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         Sarcoidosis:     more books (100)
  1. Sarcoidosis: An entry from Gale's <i>Gale Encyclopedia of Medicine, 3rd ed.</i> by Rosalyn, MD Carson-DeWitt, 2006
  2. The Official Patient's Sourcebook on Sarcoidosis --2002 publication. by Icon Health Publications, 2002-01-01
  3. Small Fiber Neuropathy: A Novel Finding in Sarcoidosis by Elske Hoitsma, 2005
  4. Sarcoidosis often requires many visits before diagnosis is clinched. (Pulmonary Symptoms Confound).: An article from: Skin & Allergy News by Miriam E. Tucker, 2003-04-01
  5. Cutaneous manifestations of systemic disease: sarcoidosis, GVHD, behcet's disease, and pyoderma gangrenosum.(Dermatology Nursing Essentials: Core Knowledge)(Author ... An article from: Dermatology Nursing by Sue Ann McCann, 2007-02-01
  6. Renal failure and hypercalcemia as initial manifestations of extrapulmonary sarcoidosis.(Case Report): An article from: Southern Medical Journal by Carlos Ponce, Jaspal S. Gujral, 2004-06-01
  7. Sarcoidosis. Clinics in Chest Medicine. Volume 18. Number 4. December 1997 by Om P. Sharma, 1997
  8. Glioblastoma multiforme disguised as sarcoidosis: pitfalls in diagnosis.(Letter to the editor): An article from: Southern Medical Journal by Bobbak Vahid, Sandra Weibel, 2007-03-01
  9. Pulmonary sarcoidosis presenting with acute respiratory failure.(Case Report): An article from: Southern Medical Journal by Naricha Chirakalwasan, Mohammed M. Dallal, 2005-03-01
  10. Sarcoidosis imitates other skin disorders in blacks.(Skin Disorders): An article from: Family Practice News by Michele G. Sullivan, 2005-05-01
  11. Coexistence of sarcoidosis and malignancy.(Case Report): An article from: Southern Medical Journal by William E. Caras, Thomas Dillard, et all 2003-09-01
  12. Sarcoidosis presenting as a solitary parotid mass.(Case study): An article from: Ear, Nose and Throat Journal by James T. McCormick, E. Douglas Newton, et all 2006-10-01
  13. Tenth International Conference on Sarcoidosis and Other Granulomatous Disorders (Annals of the New York Academy of Sciences, Vol 465)
  14. Tenth International Conference on Sarcoidosis and Other Granulomatous Disorders (Annals of the New York Academy of Sciences)

61. Sarcoidosis
In the Spotlight. June 27, 2000. So, What s sarcoidosis? What Is sarcoidosis? sarcoidosis is a multiorgan system disease with no known cause.
http://www.personalmd.com/news/sarcoidosis_062700.shtml
Home Noticias de Salud Family Centers Health Centers ... My Health Manager Search PersonalMD Services Family Health Women's Health Children's Health ... Health Encyclopedia
In the Spotlight
June 27, 2000 So, What's Sarcoidosis? By Nick Shah, MD
Kenneth Song, MD

Personal MD.com Medical Contributors
What Is Sarcoidosis?
Sarcoidosis is a multi-organ system disease with no known cause. It commonly affects the lungs, skin, eye and lymph nodes where the abnormal tissue development is seen in multiple areas.
In U.S., the disease is commonly seen in the African- American women and between the ages of 20 and 40. There have also been cases affecting the elderly and children as well. The number of cases in the U.S. is estimated to be 10 to 40 per 100,000 people.
How Does It Occur?
Although the triggers for sarcoidosis are not yet known, scientists have figured out that the disease process is a result of abnormal white blood cell activation leading to a formation of granulomas in the tissues.
Granulomas are mostly collections of white blood cells and epithelial cells (cells that cover organ surfaces). When enough granulomas are formed within an organ, they may alter the normal architecture of the organ, causing the organ to function improperly.
What Are The Symptoms?

62. SARCOIDOSIS-Medfacts-National Jewish Medical And Research Center
Signs and Symptoms of sarcoidosis MedFact From National Jewish Medical and Research Center 1 Respiratory Hospital in America. sarcoidosis.
http://www.nationaljewish.org/medfacts/sarcoid.html
SARCOIDOSIS
Sarcoidosis is a disease that occurs when areas of inflammation develop in different organs of the body. Very small clusters of inflammation, called granulomas, are seen with sarcoidosis. They may occur in the lungs, lymph nodes, eyes, skin or any area of the body. These granulomas may clear up on their own or cause permanent scarring. The cause of sarcoidosis is unknown. Sarcoidosis occurs more often in Caucasians of European descent and in African-Americans. About 10 to 40 out of every 100,000 people develop sarcoidosis. It is most common in young people between the ages of 20 and 40. Sarcoidosis is not contagious.
What are the signs and symptoms?
People with sarcoidosis may have no symptoms, only vague symptoms of a general nature such as weight loss and fever, or symptoms associated with a specific organ, usually the lungs. More than one organ can be involved. Up to half of people with sarcoidosis have no symptoms when the illness is diagnosed. Thus, the diagnosis can be difficult to make. Signs and symptoms associated with specific organ involvement can include the following: Lungs
Inflammation in the lungs can cause shortness of breath, wheezing or cough (often a dry cough). In some people, the symptoms go away; in others there can be permanent scarring.

63. Sarcoidosis
sarcoidosis Diseases We Treat at National Jewish Medical and Research Center 1 Respiratory Hospital in America. Search our website, sarcoidosis.
http://www.nationaljewish.org/diseases/dt12.html
Sarcoidosis
Sarcoidosis Program Sarcoidosis MedFacts Scientific Journal Articles Sarcoidosis Research Feel free to call the LungLine at 1-800-222-LUNG to talk with a registered nurse about your sarcoidosis care.
National Jewish has a Sarcoidosis Clinic that offers evaluation and treatment of this lung disease. Our specialists are involved in clinical research studies that are looking at the causes and at treatment of Sarcoidosis.
Dedicated to care and discovery. Since 1899.
Ranked the #1 Respiratory Hospital in America for 6 consecutive years
U.S. News and World Report Home Contact Glossary Businesses/Sponsors ... Laboratory Services

64. Handbook Of Ocular Disease Management - Sarcoidosis
sarcoidosis. SIGNS AND SYMPTOMS sarcoidosis is a systemic granulomatous disease of unknown etiology. Clinical findings may include
http://www.revoptom.com/handbook/sect7d.htm
SARCOIDOSIS SIGNS AND SYMPTOMS
Sarcoidosis is a systemic granulomatous disease of unknown etiology. Clinical findings may include a debilitating, febrile illness with cough and dyspnea, fatigue, bilateral hilar lymphadenopathy (visible upon plain film radiograph), erythema nodosum, alveolitis, acute polymyositis, arthritis, musculoskeletal anomalies, lacrimal or salivary gland infiltration or sarcoid nodules of the skin. It occurs most frequently in young adults (20 to 40 years), has a predilection for women and for races of color. Patients diagnosed with systemic sarcoidosis have nearly 20 percent incidence of ocular involvement. The most prevalent ocular sign is unilateral, anterior, granulomatous uveitis. Less common presentations include unilateral nongranulomatous uveitis, bilateral intermediate uveitis, and bilateral chronically smoldering low-grade granulomatous ocular inflammation (Lofgren's syndrome). The common clinical ocular findings associated with sarcoid uveitis include decreased or hazy vision, pain, photophobia, lacrimation, conjunctival injection, cells and flare in the anterior chamber, granulomatous iritis with large "mutton fat" keratic precipitates scattered over the back surface of the corneal endothelium, iritis spill over leading to anterior vitritis, true vitritis with white exudative debris in the region of the ora serrata (snowball or snowbank retinopathy) with retinal vasculitis (candle wax drippings) and phlebitis (venous sheathing).

65. From The Grand Rounds Archive At Baylor
OTOLARYNGOLOGIC MANIFESTATIONS OF sarcoidosis March 9, 1995 Andrew L. de Jong, MD. By definition, sarcoidosis is a systemic disease.
http://www.bcm.tmc.edu/oto/grand/3995.html
Grand Rounds Archives
The information contained within the Grand Rounds Archive is intended for use by doctors and other health care professionals. These documents were prepared by resident physicians for presentation and discussion at a conference held at The Baylor College of Medicine in Houston, Texas. No guarantees are made with respect to accuracy or timeliness of this material. This material should not be used as a basis for treatment decisions, and is not a substitute for professional consultation and/or peer-reviewed medical literature. OTOLARYNGOLOGIC MANIFESTATIONS OF SARCOIDOSIS
March 9, 1995
Andrew L. de Jong, M.D. Historically, Hutchinson is credited with first describing the disease and he named it "Mortimers malady" after the patient, Mrs. Mortimer, who had the unique skin findings. In 1899, Boeck described the skin manifestations in more detail and called the disease Boeck's sarcoidosis. He used sarcoid in the name because he thought it was cutaneous form of a sarcoma. The Danish ophthalmologist, Heerfordt, described the triad of uveitis, parotid enlargement, and cranial nerve paresis in 1909. Schaumann described the pathologic findings in 1916 and then, in 1940, Poe was the first to pathologically document sarcoid involvement in the larynx. Finally, Kvein and Siltzbach refined a skin test for sarcoidosis using a heat killed suspension from the lymph nodes of known sarcoid patients. Neurologic symptoms occur in only 5% of the cases, but they are the most common reason for otolaryngologic consultation. Facial nerve palsies are the most common cranial nerve deficit but any cranial nerve can be affected. The paresis can either be fluctuating or a relentless, progressive course. Although Heerfordt's disease most often includes facial nerve paresis, any cranial nerve can be affected in association with uveitis and parotid enlargement. Fever is also commonly associated with this constellation of findings.

66. Grand Rounds Archives
OTOLARYNGOLOGIC MANIFESTATIONS OF sarcoidosis J. Cary Moorhead, MD, MD January 11, 1992. The mainstay of treatment for sarcoidosis is corticosteroids.
http://www.bcm.tmc.edu/oto/grand/11192.html
Grand Rounds Archives
The information contained within the Grand Rounds Archive is intended for use by doctors and other health care professionals. These documents were prepared by resident physicians for presentation and discussion at a conference held at The Baylor College of Medicine in Houston, Texas. No guarantees are made with respect to accuracy or timeliness of this material. This material should not be used as a basis for treatment decisions, and is not a substitute for professional consultation and/or peer-reviewed medical literature. OTOLARYNGOLOGIC MANIFESTATIONS OF SARCOIDOSIS
J. Cary Moorhead, M.D, MD
January 11, 1992 Sarcoidosis is a chronic, systemic granulomatous disease of unknown etiology. It generally affects people in their 20s to 40s and has a predilection for females, Blacks and Puerto Ricans. Worldwide, there is an increased prevalence of sarcoidosis in northern Europe, the southeastern United States, Australia, and Scandinavia. The etiology of sarcoidosis remains a mystery despite a great deal of research. An air-borne pathogen has been speculated, although a specific entity has never been identified. The immunologic response is probably initiated when an unknown antigen acts on a mononuclear phagocyte or T-helper cell, activating the T-helper cell to secrete Interleukin 2. This leads to further proliferation of the T-helper cells as well as secretion of a monocyte chemotactic factor responsible for recruiting the cellular building blocks needed for granuloma formation.

67. Sarcoidosis
sarcoidosis. This page has moved to. http//www.healthynj.org/discon/sarcoid/main.htm. at HealthyNJ.
http://www4.umdnj.edu/camlbweb/sarcoidosis.html
Sarcoidosis This page has moved to http://www.healthynj.org/dis-con/sarcoid/main.htm at HealthyNJ

68. Sarcoidosis - Arthritis: Health And Medical Information About Arthritis And Othe
What is sarcoidosis? sarcoidosis is a disease that results from inflammation of tissues of the body. The cause of sarcoidosis is unknown.
http://www.medicinenet.com/Sarcoidosis/article.htm
MedicineNet Home Arthritis Home > Sarcoidosis Advanced Search
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Sarcoidosis
What is sarcoidosis? Sarcoidosis is a disease that results from inflammation of tissues of the body. It can appear in almost any body organ, but most often starts in the lungs or lymph nodes. The cause of sarcoidosis is unknown. The disease can appear suddenly and disappear. Or it can develop gradually and go on to produce symptoms that come and go, sometimes for a lifetime. As sarcoidosis progresses, small lumps, or granulomas, appear in the affected tissues. In the majority of cases, these granulomas clear up, either with or without treatment. In the few cases where the granulomas do not heal and disappear, the tissues tend to remain inflamed and become scarred (fibrotic). Sarcoidosis was first identified over 100 years ago by two dermatologists working independently, Dr. Jonathan Hutchinson in England and Dr. Caesar Boeck in Norway. Sarcoidosis was originally called Hutchinson's disease or Boeck's disease. Dr. Boeck went on to fashion today's name for the disease from the Greek words "sark" and "oid," meaning flesh-like. The term describes the skin eruptions that are frequently caused by the illness.

69. Sarcoidosis - Wikipedia, The Free Encyclopedia
sarcoidosis. From Wikipedia, the free encyclopedia. sarcoidosis is an uncommon autoimmune disorder of unknown cause that primarily affects younger individuals.
http://en.wikipedia.org/wiki/Sarcoidosis
Sarcoidosis
From Wikipedia, the free encyclopedia.
Sarcoidosis is an uncommon autoimmune disorder of unknown cause that primarily affects younger individuals. The disease is characterised by the presence of non-caseating granulomas which can appear almost anywhere in the body but usually appear in either the lungs or the lymph nodes . It can occasionally appear suddenly but more often than not appears gradually. Sarcoidosis can sometimes have the appearance of tuberculosis Sarcoidosis is more commonly seen in blacks than whites. Pulmonary ( lung ) involvement is the most common presentation of sarcoidosis. Sarcoidosis is a restrictive disease of the lungs, causing a decrease in lung volume and decreased compliance (the ability to stretch). The vital capacity (full breath in, to full breath out) is decreased, and most of this air can be blown out in the first second. This means the FEV /FVC ratio is increased from the normal of about 80%, to 90%. Treatment is generally with corticosteroids , although the use of corticosteroids in mild disease has been the subject of mounting doubt. Severe disease is treated with steroids, and later with steroid-sparing agents This article is a stub . You can help Wikipedia by expanding it Views Personal tools Navigation Search Toolbox

70. Therapy For Sarcoidosis Of Lungs And Thoracic Lymphatic Nodes
Treatment. Therapy for sarcoidosis of Lungs and Thoracic Lymphatic Nodes. Therapy for sarcoidosis of Lungs and Thoracic Lymphatic Nodes. sarcoidosis
http://infoventures.com/emf/currlit/bu11820.html
[ EMF-Link Home
Hot Topics. Use of Electromagnetic Fields in Patient Treatment.
Therapy for Sarcoidosis of Lungs and Thoracic Lymphatic Nodes.
Last modified on: Friday, January 16, 2004 10:32:29
Therapy for Sarcoidosis of Lungs and Thoracic Lymphatic Nodes.
Sarcoidosis is a systemic disease characterized by formation of specific epithelioid granulomas in various tissues and organs. Sarcoidosis is thought to be caused by modified tuberculosis mycobacteria (granular or L-forms). The disease usually has a chronic course with numerous recurrences (relapses). Conventional methods of therapy (corticosteroids, vitamins, antioxidants) are ineffective. Based on favorable results of millimeter wave (MW) therapy in tuberculosis patients demonstrated previously, a Russian research group tested the method in 60 patients with sarcoidosis and also obtained favorable results. The authors emphasize that the ability of MW therapy to provoke resolution of granulomas (instead of fibrosis, which commonly takes place under conventional treatment) is extremely important for restoration of function in the impaired organs. [BENER READER COMMENTS Jan - Mar, 2002

71. The Leading Lung Disease Site On The Net
sarcoidosis.net, HEALTH CATEGORIES By clicking, you agree to our Term and Conditions. sarcoidosis.net is undergoing further development.
http://www.sarcoidosis.net/
This page requires frames.

72. HealthlinkUSA Sarcoidosis Links
FindWhat. You can find sarcoidosis right now at Info.com. Kanoodle.com. Click here for page 1 of sarcoidosis information from the HealthlinkUSA directory.
http://www.healthlinkusa.com/271ent.htm

73. Sarcoidosis Associated With Recurrent Pancreatitis
sarcoidosis Associated With Recurrent Pancreatitis AJIT P. LIMAYE, MD, DOUGLAS S. PAAUW, MD, GANESH RAGHU, MD, RODNEY A. SCHMIDT, MD, PhD, and W. CONRAD LILES
http://www.sma.org/smj/97apr15.htm
Sarcoidosis Associated With Recurrent Pancreatitis
AJIT P. LIMAYE, MD, DOUGLAS S. PAAUW, MD, GANESH RAGHU, MD,
RODNEY A. SCHMIDT, MD, PhD, and W. CONRAD LILES, MD, PhD, Seattle, Wash
ABSTRACT: A 56-year-old previously healthy man had two episodes of unexplained pancreatitis in the setting of constitutional symptoms, recurrent palsy of the right seventh cranial nerve, and bilateral parotitis. Chest radiography revealed marked bilateral hilar lymphadenopathy, and sarcoidosis was diagnosed by bronchoscopy with transbronchial biopsy showing noncaseating granulomas. The pancreatitis and sarcoidosis responded to corticosteroid therapy but recurred after corticosteroid dosage was reduced. Retreatment with a higher dosage of corticosteroids led to resolution of pancreatitis; 3 months later, the patient remained well and without further recurrence of pancreatitis while taking the higher dose of corticosteroids. Clinically significant pancreatitis should be included as an unusual manifestation of sarcoidosis, and corticosteroid therapy should be considered in the management of pancreatitis associated with sarcoidosis. SARCOIDOSIS is a granulomatous disease of unknown etiology that can involve almost any organ. The most commonly involved organs in the gastrointestinal system are the liver and spleen, with sporadic reports of involvement of the stomach, esophagus, small bowel, and colon.1 Although previous autopsy series of patients with sarcoidosis have documented granulomatous involvement of the pancreas in up to 6% of patients, clinically apparent pancreatitis due to sarcoid is rare.2,3 We describe a case of biopsy-proven pulmonary sarcoidosis associated with recurrent pancreatitis and improvement with corticosteroid treatment.

74. Sarcoidosis/Boeck Webpage
sarcoidosis / Boeck Website. www.xs4all.nl/~boeck . Dutch Website for the sarcoidosis / Boeck s disease from patients for patients and those interested.
http://www.xs4all.nl/~boeck/indexeng.html
Sarcoidosis / Boeck Website
Dutch Website for
the Sarcoidosis / Boeck's disease
from patients for patients and those interested.
There is also a Dutch language-version available ! Some information that you can find on these "Sarcoidosis/Boeck" pages:
With thanks to Maria Leffley for the help !
  • Ernst his Webpage with info about Sarcoidosis on the Net and in general.
  • Ernst his Webpage Sarcoidosis and children, a story from the Net.
  • Laurie her Webpage with aromatherapy in FAQ (frequently asked questions) form.
  • Some Dutch statistics How many visitors did we have ? See for yourself !
  • Several Sarcoidosis "fellow" Sites over the world.
  • People who like to have e-mail from you.
      Maybe you have an interesting page to publish here or remarks to tell us?
      E-mail: boeck@xs4all.nl
    "The Sarcoidosis / Boeck site is ment for Sarcoidosis patients and anybody with an interest in the disease Sarcoidosis.
    It doesn't cost anything just a little of your time and interest. This free website account is sponsored by Xs4all, an Internet provider throughout Holland.
  • 75. Inflammatory Myopathy
    Graftvs-host disease, 7 to 24 months post BMT. Granulomatous, Sarcoid; Immune; Infections. sarcoidosis, Myopathy; Neuropathy; Lung disease. sarcoidosis.
    http://www.neuro.wustl.edu/neuromuscular/antibody/infmyop.htm

    Front
    Search Index Links ... Patient Info
    Inflammatory and Immune Myopathies
    GENERAL FEATURES
    Antibodies
    CK: Serum

    Electrodiagnostic
    ...
    Calcinosis
    : X-rays
    Chondroitin sulfate C deficient

    Dermatomyositis

    Fasciitis

    Focal myositis
    ...
    Signal recognition particle
    Vasculitis: Small Large vessel SPECIFIC IMMUNE OR INFLAMMATORY MYOPATHIES Immune myopathies (Polymyositis) General aspects Classification Comparative features Collagen vascular disease Complement ... Quadriceps ; Other TRAPS Granulomatous Hemophagocytic lymphohistiocytosis Hereditary ... Multinodular polymyositis Necrotizing with Encephalopathy Paraneoplastic with Pipestem capillaries SRP antibodies ... MHC class I upregulation Skin lesions Erythema Gottron's papules Nailfold lesions From: Chinju, South Korea
    GENERAL FEATURES OF INFLAMMATORY MYOPATHIES
    Antibodies CK: Serum Electrodiagnostic Neoplasm associations ... Weakness Skin lesions

    76. Dermatlas: Online Dermatology Image Library Dermatology Image,sarcoidosis,granul
    Dermatlas Dermatology Images sarcoidosis,lupus pernio,granulomatous reaction,dermatology image images. Match ALL words Match ANY word. Dermatology Images,
    http://dermatlas.med.jhmi.edu/derm/result.cfm?Diagnosis=64

    77. Pulmonary Sarcoidosis - Respiratory Disorders Health Guide
    Definition, symptoms, susceptible populations, diagnosis, and treatment of pulmonary sarcoidosis. Respiratory Disease. Pulmonary sarcoidosis What is sarcoidosis?
    http://www.umm.edu/respiratory/sarcoid.htm

    Respiratory Diseases
    Lung Cancer Lung Diseases and Disorders... COPD... ... Site Index
    Related Resources Within UMM Clinical Immunology Family Medicine Pulmonary and Critical Care Medicine Respiratory Disease
    Pulmonary Sarcoidosis
    What is sarcoidosis?
    Sarcoidosis is a rare disease that results from inflammation. Ninety percent of the cases of sarcoidosis are found in the lungs, but it can occur in almost any organ. It causes small lumps, or granulomas, which generally heal and disappear on their own. However, for those granulomas that do not heal, the tissue can remain inflamed and become scarred, or fibrotic. Pulmonary sarcoidosis can develop into pulmonary fibrosis , which distorts the structure of the lungs and can interfere with breathing. Bronchiectasis , a lung disease in which pockets form in the air tubes of the lung and become sites for infection, can also occur What are the symptoms of sarcoidosis?
    Most sarcoidosis patients do not exhibit symptoms and probably are unaware they have the disease. Pulmonary sarcoidosis can cause loss of lung volume (the amount of air the lungs can hold) and abnormal lung stiffness. The following are the most common symptoms for sarcoidosis, however, each person may experience symptoms differently :

    78. Yale: Cardiothoracic Imaging - Sarcoidosis, Diffuse Interstitial Pattern
    The most common parenchymal pattern of sarcoidosis is a reticulonodular configuration, correlating with the noncaseating granulomas noted at pathology.
    http://info.med.yale.edu/intmed/cardio/imaging/cases/sarcoidosis/
    Sarcoidosis, diffuse interstitial pattern
    COMMENTS

    Twenty-eight year-old female with a history of minimal shortness of breath. The most common parenchymal pattern of sarcoidosis is a reticulonodular configuration, correlating with the non-caseating granulomas noted at pathology. Slightly less common is alveolar pattern made up of diffuse, small, indistinct opacities due to the alveolar filling with mononuclear cells. More...
    SHORTCUTS : See the Contents page for complete listing of all pages and topics.
    Anatomy Thoracic landmarks Lateral landmarks Heart radiographs Thoracic anatomy Cardiac anatomy Cardiac valves ANT view LAO view LAT view SA view Cross-sectional views Blood supply ANT coronaries LAO coronaries LAT coronaries RAO coronaries Bronchioles Breast anatomy Techniques Ionizing vs nonionizing Tomography vs projection Ionizing radiation Electromag. spectrum Tomography Radiography Radiographic density Rad. gray scales CT imaging Planar imaging Planar anatomy SPECT imaging SPECT anatomy ERNA Echocardiography Transesophageal Magnetic resonance Cases Aortic aneurysm Aortic regurgitation Atelectasis Carcinoma Carcinoma, ductal

    79. Sarcoidosis
    Up. sarcoidosis is a systemic granulomatous disease shich most commonly affects black, young adults. The most common ocular inflammation
    http://insight.med.utah.edu/opatharch/uvea/sarcoidosis.htm
    Home Up Contributors Submission Information ... Site Map Sarcoidosis is a systemic granulomatous disease shich most commonly affects black, young adults. The most common ocular inflammation seen in sarcoidosis is an anterior uveitis. This is a granulomatous type of uveitis which is characterized by large "mutton-fat" keratic precipitates on the cornea. In addition, there can be large nodule of the iris present, along with extensive posterior synechiae formation(#22246). Posterior inflammation may involve both the retina and the choroid with the classic picture of retinal peri-phlebitis forming "candle wax drippings." Histopathologically, sarcoidosis is characterized by a non-caseating, granulomatous inflammation with descrete foci of inflammation. These small foci of granulomatous inflammation on the surface of the iris may form koeppe nodules(#22247, #22249). In addition, the epithelioid cells in the granulomos may have small, eosinophilic, star-shaped inclusions called asteroid bodies or darker ovoid inclusions called Schaumann's bodies. Slit Lamp Photo #22246 Low Power #22247 High Power #22259 Home Up Conjunctiva Cornea ... Site Map John A. Moran Eye Center 50 North Medical Drive Salt Lake City UT 84132

    80. Sarcoidosis
    Background. sarcoidosis enters into any physicians differential diagnosis of a systemic illness with no obvious cause. The disease
    http://www.thedoctorsdoctor.com/diseases/sarcoidosis.htm
    Background Sarcoidosis enters into any physicians' differential diagnosis of a systemic illness with no obvious cause. The disease is more common in males and is ten times more frequent in American blacks. The disease may be discovered incidentally on routine chest radiographs as bilateral lung hilar lymphadenopathy. However, any organ can be involved and almost every clinical presentation has been documented depending upon the organs affected. The clinical course is unpredictable but 65-70% may recover with minimal residual changes. Permanent loss of lung function may occur in 20%. About 10% of patients die of cardiac, central nervous system disease, or progressive pulmonary fibrosis. Treatment is usually with steroids. The histologic hallmark of the disease is the non-caseating granuloma composed of an aggregate of epithelioid histiocytes with Langhans' type giant cells. Rarely necrosis is identified. The lung is the most common site of involvement but as mentioned, any organ may be involved. An abnormal immune response to a yet unidentified antigen is suspected as the cause. Patients have an increase in CD4+ Helper T lymphocytes and elevated levels of soluble IL-2 receptors. PCR studies have revealed mixed results over the possibility of a mycobacterial cause.

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