1. The PKD Foundation The PKD Foundation is the only organization, worldwide, devoted to improving clinical treatment and discovering a cure for polycystic kidney Disease (PKD). http://www.pkdcure.org/

2. Polycystic Kidney Disease Describes symptoms, treatment and diagnosis. http://www.niddk.nih.gov/health/kidney/pubs/polycyst/polycyst.htm

Email To A Friend Home : Polycystic Kidney Disease Polycystic Kidney Disease On this page: Autosomal Dominant PKD Autosomal Recessive PKD Acquired Cystic Kidney Disease The Search for PKD Genes ... For More Information Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys. The cysts are filled with fluid. PKD cysts can slowly replace much of the mass of the kidneys, reducing kidney function and leading to kidney failure. The kidneys are two organs, each about the size of a fist, located in the upper part of a person's abdomen, toward the back. The kidneys filter wastes from the blood to form urine. They also regulate amounts of certain vital substances in the body. When PKD causes kidneys to failwhich usually happens only after many yearsthe patient requires dialysis or kidney transplantation. About one-half of people with the major type of PKD progress to kidney failure, i.e., end-stage renal disease (ESRD). PKD can cause cysts in the liver and problems in other organs, such as the heart and blood vessels in the brain. These complications help doctors distinguish PKD from the usually harmless "simple" cysts that often form in the kidneys in later years of life. In the United States, about 500,000 people have PKD, and it is the fourth leading cause of kidney failure. Medical professionals describe two major inherited forms of PKD and a noninherited form:

3. The Polycystic Kidney Disease Information Page PKD sufferer support group. Offers links, chat room and message board. http://www.geocities.com/HotSprings/Spa/3265/

The Polycystic Kidney Disease Information Page Health News Reuter's Medical Articles Re: Kidneys Message Board Sign/View Guestbook ...  Low Protein Diet Page Click here for the text only version of this page. Old PKD Poll Results You are not alone! Polycystic Kidney Disease affects 600,000 people in the U.S. alone, and 12.5 million world wide. There are more people with PKD than cystic fibrosis, muscular dystrophy, hemophilia, Downs syndrome and sickle cell anemia combined. There are a lot of us out there! My father died of PKD in 1981 when very little information was available about this disease, even to the doctors. The nephrologist ( kidney doctor) thought he got it from his grandfather who had had medical problems and it had skipped a generation that I've since found out isn't possible. He was also never told that limiting his protein would help reduce the symptoms of uremia ( blood poisoning from kidney failure) which I think would have made his life much more comfortable. This is a big part of why I've put up this web page. I want people with PKD to be able to look up research about this disease, talk to each other, ask each other questions and be there to encourage one another. If you have PKD, please contact the

4. Polycystic Kidney Disease Defines three types of polycystic kidney disease and describes its genetic origins, symptoms, diagnosis, and treatment, as well as ongoing research. http://kidney.niddk.nih.gov/kudiseases/pubs/polycystic/

Email To A Friend Home : Polycystic Kidney Disease Polycystic Kidney Disease On this page: Autosomal Dominant PKD Autosomal Recessive PKD Acquired Cystic Kidney Disease The Search for PKD Genes ... For More Information Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys. The cysts are filled with fluid. PKD cysts can slowly replace much of the mass of the kidneys, reducing kidney function and leading to kidney failure. The kidneys are two organs, each about the size of a fist, located in the upper part of a person's abdomen, toward the back. The kidneys filter wastes from the blood to form urine. They also regulate amounts of certain vital substances in the body. When PKD causes kidneys to failwhich usually happens only after many yearsthe patient requires dialysis or kidney transplantation. About one-half of people with the major type of PKD progress to kidney failure, i.e., end-stage renal disease (ESRD). PKD can cause cysts in the liver and problems in other organs, such as the heart and blood vessels in the brain. These complications help doctors distinguish PKD from the usually harmless "simple" cysts that often form in the kidneys in later years of life. In the United States, about 500,000 people have PKD, and it is the fourth leading cause of kidney failure. Medical professionals describe two major inherited forms of PKD and a noninherited form:

5. Cat Fanciers' Association: Polycystic Kidney Disease polycystic kidney disease is an inherited kidney disease that has been found in Persian cats work needs to be done on polycystic kidney disease in cats to understand its underlying http://www.cfainc.org/health/pkd.html

Feline Health Asthma Inflammatory Bowel Disease Cat Scratch Disease Feline Immunodeficiency Virus (FIV) ... Hip Dysplasia Autosomal Dominant Polycystic Kidney Disease in Persian Cats Polycystic Kidney Disease Seminar Feline Respiratory Virus Non-obstructive Lower Urinary Tract Disease in the Cat Feline Bladder Stones and Urinary Obstructions Feline Reproduction Feline Reproduction Series Blood Type Incompatibility and Kitten Mortality Feline Care Antifreeze Warning! Chronic Gingivitis in the Cat Early Spay/Neuter in the Cat Feline Dental Pathology and Care ... Vaccination Protocols for Catteries Cats and Plants Easter Lilies Deadly to Cats Lilies Dangerous to Cats Non-Toxic Plants Toxic Plants Related Links Pet Ownership for Immunocompromised People Feline Genome Project - Genetics! for Cats Autosomal Dominant Polycystic Kidney Disease in Persian Cats David S. Biller, DVM, DACVR Associate Professor and Head of Radiology, Department of Clinical Sciences College of Veterinary Medicine, Kansas State University Stephen DiBartola, DVM, DACVIM Professor and Head of Small Animal Medicine Department of Veterinary Clinical Sciences College of Veterinary Medicine, The Ohio State University

6. Polycystic Kidney Disease polycystic kidney Disease. by Colleen Power. Is your cat drinking a lot of water? Does it visit the litter pan a bit too often? In 1978, my three year old white Persian stud began exhibiting these symptoms one day. Northington JW, Juliana MM. polycystic kidney disease in a cat http://www.netcat.org/pkd.html

$nbsp; Polycystic Kidney Disease by Colleen Power Is your cat drinking a lot of water? Does it visit the litter pan a bit too often? In 1978, my three year old white Persian stud began exhibiting these symptoms one day. Each time I passed the bathroom, there he was in the litter pan. After the third time past the door, with him back in the litter pan, I immediately thought, renal blockage. Whipped him up and over to the vet. That was not the problem. He was simply urinating too frequently. So frequently in fact that the vet called it "Polyuria." There was no blockage, no crystal formations in the bladder. He was simply urinating frequently, to the extent that within six hours, he had become dehydrated. The vet pumped him full of fluids, peritoneally(through the abdominal wall) He did x-rays to look for tumors. He then gave me the bad news. The cat likely had a progressive kidney disease that they didnt know much about, called Polycystic Kidney Disease. The cats would experience episodes of polyuria over a one year period before succumbing to the disease. Upon autopsy, they would find lesions on the kidneys, the cause was not known, but the disease was progressive, and the diagnosis: incurable. However, my cat could go home, live a happy, but short life, with increasingly frequent episodes, before he would eventually die. Supportively he received renal tablets(Renaseptic), and of course, some antibiotics. Apollo was fine for six months. I did not stress him with breedings. In fact, I was in the middle of moving and had placed nearly all of the cats, except Apollo and my two folds.

7. Polycystic Kidney Disease Image that s a link to Genetics Education Center Support Page polycystic kidney Disease. Segregation analysis of autosomal dominant polycystic kidney disease. http://www.kumc.edu/gec/support/polycyst.html

Polycystic Kidney Disease PKD Foundation (Polycystic Kidney Disease Foundation) Phone: 1-800-PKD-CURE (800.753.2873) or 816.931.2600 Fax: 816.931.8655 E-mail: pkdcure@pkdcure.org Web site: www.pkdcure.org/home.htm National Kidney Foundation 30 East 33rd Street New York, NY 10016 Phone: 800.622.9010 Web site: www.kidney.org/ Also See: National organizations - information on genetic conditions or birth defects Creating a Healthy Menu , Computer Program for Kidney Patients and Others Kidney Foundation of Canada Kidney Transplant/Dialysis Association, Inc. Australian Kidney Foundation National Kidney Research Fund , United Kingdom Other kidney disease organizations Polycystic Kidney Disease information National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health (NIDDK) Renal Family Cookbook World Kidney Fund for families in developing countries International Nephrology: Australian and New Zealand Society of Nephrology Brazilian Society of Nephrology International Society of Nephrology (ISN) International Society for Peritoneal Dialysis (ISPD) ... Renal Association (United Kingdom), for families developing countries, who have little or no access to healthcare facilities

8. Polycystic Kidney Disease Chat & Community A place where people with PKD, friends and family members can go for support. With many links for dialysis information and offers weekly chats and message boards. http://beta.communities.msn.com/PolycysticKidneydiseasechatcommunity

var nEditorialCatId = 96; MSN Home My MSN Hotmail Shopping ... Money Web Search: document.write(''); Groups Groups Home My Groups Language ... Help PolycysticKidneydiseasechatcommunity@beta.communities.msn.com What's New Join Now Members-1,839 WELCOME ... Tools Notice: Microsoft has no responsibility for the content featured in this group. Click here for more info. Try MSN Internet Software for FREE! MSN Home My MSN ... GetNetWise

9. Adult Polycystic Kidney Disease - General Practice Notebook Information with emphasis on clinical aspects. http://www.gpnotebook.co.uk/MedwebPage.cfm?ID=-1945763840

10. Resource Library Find Information On Polycystic Kidney Disease At Find information on polycystic kidney disease at MerckSource. Learn more about polycystic kidney disease, polycystic kidney disease is an inherited kidney disorder that enlarges the kidneys and http://www.mercksource.com/pp/us/cns/cns_hl_adam.jspzQzpgzEzzSzppdocszSzuszSzcns

11. Polycystic Kidney Disease - Nephrologychannel An overview of polycystic kidney disease, including a description, types, causes, diagnosis and treatment. http://www.nephrologychannel.com/polycystic/

Home Search SiteMap Ask the Dr. ... Medical Store advertisement advertisement POLYCYSTIC KIDNEY DISEASE Overview Types Causes Diagnosis ... Treatment CONDITIONS Acute Glomerulonephritis (AGN) Acute Interstitial Nephritis (AIN) Acute Renal Failure (ARF) Acute Tubular Necrosis (ATN) Anemia Chronic Renal Failure Diabetic Nephropathy Hematuria ... Nephrotic Syndrome (NS) Polycystic Kidney Disease Microalbuminuria Renal Artery Stenosis (RAS) Renal Vascular Hypertension (RVH) TREATMENT OPTIONS Hemodialysis Peritoneal Dialysis Kidney Transplant RELATED CONDITIONS Electrolyte Imbalance Hemolytic Uremic Syndrome (HUS) Thrombotic Thrombocytopenic Purpura (TTP) RESOURCES Anatomy Links Clinical Trials Videos ... What Is a Nephrologist? ABOUT US Healthcommunities.com Pressroom Testimonial Bibliography Overview Cystic kidney disease describes several conditions in which fluid-filled cysts form in the kidneys. Cysts generally develop in weak segments of the tubules that carry urine from the glomeruli. The cyst's growth displaces healthy kidney tissue. The kidneys expand to accommodate the cyst, which can weigh as much as 20 pounds. Three factors determine cyst classification: its cause (acquired, inherited), its features (complicated, simple, multiple, single), and its location (outer [cortical] or inner [medullary] kidney tissue).

12. Polycystic Kidney Disease polycystic kidney disease. Adult polycystic kidney disease (APKD) is characterized by large cysts in In 1994 the European polycystic kidney Disease Consortium isolated a gene from http://www.ncbi.nlm.nih.gov/disease/PKD.html

This Genes and Disease page has been moved to: Please update your bookmarks. If you are not automatically transported to the new page after 15 seconds, click on this link Genome View on chromosome 16 Databases PubMed the literature LocusLink collection of gene-related information OMIM catalog of human genes and disorders Information Fact sheet from the National Institute of Diabetes and Digestive and Kidney Diseases, NIH ADULT POLYCYSTIC kidney disease (APKD) is characterized by large cysts in one or both kidneys and a gradual loss of normal kidney tissue which can lead to chronic renal failure. The role of the kidneys in the body is to filter the blood, excreting the end-products of metabolism in the form of urine and regulating the concentrations of hydrogen, sodium, potassium, phosphate and other ions in the extracellular fluid. In 1994 the European Polycystic Kidney Disease Consortium isolated a gene from chromosome 16 that was disrupted in a family with APCD. The protein encoded by the PKD1 gene is an integral membrane protein involved in cell-cell interactions and cell-matrix interactions. The role of PKD1 in the normal cell may be linked to microtubule-mediated functions, such as the placement of Na(+), K(+)-ATPase ion pumps in the membrane. Programmed cell death, or apoptosis, may also be invoked in APKD. Further clarification of the pathogenesis of the disease await further research. The so-called 'cpk mouse' is a well known model for the human disease. Studying the molecular basis of the disease in the mouse is expected to provide a better understanding of the human disease, and is hoped to lead to more effective therapies.

13. Polycystic Kidney Disease a CHORUS notecard document about polycystic kidney disease Hypertext of Radiology. Kidney. Disclaimer. Feedback. Search. polycystic kidney disease. autosomal recessive ("childhood") form http://chorus.rad.mcw.edu/doc/00328.html

CHORUS Collaborative Hypertext of Radiology Kidney Feedback Search polycystic kidney disease autosomal recessive ("childhood") form: Potter I; incidence 1 : 10000 affects both kidneys and liver (related to age of onset) renal cysts periportal fibrosis neonatal +++ + infantile ++ ++ juvenile + +++ autosomal dominant ("adult") form: Potter III; incidence 1:500 no periportal fibrosis cysts in liver (in 50%), pancreas, spleen, lung berry aneurysms Charles E. Kahn, Jr., MD - 2 February 1995 Last updated 26 May 2004 Medical College of Wisconsin

14. VoyForums: Polycystic Kidney Disease Message Board Provides a forum for exchanges between individuals who suffer from polycystic kidney disease. http://www.voy.com/122978/

Contribute: Reserve your VoyUser name No-ads: Completely remove ads from your forum Owner Login VoyForums Homepage Create a New Forum VoyForums News Help Desk VoyForums Exchange FAQ - Frequently Asked Questions Directory/Categories Search VoyForums VoyUser Login VoyUser Login optional Contact Forum Admin Post a new message Check update time Archives: Polycystic Kidney Disease Message Board This message board is for people with Polycystic Kidney Disease to share information, talk about their problem and give support to one another. Feel free to post whatever you'd like to talk about. NOTICE: Please don't try to sell your kidney on this message board. I disagree with it besides also living in the U.S. where it's illegal so I will take it down. PKD Information Page Subject: Deroofing and Draining Author: Linda Edit Date Posted: 11:19:57 06/02/04 Wed Please help me in making some decisions regarding deroofing, aspiration and drainage of cysts. Mine are very large (my neph estimates that kidneys and liver are appproximately 30 lbs)and cause constant discomfort and pain. He advises against any procedures to reduce their size and is vehemently opposed to liver resection. Will any of you out there who have had procedures please share your stories with me?

15. The PKD Foundation polycystic kidney Disease is the most common genetic, life threatening disease affecting more than 600,000 Americans and an estimated 12.5 million people http://www.pkdcure.org/aboutPkd.htm

combined Polycystic means multiple cysts. In affect, PKD denotes multiple cysts on each kidney. These cysts grow and multiply over time, also causing the mass of the kidney to increase. Ultimately, the diseased kidney shuts down causing end-stage renal disease for which dialysis and transplantation are the only forms of treatment. PKD comes in two forms. Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common, affecting 1-in-400 to 1-in-500 adults. Autosomal Recessive Polycystic Kidney Disease (ARPKD) is far less common, affecting 1-in-10,000 at a far younger age, including newborns, infants and children. In this section of our Web site, you'll find a series of articles, books, audio tapes and online resources covering the basics of PKD. Attend the PKD Conference June 18 - 20, 2004 Make a Donation to help fund PKD research Become a Member of the PKD Foundation Request an Information Packet on Polycystic Kidney Disease Action Alert Help increase federal funding of PKD research Steps closer to the cure! The 2003 Walk for PKD raised more than $490,000 for research. 1-800-PKD-CURE pkdcure@pkdcure.org

16. The Polycystic Kidney Disease Links Page This page provides links to different sites that have information about polycystic kidney Disease. polycystic kidney Disease Links. http://www.geocities.com/HotSprings/Spa/3265/pkdlinks.html

Polycystic Kidney Disease Links Health News Reuter's Medical Articles Re: Kidneys Message Board Sign/View Guestbook ... Low Protein Diet Page New Links Click here to suggest a new link Links were last updated and verified June 26, 2003 Polycystic Kidney Research Foundation (PKRF) The University of Colorado PKD Research Group Has description and listing of current research studies for PKD, sign up on thier mailing list to be notified of future studies, also lists researcher and recent publications. The Institute - free or low cost scripts Government site where you can order information booklets about free or low cost prescriptions and hospital care. HDCN Highlights of the 10th Annual Conference on PKD, June 19-21, 1999. Includes "Polycystic Kidney Disease: The Basics" and "Extrarenal Manifestations of Polycystic Kidney Disease" which you can read or listen to. You do have to register with HDCN but it's free for this area. ARPKD/CHF ALLIANCE Site designed as a resource for patients, caregivers and professionals of Autosomal Recessive PKD(ARPKD) and Congenital Hepatic Fibrosis (CHF). Needymeds.com

17. MayoClinic.com - Polycystic Kidney Disease A description of the disease, and its detection and treatment. http://www.mayoclinic.com/invoke.cfm?id=DS00245&

18. Page Moved polycystic kidney Research Foundation has Moved. Please update your bookmarks now. http//www/pkdcure.org. http://www.kumc.edu/pkrf/

Polycystic Kidney Research Foundation has Moved Please update your bookmarks now http://www/pkdcure.org

19. Polycystic Kidney Disease (PKD) Describes symptoms, organs affected, treatment and diagnosis. http://familydoctor.org/142.xml

Advanced Search familydoctor.org Home Conditions A to Z Polycystic Kidney Disease (PKD) What is polycystic kidney disease? How will PKD affect me? What other organs can be hurt by PKD? What are the symptoms of PKD? ... Can PKD be diagnosed in unborn babies? Polycystic Kidney Disease (PKD) Printer-friendly version Email this article What is polycystic kidney disease? Polycystic kidney disease (PKD) is an inherited disease that affects the kidneys. Sacs of fluid (called cysts) grow in the kidneys. If too many cysts grow or if they get too big, the kidneys become damaged. The cysts may also cause pain or may get infected. PKD is the most common inherited disease in the United States. Children of parents with PKD have a 50% chance of getting the disease. Return to top How will PKD affect me? Most people with PKD can lead a normal life. In many people, the disease is mild and causes only minor problems. PKD is more severe in some patients and can cause kidney failure. About 60% of patients develop high blood pressure, which can be treated with blood pressure medicine. About 50% of patients with PKD have kidney failure by age 60. Dialysis (blood filtering) and kidney transplants are both effective treatments for kidney failure. PKD is generally worse in men, blacks and patients with sickle cell disease. There is also a childhood form of PKD which is usually more severe than the type that occurs in adults. Return to top What other organs can be hurt by PKD?

20. Polycystic Kidney Of The Kidney polycystic kidney of the Kidney From the Virtual Pathology Museum, Department of Pathology, University of Connecticut Health Center polycystic kidney, Kidney. Infantile polycystic kidney Disease http://radiology.uchc.edu/Code/640.htm

polycystic kidney, Kidney Infantile Polycystic Kidney Disease •The photograph shows renal capsule at the top with a peripheral zone of recognizable immature nephronic elements. •The cysts in the deeper parenchyma are obvious. •Cysts in infantile polycystic kidney disease are derived from the collecting ducts. This is based on nephron microdissection and immunohistochemical staining. Image Contrib. by: UCHC Description by: H. Yamase, M.D. ( 1568-8042) More Information

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