41. Orthostatic Intolerance Intolerance Syndromes Hyperadrenergic orthostatic hypotension Orthostatic tachycardia syndrome postural orthostatic tachycardia syndrome Postural tachycardia http://www.biotech.vt.edu/ncs_homepage/OrthoIntol.html

Orthostatic Intolerance David Robertson, MD Vanderbilt University Nashville Tennessee Orthostatic intolerance is present when patients experience symptoms such as lightheadedness, palpitations, tremulousness, and poor concentration during standing. Many patients also note other symptoms with upright posture: visual changes, discomfort in the head or neck, throbbing of the head, poor concentration, tiredness, weakness and occasionally fainting. For many years, such patients were felt to have deconditioning and were encouraged to pursue a more vigorous exercise regimen. However, recently it has become clear that many individuals with these symptoms have a more serious problem than mere deconditioning. Indeed, a number of cardiovascular and autonomic abnormalities have recently been detected. These include, in some patients, a reduced blood volume, excessive loss of plasma from the blood vessels on standing, excessive salt loss through the kidney, and abnormalities in the function of the autonomic (involuntary) nervous system. However, not every patient has all these abnormalities. Heterogeneity.

42. CFIDS JAMA 1995 September 27; 274(12) 961967. postural orthostatic tachycardia syndrome. Stewart JM Transient orthostatic hypotension is common in adolescents. http://www.cfids.org/youth/articles/medical/nmh.asp

What is CFIDS? What is CFIDS in Youth? Other Resources NMH and OI* in Children and Adolescents Medical Journal Articles * NMH=Neurally Mediated Hypotension, OI=Orthostatic Intolerance Following is a list of articles about neurally mediated hypotension and orthostatic intolerance in youth that have been published in the peer-reviewed medical literature. If we have been able to locate the article's abstract on line, we have provided a link to that abstract. If you wish to read an article that does not have a link, please contact your local medical library or hospital. Most of these articles focus on children and adolescents. To read articles about research in adults, do a search on PubMed , the search engine of the National Library of Medicine. Review Articles and Introductory Materials Neurally Mediated Hypotension Postural Orthostatic Tachycardia Syndrome Cerebral Blood Flow and Syncope ... Ehlers-Danlos Syndrome Review Articles and Introductory Materials General Information Brochure on Neurally Mediated Hypotension and its Treatment Neurally Mediated Hypotension Working Group, Johns Hopkins Hospital Grubb BP: Cerebral syncope: New insights into an emerging entity J Peds 2000 April;136(4):431-432.

43. CFIDS of OI There are many types of OI, but two forms have been linked with CFIDS in research studies NMH and postural orthostatic tachycardia syndrome (POTS). http://www.cfids.org/about-cfids/orthostatic-intolerance.asp

Symptoms Diagnosis Related Conditions Do I Have CFIDS? ... Profiles Diagnosis: Orthostatic Intolerance (OI) Orthostatic intolerance (OI) is the development of symptoms while standing or sitting upright. It has been associated with chronic fatigue and immune dysfunction syndrome (CFIDS) in both adults and children. The connection between OI and CFIDS was first introduced in 1995, by Rowe and associates at Johns Hopkins University, who identified neurally mediated hypotension (NMH) in CFIDS patients. Since 1995, scientists have learned much more about the broader problem of OI in CFIDS, of which NMH is just one form. It is now thought that many CFIDS patients (up to 97% in some studies) have some form of OI and it seems to be a particular problem in youth with CFIDS. Types of OI There are many types of OI, but two forms have been linked with CFIDS in research studies: NMH and postural orthostatic tachycardia syndrome (POTS). NMH is a precipitous drop (at least 20-25 mm Hg) in systolic blood pressure when standing. The blood pressure drop is accompanied or preceded by an increase in symptoms. POTS is a rapid increase in heart rate (pulse) of more than 30 beats per minute (bpm) from baseline, or to more than 120 bpm total, during the first 10 minutes of standing.

44. Pots: An Overview POTS Place A Guide to postural orthostatic tachycardia syndrome. POTS An overview. postural orthostatic tachycardia syndrome (POTS) is one of these disorders. http://potsplace.com/pots_an_overview.htm

DINET Home What's New? Physician List Newsletter ... Search POTS Place POTS Overview Symptoms Mechanisms Causes ... Links NCS About NCS Links PAF Links MSA Links Support Meet Others Support Groups Forum Resources Newsletters Assistance Help Us Donate Volunteer Advise Dysautonomia Information Network POTS Place: A Guide to Postural Orthostatic Tachycardia Syndrome POTS: An overview Help Us Standing up is something most of us take for granted; we've been doing it since childhood. Our bodies automatically adjust to the pull of gravity by increasing vascular tone, heart rate and cardiac output. Blood vessels contract, heart rates increase and our systolic blood pressure remains the same or decreases slightly while diastolic pressure However, the simple act of standing up can be a challenge for some people. There are disorders that affect the bodies ability to appropriately adjust to the pull of gravity. These disorders are referred to as orthostatic intolerance. Postural orthostatic tachycardia syndrome (POTS) is one of these disorders. Postural orthostatic tachycardia syndrome is defined by excessive heart rate increments upon upright posture. A person with POTS will experience heart rates that increase 30 beats or more per minute upon standing and/or increase to 120 beats or more per minute upon standing (Grubb, 2000). These exaggerated heart rate increases usually occur within 10 minutes of rising.

45. Vanderbilt University Autonomic Dysfunction Center - Orthostatic Intolerance Orthostatic tachycardia syndrome, Sympathicotonic orthostatic hypotension. postural orthostatic tachycardia syndrome (POTS), Mitral valve prolapse syndrome. http://www.mc.vanderbilt.edu/gcrc/adc/oi.html

Overview History Faculty Research ... Patient Information Orthostatic Intolerance What is Orthostatic Intolerance? When orthostatic symptoms occur in patients, but blood pressure does not fall as much as 20/10 mmHg on assumption of upright posture, the patient has orthostatic intolerance (OI). Additional criteria used for the diagnosis of OI at Vanderbilt’s Autonomic Dysfunction Center include an increase in heart rate of at least 30 beats per minute with standing, and a standing plasma norepinephrine level of at least 600 pg/ml. Because upright heart rate is usually greatly increased, the term Postural Tachycardia Syndrome (POTS) is also used. Demographics Orthostatic intolerance affects an estimated 500,000 Americans and causes a wide range of disabilities. It is a disorder that more frequently affects young women ( female-to-male ratio at least 4:1), often less than 35 years of age. Most of these patients experience an excessive heart rate increase when they stand. This heart rate increase is a sign that the cardiovascular system is working hard to maintain blood pressure and blood flow to the brain in the presence of a disordered cardiovascular regulation.

46. Copyright 1998-2004 John J. Herr, Ph.D. Please Send Comments To TITLE The postural orthostatic tachycardia syndrome a neurocardiogenic variant identified during headup tilt table testing. AUTHOR http://www.clinicalpsychologist.com/clinicalpsychologist/Collected Abstracts/Vas

National Library of Medicine: IGM Full Record Screen TITLE: The postural orthostatic tachycardia syndrome: a neurocardiogenic variant identified during head-up tilt table testing. AUTHOR: Grubb BP; Kosinski DJ; Boehm K; Kip K AUTHOR AFFILIATION: Department of Medicine, Medical College of Ohio, Toledo 43699, USA. SOURCE: Pacing Clin Electrophysiol 1997 Sep;20(9 Pt 1):2205-12 NLM CIT. ID: ABSTRACT: MAIN MESH SUBJECTS: Autonomic Nervous System Diseases/*DIAGNOSIS/DRUG THERAPY Syncope, Vasovagal/*DIAGNOSIS/DRUG THERAPY Tachycardia/*DIAGNOSIS/DRUG THERAPY ADDITIONAL MESH SUBJECTS: Adult Atenolol/THERAPEUTIC USE Erythropoietin, Recombinant/THERAPEUTIC USE Female Fludrocortisone/THERAPEUTIC USE Human Male Posture/PHYSIOLOGY Serotonin Uptake Inhibitors/THERAPEUTIC USE Tilt-Table Test PUBLICATION TYPES: JOURNAL ARTICLE LANGUAGE: Eng REGISTRY NUMBERS: (Erythropoietin, Recombinant)

47. Postural Orthostatic Tachycardia Syndrome - Encyclopedia Article About Postural Cardiac arrhythmia/tachycardia encyclopedia article about postural orthostatic tachycardia syndrome (POTS) is a form of tachycardia that occurs with a change in body position (eg, going from laying down to standing up http://encyclopedia.thefreedictionary.com/Postural orthostatic tachycardia syndr

Dictionaries: General Computing Medical Legal Encyclopedia Postural orthostatic tachycardia syndrome Word: Word Starts with Ends with Definition preview not available. Click the link for more information. Some articles mentioning "Postural orthostatic tachycardia syndrome": Acetylandromedol Albuterol Andromedotoxin Antianginal ... Tachycardia Previous Encyclopedia Browser Next Poststructuralism Poststructuralist Postsurrealism ... Pot roast Full Dictionary Browser posttraumatic amnesia posttraumatic epilepsy posttraumatic stress disorder postulant ... Postulate (enc.) Postulated Postulatio (law) postulation postulational postulator Postulatory ... Postumus (enc.) Postumus Agrippa (enc.) postural Postural asphyxia (enc.) postural hypotension Posture Posture (enc.) Posturer posturing Postvagotomy Stasis (med.) Postverta (enc.) Postville, Iowa (enc.) postwar Postzygapophysis posy POSYBL (comp.) Pot Pot (enc.) Pot (cooking) (enc.) Pot Black (enc.) pot cheese Pot companion pot farm Pot foot ... Pot hanger wiki('Postural_orthostatic_tachycardia_syndrome') For surfers: Instant word lookup for your browser Help For webmasters: Linking to the Dictionary Dictionary lookup box Script word lookup Partner with us ... Farlex, Inc.

48. Orthostatic Intolerance A Syndrome Including Neurally Mediated Intolerance a syndrome including neurally mediated hypotension, delayed orthostatic hypotension, and postural orthostatic tachycardia syndrome is found http://www.pediatricnetwork.org/medical/coexisting/cfsoi.htm

for Chronic Fatigue Syndrome, Fibromyalgia, and Orthostatic Intolerance Home News Forum Contribute ... Help Orthostatic Intolerance a syndrome including neurally mediated hypotension, delayed orthostatic hypotension, and postural orthostatic tachycardia syndrome is found in almost all adolescents with CFS: Rowe, PC. General Information Brochure on Orthostatic Intolerance and its Treatment . Chronic Fatigue Clinic, Johns Hopkins Children's Center, February 2003 Rowe, PC. Orthostatic intolerance and chronic fatigue syndrome: New light on an old problem J Pediatr. 2002 Apr;140(4):387-9. Rowe PC, Bou-Holaigah I, Kan J, Calkins H: Is neurally mediated hypotension an unrecognized cause of chronic fatigue? Lancet. 1995 Mar 11;345(8950):623-4. " We conclude that chronic fatigue syndrome is highly related to orthostatic intolerance in adolescents. The orthostatic intolerance of CFS often has heart rate and BP responses similar to responses in the syndrome of orthostatic tachycardia suggesting that a partial autonomic defect may contribute to symptomatology in these patients." ~ Julian Stewart, MD, PhD Rowe PC, Barron DF, Calkins H, Maumenee IH, Tong PY, Geraghty MT:

49. Orthostatic Intolerance Intolerance (OI) a syndrome including neurally mediated hypotension, delayed orthostatic hypotension, and postural orthostatic tachycardia syndrome, all of http://www.pediatricnetwork.org/medical/OI/

for Chronic Fatigue Syndrome, Fibromyalgia, and Orthostatic Intolerance Home News Forum Contribute ... Help Orthostatic Intolerance Pediatric Research Orthostatic Intolerance (OI): a syndrome including neurally mediated hypotension, delayed orthostatic hypotension, and postural orthostatic tachycardia syndrome, all of which are considered forms of dysautonomia Pediatric Orthostatic Intolerance Journal Articles - PubMed abstracts and full text articles when available Articles for Professionals and the General Public Introductions for the General Public Pediatric Reviews for Medical Professionals General Reviews for Medical Professionals Treatment ... More Pediatric Research Introductions for the General Public: General Information Brochure on Orthostatic Intolerance and Its Treatment by Peter C. Rowe, MD, Johns Hopkins Children's Center The diagnosis of chronic fatigue syndrome, fibromyalgia, and orthostatic intolerance in youth by Rebecca Moore Word file Orthostatic Intolerance - An introduction to the subject by David S. Bell, MD Lyndonville News May 2000 POTS Place : A Guide to Postural Orthostatic Tachycardia Syndrome Neurally Mediated Hypotension (NMH) and Chronic Fatigue Syndrome (CFS) - An interview with Peter Rowe, MD reviewing the first study to connect these two disorders in adolescents

50. Entrez PubMed postural orthostatic tachycardia syndrome (POTS) etiology, diagnosis and therapy Article in German Grubb BP, Klingenheben T. Department of Medicine http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1

51. Entrez PubMed Click here to read Asymptomatic Brugada Syndrome Associated with postural orthostatic tachycardia syndrome Morishima I, Sone T, Tsuboi H, Mukawa H, Satoda M http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1

52. STARS - Syncope Trust And Reflex Anoxic Seizures POTS Place A Guide to postural orthostatic tachycardia syndrome This web site is about a disorder called postural orthostatic tachycardia syndrome (POTS). http://www.stars.org.uk/links.html

STARS - S yncope T rust A nd R eflex anoxic S eizures Links Please Note: While we may recommend sites to you, we CANNOT be held responsible for information that you may collect from these sites. Arrhythmia Alliance Arrhythmia Alliance was launched at the start of Arrhythmia Awareness Week. We see the Arrhythmia Alliance as the obvious onward development from the AAAW, to maintain momentum, and to bring together allied parties, large and small, professional and lay, to funnel their energies toward common arrhythmia goals together. Arrhythmia Awareness Week Arrhythmia Awareness Week is a campaign that aims to improve the quality of life for people living with Cardiac Arrhythmias. Barton Hill Advice Service Barton Hill Advice Service, based in Bristol, have produced two really helpful booklets which give clear, step-by-step guidelines on how to apply for Disability Living Allowance. Contact a Family Every day over sixty children in the UK are born or diagnosed with a serious disability and the vast majority of them are cared for at home. Contact a Family (CaF) is the only UK charity providing support and advice to parents whatever the medical condition of their child. DYNAkids (Dysautonomia Youth Network of America, Inc.)

53. Inappropriate Sinus Tachycardia His first inclination is to attribute this to what is known as POTS (postural orthostatic tachycardia syndrome) which is the most current and working http://neuro-www.mgh.harvard.edu/forum/AutonomicF/12.2.978.47PMinappropriatesinu

inappropriate sinus tachycardia This article submitted by scott blanchard on 12/2/97. Email Address: lla@rincon.com My physician is not positive as to the outcome of this test because the variance in heart rate was so extreme. Most persons with POTS syndrome heart rate increases 10 to 20 bpm mine increased 45 bpm. This may be attributed to my state of physical fitness, but my physician is not positive due to a lack of current studies. I'm looking for anyone who might have any information on this syndrome and how it relates to endurance athletes. My physician has started me on a drug called Clonidine at .05 mg daily in order to try to decrease of alter my sympathetic tone. I have been on the drug for about 2 weeks and have found it to be mostly ineffective. When this condition is present, my athletic performance suffers greatly, my HR soars and my power output diminishes dramatically. My professional cycling career is in jeopardy. If anyone has any information, please contact me at lla@rincon.com or (520)629-0777. If this is to be published, please omit my name. Thank you very much for your time

54. Cardiac Arrhythmias sufficient. postural orthostatic tachycardia syndrome. Being female protects us from early atherosclerotic heart disease. However http://www.womensheartfoundation.org/content/HeartDisease/cardiac_arrhythmias.as

home about us programs press releases ... Pdf Health Library Cardiac Arrhythmia Management: Why Women are Different from Men Electrical Explanation For Gender Differences The fact that women's hearts are wired differently from men's should come as no surprise. The development of every part of the body is determined genetically, and modified by the sex hormones. The fact that we develop so similarly should really surprise us. This is also true of the electrical system of the heart in women. The way that the heart works isthrough an electrical system that we can measure on the surface with the electrocardiogram (ECG). This detects the electrical activity of the top chambers of the heart, the atria, manifest by a p wave, followed by a sharp deflection, the QRS, which represents the electrical activity of the ventricles of the heart. Following the QRS, there is a recovery interval, marked on the ECG by a hump, and the distance between the beginning of the QRS and the end of this hump, the T wave, is called the QT interval. The electrical activity we see on the surface is created by the sequential, and sometimes simultaneous, activity of a number of channels in the muscle membranes of heart tissue to allow certain ions, such a sodium, calcium, potassium, and some chemicals, such as acetylcholine, and ATP (an energy molecule) to cross into or out of the cell. The structure of these channels is determined genetically, and to some degree, their genetic expression varies with gender.

55. Inappropriate_Sinus_Tachycardia - HeartCenterOnline For Patients: Heart Health E Some people believe that the syndrome may be closely related to another rare syndrome called postural orthostatic tachycardia syndrome (POTS), which reflects http://www.heartcenteronline.com/myheartdr/common/articles.cfm?ARTID=456

56. AHMF: Guidelines Response Rowe JAMA 1940;11521627. Schondorf R, Low PA. Idiopathic postural orthostatic tachycardia syndrome An attenuated form of acute pandysautonomia? http://www.ahmf.org/g-rowe.html

Response to Guidelines for the Treatment of CFS Revised Draft 2001 Peter C. Rowe, MD Re: Revised Chronic Fatigue Syndrome Guidelines To Whom It May Concern: I have had an opportunity to review the revised Australian CFS guidelines. I am disappointed by the complete failure to integrate the scientific evidence regarding circulatory abnormalities in CFS. In a detailed letter on the draft guidelines written to Dr. Loblay in April of 1998, I discussed ways in which the guidelines might better acknowledge the association between CFS and syndromes of orthostatic intolerance. Despite the fact that many more scientific studies have emerged on this topic in the past three years, the current revision of the guidelines contains even less on orthostatic intolerance. As Wessely and colleagues emphasized in a JAMA article in 1998, the failure to integrate literature from many sources perpetuates pre-existing disciplinary biases in reviews on CFS, and an analogous failure to discuss a large literature on orthostatic intolerance in CFS affects the revised guidelines. A variety of disorders of orthostatic intolerance, most notably postural tachycardia syndrome and neurally mediated hypotension, are characterized by symptoms similar to those seen in CFS. The symptoms in common include chronic fatigue, difficulty thinking and concentrating, headaches, myalgias and chest wall pain, nausea, palpitations, and anxiety. In Jacob¼s recent study of postural tachycardia syndrome, chronic fatigue was reported by 67%. Even if one is not enthusiastic about the overall contribution of orthostatic tachycardia and hypotension to the pathophysiology of symptoms in CFS, some mention of these disorders surely belongs in any section describing the differential diagnosis of chronic fatigue.

57. AHMF: 98 Conference: Rowe been variously termed neurally mediated (or vasovagal) hypotension, delayed orthostatic hypotension, postural orthostatic tachycardia syndrome, and idiopathic http://www.ahmf.org/98rowe.html

Neurally Mediated Hypotension and CFS Peter C. Rowe, MD Dept of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Over the past half century, chronic fatigue has been described as a prominent symptom in a variety of syndromes of orthostatic intolerance. These overlapping syndromes have been variously termed neurally mediated (or vaso-vagal) hypotension, delayed orthostatic hypotension, postural orthostatic tachycardia syndrome, and idiopathic hypovolemia. Perhaps the first suggestion that these abnormalities were responsible for symptoms of what we now call chronic fatigue syndrome (CFS) was made in 1940 by MacLean and Allen. These authors described a syndrome of excessive elevation in heart rate with upright posture seemed identical to "effort syndrome, irritable heart or neurocirculatory asthenia" (JAMA 1940;115:2162-7). They recommended treatment with up to 14g of sodium per day and sleeping in a head-up position. Recent work in our center and others has emphasized a high prevalence of neurally mediated hypotension (NMH), and less commonly postural orthostatic tachycardia syndrome, in those with an established diagnosis of CFS. In a 1995 study of 23 adolescents and adults with CFS, we identified hypotension in response to a three stage 70 degree upright tilt table test in 96% of patients, versus 29% of healthy controls. During the first 45 minutes of upright tilt, 16 patients (or 70%) with CFS developed hypotension, while all controls maintained a normal blood pressure.Perhaps more importantly, all 23 with CFS but none of the controls developed orthostatic symptoms during this first stage of tilt testing, suggesting that orthostatic intolerance may be a defining feature of the illness.

58. Orthostatic Expression, Frequency per Day. orthostatic hypotension. 98. postural orthostatic tachycardia syndrome. 40. orthostatic. 15. blood orthostatic pressure. 10. http://www.websters-online-dictionary.org/definition/english/Or/Orthostatic.html

Philip M. Parker, INSEAD. Orthostatic Definition: Orthostatic Orthostatic Adjective . Pertaining to an upright standing posture; "orthostatic hypotension". Source: WordNet 1.7.1 Specialty Definitions: Orthostatic Domain Definitions Health Pertaining to or caused by standing erect. ( references Source: compiled by the editor from various references ; see credits. Top Crosswords: Orthostatic English words defined with "orthostatic" orthostatic hypotension references Specialty definitions using "orthostatic" Heptaminol Hypotension, Orthostatic Lower Body Negative Pressure Octreotide ... Top Commercial Usage: Orthostatic Domain Title References The Official Patient's Sourcebook on Orthostatic Hypotension ( reference (more reference examples) Books Orthostatic Disorders of the Circulation: Mechanisms, Manifestations, and Treatment ( reference (more book examples) Source: compiled by the editor from various references ; see credits. Top Non-Fiction Usage: Orthostatic Subject Topic Quote Health This group consists of primary writing tremor, vocal tremor, and orthostatic tremor. (

59. Postural Expression, Frequency per Day, Expression, Frequency per Day. postural orthostatic tachycardia syndrome. 40, disability hypotension postural. 3. postural hypotension. http://www.websters-online-dictionary.org/definition/english/Po/Postural.html

Philip M. Parker, INSEAD. Postural Definition: Postural Postural Adjective . Of or relating to or involving posture; "postural exercises". Source: WordNet 1.7.1 Specialty Definition: Postural Domain Definition Health Pertaining to posture or position. ( references Source: compiled by the editor from various references ; see credits. Top Crosswords: Postural Specialty definitions using "postural" cervicobrachial syndrome references Non-English Usage: Postural " is also a word in the following languages with English translations in parentheses. Danish (postural), French (postural), German (postural), Portuguese (postural), Spanish (postural). Top Commercial Usage: Postural Domain Title Books Abnormal Postural Reflex Activity Caused by Brain Lesions ( reference Exercises for Musicians: How to Control and Prevent Postural Stress ( reference Le stretching postural reference Nothing to Lose but the Pain: Without Drugs or Surgery: For Relief of Postural Pains: Foot to Jaw (Without Drugs or Surgery) ( reference Postural variations in childhood ( reference (more book examples) Source: compiled by the editor from various references ; see credits.

60. POTS Websites POTS Websites postural orthostatic tachycardia syndrome. Explanation postural orthostatic tachycardia syndrome, Patient s Report Postural Orthostatic http://www.teenagerswithchronicillnesses.freeweb-hosting.com/potswebsites.html

About me About my Illnesses Interact with Others More of my Medical Info ... Email Me POTS Websites Postural Orthostatic Tachycardia Syndrome Explanation: Postural Orthostatic Tachycardia Syndrome, Patient's Report Postural Orthostatic Tachycardia Syndrome POTS: Overview Vanderbilt University Autonomic Dysfunction Center- Orthostatic Intolerance ... POTS Information Treatment: What helps? Reducing Symptoms During Upright Posture Symptoms: Symptoms Support: Discussion Forum Meet Others Yahoo GroupsPOTS

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