61. Bbc.co.uk - Health - Illnesses And Conditions - Polycystic Kidney A feature on polycystic kidney, what it is, its symptoms and how it can be treated. http://www.bbc.co.uk/health/conditions/polycystic_kidney.shtml

@import url('/includes/tbenh.css') ; Home TV Radio Talk ... A-Z Index THURSDAY 3rd June 2004 Text only BBC Homepage Health Home Lifestyle Home ... Conditions QUICK GUIDE A-Z Children's Ailments IN-DEPTH Addictions Allergies Arthritis Asthma ... Help Like this page? Send it to a friend! A-Z Illnesses and Conditions Polycystic Kidney Disease by Dr Trisha Macnair and Dr Rob Hicks Passed on through the family Honeycomb look Developing symptoms ... Slowing the damage In polycystic kidney disease many fluid-filled cysts develop giving the kidneys a honeycomb appearance. Far from being sweet this disease has bitter consequences. Passed on through the family PKD is one of the most common inherited disorders, and the 4th commonest cause of kidney failure. There are two types of inherited PKD. The more common type (Autosomal Dominant PKD) usually causes symptoms in midlife, although it may become apparent much younger. 90% of cases are autosomal dominant due to an abnormal gene on chromosome 16. It needs only one parent to pass on the abnormal gene giving a person a one in two chance of developing the disease later in life. The childhood form, Autosomal Recessive PKD, is much rarer. It affects about 1 in 10,000 babies - in at least some cases the gene is found on chromosome 6. It needs both parents to pass on an abnormal gene - meaning a child has a one in four chance of developing the disease in childhood. It progresses rapidly.

62. GENES INVOLVED IN POLYCYSTIC KIDNEY DISEASE SCIENCE NEWS DIGEST FOR PHYSICIANS AND SCIENTISTS, GENES INVOLVED IN polycystic kidney DISEASE polycystic kidney disease is an autosomal dominant disorder. http://www.bioscience.org/news/scientis/urine.htm

SCIENCE NEWS DIGEST FOR PHYSICIANS AND SCIENTISTS GENES INVOLVED IN POLYCYSTIC KIDNEY DISEASE Polycystic kidney disease is an autosomal dominant disorder. Worldwide, this disease accounts for 8-10% of end stage kidney disease and results in chronic renal failure in about 45% of the affected individuals by the age of 60. The patients with the disease develop cysts in both kidneys that gradually enlarge over the lifetime of the individual and ultimately lead to chronic renal failure and hypertension. At least two loci are known to exist for this disease. One locus was designated PKD4. By analysis of a genomic cosmid clone and cDNA, Lisowsky et al identified a new human gene on chromosome 16 (16p13.3) in the locus for polycystic kidney disease (PKD1). The gene contains at least one intron and is actively transcribed in tissues from kidney and brain. The predicted protein was homologous (42%) to the yeast scERV1 protein which is essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell-division cycle. A second locus is present on chromosome 4q (4q21-23). In the May 31, 1996 issue of Science, Mochizuki et al describe identification of a second gene by positional cloning, whose nonsense mutation leads to this disease. The predicted protein consists of 968 amino acids and contains six transmembrane spans with both amino- and carboxyl termini residing in the cytoplasm. This protein shows amino acid similarity to the previously described PKD1 as well as the C elegans homolog of PKD1. The protein contains one potential calcium binding site and it is interesting that there is amino acid identity between this protein and the members of the family of voltage-activated calcium and sodium channels.

63. Polycystic Kidney Disease: What Is It? Your Genes, Your Health, DNA Learning Center s multimedia guide to genetic, inherited disorders polycystic kidney disease, genetic disorder, inheritance http://www.yourgenesyourhealth.org/pkd/whatisit.htm

Concept 4 : Some genes are dominant. Find out more about dominant and recessive inheritance. Concept 5 : Genetic inheritance follows rules. Learn how Punnett squares work.

64. Polycystic Kidney Disease Important Facts about polycystic kidney Disease. polycystic kidney disease is a genetic disorder characterized by the growth of numerous cysts in the kidneys. http://www.akfinc.org/KidneyFacts/KidneyFactsContentPolycystic.htm

Important Facts Frequently Asked Questions Diabetes High Blood Pressure ... Other Links of Interest Important Facts about Polycystic Kidney Disease Polycystic kidney disease is a genetic disorder characterized by the growth of numerous cysts in the kidneys. The cysts are filled with fluid and can slowly replace much of the mass of the kidneys, reducing kidney function and leading to kidney failure. When polycystic kidney disease causes kidneys to fail - which usually happens only after many years - the patient requires dialysis or kidney transplantation. About one-half of people with the major type of polycystic kidney disease progress to kidney failure. Polycystic kidney disease can cause cysts in the liver and problems in other organs, such as the heart and blood vessels in the brain. These complications help doctors distinguish it from the usually harmless "simple" cysts that often form in the kidneys in later years of life. In the United States, about 500,000 people suffer from polycystic kidney disease, and it is the fourth leading cause of kidney failure. Medical professionals describe two major inherited forms and one non-inherited form:

65. Polycystic Kidney Disease polycystic kidney Disease. polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys. http://www.duj.com/Polycystic.html

Polycystic Kidney Disease Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys. The cysts are filled with fluid. PKD cysts can slowly replace much of the mass of the kidneys, reducing kidney function and leading to kidney failure. The kidneys are two organs, each about the size of a fist, located in the upper part of a person's abdomen, toward the back. The kidneys filter wastes from the blood to form urine. They also regulate amounts of certain vital substances in the body. When PKD causes kidneys to failwhich usually happens only after many yearsthe patient requires dialysis or kidney transplantation. About one-half of people with the major type of PKD progress to kidney failure, i.e., end-stage renal disease (ESRD). PKD can cause cysts in the liver and problems in other organs, such as the heart and blood vessels in the brain. These complications help doctors distinguish PKD from the usually harmless "simple" cysts that often form in the kidneys in later years of life. In the United States, about 500,000 people have PKD, and it is the fourth leading cause of

66. Medifocus: Polycystic Kidney Disease Guidebook MediFocus Guides Help Answer Key Questions about polycystic kidney Disease What polycystic kidney Disease. Trustworthy Information, Medifocus http://www.medifocus.com/polycystic-kidney-disease.php

Select by Specialty Cardiology Endocrinology Gastroenterology Hematology Nephrology Neurology Oncology Orthopedics Otolaryngology Psychiatry Rheumatology Or Condition Abdominal Aortic Aneurysm Acoustic Neuromas Acute Myelogenous Leukemia Ankylosing Spondylitis Atrial Fibrillation Bipolar Disorder Bladder Cancer Carcinoid Tumors Chronic Lymphocytic Leukemia Chronic Pancreatitis Cluster Headaches Ductal Carcinoma in Situ (DCIS) Glioblastoma Graves' Disease Hereditary Hemochromatosis Lymphedema Meniere's Disease Multiple Myeloma Myelodysplastic Syndromes Non-Small Cell Lung Cancer Ovarian Cancer Parkinson's Disease Peripheral Neuropathy Polycystic Kidney Disease Polycystic Ovary Syndrome Reflex Sympathetic Dystrophy Renal Cell Carcinoma Restless Legs Syndrome Scleroderma (Systemic Sclerosis) Sjogren's Syndrome Small Cell Lung Cancer Spondylolisthesis Stroke Rehabilitation Thoracic Outlet Syndrome Tongue Cancer Trigeminal Neuralgia (tic douloureux) Vertigo MediFocus Guides Help Answer Key Questions about Polycystic Kidney Disease: What are the standard treatments for Polycystic Kidney Disease? What are your treatment options?

67. Polycystic Kidney Disease polycystic kidney Disease Order the Medifocus Guidebook on polycystic kidney Disease (54 pages) Free Updates for 1 Full Year. Guidebook http://www.medifocus.com/vguide2.php?gid=NK012&a=a

68. Clinical Trial: Evaluation Of Autosomal Recessive Polycystic Kidney Disease And Evaluation of Autosomal Recessive polycystic kidney Disease and Congenital Hepatic Fibrosis. Condition. polycystic kidney, Autosomal Recessive. http://www.clinicaltrials.gov/ct/show/NCT00068224?order=3

69. Polycystic Kidney Disease - Urological Disorders Health Guide Urological Disorders. polycystic kidney Disease (PKD). What is polycystic kidney disease (PKD)? polycystic kidney disease (PKD) is http://www.umm.edu/urology-info/polycyst.htm

Urological Disorders Urogenital Disorders... Analgesic Nephropathy Cystocele ... Site Index Related Resources Within UMM Urology Urological Disorders Polycystic Kidney Disease (PKD) What is polycystic kidney disease (PKD)? Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts filled with fluid in the kidneys. PKD cysts can slowly replace much of the mass of the kidneys, reducing kidney function and leading to kidney failure. PKD can also cause cysts in the liver and problems in other organs, such as the heart and blood vessels in the brain. PKD is the fourth leading cause of kidney failure. According to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), about one-half of people with autosomal dominant PKD progress to kidney failure, or end-stage renal disease (ESRD). What are some of the types of PKD? Below you will find the description of 2 major inherited forms of PKD and one non-inherited form: autosomal dominant PKD (inherited) This is the most common inherited form of polycystic kidney disease, accounting for about 90 percent of all PKD cases. "Autosomal dominant" means that if one parent has the disease, there is a 50 percent chance that the disease will pass to a child.

70. Virtual Children's Hospital: Paediapaedia: Adult Polycystic Kidney Disease (Auto Adult polycystic kidney Disease (Autosomal Dominant polycystic kidney Disease). Michael P. D Alessandro, MD Peer Review Status Internally Peer Reviewed http://www.vh.org/pediatric/provider/radiology/PAP/GUDiseases/APCKD.html

Paediapaedia: Genitourinary Diseases Adult Polycystic Kidney Disease (Autosomal Dominant Polycystic Kidney Disease) Michael P. D'Alessandro, M.D. Peer Review Status: Internally Peer Reviewed Clinical Presentation: Normally presents in early adulthood as congestive heart failure, renal failure, and hypertension. Ten percent of cases present in first decade of life, as abdominal masses. Etiology/Pathophysiology: Multiple cysts of variable size with areas of intervening normal functioning renal parenchyma. Over time the cysts, which don't communicate with renal tubules or collecting structures, keep enlarging and continue to compress and therefore compromise the functioning renal parenchyma. Pathology: Not applicable Imaging Findings: Ultrasound and IVP shows bilateral enlarged kidneys composed of multiple large cysts of variable sizes. Forty percent have hepatic cysts, without hepatic fibrosis. Cysts are also seen in the pancreas, spleen, gonads, and lungs. Intracranial aneurysms are seen in 10%. DDX: Not applicable References: See References Chapter.

71. GeneReviews: Polycystic Kidney Disease, Autosomal Dominant Your browser does not support HTML frames so you must view polycystic kidney Disease, Autosomal Dominant in a slightly less readable form. http://www.geneclinics.org/profiles/pkd-ad/

Your browser does not support HTML frames so you must view Polycystic Kidney Disease, Autosomal Dominant in a slightly less readable form. Please follow this link to do so.

72. GeneReviews: Polycystic Kidney Disease, Autosomal Recessive Your browser does not support HTML frames so you must view polycystic kidney Disease, Autosomal Recessive in a slightly less readable form. http://www.geneclinics.org/profiles/pkd-ar/

Your browser does not support HTML frames so you must view Polycystic Kidney Disease, Autosomal Recessive in a slightly less readable form. Please follow this link to do so.

73. Polycystic Kidney Disease polycystic kidney disease,. Print this article, an inherited cystic disease of the kidneys. There are two common forms of the disease http://www.amershamhealth.com/medcyclopaedia/medical/Volume VII/POLYCYSTIC KIDNE

Amershamhealth.com Search for: Type a word or a phrase. All forms of the word are searchable. Browse entry words starting with: A B C D ... Other characters Polycystic kidney disease, an inherited cystic disease of the kidneys. There are two common forms of the disease ( polycystic kidney disease autosomal recessive ARPKD infantile polycystic kidney disease ) and autosomal dominant polycystic kidney disease (ADPKD) (also known as adult polycystic kidney disease). The gene for ADPKD is on chromosome 16, and the gene for ARPKD is on chromosome 6. Both conditions can present in the fetus or child but the recessive form is far more frequent in early childhood. In autosomal dominant polycystic kidney disease (ADPKD) there is usually a family history of the condition. The disease in children is usually diagnosed because of screening better done by gene probes than by radiology. The age of onset of cysts is very variable and normal ultrasound does not exclude the disease. The occurrence of cysts increases throughout life. Initially often the kidneys are only generally enlarged without identifiable cysts although with time cysts will appear ( Fig.1

74. Polycystic Kidney Disease, Autosomal, Dominant (adpkd) polycystic kidney disease, autosomal, dominant (adpkd),. Print this article, polycystic kidney disease, autosomal, dominant (adpkd), Fig. http://www.amershamhealth.com/medcyclopaedia/medical/Volume IV 2/POLYCYSTIC KIDN

Amershamhealth.com Search for: Type a word or a phrase. All forms of the word are searchable. Browse entry words starting with: A B C D ... Other characters Polycystic kidney disease, autosomal, dominant (adpkd), an inherited systemic disease with at least three phenotypically indistinguishable but genetically distinct entities caused by mutations in three genes, , and aortic regurgitation , bicuspid aortic valve, aortic coarctation , mitral valve regurgitation, and abdominal aortic aneurysm). Radiological findings include enlarged kidneys with multiple noncommunicating cysts ( Fig.1 Fig.2 Fig.3 Fig.4 ). Calcifications of the cyst wall can be seen. Haemorrhagic cysts are common and stones may be present. Differential diagnosis includes von Hippel Lindau disease tuberous sclerosis renal involvement , and acquired cystic disease. HH The Encyclopaedia of Medical Imaging Volume IV:2 Polycystic kidney disease, autosomal, dominant (adpkd), Fig. 1 Intravenous urography, demonstrating diffuse irregularity and splaying of the pelvicaliceal systems bilaterally, in a patient with autosomal dominant polycystic kidney disease. Polycystic kidney disease, autosomal, dominant (adpkd), Fig. 2

75. Polycystic Kidney Disease polycystic kidney Disease. polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys. http://www.stayinginshape.com/4union/libv/i71.shtml

PlaceMenu("GenInfo") PlaceMenu("Affinity") PlaceMenu("Prog") PlaceMenu("Physician") PlaceMenu("Contact") PlaceMenu("Career") PlaceMenu("Education") PlaceMenu("Newsletter") Search All Health Topics Heart Cancer Women ... En Espanol Polycystic Kidney Disease Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys. The Polycystic Kidney Disease Foundation (PKDF) calls PKD the most common genetic, life threatening disease, affecting more people than cystic fibrosis, muscular dystrophy, hemophilia, Down syndrome and sickle cell disease combined. (Read about " Cystic Fibrosis, " muscular dystrophy in " Neuromuscular Diseases, " hemophilia in " Bleeding Disorders, " " Down Syndrome " and " Sickle Cell Disease ") PKDF estimates over half a million people in the United States suffer with PKD. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) calls it the fourth leading cause of kidney failure. (Read about kidney failure in " End Stage Renal Disease ")

76. POLYCYSTIC KIDNEY DISEASE polycystic kidney DISEASE. http://www.netmedicine.com/xray/ctscan/cta22.htm

POLYCYSTIC KIDNEY DISEASE View image The axial CT scan done with intravenous contrast demonstrates the presence of bilaterally enlarged kidneys (asterisks) a solitary cyst of the polycystic kidneys is marked with the arrow heads. The left kidney demonstrates the presence of a calcified cyst wall as the result of a previous infection or hemorrhage. The presence of a fluid/fluid level within a cyst may indicate either hemorrhage or infection. NetMedicine Home Page CT Scan Library Downloading and using one of these free programs as a helper application will significantly improve JPEG image quality

77. Autosomal Dominant Polycystic Kidney Disease Autosomal Dominant polycystic kidney Disease polycystic kidney Disease. ADPKD. Book, Home Page. http://www.fpnotebook.com/REN39.htm

Home About Links Index ... Editor's Choice document.write(code); Advertisement Nephrology Failure Edema ... Edema in Chronic Renal Failure Assorted Pages Acute Renal Failure Acute Renal Failure Risk Acute Renal Failure Causes Acute Interstitial Nephritis ... Renal Disease Preoperative Care Autosomal Dominant Polycystic Kidney Disease Polycystic Kidney Disease ADPKD Book Home Page Cardiovascular Medicine Dentistry Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Nephrology Index Acid and Base Disorders Calcium Chloride Cardiovascular Medicine Dermatology Edema Endocrinology Examination Failure Glomerulus Laboratory General Pulmonology Magnesium Neurology Pharmacology Phosphorus Potassium Radiology Sodium Surgery Tubule Page Failure Index Acute Acute Risk Acute Causes Acute Causes Interstitial Nephritis Acute Causes Rhabdo Acute Causes Rhabdo Causes Acute Management Acute Postrenal Acute Prerenal Acute Prognosis Chronic Chronic Polycystic Kidneys Chronic Resources Edema Chronic Management Epidemiology Prevalence : 500,000 patients in United States

78. Polycystic Kidney Disease - Medical Dictionary Definitions Of Popular Medical Te MedicineNet Home MedTerms medical dictionary AZ List polycystic kidney disease. Advanced Search. http://www.medterms.com/script/main/art.asp?articlekey=4980

79. MayoClinic.com - Polycystic Kidney Disease More Information. polycystic kidney disease By Mayo Clinic staff Overview And having one or more kidney cysts doesn t mean you have polycystic kidney disease. http://www.mayoclinic.com/invoke.cfm?id=DS00245&

80. MayoClinic.com - Polycystic Kidney Disease polycystic kidney disease isn t limited just to your kidneys. More Information. polycystic kidney disease By Mayo Clinic staff Overview http://www.mayoclinic.com/invoke.cfm?id=DS00245

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Page 4     61-80 of 107    Back | 1  | 2  | 3  | 4  | 5  | 6  | Next 20