41. Disease Category Listing (35): Pancreatic Cancer Clinical Trials pancreatic cancer. Alabama. Joseph s/Candler Health System, Inc. pancreatic cancer (1). Savannah; St. Joseph s/Candler Health System, Inc. http://www.centerwatch.com/patient/studies/cat35.html

Clinical Trials: Pancreatic Cancer Alabama Birmingham; Research Site A Randomized, Placebo-Controlled, Double-Blind Phase 2 Study of Gemcitabine plus LY293111 Compared to Gemcitabine plus Placebo in Patients with Locally Advanced or Metastatic Pancreatic Cancer California Duarte; City of Hope National Medical Center An Open Label, Randomized, Controlled, Phase III, Multi-centered, Clinical Trial of PN401 with High Dose 5-Fluorouracil (5-FU) versus Gemcitabine for Treatment of Patients with Advanced Pancreatic Cancer Florida Lakeland; Research Site A Randomized, Placebo-Controlled, Double-Blind Phase 2 Study of Gemcitabine plus LY293111 Compared to Gemcitabine plus Placebo in Patients with Locally Advanced or Metastatic Pancreatic Cancer Georgia Savannah; St. Joseph's/Candler Health System, Inc. Pancreatic Cancer (1) Savannah; St. Joseph's/Candler Health System, Inc. Pancreatic Cancer (2) Indiana Indianapolis; Indiana Oncology Hematology Consultants Pancreatic Cancer Research Study. Kentucky Lexington; University of Kentucky Chandler Medical Center Massachusetts Swansea; JM Clinical Trials, Inc.

42. Discovery Health Pancreatic Cancer pancreatic cancer occurs when cells within the pancreas undergo changes that make the cells grow and divide uncontrollably. http://health.discovery.com/diseasesandcond/encyclopedia/3079.html

43. Pancreatic Cancer - Overview, Risk Factors & Symptoms - OncologyChannel.com pancreatic cancer is the fifth leading cause of cancerrelated death, the risk of contracting this cancer increases for a number of reasons. http://www.oncologychannel.com/pancreaticcancer/

Home Search SiteMap Ask the Dr. ... Medical Store advertisement advertisement PANCREATIC CANCER Overview Risk Factors Symptoms Diagnosis ... Prevention CONDITIONS Adrenal Cancer AIDS-Related Lymphoma Anemia Bladder Cancer Brain Cancer Breast Cancer ... Classification of Cancer Colorectal Cancer Cytopenia Endometrial Cancer Esophageal Cancer ... Lymphoma- Hodgkin's Disease Lymphoma- Non-Hodgkin's Ovarian Cancer Pain Pancreatic Cancer Prostate Cancer ... Urethral Cancer RESOURCES Health Quizzes Education Links Videos ... What Is a Gynecologic Oncologist? Oncology Team ABOUT US Healthcommunities.com Pressroom Testimonials The pancreas is an organ of the digestive system. It is located near the stomach and small intestine. It has two major jobs or functions. First, the exocrine pancreas makes enzymes that help in the digestion of food products. Second, the endocrine pancreas produces several hormones that have diverse functions. Cancers of the pancreas can occur in the exocrine pancreas (classic pancreatic adenocarcinomas) or can occur in the endocrine pancreas. This section will discuss exocrine pancreatic carcinoma. Risk Factors The risk of developing cancer of the pancreas is usually low before the age of 40, but the risk subsequently increases sharply, with most people diagnosed between their sixties and eighties. Risk factors for the development of this disease include environmental factors, medical/surgical factors, genetic factors, and occupational exposures.

44. National Cancer Institute - Q&A: The Phase III Gonzalez Protocol Trial Questions and answers from the U.S. National Cancer Institute regarding a clinical trial for pancreatic cancer using an alternative nutritional oriented therapy. http://www.cancer.gov/templates/doc.aspx?viewid=B7014C36-50A1-4464-B28B-7C5DF89E

45. Dartmouth Researchers Advance Fight Against Pancreatic Cancer Two Dartmouth medical studies have produced promising results in the fight against pancreatic cancerone of the most deadly and aggressive forms of cancer http://www.eurekalert.org/pub_releases/2004-05/dms-dra051204.php

Public release date: 15-May-2004 Contact: Andy Nordhoff DMS.Communications@Dartmouth.edu Dartmouth Medical School Dartmouth researchers advance fight against pancreatic cancer New studies show success in reducing tumor growth LEBANON, NH Two Dartmouth medical studies have produced promising results in the fight against pancreatic cancer, one of the most deadly and aggressive forms of cancer, and may lead to the development of new, highly targeted therapies to manage previously untreatable tumors. In two trials targeting some of the most challenging traits of pancreatic tumor cell growth, researchers from Dartmouth Medical School (DMS) and the Norris Cotton Cancer Center (NCCC) at Dartmouth-Hitchcock Medical Center (DHMC) have demonstrated success in slowing and preventing tumor development. The NCCC research team was led by Dr. Murray Korc, a pioneer in early research on growth factor receptors in pancreatic cancer, and chair of the department of medicine at DMS and DHMC. An endocrinologist and cancer biologist, he focuses much of his research on the mechanisms that make pancreatic cancer so resilient and aggressive. Work reported in the May 15 issues of Clinical Cancer Research and Cancer Research addresses the team's latest advances. Pancreatic cancer is characteristic for its ability to spread quickly, while becoming increasingly resistant to traditional chemotherapy. Generally diagnosed in an advanced state, it is frequently inoperable. As a result, it is the fourth leading cause of cancer death in adults in the US, killing more than 30,000 Americans every year, says Korc.

46. Pancreatic Cancer Offers information about pancreatic cancer including causes, symptoms, prevention and treatment. http://www.mamashealth.com/cancer/pancancer.asp

Mamashealth.com Home Cancer Pages Anal Cancer Breast Cancer Breast Cancer Treatment Cancer ... Breast Cancer Journey Links Email Mama What is Pancreatic Cancer? Cancer of the pancreas is abnormal cell growth in the tissue of the pancreas. The pancreas is a small organ (about six inches long) located next to the small intestine, behind the stomach. The majority of pancreatic cancers are adenocarcinomas. Adenocarcinomas are tumors that arise from the exocrine portion of the pancreas. The exocrine portion of the pancrease produces digestive fluids. A small number of pancreatic cancers begin in the endocrine pancreas. The endocrine portion produces hormones (such as insulin). What does the Pancreas Do? The pancreas produces juices and enzymes to help with digesting and absorbing food. The pancreas also produces and releases several hormones, such as insulin, which regulate the way your body stores and processes food. For more information on insulin related conditions, see diabetes Symptoms Someone with pancreatic cancer in the early stages of the disease may have no symptoms. Each individual may not experience all symptoms. The most common symptom is abdominal discomfort. The abdominal discomfort may be worse after eating or when lying down and sometimes can be relieved by sitting up or leaning forward. Other symptoms are: jaundice, nausea, itching, loss of appetite, brown urine, light colored bowel movements, weight loss, or pain in the upper or middle sections of the abdomen.

47. Pancreatic Cancer Blood Test & Gene Studies Show Promise New research may give pancreatic cancer patients a better chance at early detection, firm diagnosis and better treatment options. http://www.eurekalert.org/pub_releases/2004-05/uomh-pcb051904.php

Public release date: 19-May-2004 Contact: Kara Gavin kegavin@umich.edu University of Michigan Health System Protein biomarker, cell-signaling studies may aid detection and treatment NEW ORLEANS Pancreatic cancer kills swiftly and surely, and often goes undiagnosed until it's far too late for doctors to provide the only cure: surgery. But new research being reported here this week may give patients a better chance at early detection, firm diagnosis and, someday, better treatment options for the fourth leading cause of cancer death. Today, researchers from the University of Michigan Comprehensive Cancer Center announced that they have found a protein which allows them to tell pancreatic cancer from normal tissue better than the current "gold standard" blood test used nationwide. They believe this protein, called CEACAM 1, could be used to detect early signs of cancer, especially in those patients at highest risk for the disease. Yesterday, the same team reported new findings about the basic cellular processes that allow pancreatic cancer to develop. The discovery of "crosstalk" between two cell signaling pathways involved in the disease may yield clues as to why pancreatic tumors develop, and perhaps one day lead to innovative ways to stop them. Also today, the U-M researchers reported initial results from gene-based efforts to tell pancreatic cancer from its more common imposter: chronic inflammation of the pancreas, or pancreatitis. By looking at expression levels for three genes in tiny tissue samples removed from patients through a slender needle, they were able to distinguish the two conditions. More research is needed, but the technique could lead to new ways of telling pancreatitis from cancer without the need for surgery.

48. Pancreatic Cancer - Cancer: Health And Medical Information About Cancer Detectio pancreatic cancer (Cancer of the Pancreas). The spread of cancer is called metastasis. Cancer that starts in the pancreas is called pancreatic cancer. http://www.medicinenet.com/pancreatic_cancer/article.htm

document.write(''); MedicineNet Home Cancer Home > Pancreatic Cancer Advanced Search Printer-Friendly Format Add to Favorites Email to a Friend ... Next page Pancreatic Cancer (Cancer of the Pancreas) What is the pancreas? What is cancer? What causes cancer of the pancreas? What are symptoms of cancer of the pancreas? ... What resources are available to cancer patients and families? What is the pancreas? The pancreas is a spongy, tube-shaped organ about 6 inches long. It is located in the back of the abdomen, behind the stomach. The head of the pancreas is on the right side of the abdomen. It is connected to the duodenum, the upper end of the small intestine. The narrow end of the pancreas, called the tail, extends to the left side of the body. The pancreas makes pancreatic juices and hormones, including insulin . Pancreatic juices, also called enzymes, help digest food in the small intestine. Insulin controls the amount of sugar in the blood. Both enzymes and hormones are needed to keep the body working right. As pancreatic juices are made, they flow into the main pancreatic duct. This duct joins the common bile duct, which connects the pancreas to the liver and the gallbladder. The common bile duct, which carries bile (a fluid that helps digest fat), connects to the small intestine near the stomach.

49. The American Gastroenterological Association - Links General related links including those of pancreatic cancer offered by the American Gastroenterological Association. http://www.gastro.org/links/

Links World Wide Web Sites of Interest to Gastroenterologists American Association for the Study of Liver Diseases American Board of Internal Medicine Institute for Clinical Evaluation American Board of Physician Nutrition Specialists (ABPNS) ... Federal Trade Commission's "Operation Cure-All" - Tips off Consumers and Businesses about Fraudulent Health Claims on the Internet GastroHep Gastroenterology Research Group (GRG) G.I. Fellowship Training Program at the University of Cincinnati International Association of Surgeons and Gastroenterologitsts ... JAMWA - Women's Health Link Library Liver Tissue Procurement and Distribution System (LTPADS) LiverTumor.org Local Medicare Review Policy - for all Medicare Carriers Medical University of South Carolina's Digestive Disease Center MEDLINEplus a service of the U.S. Library of Medicine and the National Institutes of Health. National Cancer Institute National Institute of Diabetes, Digestive and Kidney Diseases

50. Mice Mimic Pancreatic Cancer: New Animal Model Could Help Catch Hidden Lethal Tu Mice mimic pancreatic cancer. SPL. Researchers have created the first mice that mimic pancreatic cancer, a common but oftenignored killer. http://www.nature.com/nsu/031208/031208-12.html

updated at midnight GMT search nature science update advanced search Mice mimic pancreatic cancer New animal model could help catch hidden lethal tumours. 11 December 2003 HELEN PEARSON Cancer cells (green) spread easily from the pancreas (red) to the liver (pink). Researchers have created the first mice that mimic pancreatic cancer, a common but often-ignored killer. The animals should help to improve diagnosis and to develop drugs for the disease. Around 30,000 people in the United States and 60,000 in Europe are diagnosed each year with cancer of the pancreas, a small organ that helps to digest and metabolize food. Because tumours are often detected after having spread, the cancer is one of the most virulent. Most patients die within months. Two research groups have now created mice that grow pancreatic tumours, by genetically engineering key cancer-causing genes. David Tuveson of the University of Pennsylvania, Philadelphia, and his colleagues did one study ; Ron DePinho at the Dana-Farber Cancer Institute in Boston and his team the other The teams hope to identify telltale blood molecules that warn of a burgeoning but hidden tumour. Tuveson's team has already found a group of such proteins circulating in cancerous mice, but not healthy ones.

51. ACOR Mailing Lists Archives Join an ongoing moderated conversation with patients, family and caregivers through email. http://listserv.acor.org/archives/pancreas-onc.html

Search ACOR Find a mailing list Search a list's archives Search the dictionary Search Cancer News Archives of PANCREAS-ONC@LISTSERV.ACOR.ORG PANCREAS-ONC: The Pancreatic Cancer Support Group Note: You must be subscribed to this list in order to view the archives From this page you can: Search the archives Post to the list Join or leave the list (or change settings) Manage the list (list owners only) or Browse PANCREAS-ONC in: June 2004 May 2004 April 2004 March 2004 ... Site Map ACOR.org delivered individual emails across the globe last week. ACOR and ACOR.org are registered trademarks of the Association of Online Cancer Resources, Inc.

52. M. D. Anderson Cancer Center - Pancreatic Tumor Study Group The University of Texas MD Anderson Cancer Center has revolutionized pancreatic cancer treatment by integrating medical disciplines together for better patient http://www.mdanderson.org/departments/pancreatic/

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53. Pancreatic Cancer Purple Ribbon Room Provides a message board, chat, support and information for patients and caregivers. MSN signin required. http://groups.msn.com/PancreaticCancerPurpleRibbonRoom

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54. Pancreatic Cancer: Online Reference For Health Concerns pancreatic cancer overview, causes, conventional and adjuvant treatment information. pancreatic cancer Updated 04/06/2004. http://www.lef.org/protocols/prtcl-113.shtml

var WebSiteBaseURL = "http://www.lef.org/protocols/prtcl-113.shtml" translation by SYSTRAN MEMBERSHIP PRODUCTS MAGAZINE ... CHECKOUT Health Concerns Selector Select Health Concern Acetaminophen (tylenol) Poi... Acne Adrenal Disease Age-associated Mental Impai... Alcohol Induced Hangover: P... Allergies Alzheimer's Disease Amnesia Amyotrophic Lateral Scleros... Anemia-thrombocytopenia-leu... Anesthesia And Surgical Pre... Anxiety And Stress Arrhythmia (cardiac) Arthritis Asthma Atherosclerosis Attention Deficit Disorder ... Autism Autoimmune Diseases Avoiding Vitamin - A Toxicity Bacterial Infections Balding Bell's Palsy Bladder Conditions Breast Cancer Bursitis Cancer - Overview Cancer Adjuvant Treatment Cancer Chemotherapy Cancer Clinics Cancer Gene Therapy Cancer Prevention Cancer Radiation Therapy Cancer Supplements Cancer Surgery Cancer Treatment: The Criti... Cancer Vaccines Candida (fungal, Yeast) Inf... Cardiovascular Disease: Co... Cardiovascular Disease: Ove... Carpal Tunnel Syndrome Catabolic Wasting Cataract Cerebral Vascular Disease Cervical Dysplasia Cholesterol Reduction Chronic Fatigue Syndrome (cfs) Cirrhosis Colitis (ulcerative) Colorectal Cancer Common Cold Congestive Heart Failure An...

55. Pancreatic Cancer Online Resources - Make A Difference! A collection of online resources offered by the Decker Fund. http://deckerfund.tripod.com/links.html

var cm_role = "live" var cm_host = "tripod.lycos.com" var cm_taxid = "/memberembedded" Check out the NEW Hotbot Tell me when this page is updated Note: Ads at the top of pages are embedded by Tripod and do not generate revenue for this site. Pancreatic Cancer Online Resources This site has not been created, approved, or supported by any medical professional or medical organization. However, every effort has been made to assure that information given here is reliable. Nearly all of it has been obtained from reputable online sources (such as the National Cancer Institute or the American Cancer Society). Nothing contained on this page or in the pages referenced herein is intended to replace sound medical advice from the professionals of your choice. You should use the information gathered as a knowledge-base to enable you to participate intelligently and productively in your care. Do not use anything you find here as a substitute for professional guidance. We appreciate your visit. Please take a gift with you. Would you like to let others know about this website? Then, please click below (it would be helpful if you also signed up for free ezines, too). Thank you.

56. Pancreatic Cancer Alliance Home Offers summaries of news stories, patient support information, statistics, research advocacy and links to resources. http://www.pancreaticalliance.org

Page updated May 26 News updated June 1 Home Research corner Recent news stories Internet ... About us Mission The Pancreatic Cancer Alliance exists to support the efforts of the medical and research communities as well as patients and their loved ones in the battle against pancreatic cancer. Goals To raise money for research To help educate patients and medical professionals To raise public awareness of pancreatic cancer Pancreatic Cancer Alliance It's time to fight back Have you or a loved one been diagnosed with pancreatic cancer? You are not alone in this fight. The Pancreatic NCI spends just $787 for each pancreatic cancer death, but spends $9,732 for each death from prostate cancer, which kills fewer people. Cancer Alliance exists to support you in your fight against pancreatic cancer. We are a local organization in Central Massachusetts of patients and families affected by pancreatic cancer. On this web site, you'll find links to resources available on the Internet, information on research being undertaken at the University of Massachusetts in Worcester, links to news stories about the struggle as well as information on how you can support research to bring the kinds of advances needed to conquer this underfunded disease.

57. Pancreatic Cancer: General Information About pancreatic cancer. pancreatic cancer is a disease Stages of pancreatic cancer. Tests and procedures to stage http://www.acor.org/cnet/62957.html

Search ACOR Find a mailing list Search a list archives Search the dictionary Search CancerNet Search Cancerguide Pancreatic Cancer Document Last Modified:03/19/2004 General Information About Pancreatic Cancer Stages of Pancreatic Cancer Recurrent Pancreatic Cancer Treatment Option Overview ... About PDQ Key Points Pancreatic cancer is a disease in which malignant (cancer) cells form in the tissues of the pancreas. Smoking and health history can affect the risk of developing pancreatic cancer. Possible signs of pancreatic cancer include jaundice, pain, and weight loss. Pancreatic cancer is difficult to detect (find) and diagnose early. ... Patients with pancreatic cancer have special nutritional needs. General Information About Pancreatic Cancer Pancreatic cancer is a disease in which malignant (cancer) cells form in the tissues of the pancreas. The pancreas is a gland about 6 inches long that is shaped like a thin pear lying on its side. The wider end of the pancreas is called the head, the middle section is called the body, and the narrow end is called the tail. The pancreas lies behind the stomach and in front of the spine.

58. Pancreas (Pancreatic) Cancer pancreatic cancer is the fifth leading cause of cancerrelated mortality in the United States, On a stage for stage basis, cancer of the pancreas is met with http://www.cancersupportivecare.com/pancreas.html

Fifth Dimension Table of Contents Cancer of the Pancreas Andrew H. Ko, M.D. Types How it spreads What Causes It Staging and treatment ... Important questions to ask your doctor Pancreatic cancer is the fifth leading cause of cancer-related mortality in the United States, with an estimated 30,300 deaths attributable to this disease in 2002. In fact, the annual mortality rate almost approximates the annual incidence rate, which reflects the generally short survival time associated with pancreatic cancer, most often less than one year. On a stage for stage basis, cancer of the pancreas is met with the shortest median survival time out of all cancer types. Types Back to the Table of Contents How it spreads Back to the Table of Contents Cancer cells may spread by direct extension from the pancreas to adjacent structures, such as the bile duct, duodenum (small intestine), spleen, colon, adrenal gland, kidney, or vertebra. Cancer cells may also spread to regional lymph nodes. Most common sites of distant metastatic spread include the liver and the lungs (via the bloodstream) and the peritoneum (abdominal cavity). What causes it Back to the Table of Contents Advancing age is the strongest risk factor for pancreatic cancer, with the vast majority of cases occurring after the age of 60 years. There is also a clear association between cigarette smoking and pancreatic cancer; however, the roles of diet, alcohol, and coffee have not been substantiated and should not be considered proven risk factors.

59. Website Memorial site for a gentleman stricken with pancreatic cancer. http://www.peterjbrignola.homestead.com/website.html

In Memory of Peter J. Brignola I armed myself with all of the information I could, when we found out my dad had Pancreatic Cancer. I found that the prognosis is extremely grave. Although there is research being done in this area, detection is extremely difficult. Pancreatic Cancer is the fourth leading cause of cancer death in America. By the time most people experience symptoms, the cancer has spread to other organs. Approximately, 28,300 Americans will be diagnosed with Pancreatic Cancer this year. Only 19% of them will survive one year after diagnosis. I have become a volunteer for the American Cancer Society. They dedicate more money to cancer research than any other private, non-for-profit, non-governmental funder of cancer research in the United States. I ask that you open your hearts, and make a donation to the American Cancer Society, In Memory of Peter J. Brignola. We can no longer stay silent about this very silent disease. By simply making a donation, we can offer Pancreatic Cancer patients in the future, more treatment options, raise awareness, and promote early detection. Make a difference today, and send a donation to: The American Cancer Society ATTENTION: Margie Cleerdin 3407 NW 9 Avenue, Suite 100

60. Treating Hepatobiliary Pancreatic Cancer Treating Hepatobiliary pancreatic cancer We are one of the top centers in the US for hepatobiliary pancreatic surgery. Only 20 years http://www.siteman.wustl.edu/patient/specialized_cc/gastro_treatment2.shtml

Care Centers Breast Cancers Gastrointestinal Cancers Gynecological Cancers Head and Neck Cancers Leukemia and Lymphoma Musculoskeletal Cancers Nervous System Cancers Pediatric Cancers Skin Cancers and Melanoma Thoracic Cancers Thyroid Cancers Urological Cancers Treating Hepatobiliary Pancreatic Cancer We are one of the top centers in the U.S. for hepatobiliary pancreatic surgery. Only 20 years ago, major surgery for cancer of the liver, pancreas or biliary tract was very risky. Patients faced high-operative morbidity and a mortality rate at many hospitals that reached 20 percent. But today, Siteman Cancer Center surgeons have managed to attain a safety record that once would have been unattainable. For example, the major operation for pancreatic cancer patients is the intricate Whipple procedure, which involves removal of the pancreas, a portion of the stomach, the duodenum, common bile duct and gallbladder. Surgeons in the hepatobiliary pancreatic surgery section at Barnes-Jewish Hospital performed 55 Whipple procedures in 1998 and 75 in 1999. And in the past 125 Whipples, there has not been a single death. The mortality rate for the 60 liver resections they do each year is also very low — just 1 percent. The success of the hepatobiliary pancreatic section — a subspecialty within gastrointestinal surgery — has made the Siteman Cancer Center one of the top centers in the United States for hepatobiliary pancreatic procedures. Studies have shown that patients benefit from treatment performed in this kind of specialized, high-volume unit, which produces better outcomes for patients, with lower morbidity and lower mortality.

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