81. Osteoarthritis Info Page - The Little Surgery An information leaflet about osteoarthritis. A patient information leaflet, from The Little Surgery, Stamford, UK osteoarthritis. http://web.ukonline.co.uk/ruth.livingstone/little/osteo.htm

A patient information leaflet, from The Little Surgery, Stamford, UK Osteoarthritis What is osteoarthritis? What causes osteoarthritis? Who gets it? What are the symptoms? ... Special equipment and aids. What is osteoarthritis? Osteoarthritis is caused by "wear and tear" to the surface of your joints. Joint surfaces are usually smooth, but with osteoarthritis they become roughened and thinner. Joint movements then become painful, and joints can become inflamed. What causes osteoarthritis? We are not sure why some people develop osteoarthritis, and other people don't. Some things will increase your risk of developing arthritis, being overweight a previous injury to a joint, eg. a fracture a heavy occupation overuse due to sport a congenital abnormality in a joint a joint already affected by another form of arthritis Who gets it? Osteoarthritis is very common, and most of us will develop arthritis in one or more of our joints as we grow older. It is very rare under the age of 40. Usually, osteoarthritis involves joints which have suffered a lot of stress in life, such as our knees or hips. The lower back and the neck bones are often affected. The bottom of the thumbs, and the end of the fingers are common sites, particularly in women. What are the symptoms?

82. Arthritis Information Center: Osteoarthritis Information on osteoarthritis including definition, treatments, medications and resources. Prescription Drugs). osteoarthritis (OA) Most http://www.healthsquare.com/osteoarthritis.htm

Privacy About Linking Advertising Advertisement Home Arthritis Encyclopedia of Medicine Guide to Prescription Drugs Advertisement Advertisement HEALTH INFORMATION CENTER AIDS / HIV Allergies ... Pharmacies Advertisement Arthritis (From the PDR Family Guide to Prescription Drugs) Osteoarthritis (OA) Most people will suffer from some form of OA as they grow older, and the joints naturally age through wear and tear. The most notable symptom, a dull aching feeling in the joints, usually appears toward the end of the day. The joints most commonly affected are in the hands, knees, fingers, spine, hips, neck, and feet. OA is a progressive disease and is not usually reversible. However, medication can relieve the symptoms. Treatment for OA usually starts with a mild drug such as acetaminophen (Tylenol) or aspirin taken every four to six hours as needed. As the disease progresses, symptoms become more severe, and a COX-2 inhibitor or a traditional NSAID may be substituted. The available COX-2 inhibitors are celecoxib (Celebrex) and rofecoxib (Vioxx). Likely choices among the NSAIDs include ibuprofen (Motrin), indomethacin (Indocin), meloxicam (Mobic), or naproxen (Naprosyn). If OA pain becomes especially severe, a doctor will sometimes prescribe a short course of narcotic pain relievers such as Tylenol with Codeine. When joints become inflamed, injections of corticosteroids such as cortisone or prednisone can be effective.

83. Osteoarthritis From Veritas Medicine Clinical trial listings for osteoarthritis. Perform a personalized search to find ongoing trials that match your needs. http://www.veritasmedicine.com/osteoarthritis/

Jump to another condition or disease... Allergic Disorders Alzheimer's Disease Anxiety Disorders Asthma Bipolar Disorder Bladder Disorders Brain Tumors Breast Cancer Cholesterol Disorders Chronic Pain Colorectal Cancer Constipation and Pain (OBD) COPD Coronary Heart Disease Crohn's Disease Dementia Disorders Depression Diabetes Endometriosis Epilepsy Fertility Treatments Foot Disorders Hepatitis C Herpes High Blood Pressure HIV Hodgkin's Disease Inflammatory Bowel Disease Leukemia Leukemia - ALL Leukemia - AML Leukemia - CLL Leukemia - CML Lung Cancer Lupus Lymphoma Melanoma Menopause Migraine Multiple Sclerosis Non-Hodgkin's Lymphoma Obesity Oral Disorders Osteoarthritis Osteoporosis Ovarian Cancer Pancreatic Cancer Parkinson Disease Prostate Cancer Prostate Disorders Psoriasis Recurrent Pregnancy Loss Renal Cell Carcinoma Reproductive Conditions Rheumatoid Arthritis Schizophrenia Sexual Dysfunction Skin Disorders Sleep Disorders Stroke Ulcerative Colitis Urinary Incontinence Uterine Fibroids Vascular Disorders Osteoarthritis Home Find Clinical Trials About Clinical Trials Personalized Trial Notification ... Advanced Osteoarthritis Veritas Medicine's online resource for Osteoarthritis allows you to search for clinical trials, receive free email updates, and learn about the clinical research process.

84. BBC News | HEALTH | Osteoarthritis Gene Breakthrough Scientists have identified genetic factors which may increase the risk of developing osteoarthritis. http://news.bbc.co.uk/1/hi/health/1898557.stm

CATEGORIES TV RADIO COMMUNICATE ... INDEX SEARCH You are in: Health Front Page World UK ... AudioVideo SERVICES Daily E-mail News Ticker Mobiles/PDAs Feedback ... Low Graphics Monday, 1 April, 2002, 23:01 GMT 00:01 UK Osteoarthritis gene breakthrough The scientists looked at osteoarthritis of the hand Scientists have identified genetic factors which may increase the risk of developing osteoarthritis. The breakthrough brings closer the prospect of effective treatments for the crippling disease. The US study, which looked at osteoarthritis in the hand, found eight areas of the human genome indicated an inherited risk for the disease. The discovery could provide information for doctors looking for new ways of diagnosing and treating osteoarthritis. Identifying so-called chromosomal regions on the genome, each which contain 50 to 100 genes, allows scientists to narrow down their hunt for the specific genes responsible for an individual condition. If we do manage to identify the genes that provide a disease risk in OA, it will tell us a great deal about how the disease develops Dr Madeleine Devey, Arthritis Research Campaign

85. BBC NEWS | Health | Gene Hope For Osteoarthritis Scientists hope they will soon be able to stop osteoarthritis and prevent painful joint replacements. Gene hope for osteoarthritis. http://news.bbc.co.uk/1/hi/health/2665609.stm

Home TV Radio Talk ... Programmes Last Updated: Saturday, 22 March, 2003, 00:22 GMT Email this to a friend Printable version Gene hope for osteoarthritis Scientists are optimistic about treatment Scientists hope they could soon be able to delay the progression of osteoarthritis and prevent painful joint replacements. Researchers at the University of Manchester's School of Biological Science hope their work will lead to an effective new treatment for the millions in the UK with osteoarthritis. Dr Gillian Wallis, a senior lecturer in medicine who is helping lead the research programme, said they hoped to develop a type of gene therapy. "We're very optimistic. We've been working towards this for about 10 years now, and we're at the point where we can talk about developing treatment. Target "We're confident that we will find effective target genes, which we then plan to introduce into joints using carrier viruses. "Obviously we are still very much at the research stage, but if all our laboratory experiments work out then we hope to translate the results directly into clinical practice." She said they hoped this would mean fewer painful operations for those with the condition.

86. Frequently Asked Questions On Knees, Hips And Backs The Florida Knee and Orthopedic Center. osteoarthritis of the knee and hip, knee and hip replacement. http://www.fla-ortho.com/frames/faqs/faqs.htm

87. MayoClinic.com - Osteoarthritis osteoarthritis, a wearand-tear condition that develops as you age, is the most common form of arthritis. osteoarthritis By Mayo Clinic staff Overview http://www.mayoclinic.com/invoke.cfm?id=DS00019

88. Naturalhealthlink.com Detailed information on osteoarthritis, arthritis, rheumatoid arthritis, symptoms, treatments and related nutritional and herbal supplements. http://www.naturalhealthlink.com/ReferenceLibrary/healthnotes.asp?ArticleID=109&

89. Osteoarthritis Prevalence of osteoarthritis osteoarthritis (OA) is the most prevalent arthritic disorder, 3 affecting approximately 16 million people in this country, and is http://www.familypractice.com/references/ABFPGuides/Osteoarthritis/arthritis.htm

OSTEOARTHRITIS Contributors Overview The History The Physical Examination ... Download PDF Version Contributors Major contributors to this reference guide were: Elise M. Coletta, M.D. Chief of Gerontology Memorial Hospital of Rhode Island Pawtucket, Rhode Island Assistant Professor of Family Medicine Brown University School of Medicine Providence, Rhode Island Edward V. Lally, M.D. Director of Rheumatology Roger Williams Medical Center Providence, Rhode Island Associate Professor of Medicine Brown University School of Medicine Providence, Rhode Island Major contributors to the first edition were: John D. Clough, M.D. George Shacklett, M.D. T. Paul Wilder, M.D. The major contributor to the second edition was: J.R. Olson, M.D. Major contributors to the third and fourth editions were: James R. Buechler, M.D. Doyt L. Conn, M.D.

90. Bmj.com Collected Resources : Osteoarthritis osteoarthritis. Citations 110 of 25 total displayed. Most recent content (10 Apr 2004) Primary care Corticosteroid injections for http://bmj.bmjjournals.com/cgi/collection/Osteoarthritis

Home Help Search/Archive Feedback Collected Resources Osteoarthritis Citations 1-10 of 25 total displayed. Most recent content (10 Apr 2004): Primary care Corticosteroid injections for osteoarthritis of the knee: meta-analysis Bruce Arroll and Felicity Goodyear-Smith BMJ 2004;328:869, doi:10.1136/bmj.38039.573970.7C [Abstract] [Abridged text] [Abridged PDF] [Full text] ... [PDF] Past content (since May 1999): Primary care Corticosteroid injections for osteoarthritis of the knee: meta-analysis Bruce Arroll and Felicity Goodyear-Smith BMJ, doi:10.1136/bmj.38039.573970.7C (published 23 March 2004) [Abstract] [PDF] BMJ USA: COMMENTARY An orthopedist responds Stephen J Franzino BMJ 2003;327:E251, doi:10.1136/bmjusa.03090004 [Full text] [PDF] News roundup High heels ruled out as risk factor in osteoarthritis of the knee Roger Dobson BMJ 2003;327:768 , doi:10.1136/bmj.327.7418.768-b [Abridged text] [Abridged PDF] [Full text] Papers Commentary: An orthopedist responds Stephen J Franzino BMJ, doi:10.1136/bmjusa.03090004 (published 30 September 2003)

91. Spine-health.com Provides indepth information written by doctors about osteoarthritis and back pain, its causes, diagnosis and treatment options. http://www.spine-health.com/search/osteoarth01.html

92. Osteoarthritis osteoarthritis (OA) is a chronic disease of the joints, especially the weightbearing joints that develops when the linings of joints degenerate, leading to http://www.vitacost.com/science/hn/Concern/Osteoarthritis.htm

My account View cart / Checkout Email us Enter keyword or item number New Products Products Categories Brands ... Health Concerns Get Our Full Color Catalog delivered to your door. FREE! A convenient way to shop and get the health information you want! A weekly nutritional advice newsletter from our staff of medical doctors. eNewsletter Archives Your Right to Privacy Customer Service Ordering Methods Shipping Information 5 Star Guarantee Download Order Forms Still have questions? Talk to one of our friendly customer service representatives using Live Chat Science Health Notes Encyclopedia Product Reviews Age Related Macular Degeneration News News Room eNewsletter Archives Vitacost News Releases Additional Resources Physician's Reference Guide and Discount Program drkoop.com health-fitness-tips.com drdrew.com ... Join our affiliate program! Index: All Healthnotes Indexes Foodnotes Health Centers Health Concerns Herbal Remedies Homeopathy Recipes Recipes by Course Recipes by Main Ingredient Recipes International Recipes Seasonal Safetychecker Special Diets Special Recipes Vitamin Guide Weight Control Health Center Search: Osteoarthritis Also indexed as: Arthritis (Osteo), Degenerative Arthritis, Degenerative Joint Disease (DJD)

93. All About Arthritis osteoarthritis Know the risk factors, symptoms, medications and other available treatments http://www.allaboutarthritis.com/arthritis.cfm/about/167

94. Osteoarthritis osteoarthritis,. Print this article, degenerative joint disease affecting synovial joints. Although the term osteoarthrosis may be http://www.amershamhealth.com/medcyclopaedia/medical/Volume III 1/OSTEOARTHRITIS

Amershamhealth.com Search for: Type a word or a phrase. All forms of the word are searchable. Browse entry words starting with: A B C D ... Other characters Osteoarthritis, degenerative joint disease affecting synovial joints . Although the term osteoarthrosis may be more appropriate because in this condition inflammatory changes are not pronounced, the term osteoarthritis is more widely accepted. In osteoarthritis, cartilage and bone are the primary sites of abnormality, with only mild alterations occurring in the synovial membrane. Typically radiographs reveal loss of joint space eburnation , cyst formation and osteophytosis . Complications of this disorder include subluxation joint malalignment , fibrous ankylosis and intra-articular osseous and cartilaginous bodies. Two special varieties of osteoarthritis (generalized osteoarthritis and inflammatory [erosive] osteoarthritis) have also been described but may not be discrete entities. Joint degeneration may result either from an abnormal concentration of force across a joint with normal articular cartilage matrix or from a normal concentration of force across an abnormal joint. Among the causes of osteoarthritis are inherited factors, obesity, inflammation, trauma, mechanical factors, nutritional and metabolic status, osteoporosis and preexisting joint disease or deformity. In one way or another, these factors create a situation in which the joints can no longer resist the physical forces.

95. Osteoarthritis And Exercise The Health Gazette. Karl Hempel, MD. osteoarthritis and Exercise. As joints. Does running contribute to the development of osteoarthritis? http://www.tfn.net/healthgazette/osteo.html

The Health Gazette Karl Hempel, M.D. Osteoarthritis and Exercise As a long-time runner, I have been concerned about the effects of running on my joints. Does running contribute to the development of osteoarthritis? For years, I have done frequent literature searches to see if there are any new studies that might help provide an answer to this question. Osteoarthritis refers to a degeneration of the cartilage that cushions the joints. Over a period of time, the cartilage can be worn down to the point that the bones are actually rubbing against each other. This results in pain with movement of the joints. Recently, there was a review of the literature concerning osteoarthritis and exercise. It was in the Rheumatic Disease Clinics of North America . In this column I will discuss the conclusions of the review. Most of the literature seems to suggest that osteoarthritis is more related to age and heredity than it is to exercise. This was a welcome relief, but there are a few catches. The chance of getting osteoarthritis is significantly increased in people who have a pre-existing injury to the knee, hip or ankle joint and run or jog on a regular basis. This does not refer to a running injury, but more to a serious injury that causes damage to the cartilage or produces a torn ligament. Another factor that predisposes one to osteoarthritis is an anatomical abnormality of the weight-bearing joints. Examples of anatomical abnormalities would be knock-knees, bowlegs or leg-length discrepancy. This evidently puts much stress on the joints while running and can cause joint damage.

96. Arthritis Insight-Osteoarthritis osteoarthritis. Our osteoarthritis survey showed that it is the most common type of arthritis for Arthritis Insight Members. And http://arthritisinsight.com/medical/disease/oa/

In this section: Osteoarthritis-Index Disease Description Possible Causes of OA Viscosupplementation Surgical Options Links for more Information Back to Disease Index Current Discussion Archives Survey Disease Index ... Disease Index Osteoarthritis Osteoarthritis Our Osteoarthritis survey showed that it is the most common type of arthritis for Arthritis Insight Members. And that is true for the rest of America also. Osteoarthritis is the most common form of arthritis, affecting an estimated 20.7 million Americans. Almost every person over the age of 75 has OA in at least one joint. However the average age of our respondents with OA was 35-45. Disease Description Symptoms, diagnosis, treatment, and more. Is it worth all the hype? Surgical Options for OA When nothing else works, sometimes surgery is the answer. Possible Causes of OA There are many factors that lead to the development of osteoarthritis. Viscosupplementation One of the newer treatments for osteoarthritis of the knee is viscosupplementation. Does it work? Links to more information Arthritis Insight isn't the only place on the web to learn about OA. Check out these other sites.

97. Osteoarthritis, UPMC | University Of Pittsburgh Medical Center, Pittsburgh, PA, Diagnosis, treatment, and research information on osteoarthritis from the health care experts from the University of Pittsburgh Medical Center (UPMC). http://arthritis.upmc.com/Osteoarthritis/

Home Osteoarthritis Osteoarthritis is a breakdown of cartilage in the joints and the subsequent growth of bone spurs that become inflamed. Read more Overview Diagnosis Treatment Options ... Contact UPMC Supplemental content provided by HealthGate Data Corp Terms and Conditions

98. Osteoarthritis - Information On Symptoms And Treatment BUPA health information factsheet osteoarthritis is the most common type of arthritis, its main symptoms are pain, stiffness and swelling of the joints. http://hcd2.bupa.co.uk/fact_sheets/html/osteoarthritis.html

search home services health information ... BUPA Products and services Health insurance Financial protection Hospitals Care homes ... International cover Visitor interest areas Individuals Business Intermediaries Health professionals ... BUPA members Facilities finder Find local health and fitness facilities World of BUPA BUPA services around the world at bupa.com health information ABC of health Osteoarthritis Published by BUPA's Health Information Team January, 2003 Download this factsheet The word "arthritis" means inflammation of the joints, and refers to a group of more than 200 diseases of the joints, which affect more than 8 million people in the UK. Osteoarthritis is the most common type of arthritis, affecting around a million people. It is rare in people under 40 but becomes more common with age – most people with the condition are over 65. Symptoms The main symptoms of osteoarthritis are pain, stiffness and swelling of the joints. The joint may have restricted movement, and there may be tenderness or deformity. The joint may also crack or creak (called crepitation). When the joint becomes severely damaged, it may become misshapen, with bony swellings, and unstable. This puts stress on the ligaments and tissues surrounding the joints, and can lead to deformity.

99. Postgraduate Medicine: Improving Outcomes In Osteoarthritis Improving outcomes in osteoarthritis. Preview Most physicians are familiar with the frustration that can accompany treatment of osteoarthritis. http://www.postgradmed.com/issues/1999/05_15_99/cooper.htm

Improving outcomes in osteoarthritis How to help patients stay a step ahead of the pain Sheldon M. Cooper, MD VOL 105 / NO 6 / MAY 15, 1999 / POSTGRADUATE MEDICINE CME learning objectives To understand the risk factors for osteoarthritis To recognize clinical signs and symptoms of osteoarthritis To become familiar with nonpharmacologic and pharmacologic management of osteoarthritis This page is best viewed with a browser that supports tables Preview : Most physicians are familiar with the frustration that can accompany treatment of osteoarthritis. Pain management and slowing of disease progression depend, in part, on how involved patients become in their own treatment program. Education, modification of activities, weight reduction, and muscle strengthening are critical components of therapy. Dr Cooper reviews the conventional approaches to this common disabling disease and offers insight into new, promising therapies. O ver the past 20 years, understanding of the disease process known as osteoarthritis has grown substantially. Osteoarthritis is not a single disease entity. Rather, it is a group of overlapping diseases characterized by damage to and focal loss of cartilage as well as hypertrophic changes (osteophytes) in adjacent subchondral bone (1). Although the process of osteoarthritis may begin at an early age, the incidence of symptomatic disease rises sharply after age 50. The disease is more common in women than in men, affects about 16 million people in the United States, and is increasing in prevalence as the elderly population increases. Symptomatic osteoarthritis, particularly of the knee and hip, is the most common cause of musculoskeletal disability in the elderly. Knee osteoarthritis accounts for most of the total knee replacements performed annually at a cost of more than $4 billion (2).

100. Postgraduate Medicine: RHEUMATIC DISEASES: Getting Control Of Osteoarthritis Pai Getting control of osteoarthritis pain. An update on treatment options. Qaiser Rehman, MD; Nancy E. Lane, MD. Development of osteoarthritis. http://www.postgradmed.com/issues/1999/10_01_99/lane.htm

Getting control of osteoarthritis pain An update on treatment options Qaiser Rehman, MD; Nancy E. Lane, MD VOL 106 / NO 4 / OCTOBER 1, 1999 / POSTGRADUATE MEDICINE CME learning objectives To understand the interaction of factors leading to onset and progression of osteoarthritis To recognize clinical findings that are diagnostic of osteoarthritis To learn the latest pharmacologic, physical, and surgical interventions available to manage osteoarthritis This page is best viewed with a browser that supports tables This is the fourth of four articles on rheumatic diseases Preview : Ironically, patients with osteoarthritis are often advised to do some walking or low-impact exercises to improve conditioning and reduce their weight. However, since pain after activity is the principal symptom of osteoarthritis, using the affected joint may be one of the last things a patient with hip or knee osteoarthritis wants to do. In this article, the authors summarize methods to manage the discomfort of osteoarthritis so patients can continue the most active lifestyle possible. Rehman Q, Lane NE. Getting control of osteoarthritis pain: an update on treatment options. Postgrad Med 1999;106(4):127-34

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