41. Peripheral Neuropathy Ontario HIV Clinics Fact Sheet. peripheral neuropathy. What is peripheral neuropathy?peripheral neuropathy is damage to the nerves just under the skin. http://www.tthhivclinic.com/perineur.htm

INFORMATION ON HIV Go to other sections: Select a link HIV Overview/Stages of Infection The Life Cycle of HIV Disease Symptoms Fact Sheets Symptoms: Select a link Apthous Ulcers Candidiasis Cytomegalovirus (CMV) Cryptococcal Meningitis Cryptosporidiosis Herpes Zoster (Shingles) Histoplasmosis Kaposi’s Sarcoma Lymphoma Mycobacterium Avium Complex (MAC) Oral Hairy Leukoplakia PAP test/PAP smear and HIV paptest PAP test/PAP smear and HIV Peripheral Neuropathy Progressive Multifocal Leukoencephalopathy (PML) Toxoplasmosis (Toxo) Wasting Ontario HIV Clinics' Fact Sheet Peripheral Neuropathy What is Peripheral Neuropathy? Peripheral Neuropathy is damage to the nerves just under the skin. It can be caused by HIV itself and/or medications such as ddI, ddC, d4T, and some chemotherapies. What do I look for? Peripheral neuropathy may include the following symptoms: numbness and tingling of fingers, hands, toes and feet A person with these symptoms should seek medical attention. Can Peripheral Neuropathy be prevented? There is no known prevention for peripheral neuropathy.

42. Peripheral Neuropathy Articles, Support Groups, And Resources peripheral neuropathy articles, support groups, and resources for patientsfrom Med Help International (www.medhelp.org). peripheral neuropathy. http://www.medhelp.org/HealthTopics/Peripheral_Neuropathy.html

[Health Topics A-Z] A B C D ... Z Peripheral Neuropathy Medical Glossary: PERIPHERAL NEUROPATHY Ask The Doctor Forums ? Brachial Plexus surgery (Neurology and Neurosurgery Forum) Abdominal Pain with Peripheral Neuropathy (Neurology and Neurosurgery Forum) Agent Orange (Neurology and Neurosurgery Forum) AIDS related neuropathies (Neurology and Neurosurgery Forum) ... WHY DOES THE ATAXIA COME AND GO? (Neurology and Neurosurgery Forum) Support Groups: Peripheral Neuropathy Group [Med Help Home] [Library Search] [Medical Forums] ... [Patient Network] Revised: 6/2/2004

43. Peripheral Neuropathy peripheral neuropathy. What is it? The peripheral neuropathy is damage tothe nerves in the peripheral nervous system. Who gets it? Because http://www.hmc.psu.edu/healthinfo/pq/peripheralneuropathy.htm

44. N-Hexane--Related Peripheral Neuropathy Among Automotive Technicians --- Califor nHexaneRelated peripheral neuropathy Among Automotive Technicians- California, 19992000. Solvents, glues, spray paints, coatings http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5045a3.htm

n-HexaneRelated Peripheral Neuropathy Among Automotive Technicians - California, 19992000 Solvents, glues, spray paints, coatings, silicones, and other products contain normal (n-) hexane, a petroleum distillate and simple aliphatic hydrocarbon. n-Hexane is an isomer of hexane and was identified as a peripheral neurotoxin in 1964 ( ). Since then, many cases of n-hexanerelated neurotoxicity have occurred in printing plants, sandal shops, and furniture factories in Asia, Europe, and the United States ( ). This report describes an investigation of n-hexaneassociated peripheral neuropathy in an automotive technician, an occupation in which this condition has not been reported, and summarizes the results of two other case investigations in the automotive repair industry. The findings suggest that solvent manufacturers should avoid using hexane when producing automotive degreasing products, and automotive technicians should avoid regular contact with hexane-based cleaning solvents. Six (40%) of 15 technicians from this facility participated in the screening. All participants had worked

45. Peripheral Neuropathy . peripheral neuropathyis a widespread disorder, and there are many underlying causes.......MAIN SEARCH INDEX. peripheral neuropathy. http://www.ehendrick.org/healthy/001046.htm

MAIN SEARCH INDEX Peripheral neuropathy Definition Description Causes and symptoms Diagnosis ... Resources Definition The term peripheral neuropathy encompasses a wide range of disorders in which the nerves outside of the brain and spinal cordperipheral nerveshave been damaged. Peripheral neuropathy may also be referred to as peripheral neuritis, or if many nerves are involved, the terms polyneuropathy or polyneuritis may be used. Description Peripheral neuropathy is a widespread disorder, and there are many underlying causes. Some of these causes are common, such as diabetes, and others are extremely rare, such as acrylamide poisoning and certain inherited disorders. The most common worldwide cause of peripheral neuropathy is leprosy . Leprosy is caused by the bacterium Mycobacterium leprae , which attacks the peripheral nerves of affected people. According to statistics gathered by the World Health Organization, an estimated 1.15 million peoplehave leprosy worldwide. Leprosy is extremely rare in the United States, where diabetes is the most commonly known cause of peripheral neuropathy. It has been estimated that more than 17 million people in the United States and Europe have diabetes-related polyneuropathy. Many neuropathies are idiopathic, meaning that no known cause can be found. The most common of the inherited peripheral neuropathies in the United States is Charcot-Marie-Tooth disease , which affects approximately 125,000 persons.

46. Foot & Ankle Institute Diabetic peripheral neuropathy Etiology Nerves affected Diagnosingperipheral neuropathy. Etiology. Vascular Theory Decreased http://www.feetnet.com/diab/peri/

Statistics Peripheral Neuropathy Classifying Treatment ... Cases Diabetic Peripheral Neuropathy Etiology Nerves affected Diagnosing Peripheral Neuropathy Etiology Vascular Theory Decreased blood supply to the nerves leading to hypoxia of the nerve Yasuda and Dyck showed that blood vessel basement membrane was thicker in diabetics Metabolic Theory Nerve tissue is unique as it does not require insulin for glucose to be absorbed into the cells. Consequently, the glucose levels within nerve axons will be directly porportional to that of the blood. Glucose is then transformed into sorbitol and fructose which eventuallly leads to numerous biochemical and functional abnormalities. As the rate of the polyol pathway is directly dependent upon the level of glucose, persistent hyperglycemia feeds this process. Statistics Peripheral Neuropathy Classifying Treatment ... Cases

47. Best Practice Medicine- Professional Reference - Peripheral peripheral neuropathy. Diagnostic Criteria Detailed recommendations in the Report,First, determine whether the patient actually has peripheral neuropathy. more. http://merck.praxis.md/index.asp?page=bpm_brief&article_id=BPM01NE12

48. Best Practice Of Medicine - Patient Guide - Peripheral Neuropathy peripheral neuropathy. Written disrupted. Symptoms peripheral neuropathy usuallystarts with numbness and tingling in the feet or hands Table 1. http://merck.praxis.md/index.asp?page=bhg_report&article_id=BHG01NE12

49. U.S. Pharmacist Diabetic peripheral neuropathy. Minimizing and Treating Its Pain. Table 1Pain Medications for Diabetic peripheral neuropathy. Dosing Guidelines. http://www.uspharmacist.com/index.asp?show=article&page=8_996.htm

50. HealthCentral - General Encyclopedia - Peripheral Neuropathy General Health Encyclopedia, peripheral neuropathy. Causes, incidence, and riskfactors peripheral neuropathy (peripheral neuritis) is fairly common. http://www.healthcentral.com/mhc/top/000593.cfm

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51. Peripheral Neuropathy And PCBs Menu PCBs and peripheral neuropathy. Introduction; What is peripheral neuropathy;Forms and Symptoms; Diagnosis; Frequency and Causes of peripheral neuropathy. http://www.foxriverwatch.com/neuropathy_pcb_pcbs_1.html

PCB Human Health Risks Fox River Watch Site Index Make a Donation PCBs and Peripheral Neuropathy Introduction What is Peripheral Neuropathy Forms and Symptoms Diagnosis ... References

52. Peripheral Neuropathy - Information / Diagnosis / Treatment / Prevention home neurological disorders peripheral nervous system peripheral neuropathyperipheral neuropathy. Information • Diagnosis • Treatment • Prevention. http://www.healthcyclopedia.com/neurological-disorders/peripheral-nervous-system

Home Health cyclopedia All Topics by Category The Good Health Search Engine Health Conditions A-Z Gurus ... peripheral nervous system > peripheral neuropathy Peripheral Neuropathy Information / Diagnosis / Treatment / Prevention External links (marked with an arrow ) open in a new window. This site is a web directory and does not offer medical advice. We cannot take responsibility for information found on listed sites. This Page Medical Definition Health Portals Health News Web Directory: Medical Definition: University of Newcastle-upon-Tyne Medical Dictionary: "peripheral neuropathy" Health Portals: MayoClinic.com Health News: Search millions of published articles for news on Peripheral Neuropathy Modern Medicine Aging The Ardell Wellness Report HealthFacts Medical Post Medical Update Men's Health and the National Women's Health Report Note: Subscription required to access the full text of articles. Web Directory: Canadian Neuropathy Association Provides support for the people with this disorder and educates them as well as Doctors. Includes a newsletter and resources. Canadian Neuropathy Support Group Purpose is to link Canadians who suffer from any type of peripheral neuropathy or those with an interest. Includes a preview and joining instructions.

53. BrainTalk Communities - Peripheral Neuropathy Post New Thread, Page 1 of 17, 1, 2, 3, , Last ». Threads in Forumperipheral neuropathy, Forum Tools, Search this Forum. Views 3,568 http://brain.hastypastry.net/forums/forumdisplay.php?f=206

54. Peripheral Neuropathy peripheral neuropathy. peripheral neuropathy is common, affectingapproximately 20 million people in the United States. It causes http://wo-pub1.med.cornell.edu/cgi-bin/WebObjects/pops-public.woa/wa/practice?na

55. Peripheral Neuropathy peripheral neuropathy. by Mary Catherine George July 2003 What isperipheral neuropathy? Approximately 60 percent of HIV+ people http://www.thewellproject.org/Diseases_and_Conditions/Treatment_Related_Conditio

56. Peripheral Neuropathy As you may know, peripheral neuropathy is an extremely painful and sometimesdebilitating condition causing terrible agony for many people. http://www.magent.com/peripheralneuropathy.htm

Peripheral Neuropathy the strange affliction which causes pain or weakening muscles If you are searching for any of the following topics: peripheral neuropathy Look no further. You'll find it at Mag Enterprises! As you may know, peripheral neuropathy is an extremely painful and sometimes debilitating condition causing terrible agony for many people. In fact, according to a recent Roper Starch survey, upwards of 15 million are afflicted with diabetic and other neuropathies in this country. The most common problem experienced by these people is severe foot pain. Consequently adequate footwear protection and comfort is extremely important to them. Until now, there has never been a book to help those with PN. Since Numb Toes and Aching Soles: Coping with Peripheral Neuropathy, was first published this past July, it has received highly favorable reviews in over 50 health and medical publications all over the world. The February 2000 issue of the Journal of the American Podiatric Medical Association just released, for example, calls Numb Toes "a valuable resource for clinicians and peripheral neuropathy patients alike." They add that the book "should be on every podiatric physician's list of reading materials to which patients with peripheral neuropathy are referred. A comprehensive guide to help the millions with peripheral neuropathy.

57. Diabetes Library—Peripheral Neuropathies including alcoholism, diabetes mellitus, rheumatoid arthritis, systemic lupuserythematosus, amyloidosis, and uremia, may cause peripheral neuropathy. http://www.hopkinsafter50.com/html/silos/diabetes/libNeuropathies.php

books newsletter Visit our Resource Centers Anxiety Arthritis Back Pain Breast Cancer Depression Diabetes Digestive Heart Disease Hypertension Memory Nutrition Osteoporosis Prostate Stroke Vision Peripheral Neuropathies What Is It? Peripheral neuropathies are a group of disorders characterized by the degeneration of the nerves involved in the communication between the central nervous system (the brain and spinal cord) and the rest of the body. Peripheral nerves transmit sensory signals back to the central nervous system, and signals from the brain to the muscles. Neuropathies are caused by a wide variety of underlying disorders, and nerve function may be lost in a number of ways: the nerve fibers themselves (axons) may degenerate; the myelin sheaths that cover and protect the nerves may erode; and in some cases there is a loss of blood supply to a nerve. Peripheral neuropathies are most common in men between the ages of 30 and 50. Symptoms may arise from degeneration of the sensory neurons, the motor neurons, or both. Fortunately, because these disorders often leave the cell bodies of the nerves intact, the nerves can regenerate; thus, chances for recovery may be good. However, prognosis and specific treatment depend on the underlying disorder.

58. A Treatment Lesson On Peripheral Neuropathy peripheral neuropathy What Is It? peripheral neuropathy results frominjury to the peripheral nerves in the body. These nerves carry http://www.aidsmeds.com/lessons/Neuropathy1.htm

Join our confidential mailing list! Enter your email address: LESSONS COOL TOOLS DRUGS FORUMS ... HOME Peripheral Neuropathy What Is It? Peripheral neuropathy results from injury to the peripheral nerves in the body. These nerves carry signals between the central nervous system (the brain and spinal column) and the muscles, skin, and internal organs. When peripheral neuropathy first develops, people often report a tingling or prickling in the toes, although it can also start in the fingers. Over time, the tingling gradually spreads up the feet or hands and worsens into a burning, shooting, and/or throbbing pain. People who have severe peripheral neuropathy may experience extreme pain and may have difficulty walking, sometimes requiring the assistance of a cane or wheelchair to move around. People who have peripheral neuropathy usually experience symptoms on both sides of their bodies. In other words, peripheral neuropathy almost always occurs in both feet and/or both hands. The sensations can be either constant or periodic. Sometimes they may not be noticeable, while at other times they may be extremely bothersome. Peripheral Neuropathy Index What is it?

59. A Treatment Lesson On Peripheral Neuropathy peripheral neuropathy Okay, so which treatments are available? Nonnarcoticpain relievers. These include aspirin, acetaminophen http://www.aidsmeds.com/lessons/Neuropathy7.htm

Join our confidential mailing list! Enter your email address: LESSONS COOL TOOLS DRUGS FORUMS ... HOME Peripheral Neuropathy Okay, so which treatments are available? Non-narcotic pain relievers Topical medications Tricyclic antidepressants . These drugs work by reducing certain chemicals in the brain, called "neurotransmitters," that are associated with pain and emotional distress. They are often combined with non-narcotic pain relievers (see above) and are usually recommended for the treatment of mild-to-moderate pain. They are also prescribed, in combination with narcotic painkillers, to help manage severe pain. While anecdotal (word-of-mouth) reports from HIV-positive patients and doctors suggest that tricyclic antidepressants are sometimes helpful in managing symptoms of peripheral neuropathy, data from clinical trials are either limited or have not shown that these drugs are, in fact, effective. Anticonvulsants . Anticonvulsants are normally used to treat epilepsy, another neurological disorder. These drugs help calm the central nervous system, including the part of the nervous system responsible for processing pain. While anecdotal (word-of-mouth) reports from HIV-positive patients and doctors suggest that anticonvulsants are sometimes helpful in managing symptoms of peripheral neuropathy, data from clinical trials are either limited or have not shown that these drugs are, in fact, effective.

60. SF AIDS Fdn: BETA 3/97 -- Peripheral Neuropathy This article from the March 97 Bulletin of Experimental Treatments for AIDS coversperipheral neuropathy, which affects primarily the sense of touch in the http://www.sfaf.org/treatment/beta/b32/b32pn.html

Published in the Bulletin of Experimental Treatments for AIDS March 1997 issue, by the San Francisco AIDS Foundation. March 1997 Table of Contents Main Page beta@sfaf.org Peripheral Neuropathy by Mark Bowers The ancient Greeks were the first to enumerate the 5 senses: vision, hearing, taste, smell and touch. Aristotle further divided the sense of touch into hard-soft, hot-cold and rough-smooth components, quite similar to the findings of modern neurological research that supports the existence of different types of peripheral nerves in the body that carry the sensations of cold, warmth, touch and pain. HIV infection is associated with several kinds of peripheral neuropathy that affect primarily the sense of touch in the hands and feet, but may also cause more severe symptoms such as muscle weakness. HIV does not directly infect neurons (nerve cells). Instead, it may damage the cells that surround nerves, unraveling neural insulation and slowing, garbling or stopping the transmission of information to and from the brain. Abnormal macrophage activation is associated with the pathology. Some of the drugs that are used to treat HIV or associated opportunistic infections (OI) may damage axons, the long, narrow connecting processes of neurons that communicate with muscles, tissues and organs. Symptoms of peripheral neuropathy may arise at any time during HIV infection. Neuropathy is reported at a rate of 6-8% during the acute retroviral syndrome that often occurs shortly after infection. Neuropathy may affect people with asymptomatic HIV disease, manifesting in syndromes ranging from mononeuritis (inflammation of a single nerve) and mononeuropathy (disease of a single nerve), to polyneuropathies that affect multiple nerves and can lead to paralysis. Most commonly, peripheral neuropathy develops in people with symptomatic HIV disease or AIDS. For these individuals, the symptoms of painful, burning feet or numbness in the feet and/or hands are familiar and often disabling.

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