Welcome! Log In Create Profile advanced search Español ... 2003 Research Conference Summary This publication is made possible by an educational grant from Amgen Summary Points/Introduction Differential Diagnosis: Idiopathic Inflammatory Myopathies Differential Diagnosis: Metabolic Myopathies ... Archives Primer on the Rheumatic Diseases, 12th edition Order Your Copy Today! Volume 51, Number 3 Myopathic Diseases Robert L. Wortmann, MD Department of Internal Medicine University of Oklahoma College of Medicine Tulsa, OK Summary Points - Skeletal muscles may be involved with inflammation or metabolic abnormalities. The clinical effects of muscle involvement include weakness, fatigue, and muscle cramping. The diagnosis is made by demonstrating muscle weakness, muscle involvement as indicated by an elevation of the CPK, an abnormality on EMG, and the pathology on muscle biopsy.
Introduction A large number of diseases and conditions affect skeletal muscle and result in symptoms ( ). These include objective muscle weakness, premature fatigue, and post-exertional aches, cramps, and pains. It is useful to classify the myopathies within several categories. The history, physical examination, serum chemistries, electrophysiologic studies (EMG), magnetic resonance imaging (MRI), and analysis of muscle tissue, but usually renders a specific diagnosis. | |
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