jersey Medical School, Newark, NJ, and VA Medical Center, East Orange, NJ (G.S.); Department of Clinical Pharmacology, University of Bonn (K.V.B., D.L.), Bonn, Germany; Johns Hopkins University (P.K.), Baltimore, Md; University of California at San Francisco (J.K.), San Francisco, Calif; Medical University of South Carolina (S.B.P.), Charleston, SC; and Merck Research Laboratories (T.M., P.S., B.M.), Rahway, NJ. Reprint requests to Dr Gerald Salen, University of Medicine and Dentistry of New Jersey, 185 S Orange Ave, MSB-H538, Newark, NJ 07103. E-mail

43. ORPHANET - Malattie Rare - Farmaci Orfani Translate this page Annuario, Stampare, MALATTIA Fitosterolemia, Sinonimo(i) sitosterolemia, ICD E78.0, No description is available, MIM 210250, Tipo(i) di consulenze necessarie. http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=IT&Expert=2882

44. SearchBug Directory: Health: Conditions_and_Diseases: Nutrition_and_Metabolism_D Open Directory. Search sitosterolemia, sitosterolemia http//www.musc.edu/frd/P200047ncs.htm A press release with a brief explanation of this disease. http://www.searchbug.com/directory.aspx/Health/Conditions_and_Diseases/Nutrition

All Searches Auctions CompanyFinder Entertainment ... Travel Search the Web: Web Images Audio Files News Multimedia Shopping Open Directory Search: Featured Websites Sitosterolemia Health Forums - esupportgroups.com Ask questions and chat with others on our health and wellness fourms. Sitosterolemia Health Conditions and Diseases Nutrition and Metabolism Disorders Cholesterol and Other Fats ... Go to Directory Home Web Pages - ranked by popularity Sitosterolemia http://www.musc.edu/frd/P200047ncs.htm A press release with a brief explanation of this disease. Sitosterolemia http://www.intelihealth.com/ipn/pcn/HN/s_r/00196749.htm An article about this uncommon genetic lipid disorder and the gene that is responsible for it. Help build the largest human-edited directory on the web. Submit a Site Update URL Open Directory Project Become an Editor ... Report a Problem 2004, SearchBug.com, LLC About Us Contact Us Help Privacy ... WebMail

45. Title Macrophage 3hydroxy-3-methylglutaryl coenzyme A reductase activity in sitosterolemia effects of increased cellular cholesterol and sitosterol concentrations. http://www.ncl.ac.uk/medplant/about_mprc/My Webs/principals/sitosterols/sitoster

Title Macrophage 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in sitosterolemia: effects of increased cellular cholesterol and sitosterol concentrations. Author Nguyen, Lien B.; Salen, Gerald; Shefer, Sarah; Tint, G. Stephen; Ruiz, Frank. Place Department of Medicine, Division of Gastroenterology and Liver Center, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA. Source Metabolism, Clinical and Experimental CODEN: METAAJ ISSN Journal written in English. Abstract Sitosterolemia is a rare, recessively inherited disease characterized clin. by accelerated atherosclerosis and xanthomas and biochem. by hyperabsorption and retention of sitosterol and other plant sterols in tissues. Decreased cholesterol biosynthesis and inhibition of 3-hydroxy-3-methylgluratyl CoA (HMG-CoA) reductase and other enzymes in the biosynthetic pathway have been assocd. with enhanced low-d. lipoprotein (LDL) receptor function. We examd. the effects of cholesterol and sitosterol on sterol concns. and compn.

46. Sitosterolemia Syndrome. sitosterolemia. sitosterolemia http//www.musc.edu A press release with a brief explanation of this disease. sitosterolemia http://www.medlina.com/sitosterolemia.htm

100 Hot Books 100 Hot CDs 100 Hot Videos 100 Hot DVDs ... Women's Health T he Web MEDLINA.com CDC WHO FDA NIH Search: All Products Books Magazines Popular Music Classical Music Video DVD Baby Electronics Software Outdoor Living Wireless Phones Keywords: CATEGORIES Home Up Selective Mutism Shwachman-Diamond Syndrome Sitosterolemia Smith Lemli Opitz Syndrome Smith-Magenis Syndrome Stickler Syndrome Sitosterolemia Sitosterolemia - http://www.musc.edu A press release with a brief explanation of this disease. Sitosterolemia - http://www.intelihealth.com An article about this uncommon genetic lipid disorder and the gene that is responsible for it. Scientists Closer To Locating Gene That May Explain Cholesterol Absorption - http://news.medscape.com An article about a study of 10 families with sitosterolemia, a rare, recessively inherited disease. SUBCATEGORIES Up Search Now: info@medlina.com N ew Y ork C ity A merica M edica, I nc.

47. SIERE (Sistema De Información Sobre Enfermedades Raras En Español) Translate this page La sitosterolemia es una enfermedad extremadamente rara del metabolismo de los lípidos, caracterizada por el desarrollo de aterosclerosis (engrosamiento http://cisat.isciii.es/er/prg/er_bus2.asp?cod_enf=2953

48. Investigating Cholesterol Investigating cholesterol. Scientists identify genes linked to sitosterolemia; study finds influence of familial traits on response to diet. http://www.genomenewsnetwork.org/articles/01_01/Sitosterolemia.shtml

Home About Topics Subscribe Investigating cholesterol Scientists identify genes linked to sitosterolemia; study finds influence of familial traits on response to diet By Edward R. Winstead January 16, 2001 Two groups of researchers have identified genes that may cause sitosterolemia, an uncommon genetic cholesterol disorder. The disorder is due to defects in cells that distinguish and selectively eliminate different types of dietary cholesterol. Sitosterolemia patients have elevated levels of cholesterol in blood and accumulate plant 'sterols' in tissues, putting them at risk for heart disease at an early age. (The primary plant sterol is sitosterol; hence the name, sitosterolemia.) Shailendra B. Patel, of the Medical University of South Carolina, in Charleston, and colleagues report this month that nine unrelated individuals with sitosterolemia have defects in the gene. Patel's group hypothesizes that the gene is important in the regulation of cholesterol absorption, a process that has long been a mystery in the lipid metabolism field. The findings appear in

49. Sitosterolemia From Linkspider UK Health Directory sitosterolemia by Linkspider UK, sitosterolemia links and sitosterolemia topics from our Health directory. Directory Topic sitosterolemia assoicated to Health. http://linkspider.co.uk/Health/ConditionsandDiseases/NutritionandMetabolismDisor

Match » -All words -Any word -Exact text Search » The Web Jobs / Vacancy Images / Photos FTP / Downloads United Kingdom United States of America Argentina Austria Australia Bangladesh Belgium Bolivia Brazil Bulgaria Canada Chile China Cuba Cyprus Czech Republic Czechoslovakia Denmark Dominican Republic Ecuador Egypt Estonia Finland France Germany Ghana Greece Hong Kong Hungary Iceland India Indonesia Ireland Israel Italy Japan Jordan Kenya Kuwait Latvia Lithuania Luxembourg Malaysia Malta Mexico Moldavia Monaco Morocco Mozambique Nepal Netherlands New Zealand Nicaragua Nigeria North Korea Norway Pakistan Panama Paraguay Peru Philippines Poland Portugal Qatar Romania Russian Federation Saudi Arabia Singapore South Africa South Korea Spain Sri Lanka Sweden Switzerland Taiwan Tanzania Thailand Tunisia Turkey Ukraine United Arab Emirates Uruguay Venezuela Yemen Yugoslavia Zambia Zimbabwe Ranking » On (no duplicate) Off (allow duplicate) Add my Site Toolbar Affiliates Directory Topic Sitosterolemia assoicated to Health Directory Tree: Top Health Conditions and Diseases Nutrition and Metabolism Disorders ... Cholesterol and Other Fats : Sitosterolemia ( Sitosterolemia - A press release with a brief explanation of this disease.

50. Complete List Of Candidates Associated To Sitosterolemia Complete list of candidates associated to sitosterolemia, G2D Home. The graph represents the BLASTX hits found in the region and the http://www.bork.embl-heidelberg.de/g2d/list_hits_disease.pl?U50954:Sitosterolemi

51. References For Sitosterolemia With The MeSH Term Coronary Disease References for sitosterolemia with the MeSH term Coronary Disease, G2D Home. PMID and date. Follow the link to see the corresponding entry by PubMed http://www.bork.embl-heidelberg.de/g2d/exam_mesh_disease.pl?Coronary_Disease:U50

52. A Mouse Model Of Sitosterolemia: Absence Of Abcg8/sterolin-2 Results In Failure BMC Med. 2004; 2 (1) 5 A mouse model of sitosterolemia absence of Abcg8/sterolin2 results in failure to secrete biliary cholesterol. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=394351&rendertype=abst

53. B-Sitosterolemia And Xanthomatosis A NEWLY DESCRIBED LIPID STORAGE DISEASE IN TW Invest. 1974 April; 53 (4) 1033 1043 bsitosterolemia and Xanthomatosis. A NEWLY DESCRIBED LIPID STORAGE DISEASE IN TWO SISTERS. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=333088

54. DEF MEXICO Translate this page sitosterolemia homocigótica (fitosterolemia). ZIENT Ò está indicada para disminuir las concentraciones elevadas de sitosteroles http://www.facmed.unam.mx/bmnd/plm/mex/productos/ZIENT.htm

NOMBRE COMERCIAL Y GENÉRICO: ZIENT (Ezetimiba) Tabletas 2. FORMA FARMACÉUTICA Y FORMULACIÓN: Cada tableta contiene: Ezetimiba mg Excipiente cbp tableta ZIENT (Ezetimiba) pertenece a una nueva clase de compuestos reductores de los lípidos que inhiben selectivamente la absorción intestinal de colesterol y de esteroles vegetales relacionados con él. El nombre químico de ZIENT (Ezetimiba) es 1-(4-fluorofenil)-3(R )[3-(4-fluorofenil)-3(S)-hidroxipropil]-4(S)-(4-hidroxifenil)-2-acetidinona. Su fórmula empírica es C H F NO , tiene un peso molecular de 409.4, y su fórmula estructural es: La Ezetimiba es un polvo cristalino blanco, libremente soluble a muy soluble en etanol, metanol y acetona e insoluble en agua. Tiene un punto de fusión de unos 163°C, y es estable a la temperatura ambiente Ingredientes activos: Cada tableta de ZIENT para administración por vía oral contiene 10 mg de Ezetimiba. Ingredientes inactivos: Cada tableta con 10 mg contiene croscarmelosa, monohidrato de lactosa, estearato de magnesio, celulosa microcristalina, polividona y laurilsulfato de sodio. 3. INDICACIONES TERAPÉUTICAS:

55. DEF MEXICO Translate this page sitosterolemia homocigótica (fitosterolemia) EZETROL está indicado para disminuir las concentraciones elevadas de sitosteroles y de campesterol en los http://www.facmed.unam.mx/bmnd/plm/mex/productos/9674.htm

INFORMACIÓN NUEVA Ezetrol Comprimidos (Ezetimiba) FORMA FARMACÉUTICA Y FORMULACIÓN: EZETROL (ezetimiba) pertenece a una nueva clase de compuestos reductores de los lípidos que inhiben selectivamente la absorción intestinal de colesterol y de esteroles vegetales relacionados con él. El nombre químico de EZETROL (ezetimiba) es 1-(4 fluorofenil)-3(R)-[3-(4-fluorofenil)-3(S)-hidroxipropil]-4(S)-(4-hidroxifenil)-2-acetidinona. Su fórmula empírica es C H F NO , tiene un peso molecular de 409.4, y su fórmula estructural es: La ezetimiba es un polvo cristalino blanco, libremente soluble a muy soluble en etanol, metanol y acetona e insoluble en agua. Tiene un punto de fusión de unos 163°C, y es estable a la temperatura ambiente. Ingredientes activos: Cada comprimido de EZETROL para administración por vía oral contiene 10 mg de ezetimiba. Ingredientes inactivos: Cada comprimido con 10 mg contiene croscarmelosa, monohidrato de lactosa, estearato de magnesio, celulosa microcristalina, povidona y laurilsulfato de sodio. INDICACIONES TERAPÉUTICAS: Hipercolesterolemia primaria: Administrado con un inhibidor de la reductasa de la HMG-CoA (estatina) o solo

56. NFI - Rapport For Prosjekter sitosterolemi. Studies of ABCG5 and ABCG8; the genes mutated in the autosomal recessive lipid disorder sitosterolemia. Prosjektsammendrag http://dbh.nsd.uib.no/nfi/rapport/?Keys=22125&language=no

57. NFI - Project Report Studies of ABCG5 and ABCG8; the genes mutated in the autosomal recessive lipid disorder sitosterolemia. Studier av ABCG5 og ABCG8 http://dbh.nsd.uib.no/nfi/rapport/?keys=22125&language=en

58. HEALTHMEDNET ILLNESS DISEASE URL DIRECTORY 26476, sitosterolemia, http//directory.ansme.com/health/168.html, sitosterolemia, http//www.e88.com/health_conditions, sitosterolemia (3 http://www.healthmednet.com/SIR-SPAN.htm

SIR - SPAN Sirenomelia Sequence http://my.webmd.com/content/healthwise/30/7398 Sirenomelia Sequence http://www.rarediseases.org/search/rdblist.html Sirenomelia Sequence [nord] http://content.health.msn.com/content/healthwise/106/26476 Sirenomelus http://my.webmd.com/content/healthwise/30/7398 Sirenomelus [nord] http://content.health.msn.com/content/healthwise/106/26476 siriasis http://www.healthanswers.com/patco/videos_main.asp Sites http://www.medwebplus.com/subject/Diseases_and_Conditions Siti http://my.webmd.com/content/healthwise/30/7398 Siti [nord] http://content.health.msn.com/content/healthwise/106/26476 Sitosterolemia http://directory.ansme.com/health/168.html Sitosterolemia http://www.e88.com/health_conditions Sitosterolemia (3) http://directory.google.co.nz/Top/Health/Conditions_and_Diseases Sitosterolemia@ http://dmoz.org/Health/Conditions_and_Diseases/ Sitosterolemia@ (3) Situs Inversus http://www.hon.ch/cgi-bin/HONselect?browse+C16.131 Situs Inversus, Bronchiectasis and Sinusitis http://my.webmd.com/content/healthwise/30/7398 Situs Inversus, Bronchiectasis and Sinusitis [nord] http://content.health.msn.com/content/healthwise/106/26476

59. Entry Page Tian,H.; Graf,GA; Yu,L.; Grishin,NV; Schultz,J.; Kwiterovich,P.; Shan,B.; Barnes,R.; Hobbs,HH; Accumulation of dietary cholesterol in sitosterolemia caused by http://srs.csc.fi/srs7bin/cgi-bin/wgetz?-id 7BJS21N_LJL -e [SWISSPROTRELEASE:'AB

60. Sitosterolemia 12.1 Familiaalinen hyperkolesterolemia, FHtauti. M. Salo 16.8.96 Lastenendokrinologien syyskokous, Pirkkala LDL-reseptorimutaatio; http://www.lastenendo.sci.fi/luku92/921.html

12.1 Familiaalinen hyperkolesterolemia, FH-tauti M. Salo 16.8.96 Lastenendokrinologien syyskokous, Pirkkala LDL-reseptorimutaatio Kromosomi 19 AD homotsygootteja 1: 1 milj (Suomessa 3) heterotsygootteja 1: 500 (USA, UK, N, DK, J) (1:67 ja 1:100 E-Afrikan Ashk-juut ja afrikaan) Suomessa 10 000? Mutaatiot: yli 150 kuvattu Suomessa: 4 yleistä (75%) FH-Helsinki del ex 16-18 (Aalto-Setälä 1988) FH-North-Karelia del nt 925-931 (Koivisto 92) harvinaista (yht. 85%) FH-Oulu-1, FH-Oulu-2, FH-Jalasjärvi ym. 2 lievää (FH-Espoo ja -Keuruu) mutaatio vaikuttaa taudinkuvaan Kliininen kuva S-Kol heterotsyg 6 - 15 mmol/l homotsyg 16 - 26 mmol/l HDL-K Trigly normaali Ksantoomiat, ksantelasmat Ateroskleroosi, angio+ Sepelvaltimotauti Homotsygootti: vanhin elänyt 57v, muutama äiti synnyttänyt FH:n diagnoosi A. lapsen S-Kol 7.0, LDL-Kol 5.0 mmol/l ja S-Trigly N ja sekundaariset hyperlipidemiat poissuljettu sekä jompikumpi B. Yhdellä tai useammalla 1 sukulaisella FH Yhdellä tai useammalla 1 sukulaisella tyyppi IIa hyperlipidemia, ksantoomia ja / tai varhainen SVT

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