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         Ollier Disease:     more detail
  1. Molecular Profiling of Solitary and Ollier Disease-related Central Chondrosarcomas: An Investigation of DNA Aberrations, mRNA and Protein Expression by Leida B. Rozeman, 2005
  2. Allergy: The Facts (Oxford Medical Publications) by Robert J. Davies, Susan Ollier, 1989-05-18

81. Blackwell Synergy - Cookie Absent
Chondrosarcoma of bone complicating ollier s disease Report of a favourable response to radiotherapy. Bone sarcomas associated with ollier s disease.
http://www.blackwell-synergy.com/links/doi/10.1046/j.1440-1673.2003.01187.x/full
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82. Chondrosarcoma, Secondary To Enchondroma
Site The most common precursor is multiple enchondroma or ollier s disease. This phenomenon is rare in solitary enchondroma or synovial chondromatosis.
http://imc.gsm.com/demos/mskdemo/mspath/enneking/sect14/secencho.html
About Table of Contents Malignant Lesions of Bone Help
Chondrosarcoma, Secondary to Enchondroma
Definition Demographics Clinical Presentation Natural History ... References
Definition
Chondrosarcoma secondary to enchondroma is a primary neoplasm of cartilaginous histogenesis arising from a pre-existing benign enchondroma.
Demographics
Age: 30 - 50 Site: The most common precursor is multiple enchondroma or Ollier's disease. This phenomenon is rare in solitary enchondroma or synovial chondromatosis.
Clinical Presentation
The patient presents with pain at the site of a previously-painless enchondroma.
Natural History
Slow, displacing growth is characteristic of this tumor with very late transition to a high-grade lesion and risk of metastasis. The survival rate is excellent with adequate treatment prior to transition.
Radiographic Features
On radiograph, there is an expanding, radiolucent zone surrounding a calcified enchondroma with endosteal scalloping and periosteal, cortical thickening. [X-Ray] This radiograph shows the original enchondroma at first presentation. The patient was asymptomatic at this time. [X-Ray] This radiograph was made fourteen years later when the patient presented with a secondary chondrosarcoma.

83. Self-evaluation 19 - Question 1 Review
B) ollier s disease 10 percent incidence of transformation CORRECT! The incidence of malignant transformation in solitary enchondroma
http://imc.gsm.com/demos/mskdemo/mspath/enneking/sect14/exam/se191b.html
Self-evaluation 19
Question 1 - Single Best Answer Which of the following couplets concerning the malignant transformation of an enchondroma to chondrosarcoma is appropriate? B) Ollier's disease -10 percent incidence of transformation
CORRECT!

84. AAOS On-Line Service - Scientific Program Ollier's Disease: Correction Of Angula
American Academy of Orthopaedic Surgeons 1994 Annual Meeting Scientific Program. ollier s disease Correction of Angular Deformities and Limb Lengthening.
http://www.aaos.org/wordhtml/anmeet94/sciprog/224.htm
American Academy of Orthopaedic Surgeons
1994 Annual Meeting - Scientific Program
Ollier's Disease: Correction of Angular Deformities and Limb Lengthening
Paper No. 224 FRIDAY, FEBRUARY 25, 1994
3:30-5:30 PM Location: CONVENTION CENTER ROOMS 58-60 Maurizio A. Catagni, MD , Lecco, ITALY
Roberto Cattaneo, MD, Lecco, ITALY
Francesco Guerreschi, MD, Lecco, ITALY Seventeen limb segments representing eight femora, six tibia and three humeri in nine patients with Ollier's disease were treated using the Ilizarov method. The mean lengthening achieved was 7.0 cm in the femur, 6.8 cm in the tibia and 7.5 cm in the humerus. The average duration of treatment was 7.5 months. Equal limb length was achieved in six of seven lower limbs. Multiplanar angular deformities were corrected in all the limb segments. With a mean follow-up of 4.3 years, the tissue transformation and corrections achieved are observed to be maintained. The corticotomy and tissue manipulation through the sites of the lesions achieved angular correction and lengthening and tissue transformation of the lesions. Moderator(s):Henry J. Mankin, MD, Boston, MA

85. Electricbrain Home: Index: Health: Conditions And Diseases: Rare Disorders: Olli
cache, Health Conditions and diseases Rare Disorders ollier disease News at 0730 on May 22, 2004 Random quote Go
http://www.electricbrain.com/index/Health/Conditions_and_Diseases/Rare_Disorders
electricbrain
Index
Health Conditions and Diseases ... Rare Disorders : Ollier Disease home index write privacy ... cache
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86. Bilateral Presentation Of The Ollier's Disease.A Case Report, And Literature Rev

http://www.medigraphic.com/ingles/i-htms/i-h-gral/i-hg2001/i-hg01-3/im-hg013f.ht

87. Maffucci's Syndrome - Eurorad - Clinical Case 2486 - Resident
Discussion. Maffucci s syndrome is multiple enchondromas with subcutaneous haemangiomas. The presence of haemangiomas distinguish it from ollier s disease.
http://www.eurorad.org/case.cfm?uid=2486

88. Bone Table Of Contents
Hereditary Multiple Exotosis (Osteochondromatosis). Enchondromatosis (ollier s disease). III. Bone Infections. General Considerations.
http://edcenter.med.cornell.edu/CUMC_PathNotes/Skeletal/Bone_TOC.html
BONE
Table of Contents
I. Normal
  • Bone Formation
  • Osteoblasts and Bone Matrix
  • Bone Mineralization
  • Osteoclasts and Bone Resorption
  • Bone Development
II. Congenital and Hereditary Bone Disorders
  • Achondroplasia
  • Osteogenesis Imperfecta (Brittle Bones, Fragilitas Ossium)
  • Osteopetrosis (Marble Bone Disease, Osteosclerosis)
  • Hereditary Multiple Exotosis (Osteochondromatosis)
  • Enchondromatosis (Ollier's Disease)
III. Bone Infections
  • General Considerations
  • Hematogenous (Pyogenic) Osteomyelitis
  • Osteomyelitis from a Contiguous Infection
  • Osteomyelitis from an Introduced Infection
  • Bone Tuberculosis
  • Bone Syphilis
  • Fungus Infections of Bone
IV. Metabolic Bone Diseases
  • General Considerations
  • Osteoporosis
  • Rickets and Osteomalacia
  • Bone Changes in Hyperparathyroidism (Generalized Osteitis Fibrosa Cystica, Von Recklinghausen's Disease of Bone)
  • Renal Osteodystrophy
  • Paget's Disease of Bone (Osteitis Deformans)
V. Fractures
  • General Considerations
  • Pathology
  • Clinical Aspects
VI. Other Nonneoplastic Disorders of Bone
  • Fibrous Dysplasia of Bone
  • Fibrous Cortical Defect and Nonossifying Fibroma
  • Solitary Bone Cyst (Unicameral Bone Cyst)
  • Aneurysmal Bone Cyst
  • Eosinophilic Granuloma of Bone
  • Bone Lesions of Gaucher's Disease
VII.

89. Bone Disease
are those with other primary lesions (Paget s disease, irradiation, bone infarcts, multiple osteochondromatosis, and ollier s disease.) Clinical Bone pain
http://www.geocities.com/CollegePark/Classroom/9056/bone.html
Bone Disease Hereditary bone disease Metabolic bone disease Infectious bone disease Bone tumors Hereditary bone disease Diseases of abnormal growth plate maturation (osteochondrodysplasia).
    Achondroplasia Osteogenesis Imperfecta (OI) This condition represents a group of inheritable disorders caused by abnormal type I collage synthesis. Aberrant collagen deposition in osteoid synthesis leads to "brittle bones". This condition may confuse social and health care workers in cases of potential child abuse. Clinical: Type I (A.D.) Multiple fractures in infancy. Blue sclera Poor dentition Hearing loss Kyphoscoliosis Type II (A.R.) Perinatal death Osteopetrosis (Marble bone disease of Albers-Schonberg) . Rare disease inheritable as either dominant or recessive trait. Recessive form is fatal during neonatal/infant stage. Clinical: Cortical overgrowth Pathologic fractures Anemia Cranial nerve entrapment Prognosis: Variable with bone marrow transplant. Metabolic Disease Osteoporosis Rickets/Osteomalacia Hyperparathyroidism This condition results from excessive PTH release. The primary form results from hyperplastic parathyroid tissue. The secondary form is typically a consequence of renal failure. Unchecked PTH release stimulates osteoclasts to resorb bone. Patients suffer from changes ocurring in bone and from the hypercalcemia that develops. Clinical: Osteitis fibrosa cystica Brown tumor Hypercalcemia Pathologic fractures

90. ACR Learning File Web
Sales. Click here for ordering information. Diagnosis Multiple enchondromatosis (ollier s disease). Return to top. Copyright © 1994
http://www.learningfile.com/learning_file/viewcase.php?section=sk&case_num=118

91. MedPix™ Radiology Teaching Files, Cases, And Medical Image
4314 - - Contributed by Fred R Brandon ( National Capital Consortium ) - - Author Info Diagnosis Enchondromatosis (ollier s disease) Dx confirmed
http://rad.usuhs.mil/medpix/medpix.html?mode=tf_case&pt_id=4314¬hing=

92. Dictionary Definition Of OLLIER
See ollier graft, ollier s disease, ollier s method, ollier s theory, ollierThiersch graft. Please select first two letters of word you are looking for.
http://www.dictionarybarn.com/OLLIER.php
Dictionary definition of OLLIER
Browse Dictionary by alphabet A B C D ... Z Top Words olamine
old

old age assistance

old growth
...
oligocene

Louis X.E.L., French surgeon, 1830-1900.
See: Ollier graft, Ollier's disease, Ollier's method, Ollier's theory, Ollier-Thiersch graft.
Please select first two letters of word you are looking for OA OB OC OD ... OZ fiSearchFormMaxSetId='AX006027'; Top Words oligochaeta
oligochete

oligocholia

oligochylia
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93. Tumors ChondrosarcID5063.txt
While most enchondromas are solitary, patients with ollier s disease and Maffucci s syndrome demonstrate multiple enchondromas.A minority (15%) of
http://www.infobiogen.fr/services/chromcancer/Tumors/chondrosarcID5063.html
Atlas of Genetics and Cytogenetics in Oncology and Haematology
Home Genes Leukemias Solid Tumours ... NA
Bone: Chondrosarcoma
Identity Figure 1: En bloc resection specimen of the proximal fibula of a 43 year old female, containing a lobulated bluish white, translucent tumour (4.5 x 2 x 1.9 cm) located centrally within the medullary cavity, consistent with central chondrosarcoma
Figure 2: Corresponding macro-slice showing a lobular architecture, and endosteal cortical thinning. Cytonucle ar appearance can be more readily appreciated in figure 3 Classification Note approximately 90% of chondrosarcomas are histologically of the conventional type; in addition to conventional chondrosarcoma, some rare variants with distinctive microscopic and clinical features are discerned: clear cell chondrosarcoma (1%), mesenchymal chondrosarcoma (2%), juxtacortical chondrosarcoma (2%) and extra-skeletal myxoid chondrosarcoma (5%). Furthermore, dedifferentiated chondrosarcoma is a relatively rare high grade sarcoma next to a low-grade conventional malignant cartilage-forming tumor, comprising 6-10% of all chondrosarcomas. Conventional chondrosarcomas can be categorized according to their location in bone. The majority of chondrosarcomas (75%) are located centrally within the medullary cavity (central chondrosarcoma), a small percentage of which arise within a preexisting benign precursor (enchondroma). While most enchondromas are solitary, patients with Ollier's disease and Maffucci's syndrome demonstrate multiple enchondromas.A minority (15%) of chondrosarcomas develops from the surface of bone (peripheral chondrosarcoma) as a result of malignant transformation within the cartilaginous cap of a solitary or hereditary pre-existent osteochondroma.

94. Tumors ChondromaID5147.txt
cartilage. The nonerheditary syndrome of multiple enchondromas or enchondromatosis is known as ollier s disease. Enchondromatosis
http://www.infobiogen.fr/services/chromcancer/Tumors/ChondromaID5147.html
Atlas of Genetics and Cytogenetics in Oncology and Haematology
Home Genes Leukemias Solid Tumours ... NA
Bone: Chondroma
Identity Note Chondroma is an uncommon benign tumour which characteristically forms mature cartilage. It is found mostly in the small bones of the hand and/or feet, although it can also occur in long, tubular bones, primarily the humerus, femur and ribs. Occasionally, focal areas of mixoid degeneration may result in a mistaken diagnosis of chondrosarcoma. Classification Chondromas are classified according to their location:
  • enchondroma: within the bone (within the medullary cavity),
  • periosteal chondroma: on the surface of the bone,
  • soft tissue chondroma in the soft tissue. Clinics and Pathology Disease Enchondroma Note Fig: Enchondroma in the distal portion of the femur shaft. (courtesy of Dr Henry DeGroot at http://www.drdegroot.com
    Enchondroma is usually a solitary benign lesion in intramedullary bone. Usually asymptomatic, it is incidentally discovered as a palpable bony nodule. Rarely, causes soft tissue swelling and pain at the lesion site. Pain can be a sign of pathologic fracture. Both sex are equally affected, and any age group can be involved. It is thought to develop from epiphyseal cartilage rests that subsequently proliferate and slowly enlarge. Approximately 50% of solitary enchondromas are found in the hands, typically in the middle and distal portions of the metacarpals and the proximal portions of the phalanges, 10% in the feet, 20% in the proximal and distal parts of the femur and the proximal part of the humerus.
  • 95. Blount's Disease, The Alfred I. DuPont Institute.
    rickets; osteomyelitis; trauma; ollier s disease; metaphyseal chondrodysplasia; focal fibrocartlaginous dysplasia. Classification Infantile
    http://gait.aidi.udel.edu/res695/homepage/pd_ortho/educate/clincase/blount.htm
    BLOUNT'S DISEASE
    STEVEN R. BOYEA, M.D., Resident, Orthopaedic Surgery J. RICHARD BOWEN, M.D., Chief, Orthopaedic Surgery June 10, 1996 CLINICAL CASE PRESENTATION ORTHOPAEDIC DEPARTMENT THE ALFRED I. DUPONT INSTITUTE WILMINGTON, DELAWARE CASE HISTORY: History : The patient is a 14 + 6 year old black male with a one year history of progressively worsening left knee pain. He states that the pain began in both knees and was intermittent, Tylenol helped alleviate the pain. Over the past 6 months the pain is more isolated to the left knee and has become constant in nature. Within the last 2 weeks the constant pain has become bad enough to limit his activities. He is unable to attend school or walk more than several hundred feet because of the pain. The pain is now affecting his sleep. He does get some relief with rest and elevation of the knee. The pain also limits his motion in that knee. He denies any trauma to the knee and has no other medical problems. He is not taking any medications. There is no family history of leg deformities. Physical Exam : The adolescent is a morbidly obese 14 + 6 year old black male. His extremity exam reveals an asymmetric pelvis with the right being elevated. There is a leg length inequality with the left leg being about 3.5 cm shorter than the right. He also demonstrates a significant proximal tibia vara of about 35

    96. Spyware
    Global database of spyware programs. Enter the name and find out if it's spyware or not.
    http://www.ollier-maffucci.org/

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