61. Ovarian Failure (premature) - General Practice Notebook ovarian failure (premature). In one series, it accounted for 36% of cases of primary amenorrhoea, and 29% of cases of secondary amenorrhoea. http://www.gpnotebook.co.uk/cache/-315293685.htm

ovarian failure (premature) This is defined as menopause occurring in women prior to the age of 40 years. It is a not uncommon cause of amenorrhoea. In one series, it accounted for 36% of cases of primary amenorrhoea, and 29% of cases of secondary amenorrhoea. Diagnosis requires elevated gonadotrophins - FSH above 40 IU per litre together with raised LH and low oestradiol (less than 100 pmol per litre) on at least two occasions. Ultrasound usually reveals small ovaries, a small uterus and a thin endometrium. Note that reference ranges may vary between laboratories. Click here for more information...

62. WHAT CAUSES AMENORRHEA? Anorexia and Bulimia. The eating disorders anorexia and bulimia may be a primary factor in many cases of FHA. Premature ovarian failure. http://www.ucdmc.ucdavis.edu/ucdhs/health/a-z/101Amenorrhea/doc101causes.html

WHAT CAUSES AMENORRHEA? Delayed Puberty The most common cause of primary amenorrhea is delayed puberty due to some genetic factor that delays physical development. Being short is the most common sign of this, although sometimes a family history of delayed menstruation can indicate this situation. Time usually resolves the problem. Functional Hypothalamic Amenorrhea (FHA) and Eating Disorders Functional hypothalamic amenorrhea (FHA) is the absence of menstruation due to disturbances in the thyroid gland and hypothalamus-pituitary-adrenal (HPA) system. FHA may be due to different factors, most unknown. The hypothalamus and the pituitary gland regulate the reproductive hormones. It triggers the production and release of steroid hormones ( glucocorticoids ), including the primary stress hormone cortisol . The HPA system manages appetite and mood as well. Anorexia and Bulimia. The eating disorders anorexia and bulimia may be a primary factor in many cases of FHA. Both weight loss and changes of appetite may cause hormonal abnormalities. Such changes may be due to a primitive protective biologic mechanism, which was designed to prevent potentially harmful pregnancies during times of famine. Hormonal changes to extreme weight loss and reduced fat stores include low thyroid levels (hypothyroidism) and excessive stress hormone levels (hypercortisolism), which in turn reduce reproductive hormones. Reducing stress hormones, in one study, helped elevate reproductive hormones in women with FHA.

63. The Latest Facts About Premature Ovarian Failure, By Michael Heard, MD - DrDonni fertilization enables POF women the opportunity to reproduce after ovarian failure with high Finally, it is of primary importance that a woman diagnosed with http://www.drdonnica.com/guests/00006208.htm

We subscribe to the HONcode principles. Verify here Michael J. Heard, M.D. Dr. Heard is a Reproductive Endocrinologist in private practice in Houston, Texas. Board certified in Obstetrics and Gynecology and a Fellow in the American College of Obstetricians and Gynecologists, Dr. Heard maintains a specialized focus on the evaluation and treatment of premature ovarian failure (POF). He is the medical director of the Houston POF Support Group, one of the largest POF support groups in the country.  He also interacts with patients with POF all over the United States and around the world through his private practice and the internet. Dr. Heard is a member of the Houston chapter of RESOLVE, the National Fertility Association, and the American Society of Reproductive Medicine. Dr. Heard received his M.D. from Emory University School of Medicine in Atlanta, Georgia. He trained in obstetrics and gynecology at the University of Tennessee in Memphis and went on to serve  four years on active duty as an officer in the United States Air Force.  Dr. Heard completed a three-year Fellowship in Reproductive Endocrinology and Infertility at Baylor College of Medicine in Houston. He was recently appointed Assistant Clinical Professor at the University of Texas Health Science Center in Houston. The Latest Facts About Premature Ovarian Failure

64. Entrez PubMed Based on its primary structure, it appears to be novel and has no motifs that OP1 as an antigen may play a role in murine autoimmune premature ovarian failure. http://www.biomedcentral.com/pubmed/10433232

Entrez PubMed Nucleotide Protein ... Books Search PubMed Protein Nucleotide Structure Genome Books CancerChromosomes 3D Domains Domains Gene GEO GEO DataSets HomoloGene Journals MeSH NCBI Web Site OMIM PMC PopSet SNP Taxonomy UniGene UniSTS for Limits Preview/Index History Clipboard ... Text Version Entrez PubMed Overview FAQ Tutorial New/Noteworthy ... E-Utilities PubMed Services Journals Database MeSH Database Single Citation Matcher Batch Citation Matcher ... Cubby Related Resources Order Documents NLM Gateway TOXNET Consumer Health ... PubMed Central Summary Brief Abstract Citation ASN.1 MEDLINE XML UI List LinkOut Related Articles Cited in Books CancerChrom Links Domain Links 3D Domain Links GEO DataSet Links Gene Links Genome Links GEO Links HomoloGene Links Nucleotide Links OMIM Links PMC Links Cited in PMC PopSet Links Protein Links SNP Links Structure Links UniSTS Links Show: Sort Author Journal Pub Date Text File Clipboard E-mail Order Endocrinology. 1999 Aug;140(8):3720-6. Related Articles, Links Comment in: Endocrinology. 1999 Aug;140(8):3401-3. A mouse gene encoding an oocyte antigen associated with autoimmune premature ovarian failure. Tong ZB, Nelson LM.

65. UK Chandler Medical Center - Primary Template Premature ovarian failure. Under Construction! . • OBGYN Home Page •. http://www.mc.uky.edu/obg/Curr/Unit4_RE/Menopause/POF.htm

Premature Ovarian Failure Under Construction! OB-GYN Home Page

66. Ovarian Dysgenesis With Balanced Autosomal Translocation. Tullu MS, Arora P, Par and unbalanced X6 translocations, respectively implications for the investigation of ovarian failure. X, t(X;15) (q21;q23) associated with primary amenorrhea http://www.jpgmonline.com/article.asp?issn=0022-3859;year=2001;volume=47;issue=2

67. Amenorrhea The causes of primary amenorrhea are also quite different from secondary and decreased libido along with her amenorrhea may have premature ovarian failure. http://www.advancedfertility.com/amenor.htm

IVF Pregnancy Rates IVF Pricing Options In Vitro Fertilization Egg Donation ... Become a Patient Secondary Amenorrhea Lack of menstrual periods in a woman that has had periods previously Background Secondary amenorrhea is the absence of menstrual periods for 6 months in a woman who had previously been regular, or for 12 months in a woman who had irregular periods. This problem is seen in about 1% of women of reproductive age. Primary amenorrhea is when the woman has never had a period in her life. This page will not discuss primary amenorrhea which is rare. The causes of primary amenorrhea are also quite different from secondary amenorrhea. The most common cause of secondary amenorrhea in reproductive age women is pregnancy and this should always be excluded by physical exam and laboratory testing for the pregnancy hormone - HCG. History A good history can reveal the etiologic diagnosis in up to 85% of cases of amenorrhea. A detailed menstrual history should be taken. Any history of galactorrhea (milky discharge from the breasts) is important and indicates the need for a prolactin hormone level to rule out hyperprolactinemia. A woman who has had hot flashes, breast atrophy and decreased libido along with her amenorrhea may have premature ovarian failure.

68. D FÜHRER: Identification Of FOXL2 (European Journal Of Endocrinology) failure is characterized by absence or reduction in the number of germcells, resulting in either primary amenorrhea or premature ovarian failure (POF), ie http://www.eje.org/eje/146/eje1460015.htm

HIGHLIGHT: Lessons from studies of complex genetic disorders: identification of FOXL2-a novel transcription factor on the wing to fertility Dagmar Führer III. Department of Medicine, University of Leipzig, Leipzig, Germany Introduction Download the FULL TEXT of this article in Acrobat PDF format. If you have not previously downloaded PDF files we suggest you access our Advice page for further information. European Journal of Endocrinology Return to the Contents List - Vol. 146 Part 1 or The List of Reviews and Highlights

69. Blackwell Synergy - Cookie Absent The incidence of premature ovarian failure (POF) in women with epilepsy has not been had POF compared with two of nine women with primary generalized epilepsy http://www.blackwell-synergy.com/links/doi/10.1046/j.1528-1157.2001.13701r.x/abs

Home An Error Occurred Setting Your User Cookie A cookie is a small amount of information that a web site copies onto your hard drive. Synergy uses cookies to improve performance by remembering that you are logged in when you go from page to page. If the cookie cannot be set correctly, then Synergy cannot determine whether you are logged in and a new session will be created for each page you visit. This slows the system down. Therefore, you must accept the Synergy cookie to use the system. What Gets Stored in a Cookie? Synergy only stores a session ID in the cookie, no other information is captured. In general, only the information that you provide, or the choices you make while visiting a web site, can be stored in a cookie. For example, the site cannot determine your email name unless you choose to type it. Allowing a web site to create a cookie does not give that or any other site access to the rest of your computer, and only the site that created the cookie can read it. Please read our for more information about data collected on this site.

70. Cancer.gov women undergoing adjuvant or neoadjuvant chemotherapy for primary breast cancer. history, and chemotherapy regimen with ovarian failure (permanent cessation of http://www.cancer.gov/clinicaltrials/view_clinicaltrials.aspx?version=healthprof

71. Türk Fertilite Dergisi Results Premature ovarian failure is a syndrome characterized by hypoestrogenism, hypergonadism (FSH 40IU/L), primary or secondary amenorrhea in women below http://www.tivak.org.tr/journal/goster.php?id=84

72. ASSOCIATION OF ANTIZONA PELLUCIDA ANTIBODIES IN HUMAN PREMATURE OVARIAN FAILURE known about the causes of Premature ovarian failure (POF) in defined as the loss of ovarian function before Such a primary relationship might follow an initial http://www.abington-repromed.com/researchpof.html

ASSOCIATION OF ANTIZONA PELLUCIDA ANTIBODIES IN HUMAN PREMATURE OVARIAN FAILURE AND INFERTILITY Research Objective We propose that the presence of anti-zona pellucida antibodies can be detected in human serum. By screening serum obtained from donors with a) POF, b) subfertility, and c) neither of those conditions we intend to determine if their is a correlation between the presence of aZPA and POF in women. Introduction: Little is known about the causes of Premature Ovarian Failure (POF) in women. This disorder is defined as the loss of ovarian function before the age of forty. It is clinically characterized by secondary amenorrhea and endocrinologically by a hypergonadotropic, hypoestrogenic state. Unfortunately, a definite etiological factor can not be determined for most cases (van Kasteren, 1999). Currently, the condition is divided into two classes: excessive depletion of follicles and follicles that are present but fail to function properly. It is also likely that different classes POF exist due to different causes or varying levels of the agents responsible for this disorder. It is possible that one of the major or contributing causes of POF dysfunction involves the autoimmune reaction against the oocyte and/or other components of the follicle. Such a primary relationship might follow an initial abnormal exposure of zona material to the immune system. Alternatively, in POF or other types of pathology, anti zona pellucida antibodies (aZP) might form as a secondary consequence of disease conditions (Shivers and Dunbar, 1977).

73. PharmGKB: Ovarian Failure, Premature Ovary Syndromes, Resistant; Premature ovarian failure; Premature ovarian failures; Resistant Ovary Syndrome; Resistant Ovary Syndromes. PharmGKB primary Data. http://www.pharmgkb.org/do/serve?objId=PA446361&objCls=Disease

74. Clinical Guidelines 75, Epithelial ovarian cancer, QRG 75 (174K). Guideline 75 40, Lipids and the primary prevention of coronary 35, Diagnosis and treatment of heart failure due to http://www.sign.ac.uk/guidelines/published/

Clinical Guidelines Items marked are available in Acrobat format ( info This list has been categorised by guideline subject. You can also view a list by guideline number Cancer CHD and Stroke Child Health ... Other Cancer No. Guideline Title Quick reference guide Full guideline Publication Date Long term follow up care of survivors of childhood cancer January 2004 Epithelial ovarian cancer October 2003 Cutaneous melanoma July 2003 Management of colorectal cancer [Dataset information] March 2003 Control of pain in patients with cancer June 2000 Breast cancer in women October 1998 Management of adult testicular germ cell tumours September 1998 Management of lung cancer February 1998 CHD and Stroke No. Guideline Title Quick reference guide Full guideline Publication Date Management of patients with stroke: Rehabilitation, prevention and management of complications, and discharge planning

75. Ivf-infertility.com | Polycystic Ovarian Syndrome (PCOS) Polycystic ovarian syndrome (PCOS), is a primary ovarian condition and is characterized by the risk of destruction of the ovaries leading to ovarian failure. http://www.ivf-infertility.com/infertility/pcos.php

Community Message Board Chat Forum Infertility Introduction Causes Of Infertility Age And Infertility PCOS ... Sex Selection IVF and ICSI Introduction IVF Procedure Risks of IVF Outcome of IVF ... ICSI GIFT and ZIFT GIFT and ZIFT Tubal Embryo Transfer Donation Introduction Sperm Donation Egg Donation Embryo Donation Insemination Introduction Vaginal Insemination Cervical Insemination Intrauterine Insemination ... Intratubal Insemination Surrogacy Introduction Guidelines And Protocols Adoption Introduction Adopting In The UK Children With Disabilities Overseas Adoption Resources FAQs Glossary Links And Contacts Bookstore ... Advertising PCOS Polycystic Ovarian Syndrome Incidence of Polycystic Ovarian Syndrome Polycystic ovarian syndrome (PCOS) accounts for 90% of women with oligomenorrhoea (infrequent periods) and 30% of women with amenorrhoea (absent of periods) and over 70% of women with anovulation. Diagnosis of Polycystic Ovarian Syndrome Laparoscopy Laparoscopy allows direct inspection of the ovaries; the ovaries are enlarged and polycystic. However, polycystic ovaries may appear normal at laparoscopy.

76. Colorado HealthSite ~ Rapid Bone Loss In Breast Cancer Patients Who Receive Adju treatment that is given as an addon to the primary cancer treatment of the most common side effects of adjuvant chemotherapy is ovarian failure or premature http://www.coloradohealthsite.org/CHNReports/chemo_boneloss.html

Rapid Bone Loss in Breast Cancer Patients Who Receive Adjuvant Chemotherapy Ovarian Failure After Adjuvant Chemotherapy Is Associated with Rapid Bone Loss in Women With Early-Stage Breast Cancer, by Charles L. Shapiro, Judith Manola, and Meryl Leboff; Journal of Clinical Oncology, July 15, 2001. Background Here is the important background information that the authors give us: over the past 30 years, mammographic screening and early detection of nonpalpable breast cancers has increased the number of breast cancer survivors, guidelines from that National Institutes of Health and the National Comprehensive Cancer Network recommend adjuvant chemotherapy (Ed: adjuvant chemotherapy = chemotherapy treatment that is given as an add-on to the primary cancer treatment) for all invasive breast cancer tumors greater than 1 cm, one of the most common side effects of adjuvant chemotherapy is ovarian failure or premature menopause. This premature menopause occurs in 63% to 85% of women treated with cyclophosphamide, methotrexate, and fluorouracil and 50% of women treated with anthracycline, patients over 40, who are closer to their natural menopausal age, develop ovarian failure after a shorter duration of chemotherapy, typically within the first few months

77. COCHRANE MENSTRUAL DISORDERS AND SUBFERTILITY GROUP Nonsteroidal antiinflammatory drugs for primary dysmenorrhoea (Cochrane Review); induction in women with spontaneous premature ovarian failure (Cochrane Review http://www.mediscope.ch/cochrane-abstracts/g180index.htm

COCHRANE MENSTRUAL DISORDERS AND SUBFERTILITY GROUP Abstracts of Cochrane Reviews The Cochrane Library Issue 4, 2001 The full text of these reviews and protocols is available in [The Cochrane Library] indicates the review is new in the current release of the Library. indicates the review has been substantially amended since the last issue of the Library. Note: 'Protocols' are the introduction, objectives, materials and methods for reviews currently being prepared. Reviews Androgens versus placebo or no treatment for idiopathic oligo/asthenospermia (Cochrane Review) Antifibrinolytics for heavy menstrual bleeding (Cochrane Review) Barrier agents for preventing adhesions after surgery for subfertility (Cochrane Review) Bromocriptine for idiopathic oligo/asthenospermia (Cochrane Review) ... Oral oestrogen replacement therapy versus placebo for hot flushes (Cochrane Review) Ovulation induction with urinary follicle stimulating hormone versus human menopausal gonadotropin for clomiphene-resistant polycystic ovary syndrome (This review has been withdrawn by the editorial group. Abstract not available)

78. Unusual Presentation Of Primary Ovarian Pregnancy ABSTRACT primary ovarian pregnancy is a rare entity, the reported incidence Pregnancy; ovarian failure, Premature/DI; Uterus; Laparotomy; Human; Female; Adult http://medind.nic.in/imvw/imvw3128.html

79. Menopause climacteric arthritis; ovarian failure; perimenopause; premenopausal menorrhagia. guidance is given on how to obtain freeof-charge primary research results via http://www.icongrouponline.com/health/Menopause_Ph.html

ICON Health Publications Official Health Sourcebooks MENOPAUSE A Bibliography, Medical Dictionary, and Annotated Research Guide to Internet References (climacteric arthritis; ovarian failure; perimenopause; premenopausal menorrhagia) P A P E R B A C K Paperback Book Paperback Book Order by phone: 800-843-2665 (within USA) 1-201-272-3651 (from outside USA) Paperback Book Shipped in 3 to 5 business days E B O O K Electronic File * E-Book version sent via e-mail in 2 business days Electronic File *E-Book version sent via e-mail in 2 business days Pages Price $78.95(USD) ISBN Published Synopsis In March 2001, the National Institutes of Health issued the following warning: "The number of Web sites offering health-related resources grows every day. Many sites provide valuable information, while others may have information that is unreliable or misleading." Furthermore, because of the rapid increase in Internet-based information, many hours can be wasted searching, selecting, and printing. Since only the smallest fraction of information dealing with menopause is indexed in search engines, such as www.google.com or others, a non-systematic approach to Internet research can be not only time consuming, but also incomplete. This book was created for medical professionals, students, and members of the general public who want to conduct medical research using the most advanced tools available and spending the least amount of time doing so. Related Conditions/Synonyms climacteric arthritis; ovarian failure; perimenopause; premenopausal menorrhagia

80. POF Support Group: Research: Identification Of Genes Associated With Primary Gon Premature ovarian failure Support Group. Home . Identification of genes associated with primary Gonadal failure Massachusetts General Hospital. http://www.pofsupport.org/research/gonadal.htm

About the POFSG Contact Us Our Mission Our History ... Home Identification of genes associated with Primary Gonadal Failure - Massachusetts General Hospital Cara Penney, a Physician Assistant who works with Dr. Ann Taylor on POF research studies. Currently, they are involved in recruiting for the following two POF studies: They are also asking POF women to provide a small amount of blood in the hopes of better understanding the possible autoimmune involvement in the development of POF. Currently, this blood sample needs to be drawn at Massachusetts General Hospital. A medical history will be obained.This study is funded by the NIH and may have therapeutic implications in the next 5 years. Please call Cara Penney, PA-C at (617) 726-9263 if you are interested or have any questions. Dr. Ann Taylor is a practicing Reproductive Endocrinologist at Massachusetts General Hospital. She is accepting new patients for consultation and appointments can be made at (617) 726-8433.

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