41. Pernicious Anemia -- Mechanisms Of Disease Article From New England Journal Of M This New England Journal of Medicine article provides information on pernicious anemia, the most common cause of vitamin B12 deficiency. pernicious anemia. http://content.nejm.org/cgi/content/short/337/20/1441

HOME SEARCH CURRENT ISSUE PAST ISSUES ... HELP Please sign in for full text and personal services Previous Volume 337:1441-1448 November 13, 1997 Number 20 Next Pernicious Anemia Ban-Hock Toh, M.B., B.S., D.Sc., Ian R. van Driel, Ph.D., and Paul A. Gleeson, Ph.D. Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings. Full Text PDF Letters Add to Personal Archive ... Chapters at Harrison's Pernicious anemia is the most common cause of vitamin B deficiency. Vitamin B deficiency has many causes; the term "pernicious anemia" applies only to the condition associated with chronic atrophic gastritis. A recent population survey revealed that 1.9 percent of persons more than 60 years old have undiagnosed pernicious anemia. Earlier studies suggested that pernicious anemia is restricted to Northern Europeans. However, subsequent studies have reported the disease in black and Latin-American subjects, with an earlier age of onset in black women. Although the disease is silent until the end stage, the underlying

42. September 1996 - SMJ: Gastric Cancer And Pernicious Anemia... Gastric Cancer and pernicious anemia Appearing as Pseudoachalasia. 1. Hsing AW, Hansson LE, McLaughlin JK, et al pernicious anemia and subsequent cancer. http://www.sma.org/smj/96sept13.htm

Gastric Cancer and Pernicious Anemia Appearing as Pseudoachalasia Hussein M. El-Newihi, MD, Gregory W. Dellinger, MD, Anastasios A. Mihas, MD, and James L. Achord, MD, Jackson, MS ABSTRACT: An elderly black man was admitted to our institution with macrocytic anemia, dysphagia, and significant weight loss. Results of an esophagogram were suggestive of achalasia. Gastric adenocarcinoma infiltrating the gastric cardia was seen on gastroscopy. The mode of presentation of gastric cancer in this case has not been previously reported in association with pernicious anemia. Patients with pernicious anemia are at higher risk of having gastrointestinal neoplasms than is the general population. We review the current literature and address the controversy concerning the need to subject patients with pernicious anemia to surveillance with upper gastrointestinal endoscopy. CASE REPORT Fig 1 ). The mucosa of the narrowed part was smooth, and barium entered the stomach poorly and in bursts. The possibility of achalasia of the esophagus was raised. Endoscopy of the upper GI tract showed normal esophageal mucosa and a moderately dilated esophageal lumen. The gastroesophageal junction was entered with mild resistance. A retroflexed view revealed a mass in the cardia ( Fig 2 The patient had subtotal proximal gastrectomy and distal esophagectomy with primary anastomosis and splenectomy. The tumor measured 2 cm in diameter and penetrated the gastric wall through the serosa. Ten of the 12 resected lymph nodes were involved with the neoplasm. The tumor was classified as T3, N1, M0. Subsequently, the patient received 25 sessions of external radiation delivering a total of 45 Gy, as well as 2 cycles of 5-fluorouracil and leucovorin. Within 4 months, two new masses were detected in the liver on computed tomography. The patient died of pneumonia 6 months after the initial hospital admission, with evidence of metastatic gastric adenocarcinoma.

43. Hair Loss Glossary: Pernicious Anemia Glossary. pernicious anemiaa potentially dangerous form of anemia, usually caused by an autoimmune process, which results in a deficiency of vitamin B12. http://www.hair-loss-central.com/Library/Pernicious_anemia.html

Merchant Service Search for Advanced options Home Library Hair Transplant ... Alopecia Areata Glossary Pernicious anemia a potentially dangerous form of anemia, usually caused by an autoimmune process, which results in a deficiency of vitamin B-12. © hair-loss-central.com

44. LACK OF VITAMIN B12: PERNICIOUS ANEMIA LACK OF VITAMIN B12 pernicious anemia. Report 6972. However, many people with pernicious anemia do not have abnormally low blood levels of vitamin B12. http://www.drmirkin.com/archive/6972.html

LACK OF VITAMIN B12 PERNICIOUS ANEMIA Report #6972 Pernicious anemia is due to lack of vitamin B12 and is characterized by progressive nerve damage that causes forgetfulness, loss of ability to concentrate and abnormal sensations such as burning, itching and loss of feeling. However, many people with pernicious anemia do not have abnormally low blood levels of vitamin B12. in the More Health section.). By Gabe Mirkin, M.D., for CBS Radio News Checked 12/09/03 1) J Metz, AH Bell, L Flicker, T Bottiglieri, J Ibrahim, E Seal, D Schultz, H Savoia, KM Mcgrath. The significance of subnormal serum vitamin B-12 concentration in older people: A case control study. Journal of the American Geriatrics Society 44: 11 (NOV 1996): 1355-1361. 2) Carmel R. Prevalence of undiagnosed pernicious anemia in the elderly. Archives of Internal Medicine. 1996 (May 27); 156: 1097-1100. 3) E Joosten, A Vandenberg, R Riezler, HJ Naurath, J Lindenbaum, SP Stabler, RH Allen. Am J of Clin Nutr 1993 (Oct); 58(4): 468-476. homocysteine, cystathionine, methylmalonic acid, and 2-methylcitric acid. 4) J Lindenbaum, IH Rosenberg, PWF Wilson, SP Stabler, RH Allen. American Journal of Clinical Nutrition 1994 (July); 60(1): 12-14.

45. Pernicious Anemia pernicious anemia. Definition pernicious anemia is a disease in which the red blood cells are abnormally formed, due to an inability to absorb vitamin B 12 . http://www.chclibrary.org/micromed/00060440.html

Main Search Index Definition Description Causes ... Resources Pernicious anemia Definition Pernicious anemia is a disease in which the red blood cells are abnormally formed, due to an inability to absorb vitamin B . True pernicious anemia refers specifically to a disorder of atrophied parietal cells leading to absent intrinsic factor, resulting in an inability to absorb B Description Vitamin B , or cobalamin, plays an important role in the development of red blood cells. It is found in significant quantities in liver, meats, milk and milk products, and legumes. During the course of the digestion of foods containing B , the B becomes attached to a substance called intrinsic factor. Intrinsic factor is produced by parietal cells which line the stomach. The B -intrinsic factor complex then enters the intestine, where the vitamin is absorbed into the bloodstream. In fact, B can only be absorbed when it is attached to intrinsic factor. In pernicious anemia, the parietal cells stop producing intrinsic factor. The intestine is then completely unable to absorb B . So, the vitamin passes out of the body as waste. Although the body has significant amounts of stored B

46. Diagnose-Me: Conditions: Megaloblastic Anemia / Pernicious Anemia 06, 2004. Megaloblastic Anemia / pernicious anemia, hypovitaminosis B12. Signs, symptoms indicators of Megaloblastic Anemia / pernicious anemia http://www.diagnose-me.com/cond/C364379.html

Home FAQ Start The Analyst Last updated: May 06, 2004 Megaloblastic Anemia / Pernicious Anemia Signs, symptoms and indicators Conditions that suggest it Contributing risk factors Other conditions that may be present ... anemias are somewhat rare blood disorders characterized by the presence of large, structurally and visually abnormal, immature red blood cells megaloblasts ). Decreased numbers and immaturity of white blood cells leukocytes ) and blood platelets (thrombocytes) may also occur. Megaloblastic anemias are usually caused by a deficiency or defective absorption of either vitamin B12 cobalamin ) or folic acid . As a result, they are also known as the vitamin deficiency anemias. Folic acid was discovered in 1931 as a "cure" for the anemia of pregnancy. Eating extra yeast also seemed to relieve the symptoms of pernicious anemia , but the neurological symptoms of this disease either were not resolved or appeared later on, confirming some doctors’ feelings that there were two different problems involved. In 1945, folic acid was isolated from spinach; we now know that

47. Hematology And Blood Disorders - Megaloblastic (Pernicious) Anemia Megaloblastic (Pernicious) Anemia. Megaloblastic anemia, also called pernicious anemia, is a type of anemia characterized by very large red blood cells. http://www.musckids.com/health_library/hematology/megalob.htm

Home About Us Departments Send an e-Card ... Your Hospital Visit 171 Ashley Ave. Charleston, SC 29425 800-424-MUSC Print Version Hematology and Blood Disorders Megaloblastic (Pernicious) Anemia What is megaloblastic (pernicious) anemia? Megaloblastic anemia, also called pernicious anemia, is a type of anemia characterized by very large red blood cells. In addition to the cells being large, the inner contents of each cell are not completely developed. This malformation causes the bone marrow to produce fewer cells, and sometimes the cells die earlier than the 120-day life expectancy. Instead of being round or disc-shaped, the red blood cells can be oval. What causes megaloblastic (pernicious) anemia? There are many causes of megaloblastic anemia, but the most common source in children occurs from a vitamin deficiency of folic acid. Other sources of megaloblastic anemia include the following: digestive diseases Certain diseases of the lower digestive tract can lead to megaloblastic anemia. These include celiac disease, chronic infectious enteritis, and enteroenteric fistulas. malabsorption Inherited congenital folate malabsorption, a genetic problem in which infants cannot absorb folic acid in their intestines, can lead to megaloblastic anemia. This requires early intensive treatment to prevent long term problems such as mental retardation.

48. SupportPath.com: Pernicious Anemia pernicious anemia. Other topics of interest on SupportPath.com Anemia, Nutrition. None Listed. Clinical Trials Research on pernicious anemia None Listed. http://www.supportpath.com/sl_p/pernicious_anemia.htm

Pernicious Anemia Other topics of interest on SupportPath.com: Anemia Nutrition About Us Add-A-Link ... here Online Communities / Message Boards... None Listed Online Chats... Note: Regularly scheduled chats are listed on our NEW Online Events Calendar Links in this section are primarily to chat rooms open 24/7 which may or may not be moderated. None Listed Usenet Groups... Note: Your browser must be properly configured to access Usenet groups from this site. None Listed Mailing Lists... None Listed National / International Organizations... None Listed Note: Groups are listed alphabetically by U.S. state and then country. None Listed None Listed Professional Organizations of Interest... None Listed None Listed Miscellaneous Links... None Listed Books about Pernicious Anemia and Related Topics... None Listed (The following search link is offered in association with Amazon.com Visit our Bookstore! Search: All Products Books Popular Music Classical Music Video DVD Baby Electronics Software Outdoor Living Wireless Phones Keywords: Like to add a web site to our listings? Use our Add-A-Link page.

49. Vitamin B12 Deficiency Vitamin B12 Deficiency pernicious anemia. Cobalamin Deficiency. B12 Deficiency. Book, Home Page. http://www.fpnotebook.com/HEM6.htm

Home About Links Index ... Editor's Choice document.write(code); Advertisement Hematology and Oncology Anemia Assorted Pages Anemia Anemia Clinical Clues Anemia Evaluation Macrocytic Anemia ... Pica Vitamin B12 Deficiency Pernicious Anemia Cobalamin Deficiency B12 Deficiency Book Home Page Cardiovascular Medicine Dentistry Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Hematology and Oncology Index Anemia Cancer Coagulopathy Cardiovascular Medicine Dermatology Endocrinology Otolaryngology Examination Gastroenterology Hemoglobin Hemolysis Histiocytosis HIV Infectious Disease Laboratory Leukemia General Pulmonology Lymph Marrow Neurology Obstetrics Orthopedics Pediatrics Pharmacology Platelet Prevention Procedure Psychiatry Rheumatology Sarcoma Surgery Symptom Evaluation Vascular Page Anemia Index Approach Approach Evaluation Approach Evaluation Labs Macrocytic Macrocytic Folate deficiency Macrocytic Pernicious Microcytic Microcytic Iron Deficiency Microcytic Sideroblastic Normocytic Chronic Disease Reticulocytosis See Also Macrocytic Anemia Vitamin B12 Causes: Vitamin B12 deficiency See Medications Affecting Cobalamin Pernicious Anemia Autoimmune parietal cell destruction Results in insufficient intrinsic factor production Elderly with atrophic

50. Pernicious Anemia II Introduction to Blood Morphology. pernicious anemia. pernicious anemia. Megaloblasts in the bone marrow aspirate at highoil magnification. http://eduserv.hscer.washington.edu/HuBio552/hemedist/hemecases/Intro/1004.htm

Introduction to Blood Morphology Pernicious anemia Pernicious anemia. Megaloblasts in the bone marrow aspirate at high-oil magnification. Pervading both frames is the characteristic open, beaded nuclear chromatin and nuclear- cytoplasmic disproportion. (L) The large central cell is a promegaloblast. (R) The large cell below center is a basophilic megaloblast. The two cells above are polychromatophilic megaloblasts. Return to Cases Return to Index Next Image Previous Image ... Gallery of Morphology Images

51. Pernicious Anemia Hyperseg. Macrocytosis. pernicious anemia. (L) Marked neutrophil hypersegmentation is seen in this highoil magnification field. http://eduserv.hscer.washington.edu/HuBio552/hemedist/hemecases/Intro/987.htm

Introduction to Blood Morphology Hyperseg. Macrocytosis Pernicious anemia. (L) Marked neutrophil hypersegmentation is seen in this high-oil magnification field. (R) Peripheral blood in a patient showing a large lymphocyte (top), macrocytosis and an orthochromic megaloblast (bottom). Nuclear-cytoplasmic disproportion is noted in the latter as is beaded nuclear chromatin. Return to Cases Return to Index Next Image Previous Image ... Gallery of Morphology Images

52. Pernicious Anemia - Medcohealth.com Total results found 42 documents. Your selection launched a customized search of our library of health information articles related to pernicious anemia. http://www.medcohealth.com/medco/consumer/ehealth/ehskeywordsearch.jsp?topicID=P

53. Pernicious Anemia- Medcohealth.com (See the general article anemia.) pernicious anemia is caused by a lack of intrinsic factor, a substance needed . . . pernicious anemia. Source ADAM, Inc. http://www.medcohealth.com/medco/consumer/ehealth/ehsarticle.jsp?ltSess=y&articl

54. Pernicious Anemia,Addison's Anemia,Addison-Biermer Anemia,Addisonian Pernicious pernicious anemia,Addison s Anemia,AddisonBiermer Anemia,Addisonian pernicious anemia,Primary Anemia,Congenital pernicious anemia due to Defect of Intrinsic http://www.icomm.ca/geneinfo/pernanem.htm

Pernicious Anemia,Addison's Anemia,Addison-Biermer Anemia,Addisonian Pernicious Anemia,Primary Anemia,Congenital Pernicious Anemia due to Defect of Intrinsic Factor,Gastric Intrinsic Factor Failure of Secretion,Enterocyte Cobalamin Malabsorption,Defect of Enterocyte Intrinsic Factor Receptor,Adult Onset Pernicious Anemia,Juvenile Intestinal Malabsorption of Vit B12 For Information on Workshops and Seminars for Special Needs Children click here The GAPS INDEX to Information on the Internet about Genetic Disorders and Birth Defects Genetic Information and Patient Services, Inc. (GAPS) HOME DISORDERS GLOSSARY Pernicious Anemia also known as: Addison's Anemia Addison-Biermer Anemia Addisonian Pernicious Anemia Primary Anemia Disorder Subdivisions Congenital Pernicious Anemia due to Defect of Intrinsic Factor Gastric Intrinsic Factor, Failure of Secretion Enterocyte Cobalamin Malabsorption Enterocyte Intrinsic Factor Receptor, Defect of Adult Onset Pernicious Anemia Juvenile Intestinal Malabsorption of Vit B12 (as defined by the National Organization for Rare Disorders Pernicious Anemia is a rare blood disorder characterized by the inability of the body to properly utilize vitamin B12 (a cobalamin), which is essential for the development of red blood cells.

55. Anemia, Pernicious pernicious anemia is a rare blood disorder characterized by the inability of the body to properly utilize vitamin B12 (a cobalamin), which is essential for the http://my.webmd.com/hw/health_guide_atoz/nord79.asp

var guid_source = ""; var guid_source_id = ""; //unused var encodedurl = ""; WebMD Today Home WebMD News Center Member Services WebMD University My WebMD Find a Physician Medical Info Check Symptoms Medical Library Quizzes, Calculators Clinical Trials ... Women, Men, Lifestyle Who We Are About WebMD Site Map You are in Medical Library Choose a Topic Our Content Sources Ask A Question Clinical Trials Health Guide A-Z Health Topics Symptoms Medical Tests Medications ... For a Complete Report Anemia, Pernicious Important It is possible that the main title of the report Anemia, Pernicious is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Addison's Anemia Addison-Biermer Anemia Addisonian Pernicious Anemia Primary Anemia Disorder Subdivisions Congenital Pernicious Anemia due to Defect of Intrinsic Factor Gastric Intrinsic Factor, Failure of Secretion Enterocyte Cobalamin Malabsorption Enterocyte Intrinsic Factor Receptor, Defect of Adult Onset Pernicious Anemia Juvenile Intestinal Malabsorption of Vit B12 General Discussion Pernicious Anemia is a rare blood disorder characterized by the inability of the body to properly utilize vitamin B12 (a cobalamin), which is essential for the development of red blood cells. The symptoms of Pernicious Anemia may include weakness, fatigue, an upset stomach, an abnormally rapid heartbeat (tachycardia), and/or chest pains. Recurring episodes of anemia (megaloblastic) and an abnormal yellow coloration of the skin (jaundice) are also common. Pernicious Anemia is thought to be an autoimmune disorder, and certain people may have a genetic predisposition to this disorder.

56. Vitamin B12 Deficiency Vitamin B12 Deficiency. Also indexed as pernicious anemia. nervous system. The result is pernicious anemia (PA). In the classical http://www.mycustompak.com/healthNotes/Concern/Vitamin_B12_Deficiency.htm

Vitamin B12 Deficiency Also indexed as: Pernicious Anemia Introduction Checklist Symptoms Treatments ... Vitamin B12 True PA is probably an autoimmune disease. The immune system destroys cells in the stomach that secrete intrinsic factor. Many people with PA have both chronic inflammation of the stomach lining, called atrophic gastritis, and antibodies that fight their intrinsic factor-secreting cells. The term pernicious anemia is sometimes used colloquially to refer to any anemia caused by vitamin B12 deficiency. Vitamin B12 deficiency can be due to malabsorption of dietary B12 despite normal levels of intrinsic factor. For example, celiac disease and may cause B12 malabsorption, which can lead to anemia. Less common causes of B12 deficiency include gastrointestinal surgery, pancreatic disease , intestinal parasites , and certain drugs. Pregnancy , hyperthyroidism, and advanced stages of cancer Low stomach acid , known as hypochlorhydria, interferes with the absorption of B12 from food but not from supplements. Aging is associated with a decrease in the normal secretion of stomach acid. As a result, some older people with normal levels of intrinsic factor and with no clear cause for malabsorption will become vitamin B12-deficient unless they take at least a few micrograms per day of vitamin B12 from supplements.

57. Vitamin B12 Deficiency, Pernicious Anemia The result is pernicious anemia (PA). Optional Greens + Healthy Immune and Colon Cleansing System. Also indexed as pernicious anemia. http://www.truestarhealth.com/Notes/1287007.html

Weight Loss Financial Health Truestar k i d s Encyclopedia of Health Natural Health Sport - Specific Training News Reel Online Store Gift of Health Hi ! Welcome to Truestar Health. Log In Welcome to the Truestar Health Encyclopedia Welcome to the Truestar Health Encyclopedia –the most comprehensive information database available on health, wellness, food, nutrition, vitamins and supplements. Use of our encyclopedia will enable you to make well-informed, responsible decisions for the promotion of your own health and wellness. Enter search items Vitamin B12 Deficiency Truestar Vitamin and Supplement Plans Optimal Wellness Plan Highly Recommended: TrueBASICS for Men - Optimal Wellness Pack / TrueBASICS for Women - Optimal Wellness Pack Optional: Greens + - Healthy Immune and Colon Cleansing System Also indexed as: Pernicious Anemia Introduction Checklist Symptoms Treatments ... Vitamin B12 True PA is probably an autoimmune disease. The immune system destroys cells in the stomach that secrete intrinsic factor. Many people with PA have both chronic inflammation of the stomach lining, called atrophic gastritis, and antibodies that fight their intrinsic factor-secreting cells. The term pernicious anemia is sometimes used colloquially to refer to any anemia caused by vitamin B12 deficiency. Vitamin B12 deficiency can be due to

58. Autoimmunity / What Is Autoimmunity? / Autoimmune Diseases / > Pernicious Anemia pernicious anemia is the end stage of an autoimmune gastritis resulting in destruction of the gastric mucosa. Only a small proportion http://www.diagnostics.com/templates/Page____2190.asp

Choose your destination Diagnostics Brazil Diagnostics Italy Diagnostics Netherlands Diagnostics Norway Diagnostics Spain Diagnostics Sweden Diagnostics Taiwan Diagnostics UK Diagnostics US Home Email Company Info Website Info ... Scientific Services Pernicious anemia is the end stage of an autoimmune gastritis resulting in destruction of the gastric mucosa. Only a small proportion (10-15%) of patients with autoimmune gastritis develop pernicious anemia. Nonetheless, at an estimated prevalence of 1.9% in Western adult populations at or over the age of 60 years, pernicious anemia represents the commonest cause of vitamin B12 deficiency in these populations. Although "silent" until the end stage, the gastric lesion can be predicted years before clinical presentation by immunologic markers specific for gastric autoimmunity. The gastritis results in a deficiency of intrinsic factor, a protein which binds avidly to dietary vitamin B12 and promotes its transport to the terminal ileum for absorption. Consequently, the gastritis is expressed clinically as vitamin B12 deficiency associated with megaloblastic anemia. The anemia was indeed "pernicious" when first discovered but is now readily controlled by vitamin B12 teatment.

59. MotherNature.com - Vitamin B12 Deficiency The result is pernicious anemia (PA). 1. The term pernicious anemia is sometimes used colloquially to refer to any anemia caused by vitamin B12 deficiency. http://www.mothernature.com/Library/Ency/Index.cfm/Id/1287007

Items in cart: Product Total: Add $35.00 for FREE Shipping! Welcome Shopper! Sign in or Sign up. Products Library Advanced Search Shop by Department Pet Care Sexual Health More Ways to Shop Brands A-Z Health Concern Gift Store Newsletter Sign Up Weekly health news, sale announcements and coupons! Library Home Health Concerns > Vitamin B12 Deficiency VITAMIN B12 DEFICIENCY Introduction Checklist Symptoms Treatments ... References Visit The Healthy Living Bookshelf: 21 Online Health Books From Rodale View Our Related Product Sections: Vitamin B-1 (Thiamine) Vitamin B-12 (Cobalamin) Vitamin B12 Deficiency Vitamin B12 True PA is probably an autoimmune disease. The immune system destroys cells in the stomach that secrete intrinsic factor. Many people with PA have both chronic inflammation of the stomach lining, called atrophic gastritis, and antibodies that fight their intrinsic factor-secreting cells. The term pernicious anemia is sometimes used colloquially to refer to any anemia caused by vitamin B12 deficiency. Vitamin B12 deficiency can be due to malabsorption of dietary B12 despite normal levels of intrinsic factor. For example

60. MayoClinic.com - Vitamin Deficiency Anemia An inability to absorb them in your intestines also can cause the condition. Anemia caused by an inability to absorb vitamin B12 is called pernicious anemia. http://www.mayoclinic.com/invoke.cfm?id=DS00325

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Page 3     41-60 of 99    Back | 1  | 2  | 3  | 4  | 5  | Next 20