61. Peptic Ulcers peptic ulcers, Facts About Stomach and Duodenal Ulcers During normal cases. Factors in the development of peptic ulcers Factors http://careconnection.osu.edu/diseasesandconditions/healthtopics/digestive/pepti

Health Topics Cancer Diabetes Digestive Disorders ... Healthcare Services view print friendly page Health Topics Digestive Disorders Peptic Ulcers Peptic Ulcers Facts About Stomach and Duodenal Ulcers During normal digestion, food moves from the mouth down the esophagus into the stomach. The stomach produces hydrochloric acid and an enzyme called pepsin to digest the food. From the stomach, food passes into the upper part of the small intestine, called the duodenum, where digestion and nutrient absorption continue. An ulcer is a sore or lesion that forms in the lining of the stomach or duodenum where hydrochloric acid and pepsin are present. These ulcers are referred to as peptic ulcers gastric ulcers in the stomach and duodenal ulcers in the duodenum. About one in 10 Americans develop at least one ulcer during their lifetimes. Ulcers affect about five million people each year. More than 40,000 people each year have surgery because of persistent symptoms or problems from ulcers. Each year, nearly 6,000 people die of ulcer-related complications. Ulcers can develop at any age, but they are rare among teenagers and even more uncommon in children.

62. EMedicine Health - Peptic Ulcers Overview You are in Esophagus, Stomach, and Intestine, peptic ulcers, Overview, peptic ulcers are a very common condition in the United States and throughout the world. http://www.emedicinehealth.com/articles/10619-1.asp

Search June 2, 2004 Registration Healthcare Professionals High cholesterol can affect children. Is your child at risk? About 1 million people in the United States have Crohn disease. What are treatment options? Is there a connection between IBD and Crohn Disease? About one third of those with diabetes do not know they have it. Are you one? Two million or more Americans have schizophrenia. Is someone you love affected? One third of those with asthma are children. What are the symptoms and triggers? Asthma Cholesterol Crohn Disease Diabetes ... Mental Health You are in: Esophagus, Stomach, and Intestine Peptic Ulcers Overview In the digestive system, an ulcer is an area where tissue has been destroyed by gastric juices and stomach acid. Peptic ulcer disease is a general term for ulcers that occur in the stomach or duodenum (upper part of the small intestine). A peptic ulcer is an erosion or sore in the wall of the gastrointestinal tract. The mucous membrane lining the digestive tract erodes and causes a gradual breakdown of tissue.

63. Peptic Ulcers - Everybody - New Zealand Consumer Health Information peptic ulcers. What are they? peptic ulcers are small holes in the lining of your stomach or gut. There are several types and they http://www.everybody.co.nz/docsi_p/peptreat.htm

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64. Peptic Ulcer Peptic Ulcer. Those in the duodenum are called duodenal ulcers. In general, ulcers in the stomach and duodenum are referred to as peptic ulcers. http://www.diet-and-health.net/Diseases/PepticUlcer.html

Go Back Nutrition for a Living Planet - Home Page Peptic Ulcer During normal digestion, food moves from the mouth down the esophagus into the stomach. The stomach produces hydrochloric acid and an enzyme called pepsin to digest the food. From the stomach, food passes into the upper part of the small intestine, called the duodenum, where digestion and nutrient absorption continue. An ulcer is a sore or lesion that forms in the lining of the stomach or duodenum where acid and pepsin are present. Ulcers in the stomach are called gastric or stomach ulcers. Those in the duodenum are called duodenal ulcers. In general, ulcers in the stomach and duodenum are referred to as peptic ulcers. Ulcers rarely occur in the esophagus or in the first portion of the duodenum, the duodenal bulb. About 20 million Americans develop at least one ulcer during their lifetime. Ulcers can develop at any age, but they are rare among teenagers and even more uncommon in children. Duodenal ulcers occur for the first time usually between the ages of 30 and 50. Duodenal ulcers occur more frequently in men than women. For almost a century, doctors believed lifestyle factors such as stress and diet caused ulcers. Later, researchers discovered that an imbalance between digestive fluids (hydrochloric acid and pepsin) and the stomach's ability to defend itself against these powerful substances resulted in ulcers. Today, research shows that most ulcers develop as a result of infection with bacteria called Helicobacter pylori (H. pylori). While all three of these factorslifestyle, acid and pepsin, and H. pyloriplay a role in ulcer development, H. pylori is now considered the primary cause.

65. P991019a - Peptic Ulcer, Steroid-induced Peptic Ulcer, Steroidinduced. This study strongly suggests that corticosteroids do increase the risk of peptic ulcers and gastrointestinal hemorrhage. 4 . http://www.emory.edu/WHSCL/grady/amreport/litsrch99/p991019a.html

Peptic Ulcer, Steroid-induced 10/19/99 (Doyle) Group: Tuesday Interns RE: 48 year old female with 30 year history of lupus, who presented with stomach pain. Question: Is there such a thing as steroid-induced peptic ulcer disease? Unique Identifier: 95081753 Authors: Conn HO. Poynard T. Institution: Yale University School of Medicine, West Haven, Connecticut. Title: Corticosteroids and peptic ulcer: meta-analysis of adverse events during steroid therapy [see comments]. Source: Journal of Internal Medicine. 236(6):619-32, 1994 Dec. Unique Identifier: 83219151 Authors: Messer J. Reitman D. Sacks HS. Smith H Jr. Chalmers TC. Institution: None Title: Association of adrenocorticosteroid therapy and peptic-ulcer disease. Source: New England Journal of Medicine. 309(1):21-4, 1983 Jul 7. Unique Identifier: 76100718 Authors: Conn HO. Blitzer BL. Institution: None Title: Nonassociation of adrenocorticosteroid therapy and peptic ulcer. [Review] [65 refs] Source: New England Journal of Medicine. 294(9):473-9, 1976 Feb 26. Morning Report Emory University School of Medicine 1999 Edition Participating Faculty: Daniel Stephens MD / Donald Brady MD dbrady@emory.edu

66. Digestive Reading 4 Peptic Ulcer Approximately 5% to 12% of the population is affected by peptic ulcers. Most cases of peptic ulcer are apparently due http://www.mhhe.com/biosci/ap/seeleyap/digestive/reading4.mhtml

Peptic Ulcer Approximately 5% to 12% of the population is affected by peptic ulcers. Most cases of peptic ulcer are apparently due to the infection of a specific bacterium Helicobacter pylori. it is also thought that the bacterium is involved in many cases of gastritis and gastric cancer. Conventional wisdom has focused for years on the notion that stress, diet, smoking, and/or alcohol cause excess acid secretion in the stomach, resulting in ulcers. Even today, antacids are used to treat 90% of all ulcers, with $4.4 billion spent on antacids in the United States during 1992. Antacid therapy does relieve the ulcer in most cases. However, with antacid treatment, there is a 50% incidence of relapse within 6 months and a 95% incidence of relapse after 2 years. On the other hand, studies using antibiotic therapy in addition to bismuth and ranitidine have demonstrated a 95% eradication of gastric ulcers and 74% of duodenal ulcers within 2 months. Dramatically reduced relapse rates have also been obtained. One such study reported a recurrence rate of 8% following antibiotic therapy, compared to recurrence rate of 86% in controls. The infection rate from H. pylori in the United States population is about 1% per year of age: 30% of people that are 30 years old have the bacterium and 80% of those age 80 are infected. In third-world countries, as many as 100% of people age 25 or older are infected. This may relate to the high rates of stomach cancer in some of those countries. We still have much to learn in understanding this bacterium. Very little is known concerning how people become infected. Also, with such high rates of infection it is not known why only a small fraction of those infected actually develop ulcers. It may be that the factors listed predispose a person who is infected by the bacterium to actually develop an ulcer.

67. HealthWorld Online - Medical Self-Care -, HealthWorld Online - Natural Health An Zen. peptic ulcers. © American Institute of Preventive Medicine. Eighty to 90 percent of the time, peptic ulcers recur within two years of the initial attack. http://www.healthy.net/asp/templates/article.asp?PageType=article&ID=1848

68. Dr. Rose's Peripheral Brain--PEPTIC ULCER DISEASE AND RELATED DISORDERS 82 pts with H. pyloriass d bleeding peptic ulcers, all of whom underwent successful H. pylori eradication and 3 additional weeks of omeprazole 20mg QD http://faculty.washington.edu/momus/PB/pepticul.htm

PEPTIC ULCER DISEASE I. Definitions: "Erosion" = focal area of mucosal loss w/o extension to submucosa; "Ulcer" = ditto w/extension to submucosa; "Peptic Ulcer" = ulcer in stomach or duodenum II. Epidemiologic aspects of peptic ulcer disease Lifetime incidence of 10%; prevalence of 1-2% DU Men:Women 2:1 1.5 times as common as gastric ulcer Peak incidence for DU is in 5th decade in men and 6th decade in women Almost always in duod. bulb or immed. postbulbar; if further distal, think Z-E or Crohn's!! Not associated with cancer Gastric ulcer More common among elderly Us. located on lesser curvature, at jn. between body and antrum 1-3% of gastric ulcers occur in cancers III. Risk factors/Causes Male sex First degree relative with DU (RR about 3.0) H. pylori Infection Found in 90% of pts with duodenal ulcers and 60-80% of pts with gastric ulcers; successful eradication reduces risk of ulcer recurrence Genetic markers Elevated pepsinogen 1 levels HLA-B5 Decreased RBC acetylcholinesterase Cigarette smoking Zollinger-Ellison Syndrome Chronic renal failure (DU only) COPD (DU only) Alcoholic Cirrhosis (DU only) Hyperparathyroidism NSAIDs including ASA Cause GU and, to a lesser degree, DU

69. GENERALIZED ANXIETY DISORDER In recent years, attention has focused on a more biological element with the identification of bacteria as a cause of peptic ulcers. http://www.hbns.org/news/anxiety11-25-02.cfm

LINKED TO PEPTIC ULCER DISEASE Release Date: Nov. 25, 2002 GENERALIZED ANXIETY DISORDER LINKED TO PEPTIC ULCER DISEASE By Ann Quigley, Contributing Writer Health Behavior News Service A new finding of a link between an anxiety disorder and peptic ulcer disease lends support to the view that this gastrointestinal disease and anxiety disorder may share a common link. In recent years, attention has focused on a more biological element with the identification of bacteria as a cause of peptic ulcers. "The identification of Helicobacter pylori as an infectious cause of peptic ulcer disease has been considered by many to disprove the possibility that there is an important relationship between anxiety disorders and gastrointestinal disease," says study author Renee D. Goodwin, Ph.D., from the Department of Epidemiology at the Mailman School of Public Health at Columbia University in New York City. "Over the last several years research on the causes and treatments for peptic ulcer disease has neglected the links with psychiatric/psychological factors," she notes. Goodwin and co-author Murray B. Stein, M.D., from the Department of Psychiatry at the University of California at San Diego in California, analyzed data from the National Comorbidity Survey, a household survey of U.S. individuals aged 15 to 54, to determine the relationship between generalized anxiety disorder and ulcers.

70. About GERD NSAIDs and peptic ulcers NIH Publication No. Most peptic ulcers are caused by infection with the bacterium Helicobacter pylori (H. pylori). http://www.aboutgerd.org/NSAID.html

About GERD Characteristics Treatment Daily Living ... Contact IFFGD Visit these IFFGD web sites: IFFGD.org About IFFGD GI Disorders Publications ... aboutKidsGI.org N SAIDs and Peptic Ulcers A peptic ulcer is a sore that forms in the lining of the stomach or the duodenum (the beginning of the small intestine). An ulcer can cause a gnawing, burning pain in the upper abdomen; nausea; vomiting; loss of appetite; and weight loss. Most peptic ulcers are caused by infection with the bacterium Helicobacter pylori H. pylori ). But some peptic ulcers are caused by prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs) or pain relievers such as aspirin, ibuprofen, and naproxen sodium. NSAIDs cause ulcers by interfering with the stomach's ability to protect itself from acidic stomach juices. Normally the stomach has three defenses against digestive juices: mucus that coats the stomach lining and shields it from stomach acid, the chemical bicarbonate that neutralizes stomach acid, and blood circulation to the stomach lining that aids in cell renewal and repair. NSAIDs hinder all of these protective mechanisms, and with the stomach's defenses down, digestive juices can damage the sensitive stomach lining and cause ulcers. NSAID-induced ulcers usually heal once the person stops taking the medication. To help the healing process and relieve symptoms in the meantime, the doctor may recommend taking antacids to neutralize the acid and drugs called H2-blockers or proton-pump inhibitors to decrease the amount of acid the stomach produces.

71. MUSC Digestive Disease Center - Basic Science Peptic Ulcer Disease. peptic ulcers are sores or lesions of the stomach or duodenal lining which form in the presence of acid and pepsin. http://www.ddc.musc.edu/ddc_pro/pro_development/basic_science/peptic.htm

Basic Science A Brief Overview of New Developments Introduction Gallstones Gastroesophageal Reflux Disease Inflammatory Bowel Disease ... Obesity Research Group Peptic Ulcer Disease Peptic ulcers are sores or lesions of the stomach or duodenal lining which form in the presence of acid and pepsin. The primary cause of ulcer formation is infection of the stomach by bacteria called Helicobacter pylori H. pylori infection is confirmed by a blood test, breath test, or tissue test. Treatment focuses on eradication of H. pylori by antibiotics, reduction of acid production by H2 blockers and proton pump inhibitors, and restitution of mucosal defences by sucralfate and by misoprostol, a prostaglandin which stimulates mucus and bicarbonate secretion. An NIH panel recommends a 2-week, triple therapy of metronidazole, tetracycline or amoxicillin, and bismuth subsalicylate for efficient eradication of H. pylori The most significant research accomplishment within the last year in the field of peptic ulcer was the sequencing of the entire genome of H. pylori

72. Medical And Health, Celebrex, Peptic Ulcers, Arthritis peptic ulcers peptic ulcers Not too long ago, peptic ulcers were thought to be caused by stress, spicy foods, plus other risk factors that caused or helped http://www.doublenickels.com/page41.html

HOME CONTACT US ADVERTISING MEMBERSHIP ... GENEALOGY PEPTIC ULCERS Peptic Ulcers Not too long ago, Peptic Ulcers were thought to be caused by stress, spicy foods, plus other risk factors that caused or helped contribute to the condition. For instance, too much coffee, tea, chocolate, smoking and alcohol. Thanks to some Australian Researchers we now know that most Peptic Ulcers are actually caused by a bacterial infection. Please be aware that this is relatively new, and some misleading and simply out dated pamphlets that are still in circulation (Save-On Drugs /1992). This bacterial infection is called H. pylori - (Helicobacter pylori) that infects the stomach. This infection is common throughout the world, and Its been suggested that it could of even been acquired as far back as your childhood. Usually, people infected have no symptoms, and develop no problems as a result. However, about 10 to 15 percent of the people infected with H. pylori will eventually develop a peptic ulcer. There are two types of peptic ulcers: Gastric Ulcers : Occurs in the stomach. This type affects people of all ages, but most frequently affects people our age (55 to 65

73. BioSpace News: Peptic Ulcer Testing For Stomach Bacteria Doesn t Help With peptic ulcers Routine testing and treatment for the Helicobacter pylori bacteria in people with suspected peptic http://www.biospace.com/news_rxtarget.cfm?RxTargetID=95

74. Cleveland Clinic > Gastroenterology > Swallowing > Patient Information > Peptic What Causes peptic ulcers? Stress, personality, occupation, alcohol consumption, and diet all have no relationship to the development of peptic ulcers. http://www.clevelandclinic.org/gastro/swallowing/patient/peptic.htm

Achalasia Esophageal Cancer Heartburn Hiatal Hernia ... Swallowing Disorders Peptic ulcer disease (gastric ulcer and duodenal ulcer) is a common health problem. Approximately 20 million Americans will suffer from an ulcer once in their lifetime. What is a Peptic Ulcer? What Causes Peptic Ulcers? Peptic ulcer disease was once thought of simply as a problem of too much acid and stress. However, it is now clear that an ulcer is the end result of an imbalance between digestive fluids (hydrochloric acid and pepsin) in the stomach and duodenum. Much of that imbalance is clearly related to infection with the bacteria Helicobacter pylori (H. pylori). The other major risk factor for the development of ulcers is ingestion of nonsteroidal antiinflammatory drugs (NSAIDs) such as aspirin, buffered aspirin, naproxen (Aleve, Anaprox, Naprosyn, etc.) and ibuprofen (Motrin, Advil, Midol, etc.). The risk of NSAID-induced ulceration is dose-related and increases with: use of corticosteroids and NSAIDs together length of time taking NSAIDs a history of ulcer disease The following serious complications associated with patients taking NSAIDs occur without warning: bleeding perforation (a hole through the lining of the stomach) gastric outlet obstruction (scarring that blocks the passageway leading from the stomach to the small intestine) Risk factors for developing these serious complications are: a history of peptic ulcer disease, bleeding ulcers or cardiovascular disease

75. Peptic Ulcers - Health - Indiatimes peptic ulcers. A necessary. Often a patient with classic symptoms suggestive of peptic ulcer disease will have another cause for the pain. http://health.indiatimes.com/articleshow/1159088.cms

var strchannel = 'Health'; var strpagetitle = 'Health'; var strfont = ''; var strlink = ''; var strendlink = ''; var bspeedera = false; var bloginbased = true; var bsinglelineformat = false; var strloginip = 'http://Health.indiatimes.com'; var strlogoutip='http://Health.indiatimes.com/logout.asp'; Search Indiatimes Web Indiatimes Illness Home Sections Sexual Health Mental Health Alternative Therapies Fitness ... Nutrition Illness Spiritual Health Special Centres Doctors Speak Features ... Health Care Interactive Ask The Expert Health Forums Fitness Tools Pregnancy Tools ... Clubs Peptic Ulcers A peptic ulcer is a chronic sore or crater extending through the protective mucous membrane lining and penetrating the underlying muscular tissue of the gastrointestinal tract. An ulcer can form in any area exposed to gastric acid and pepsin, a digestive enzyme instrumental in the breakdown of protein and hence the derivation of the term "peptic ulcer." The areas most commonly affected are: the upper-part of the duodenum (duodenal ulcer) the stomach itself (gastric ulcer) the oesophagus Causes: In a healthy person, there is a balance between factors that cause ulcers and factors that prevent ulcers. Most important among these factors are the amount of acid and pepsin the stomach secretes, especially the former, and the ability of the lining of the stomach and duodenum to resist the erosive action of the acid and pepsin. An ulcer develops when the balance between these factors is upset for some reason.

76. Treatment Of Peptic Ulcers At Mayo Clinic Mayo Clinic Medical Services peptic ulcers. Treatment of peptic ulcers at Mayo Clinic. (Synonyms stomach ulcers, duodenal ulcers). peptic ulcers are common. http://www.mayoclinic.org/pepticulcers/

Home About Mayo Clinic Contact Us Mayo Clinic Locations: Arizona Florida Minnesota Mayo Clinic ... Medical Services Peptic Ulcers Peptic Ulcers Treatment Questions and Answers about H. pylori Appointments Clinical Trials ... Medical Services Treatment of Peptic Ulcers at Mayo Clinic (Synonyms: stomach ulcers, duodenal ulcers) Ulcer is a medical term for an open sore, and a peptic ulcer is a sore in the lining of your stomach or small intestine. Left untreated, peptic ulcers can cause internal bleeding (commonly called a bleeding ulcer). Peptic ulcers may even perforate the wall of your stomach or small intestine. Peptic ulcers usually cause pain from stomach acid washing over the open sore. But the pain may decrease or even disappear when bleeding occurs because the blood buffers the acid. About 10 percent of people with bleeding peptic ulcers do not experience pain. Peptic ulcers are common. Five to 10 percent of Americans experience a peptic ulcer at some point in their lives. The good news is that the rate of bacterial infections that can cause some peptic ulcers seems to be dropping in the United States. You should not treat an ulcer on your own, without seeing a doctor. Over-the-counter antacids and acid blockers may relieve the frequent pain, but the relief is always short-lived. With a doctor's help, you can find prompt relief from ulcer pain as well as a lifelong cure from the disease.

77. Peptic Ulcers peptic ulcers. become corroded by stomach acid. peptic ulcers are named according to where they are situated. An ulcer in the stomach http://www.irishhealth.com/?level=4&con=343

78. PHA 4140 - Peptic Ulcer Disease Handout preventing NSAIDinduced gastric ulcers than NSAID-induced duodenal ulcers * Also effective in the treatment of non-NSAID induced peptic ulcers, however, not a http://wiz2.pharm.wayne.edu/module/pud.html

PHA 4140 - Peptic Ulcer Disease Instructor: Peter Dumo, Pharm.D. Lecture Outline 1. Epidemiology 2. Gastric Physiology a) Acid Secretion, Mucosal Protection b) Aggressive Factors c) Defensive Factors 3. Pathogenesis of PUD a) Role of Helicobacter pylori b) Role of NSAIDS c) Role of Corticosteroids d) Other Factors 4. Clinical Presentation a) Signs and Symptoms b) Physical Exam 5. Diagnostic Tests and Procedures 6. Treatment a) Antisceretory/Anti-acid Agents 1) H2-blockers 2) Proton-pump inhibitors 3) Antacids b) Cytoprotectives 1) Misoprostil 2) Sucralfate c) H. pylori Agents d) H. pylori Treatment Regimens e) Prevention and Treatment of NSAID-induced ulcers 7. Cases 1. Epidemiology * About 10% of Americans will develop peptic ulcer disease (PUD) in their lifetime * Currently, men and women are equally afflicted * Duodenal ulcers tend to occur at a younger age than gastric ulcers * Close relationship between PUD and a bacteria called Helicobacter pylori (H. pylori) 2. Gastric Physiology a) Acid Secretion * The human stomach contains about 1 billion parietal cells * These are located in the walls of the midsection of the oxyntic glands * Oxyntic glands are the secretory glands of the gastric mucosa * Oxyntic glands also contin chief, mucous, endocrine, and somatostatin cells

79. The Peptic Ulcer File: Promising New Research Updated regularly over 100 descriptions of the latest treatments for peptic ulcersfrom specialists in gastrointestinal disorders worldwide. http://www.lifestages.com/health/pepticul.html

The Peptic Ulcer File SM C E N T E R F O R C U R R E N T R E S E A R C H Approved by Physicians' Home Page Medinex Seal of Approval WellnessWeb: The Patient's Network HONcode Principles of the Health On the Net Foundation Partners of CareData.com W Peptic Ulcer File . Learn about late-breaking research from world-renowned experts in gastroduodenal ulcer care. Compiled from the National Library of Medicine database at the National Institutes of Health, the Peptic Ulcer File Peptic Ulcer File informs you about studies at such distinguished institutions as the Mayo Clinic, the University of Pennsylvania Division of Gastroenterology, and the Johns Hopkins Medical Center. The Peptic Ulcer File brings you the inside medical story on: Helicobacter pylori Infection Surgery for Peptic Ulcers Drug Treatments for Peptic Ulcers Alternative and Additional Therapies General Studies in Peptic Ulcer Care Access to Free Full-Text Articles from Postgraduate Medicine And Much More . . .

80. Helicobacter Pylori And Peptic Ulcer Disease A peptic ulcer is a sore or hole in the lining of the stomach or duodenum (the first good news is that most ulcers are caused by an infection with http://www.cdc.gov/ulcer

Division of Bacterial and Mycotic Diseases Helicobacter pylori and Peptic Ulcer Disease Menu Good News - A Cure for Ulcers! H. pylori Fact Sheet for Health Care Providers Economic Impact of Ulcers ... Education Materials Order Form Related Contents Foodborne and Diarrheal Diseases Branch DBMD Disease Listing - H. pylori CDC Morbidity and Mortality Weekly Report (MMWR) Ulcer Awareness Week October 6-13, 2003 View details on Ulcer Awareness Week 2003 A peptic ulcer is a sore or hole in the lining of the stomach or duodenum (the first part of the small intestine). People of any age can get an ulcer and women are affected just as often as men. Over 25 million Americans will suffer from an ulcer at some point during their lifetime. The good news is that most ulcers are caused by an infection with the bacterium, Helicobacter pylori , and can be cured in about two weeks with antibiotics.

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