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         Primary Progressive Aphasia:     more detail
  1. Primary Progressive Aphasia
  2. False recognition of incidentally learned pictures and words in primary progressive aphasia [An article from: Neuropsychologia] by E. Rogalski, D. Blum, et all 2007-01
  3. Number words are special: Evidence from a case of primary progressive aphasia [An article from: Journal of Neurolinguistics] by F. Domahs, L. Bartha, et all
  4. Category and letter fluency in semantic dementia, primary progressive aphasia, and Alzheimer's disease [An article from: Brain and Language] by C.A. Marczinski, A. Kertesz, 2006-06-01

61. Neurologic Manifestations
primary progressive aphasia Frontal Dementia NorthWestern Univ (US). Primary ProgressiveAphasia Handbook - Feinberg School of Medicine/NorthWestern U (US).
http://www.mic.ki.se/Diseases/C10.597.html
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Diseases and Disorders Links pertaining to Neurologic Manifestations Alert! Patients and laypersons looking for guidance among the target sources of this collection of links are strongly advised to review the information retrieved with their professional health care provider. Start Page Contents: Agnosia Amnesia Aphasia Apraxias ... Vertigo
Cerebellar Ataxia Classification of Ataxias - Washington U./School of Med. (US) Hereditary Ataxia Overview - GeneTests The US National Ataxia Foundation - Minneapolis European Federation of Hereditary Ataxias Int'l Network of Ataxia Friends De ADCA-Vereniging Nederland [cerebellar atrophy/ataxia syndrome] - (NL) About Episodic Ataxia [Mark ? ]
Chorea Sydenham's Chorea (St. Vitus' Dance, Rheumatic Chorea) - Adam, via MedlinePlus The legend about Vitus - Catholic Online Saints
Tardive Dyskinesia (not on MeSH) About Tardive Dyskinesia [JR Brasic] - eMedicine Tardive Dyskinesia [B Alexander] - Virtual Hoispital
Dystonia Dystonia Dialogue , and about

62. Dementia
More likely to have change in level of consciousness. primary progressive aphasiaprogressive aphasia without true dementia. Jacob Creutzfeld Disease
http://neuroland.com/deg/dementia.htm
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Neuro disease
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Neuro Med
Overview of Dementia Diagnostic Criteria for Dementia Impaired social or occupational function Impaired memory, plus
one or more area of the following cognitive functions Abstract/problem solving Judgment Language Personality Clear consciousness Differentiate Depression from Dementia Depression Dementia Relatively rapid onset Depressive symptoms start before dementia Patient complains more than family Appears depressed Response of "I don't know" Inconsistent Cognitive impairment Response to antidepressant very slow onset depressive symptoms develop after cognitive decline Patient tends to deny any memory problem May or may not appear depressed Try to give an excuse or general answer Cognitive impairment fairly consistent Antidepressant may have no effect Causes of Dementia Alzheimer's dementia Multiinfarct dementia Normal Pressure Hydrocephalus 3 main symptoms: Dementia, Gait Apraxia, Incontinence Language functions preserved Most common cause of gait abnormality plus Dementia is multiinfarct dementia May progress over months to years then reach a plateau MRI shows large ventricles LP may result in temporary improvement Treatment is VP or LP shunt HIV dementia Younger patient Memory loss Frontal lobe dysfunction, personality change, social withdraw

63. Paper
primary progressive aphasia and the Role of the SpeechLanguage Pathologist.In deciding on a topic for my research paper I wanted
http://webpages.marshall.edu/~yarber1/paper.htm
Primary Progressive Aphasia and the Role of the Speech-Language Pathologist
In deciding on a topic for my research paper I wanted to pick something that I was personally interested in. I have a class where we discuss neurogenic disorders such as aphasia. This is a class I enjoy alot and I am very intrigued with the things we have learned about aphasia. As a focus for my research I chose to investigate a particular type of aphasia that I knew little about. While I have some knowledge about the disorder of aphasia, I have little understanding about a type of aphasia, called primary progressive aphasia (PPA). My specific interests were to learn how the disorders of aphasia and PPA differ, how they are alike, and what role the speech language pathologist might play when treating patients with PPA. Just as the amount of time for each stage may vary so can the effects of PPA on language. The patient may have naming difficulties, for example the patient may not be able to name something they use everyday like a toothbrush. They may substitute the wrong word, for example they may ask for a cup when they want a plate ("What is PPA?", 1996). Since the initial symptoms of PPA are similar to those of aphasia the patient could benefit from some of the same types of speech therapy (Cress,1999). I then decided to look at what role the SLP played in the rehabilitation of PPA. It was very hard to find any information specifically on therapy for PPA so I looked at what the role of the SLP is in the therapy of persion with aphasia in general. The rehabilitation of the person with aphasia involves several professions but the entire team looks to the SLP to learn the best ways of communication with the patient. They also provide the best means of communicating so the patient can express his/her basic needs. The SLP also helps the family of the patient deal with the disorder. The SLP will assist them in learning about the disorder and ways to communicated with the patient (Wallace, 1999).

64. References
Understanding primary progressive aphasia. (Date accessed, February 14, 2001). Woburn,MA. What is primary progressive aphasia? (Date accessed March 23,2001).
http://webpages.marshall.edu/~yarber1/references.htm
References Cress, King. (1996, Dec.) AAC Strategies for people with PPA without dementia: Two case studies.
Augmentative and Alternative Communication Journal. pp. 248-258. Elman, Roberta. (1999). Group Treatment of Neurogenic Communication Disorders. Butterworth-Heinemann, Woburn, MA. Journal of Speech and Hearing Research. pp.27-37 (From[Academic Search Elite]: EBSCO Publishing.) Retrieved April 1, 2001 from the World Wide Web: http://www.epnet.com/ehost/login.html. Understanding Primary Progressive Aphasia. (Date accessed, February 14, 2001). National Aphasia Association [Online]. Available http://www.aphasia.org/NAAppa.html. Wallace, Glorijean. (1999). Adult Aphasia Rehabilitation. Butterworth-Heinemann. Woburn, MA. What is Primary Progressive Aphasia? (Date accessed March 23,2001). Primary Progressive Aphasia Newsletter [Online]. Available http://dementia.ion.ucl.ac.uk/candid/factsheets/facts5.htm
Title Page
Research Paper

65. Prof. J.B. Orange
primary progressive aphasia The future of neurolinguistic and biologic characterization. Pragmaticsin frontal lobe dementia and primary progressive aphasia.
http://www.uwo.ca/fhs/csd/jborange_srp.html
Prof. J.B. Orange - Selected Recent Publications (last 3 years) Peer Reviewed
Brain and Language, 71
Brain and Language, 71
Neurology, 53,
Topics in Geriatric Rehabilitation, 14
Journal of Applied Communication Research, 26
Asha Division 2 Newsletter - Neurophysiology and Neurogenic Speech and Language Disorders, 8
Journal of Neurolingusitics, 11
Journal of Speech-Language Pathology and Audiology, 21
Books, Monographs, and Chapters
Orange, J.B. (in press). Family caregivers, communication and Alzheimer's disease. In M.L. Hummert and J. Nussbaum (Eds.) Aging, communication, and health: Multidisciplinary perspectives. Mahwah, NJ: Lawrence Erlbaum Associates. Neurogenic communication disorders: a functional approach (pp. 220-246). NY: Thieme. Clinics in Geriatric Medicine: Communication between older adults and their physicians. (pp. 153-173). Philadelphia, PA: W.B. Saunders. Stroke rehabilitation - Physical medicine and rehabilitation: State of the art reviews. Volume 12 (3) Pragmatics in neurogenic communication disorders (pp. 153-177). Oxford, UK: Pergamon Press.

66. Edu1.com , Education First
primary progressive aphasia and Related Disorders A newsletter providing informationon primary progressive aphasia and related disorders, its introduction
http://www.edu1.com/edu1/directory/cat.asp?id=167&u=A

67. CUADERNOS DE NEUROLOGIA
Translate this page 11. Mesuam M. primary progressive aphasia. Ann Neurol 22 (4) 533-534, 1987. 12. 14.WeintraubS. primary progressive aphasia. Arch Neurol 47 1329-1335, 1990.
http://escuela.med.puc.cl/publ/Cuadernos/1994/pub_11_94.html

68. JW Neurology -- Sign In
Summary and Comment. primary progressive aphasia A Review. primary progressive aphasia.Ann Neurol 2001 Apr; 49425432.Medline abstractDownload citation.
http://neurology.jwatch.org/cgi/content/full/2001/823/3

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69. Ap : On Medical Dictionary Online
Aphasia, Post Ictal Aphasia, Post Traumatic Aphasia, PostIctal Aphasia, Post-TraumaticAphasia, Posterior Aphasia, primary progressive aphasia, Progressive
http://www.online-medical-dictionary.org/?q=~Ap

70. Aphasia Hope Foundation
neurologist. You are right, primary progressive aphasia (PPA) does nottypically start with a stroke or a sudden onset. Instead, the
http://www.aphasiahope.org/forums/viewThread.jsp?forum=1&thread=410

71. Personal Profile
Neurology, 56, 944950. Croot, K. (2000) primary progressive aphasia A tutorial.Acquiring Knowledge in Speech, Language and Hearing, 2, 90-92.
http://www.maccs.mq.edu.au/people/profile.htm?ID=92600905

72. Phase III
can often be masked and difficult to diagnose.” http//www.zmag.org/content/showarticle.cfm?SectionID=51 ItemID=2928“What is primary progressive aphasia?
http://news.phaseiii.org/postp1014.html
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The Bush Family View previous topic ... View next topic Author Message NOLAJBS
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Joined: Nov 13, 2003
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Location: New Orleans, LA
Posted: Tue Apr 27, 2004 1:34 am Post subject: Bush's Brain Damage: Aphasia? Now, here's something interesting to go along with Story ID# 2753 . But this picture will help set the stage: http://www.virtualexp.net/dope/cocexp4.html
TyrannyResponseUnit@c0bal tdot com Forums wrote: George Bush and Aphasia
a•pha•sia (uh-fay'-zhuh) n. An impairment of the ability to use or comprehend words, usually acquired as a result of a stroke or other brain injury. http://www.aphasia.org/
Aphasia: A Spouse’s Perspective: [Laura Bush’s?] http://www.aphasia.org/NAAspouseperspective.html “The first priority was to simplify. My husband needed rest and plenty of it There was not time for the busy lifestyle we had maintained before the stroke..…” “George W. Bush seems to have taken this to the extreme early in his tenure as president. A humorous, fake resume for Bush suggests that he set the record for most days on vacation by any president in U.S. history…. While we couldn't find the exact tally for Clinton's last year in office, it's reasonable to expect he didn't increase his vacation rate. And in barely three years in office, George W. Bush has already taken more vacation than Clinton did in seven years.” http://ask.yahoo.com/ask/20031001.html

73. The UCLA Focal-Type Dementias Clinic
disturbances. Some of these disorders are part of the spectrum of FTD,such as primary progressive aphasia and semantic dementia. Others
http://neurology.medsch.ucla.edu/dementia.htm

74. SIU School Of Medicine, Office Of Continuing Medical Education
ABETA-1-42-AMYLOID, TAU- AND S-100-PROTEIN IN CSF, NEUROLITE-SPET AND MRI IN THREEPATIENTS WITH primary progressive aphasia L. Maeck, G. Stiens, J. Meller*, M
http://www.siumed.edu/cme/55c.html
Download Alzheimer's Abstracts Here
A-BETA-1-42-AMYLOID, TAU- AND S-100-PROTEIN IN CSF, NEUROLITE-SPET AND MRI IN THREE PATIENTS WITH PRIMARY PROGRESSIVE APHASIA
L. Maeck, G. Stiens, J. Meller*, M. Otto # J. Wiltfang, G. Stoppe
Departments of Psychiatry, Neurology # and Nuclear Medicine* Georg-August-University, (37075) Goettingen, Germany
Objectives: Primary Progressive Aphasia (PPA) is a rare disorder, which has been shown to progress either to frontotemporal degeneration (FTD) or to Alzheimer's disease (AD) in the majority of cases. In order to achieve early classification with differential therapeutic impact (e.g. AchE-Inhibitors or not), inves-tigation of CSF-proteins together with neuroimaging might be useful. There are no previous reports on this topic.
Methods: Three patients (case 1: F, 71y, case 2: M, 51y, case 3: M, 45y) presented with typical symptoms of PPA, in cases 2 and 3 of non-fluent-type, confirmed by extended neuropsychological examinations.
Neurological, psychiatric and clinical workup revealed no other pathology except for fasciculations, which developed after more than 3 years of pure PPA-symptoms. Family history was negative. APOE-Genotype

75. Wauu.DE: Health: Conditions And Diseases: Neurological Disorders: Dementia: Prim
Wauu.DE Health Conditions and Diseases NeurologicalDisorders Dementia primary progressive aphasia.
http://www.wauu.de/Health/Conditions_and_Diseases/Neurological_Disorders/Dementi
Home Health Conditions and Diseases Neurological Disorders ... Dementia : Primary Progressive Aphasia Search DMOZ-Verzeichnis:
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76. Health Search Engine - Primary Progressive Aphasia Category
All Sub Categories in primary progressive aphasia No Sub category found.All Sites in primary progressive aphasia . Understanding
http://www.cheap-hotels-amsterdam.com/Senior_Health_Health/Primary_Progressive_A
Primary Progressive Aphasia / Dementia Senior Health Home Search The Site
Our Partners Pet Food FDA rLyrics Computer Search Engine ... Lyrics Search Engine All Sub Categories in 'Primary Progressive Aphasia' No Sub category found All Sites in 'Primary Progressive Aphasia' Understanding Primary Progressive Aphasia - An article with a description, assistance available and where to obtain additional information. WebMD Live Chat Transcript: - Living with aphasia with Martha Taylor Sarno, MD.
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77. NodeWorks - Dementia: Primary Progressive Aphasia
thumbnail, 1. Understanding primary progressive aphasia An article with adescription, assistance available and where to obtain additional information.
http://dir.nodeworks.com/Health/Conditions_and_Diseases/Neurological_Disorders/D
in entire NodeWorks Directory in Health in Neurological Disorders in Dementia in ++ Primary Progressive Aphasia Top Health Neurological Disorders Dementia Primary Progressive Aphasia A progressive form of dementia characterized by the global loss of language abilities and initial preservation of other cognitive functions. Understanding Primary Progressive Aphasia An article with a description, assistance available and where to obtain additional information. WebMD Live Chat Transcript: Living with aphasia with Martha Taylor Sarno, MD.
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78. Header
primary progressive aphasia (PPA) affords the opportunity to define these correlates,since its pathology does not break down the coupling of regional cerebral
http://pet.radiology.uiowa.edu/webpage/Research/research projects/Activation.htm
A P.E.T. Activation Study of Progressive Aphasia: Developing New Standards for Imaging Defective Cognition and Understanding Cerebral Disease
Thomas Grabowski, MD We propose to employ modified versions of two language tasks which we have investigated in young normal subjects: verb generation and picture naming. Progressive aphasics will be studied longitudinally, with three MRI and three P.E.T. scans at one-year intervals. Elderly normal controls will be studied in a single session using the same tasks and also under experimental conditions designed to induce errors in task performance. Image analysis will be performed in the Human Neuroanatomy and Neuroimaging Laboratory using local software (PET-BRAINVOX) which supports both anatomically- based and standard pixel-based analyses. Back Topics Overview Patient Info Facilities Personnel ... Home

79. NRU's Publication Database
aphasia without clinical signs of intellectual or behavioral impairment, satisfyingMesulam s clinical criteria of primary progressive aphasia, as 4 yrs of
http://nru.dk/cgi-bin/extract?deleclusef1990a

80. Hodges & Patterson
Brain. Review pc (1995) primary progressive aphasia and semantic dementia.Neurocase, 1, 3954. Sinnatamby R, Antoun NA, Freer CEL
http://www.iias.or.jp/research/res_gengo/gengo98rpt/Hodges.html
IIAS Lecture Japan November 1998 "Semantic Dementia and the Progressive Aphasic Syndromes: Clinical and Neuroradiological Features" John R Hodges and Karalyn Patterson
MRC Cognition and Brain Sciences Unit, Cambridge, UK
Pick's disease, Progressive Aphasia and Semantic dementia
Although the term semantic dementia is recent, the syndrome has been recognised for many years. In 1892 Arnold Pick reported a patient with amnestic aphasia and left temporal lobe atrophy. Many other such patients were reported in the PickÕs disease literature of the early 20th century. Patients with "loss of word meaning" were also reported from Japan under the heading of "Gogi aphasia". In 1975 Warrington reported what she termed Òselective impairment of semantic memoryÓ and proposed that the combination of transcortical aphasia and associative agnosia observed in three patients with cortical atrophy reflected a fundamental loss of semantic memory about the items which thereby affected naming, word comprehension, and object recognition. Semantic memory is the term applied to the component of long-term memory which contains the permanent representation of our knowledge about things in the world and their inter-relationship, facts and concepts as well as words and their meaning. Mesulam's 1982 paper rekindled neurological interest in the focal dementias when he reported clinical syndrome of "slowly progressive aphasia without generalised dementia" in six patients with a 5 to 10 year history of insidiously worsening aphasia in the absence of signs of more generalised cognitive failure. Since 1982 there have now been over 40 papers reporting some 100 patients who fulfil the criteria for progressive aphasia. Although the language deficits seen in such patients are heterogeneous, two broad groups can be identified: progressive fluent aphasia with features corresponding to those reported above (which we prefer to call semantic dementia) and progressive non-fluent aphasia in which there is selective breakdown in the phonological and syntactic aspects of language. The latter syndrome will not be discussed further here

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