21. THE MERCK MANUAL, Sec. 5, Ch. 50, Diffuse Connective Tissue polymyositis And Dermatomyositis. Raynaud s phenomenon is very frequent in patients in whom polymyositis coexists with other connective tissue disorders. http://www.merck.com/mrkshared/mmanual/section5/chapter50/50i.jsp

22. THE MERCK MANUALSECOND HOME EDITION, Polymyositis And polymyositis and Dermatomyositis. polymyositis and dermatomyositis usually occur in adults from ages 40 to 60 or in children from ages 5 to 15 years. http://www.merck.com/mrkshared/mmanual_home2/sec05/ch068/ch068e.jsp

23. Arthritis Research Campaign | Polymyositis And Dermatomyositis polymyositis is a condition which affects many muscles, mainly the larger muscles of the body, such as those around the shoulders, hips and thighs. http://www.arc.org.uk/about_arth/booklets/6009/6009.htm

scotland + n. ireland north wales + midlands east + southeast ... south + southwest Introduction Inflammation of the muscles is called myositis myo = muscle, sitis = inflammation). Polymyositis is a condition which affects many muscles ( poly = many), mainly the larger muscles of the body, such as those around the shoulders, hips and thighs. This booklet also deals with dermatomyositis . This is a disease where a particular skin rash occurs ( derm = skin) with muscle inflammation that is similar to polymyositis. This booklet discusses: the nature of these conditions and the importance of getting proper treatment how many people are affected the probable causes of the conditions how doctors diagnose them and the tests used to do this treatments and possible side-effects of drug therapies current research into the conditions. It concludes by answering questions often raised by people who have polymyositis or dermatomyositis, and gives useful addresses for further information. What are the symptoms of polymyositis and dermatomyositis?

24. POLYMYOSITIS STEVE, polymyositis In late april of 1997 I was diagnosed with polymyositis. My CPK level was 7,956. It all started in mid to late http://www.rheumatic.org/steve.htm

STEVE, polymyositis In late april of 1997 I was diagnosed with polymyositis. My CPK level was 7,956. It all started in mid to late january 97 with a pain in the calf of my right leg; then aches and pains with burning muscles that got progressively worse with each passing week. Swallowing became very difficult. It was like I had the worst case of the flu ever, multiplied by a thousand. Finally I went to my GP doctor. I was tested for hepatitis, liver disease, weeks of those tests with nothing confirmed. Then I saw his associate in his absence and she wanted me to have a special test (CPK). Meanwhile a friend of mine had a bad bacterial infection that was going around and she had taken Zithromax (azithromycin) to get rid of it. I thought that was probably what I had and was sure it would help me, because my symptons were the same, only more severe. So I made a deal with the doctor - I'd go immediately for the CPK test if she would give me a prescription for Zithromax. She agreed to do that, then stated it wouldn't help. That's when I had a CPK count of 7,956. But the Zithromax did help me quite a bit. The next day I was able to lift my arms, etc.

25. POLYMYOSITIS LIANNE, polymyositis My life is my own once again! Two years ago I was diagnosed with polymyositis. I was devastated. I was a http://www.rheumatic.org/lianne.htm

LIANNE, polymyositis My life is my own once again! Two years ago I was diagnosed with polymyositis. I was devastated. I was a business owner, single parent, and a professional skater. I was so very tired, in a lot of pain, and, most of all, I feared for my life. Prior to being diagnosed I went from doctor to doctor trying to figure out what was wrong with me. I thought I was having an allergic reaction. I went to a third allergist. She interrogated me for over an hour. She ran a series of blood tests and discovered I had an elevated CPK. She confronted me assuming I was a cocaine addict and felt that must be the cause of my problem. I explained I didn't do drugs, but by the sound of the alternatives I almost wished that was the problem. I was sent to a rheumatologist. My diagnosis was confirmed by a muscle biopsy and an EMG. In that same breath that was used to give me the diagnosis, I was told that I had to have an AIDS test. I freaked. She failed to explain that the drugs she was going to prescribe were going to suppress my immune system and if I had AIDS, it would speed up my death. A psychiatrist had read to me all about being a hypochondriac, and I was told I was the healthiest looking sick person she had ever seen. When I told her how scared I was waiting for the AIDS test results, she told me, "You don't have AIDS. You had better hope you don't have polymyositis - you can die from that."

26. VSN: Spierziekten polymyositis. Wat is polymyositis? polymyositis is een chronische ziekte waarbij meerdere spieren, vooral in de bovenarmen en bovenbenen, ontsteken. http://www.vsn.nl/spierziekten/diagnose.php?diagnose_id=37

27. Polymyositis polymyositis. Definition. polymyositis is an inflammatory muscle disease causing weakness and pain. Dermatomyositis is http://www.healthatoz.com/healthatoz/Atoz/ency/polymyositis.html

Encyclopedia Index P Home Encyclopedia Encyclopedia Index P Polymyositis Definition Polymyositis is an inflammatory muscle disease causing weakness and pain . Dermatomyositis is identical to polymyositis with the addition of a characteristic skin rash. Description Polymyositis (PM) is an inflammatory disorder in which muscle tissue becomes inflamed and deteriorates, causing weakness and pain. It is one of several types of inflammatory muscle disease, or myopathy. Others include dermatomyositis (DM) and inclusion body myositis. All three types are progressive conditions, usually beginning in adulthood. A fourth type, juvenile dermatomyositis, occurs in children. Although PM and DM can occur at any age, 60% of cases appear between the ages of 30 and 60. Females are affected twice as often as males. Causes and symptoms Causes The cause of PM and DM is not known, but it is suspected that a variety of factors may play a role in the development of these diseases. PM and DM may be autoimmune diseases, caused by the immune system's attack on the body's own tissue. The reason for this attack is unknown, although some researchers believe that a combination of immune system susceptibility and an environmental trigger may explain at least some cases. Known environmental agents associated with PM and DM include infectious agents such as Toxoplasma Borrella Lyme disease bacterium), and coxsackievirus. Most cases, however, have no obvious triggers (direct causative agents). There may also be a genetic component in the development of PM and DM.

28. About Dermatomyositis And Polymyositis A General Overview This page contains an overview of dermatomyositis and polymyositis. Dermatomyositis and polymyositis. What causes polymyositis and Dermatomyositis? http://www.webhealth.co.uk/WebHealth_A-Z_of_Health/About_Dermatomyositis_And_Pol

Dermatomyositis and Polymyositis What is Myositis? Myositis is a connective tissue and autoimmune disease. The body's own immune system makes proteins called "antibodies" for protection against viruses, bacteria and other foreign bodies (antigens). In myositis the immune system is unable to tell the difference between antigens and its own cells and tissues. The immune system makes "auto-antibodies" directed against its own cells and tissues. The build up of these "auto-antibodies" in the tissues causes inflammation, pain and muscle damage. The cause of myositis is still unknown. TYPES OF MYOSITIS Polymyositis Dermatomyositis Inclusion Body Myositis Juvenile Dermatomyositis Mixed Connective Tissue MYOSITIS A GUIDE IN UNDERSTANDING THE DISEASES What is Myositis? Polmyositis and Dermatomyositis are related illnesses affecting muscle and connective tissues of the body. Joints may also occasionally be involved. A rarer form of Polymyositis is known as Localised Nodular Myositis. A more serious and rare form of myositis is Inclusion Body Myositis. In Polymyositis, the main problems are weakness and inflammation of the muscles. ('Poly' means many, 'myo' means muscle, 'itis, means inflammation.)

29. Dermatomyositis And Polymyositis They now have their own Web site at http//www.myositis.org/ . We wish them well! Classification Criteria for Dermatomyositis and polymyositis. http://132.230.36.11/neuromirror/dmpmdx.html

We formerly hosted pages from the Myositis Association of America http://www.myositis.org/ Classification Criteria for Dermatomyositis and Polymyositis Patients presenting at least one item from the first criterion and four items from the second through ninth criteria are said to have dermatomyositis. Patients presenting no items from the first criterion and at least four items from the second through ninth criteria are said to have polymyositis. Skin lesions Heliotrope rash (red purple edematous erythema on the upper palpebra) Gottron's sign (red purple keratotic, atrophic erythema, or macules on the extensor surface of finger joints) Erythema on the extensor surface of extremity joints: slightly raised red purple erythema over elbows or knees Proximal muscle weakness (upper or lower extremity and trunk) Elevated serum CK (creatine kinase) or aldolase level Muscle pain on grasping or spontaneous pain Myogenic changes on EMG (short-duration, polyphasic motor unit potentials with spontaneous fibrillation potentials) Positive anti-Jo-1 (histadyl tRNA synthetase) antibody Nondestructive arthritis or arthralgias Pathological findings compatible with inflammatory myositis (inflammatory infiltration of skeletal evidence of active regeneration may be seen.)

30. Polymyositis Note All links within content go to MayoClinic.com. Diseases and Conditions. polymyositis. A disease similar to polymyositis is dermatomyositis. http://www.cnn.com/HEALTH/library/DS/00334.html

International Edition MEMBER SERVICES The Web CNN.com Home Page World U.S. Weather ... Special Reports SERVICES Video E-mail Services CNNtoGO Contact Us SEARCH Web CNN.com In association with: INFORMATION CENTERS: Pick a category Health Centers Family Health Men's Health Women's Health Children's Health Seniors' Health Working Life Pain Management Condition Centers Immune System Allergy Alzheimer's Arthritis Respiratory System Cancer Endocrine System Digestive System Heart and Blood Infectious Disease Mental Health Note: All links within content go to MayoClinic.com Diseases and Conditions Polymyositis From MayoClinic.com Special to CNN.com Overview Polymyositis is an uncommon disease that causes inflammation in your muscles. Doctors also refer to it as a type of connective tissue disease. Its most noticeable characteristic is muscle weakness, especially in the muscles closest to your trunk, such as your shoulder and hip muscles. As a result, you may find it difficult to get out of chairs, climb stairs, brush your hair or work with your arms over your head. The disease is rarely fatal, but it can be disabling in its more severe forms. Although polymyositis can occur at any age, it mostly affects adults in their 40s and 50s. It is more common in blacks than in whites, and women have it more often than men do. The disease usually develops gradually over weeks or months.

31. Polymyositis - Medical Dictionary Definitions Of Popular Medical Terms polymyositis A chronic inflammatory disease of muscle that begins when white blood cells, the immune cells of inflammation, spontaneously invade muscles http://www.medterms.com/script/main/art.asp?articlekey=4995&rd=1

32. Polymyositis. polymyositis is a connective tissue disease that triggers inflammation and muscular weakness. The cause polymyositis. polymyositis is http://www.betterhealth.vic.gov.au/bhcv2/bhcarticles.nsf/pages/Polymyositis?Open

33. Myositis - About Myositis inflammation). Myositis refers to several different illnesses, including polymyositis, dermatomyositis, and inclusion body myositis. http://www.orthop.washington.edu/arthritis/types/myositis

Home About Us Clinics Physicians ... Contact Us A program of Table of contents About myositis What is myositis? Incidence and risk factors Prognosis ... View article with questions External links Myositis Association of America [Top] Myositis Edited by Frederick A. Matsen III, M.D. Last updated May 1, 2002 About myositis What is myositis? Myositis is the term for illnesses that involve chronic muscle inflammation ("myo" means muscle and "itis" means inflammation). "Myositis" refers to several different illnesses, including polymyositis, dermatomyositis, and inclusion body myositis. All forms of myositis involve chronic, or persistent, muscle inflammation. This muscle inflammation almost always results in weakness, and less often in heat, swelling, and pain of the muscles. Myositis can affect many parts of the body. Sometimes the joints, heart, lungs, intestines, and skin can become inflamed. Some forms of myositis, like dermatomyositis ("dermato" refers to the skin), result in particular rashes over the knuckles, around the eyes, or sometimes in other parts of the body. Other forms of myositis occur in children. Some forms are seen with other connective tissues diseases, like lupus or rheumatoid arthritis . Still other forms may occur in people with tumors. Rarely, myositis can occur in a single part of the body, such as one arm, one leg, or just the muscles that move the eye.

34. Polymyositis Diary polymyositis Adam a diary of my PM experiences (Sounds like a bad children s book, but it s the only title I could think of.) http://home.sprintmail.com/~edam/polym.html

a diary of my PM experiences (Sounds like a bad children's book, but it's the only title I could think of.) Most Recent Entry : February 2, 2004 Visit the Diary Archive for entries relating my first three years with PM, including my diagnosis. I am now in the fourth diagnosed year of living with the disease. NOTES : This page assumes a general knowledge of what myositis and polymyositis are. If you want to get the basics on this disease, visit this site I am not a medical professional, and have no medical training. This diary relates my personal experience, my conversations with my doctors, and the research I've been able to obtain from books, the internet, other myositis patients, and medical journals. If any factual inaccuracies are found, please email me and make me aware of them, so I can correct the error. How I'm Doing (for specific details, see the most recent diary entry) Medical Conditions Condition Status Polymyositis: Anti-Jo-1 Positive Active PM Related Interstitial Lung Disease Stabilizing Migraines Managed Chronic Headaches Returning* Medications Dosage Methotrexate (oral) 20 mg/week Imitrex (oral) 50 mg tablets as needed Mobic 7.5 mg 1-2 times/day as needed

35. TMA: Polymyositis polymyositis, polymyositis (POL ee my oe SIE tis). What is polymyositis? polymyositis (PM) is found mostly in people over the age of 20. http://www.myositis.org/about_myositis/polymyositis.cfm

HOME DONATE CONTACT US INTERNATIONAL ... Surveys Polymyositis HOME ABOUT MYOSITIS WHAT IS MYOSITIS Polymyositis (POL ee my oe SIE tis) What is polymyositis? What are the signs and symptoms? What tests will the doctor run to see if I have polymyositis? How is it treated? What is polymyositis? What are the signs and symptoms? Polymyositis (PM) is found mostly in people over the age of 20. More women than men have PM. PM is thought to be an autoimmune disease, meaning the body's immune system, which normally fights infections and viruses, does not stop fighting once the infection or virus is gone. The immune system then attacks the body's own normal, healthy tissue through inflammation (IN fluh MAY shun), or swelling. PM does not cause a rash. Muscle weakness usually happens over days, weeks or months. The weakness begins with muscles closest to and within the trunk of the body. Neck, hip, back and shoulder muscles are examples. Some patients also have weakness in muscles farther from the trunk, like hands and fingers. Many PM patients have trouble swallowing, or dysphagia (dis FAY jee yuh). Some patients have trouble breathing and muscle pain. What tests will the doctor run to see if I have polymyositis?

36. TMA: Home TMA funds grants TMA funds nearly $350,000 in research grants and fellowships for dermatomyositis, polymyositis, juvenile myositis and inclusionbody myositis. http://www.myositis.org/

HOME DONATE CONTACT US INTERNATIONAL ... Surveys READ MORE ABOUT: Bicycling Across America for Myositis! CONFERENCE 2004! Las Vegas - Live A Lot! This year's Annual Conference is about education and living. There will be more medical experts and new sessions focusing on: New drugs available for myositis How to improve physically and mentally Helping those who love you help you Working with your doctors Knowing your rights We are adding a more "advanced track" of sessions for those who have more experience with myositis and are seeking more detailed information. There will be opportunities to take in shows, see the sights and enjoy the fun and excitement that makes Las Vegas the liveliest city in the world. You won't want to miss being part of the action in Las Vegas this summer! Conference Program, Fees and Registration Info Reserve your rooms with the Stardust now, too! The Stardust is making rooms available for $55 Sun-Thurs; and $85 Fri-Sat; luxurious Spa Suites are available for $125. You can make your room reservations now by calling 1-800-634-6757 and providing code TMA0826.

37. Myositis (Polymyositis Dermatomyositis) Myositis (polymyositis Dermatomyositis). polymyositis involves inflammation of the muscles and can affect many parts of the body. http://www.arthritis.org/conditions/DiseaseCenter/myositis.asp

Welcome! Log In Create Profile advanced search Español ... 51 Ways to Be Good to Your Joints Myositis (Polymyositis Dermatomyositis) If your question is not answered here, please contact one of our information specialists. What Is It? Treatment Options Who Is At Risk? Resources and Suggestions ... More Information About Myositis What It It? Myositis (my-OH-sigh-tiss) is a rare disease that involves inflammation that results in damage to muscle fibers and skin. Myositis is a term that describes several illnesses including polymyositis, dermatomyositis and inclusion body myositis. Polymyositis involves inflammation of the muscles and can affect many parts of the body. When inflammation of skin involved it is called dermatomyositis Treatment Options Exercise approved by your doctor Medications: glucocorticoids; immunosuppressants Physical therapy Rest Who Is At Risk? Myositis usually affects adults between the ages of 30 and 60 and children between the ages of 5 and 15. More women than men are affected. More Information About Myositis Resources and Suggestions Visit Your Arthritis Store to request the free Myositis brochure.

38. Polymyositis -- ECureMe.com polymyositis, There is an adult form of polymyositis in those between 4060 years old, and a childhood form seen in those between ages 5-15. http://www.ecureme.com/emyhealth/data/Polymyositis.asp

DisplayAd("468","60"); Select a Health Topic ADD/ADHD Allergy Alternative Medicine Arthritis Asthma Beyond Dieting Body Aches and Pains Breast Cancer Cancer Awareness Cardio Health Children's Health Colon Cancer Contraception COPD/Emphysema Dental Health Diabetes Elder Care Emergency Room Epilepsy Erectile Dysfunction Eye Care Fertility Fitness Gastrointestinal Health Glands and Hormones Gynecologic Health Hair Loss Headache Healthcare Today Healthy Aging HIV and AIDS Infectious Diseases Kidney Health Leukemia Liver Health Lung Cancer Lymphoma Multiple Sclerosis Men's Health Mental Health Nutrition Osteoporosis Parkinson's Disease Sexual Health Skin Health Sleep Disorders Special Events Stroke Surgeries and Procedures Teen Health Thyroid Health Urologic Health Vascular Disease Women's Health Workplace Health June 2, 2004 Resource Links Physician Search Your Questions, E-mail Doctor ... Hospital Directory Polymyositis more about Polymyositis Proximal muscle weakness or Neuromyositis Polymyositis is the inflammation (i.e., irritation, pain, swelling, and damage) of the muscles closest or proximal to the trunk of the body (i.e., limb girdles, neck, and pharynx). It is a progressive condition, with periods of relapse (gets worse) and remissions (gets better). There is an adult form of Polymyositis in those between 40-60 years old, and a childhood form seen in those between ages 5-15.

39. Polymyositis MAIN SEARCH INDEX. polymyositis. Definition. polymyositis is an inflammatory muscle disease causing weakness and pain. Dermatomyositis http://www.ehendrick.org/healthy/001093.htm

MAIN SEARCH INDEX Polymyositis Definition Description Causes and symptoms Diagnosis ... Resources Definition Polymyositis is an inflammatory muscle disease causing weakness and pain . Dermatomyositis is identical to polymyositis with the addition of a characteristic skin rash. Description Polymyositis (PM) is an inflammatory disorder in which muscle tissue becomes inflamed and deteriorates, causing weakness and pain. It is one of several types of inflammatory muscle disease, or myopathy. Others include dermatomyositis (DM) and inclusion body myositis. All three types are progressive conditions, usually beginning in adulthood. A fourth type, juvenile dermatomyositis, occurs in children. Although PM and DM can occur at any age, 60% of cases appear between the ages of 30 and 60. Females are affected twice as often as males. Causes and symptoms Causes The cause of PM and DM is not known, but it is suspected that a variety of factors may play a role in the development of these diseases. PM and DM may be autoimmune diseases, caused by the immune system's attack on the body's own tissue. The reason for this attack is unknown, although some researchers believe that a combination of immune system susceptibility and an environmental trigger may explain at least some cases. Known environmental agents associated with PM and DM include infectious agents such as Toxoplasma Borrella Lyme disease bacterium), and coxsackievirus. Most cases, however, have no obvious triggers (direct causative agents). There may also be a genetic component in the development of PM and DM.

40. Diagnose-Me: Conditions: Polymyositis polymyositis, Inclusion Body Myositis is often more resistant to treatment than the usual form of disease. Signs, symptoms indicators of polymyositis http://www.diagnose-me.com/cond/C531511.html

Home FAQ Start The Analyst Last updated: May 06, 2004 Polymyositis Signs, symptoms and indicators Treatment recommendations Polymyositis is an inflammatory disease of muscle, its cause unknown. It begins when white blood cells - the immune cells of inflammation - spontaneously invade muscles. The muscles affected are mostly those closest to the trunk or torso. This in turn results in weakness which can be severe. It is a chronic illness with periods of increased symptoms, called flares or relapses, and decreased symptoms, known as remissions. Polymyositis is slightly more common in females. It affects all age groups, although its onset is most common in middle childhood and in the twenties. Polymyositis occurs throughout the world and, when associated with skin rash, is then referred to as " dermatomyositis ." It can also affect other areas of the body and is, therefore, a systemic illness. Occasionally it is associated with cancer , or with other diseases of the connective tissues (for example, systemic lupus erythematosus, scleroderma or rheumatoid arthritis To date, no cause of polymyositis has been isolated by medical researchers. There are indicators of heredity (genetic) susceptibility that can be found in some patients. There is also indirect evidence of infection by a

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