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         Ollier Disease:     more detail
  1. Molecular Profiling of Solitary and Ollier Disease-related Central Chondrosarcomas: An Investigation of DNA Aberrations, mRNA and Protein Expression by Leida B. Rozeman, 2005
  2. Allergy: The Facts (Oxford Medical Publications) by Robert J. Davies, Susan Ollier, 1989-05-18

1. NORD - National Organization For Rare Disorders, Inc.
ollier disease. To purchase fulltext report ($7.50) View Cart/Checkout. Copyright 1987, 1989, 1995, 1998, 2001 Synonyms of ollier disease Enchondromatosis;
http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Ollier Diseas

2. Ollier Disease
ollier disease is a rare skeletal disorder characterized by abnormal bone development (skeletal dysplasia). While this disorder may be present at birth (congenital); it may not become apparent growth, are more obvious. ollier disease primarily affects the long bones and
http://www.bchealthguide.org/kbase/nord/nord337.htm
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National Organization for Rare Disorders, Inc.
Ollier Disease
Important
It is possible that the main title of the report is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Synonyms
  • Multiple Enchondromatosis Multiple Cartilaginous Enchondroses Dyschondroplasia Enchondromatosis
Disorder Subdivisions
  • None
Related Disorders List
Information on the following diseases can be found in the Related Disorders section of this report:
  • Maffucci syndrome Multiple exostoses Proteus syndrome
General Discussion
Ollier disease is a rare skeletal disorder characterized by abnormal bone development (skeletal dysplasia). While this disorder may be present at birth (congenital); it may not become apparent until early childhood when symptoms, such as deformities or improper limb growth, are more obvious. Ollier disease primarily affects the long bones and cartilage of the joints of the arms and legs, specifically the area where the shaft and head of a long bone meet (metaphyses). The pelvis is often involved; and even more rarely, the ribs, breast bone (sternum), and/or skull may also be affected.
Ollier disease manifests as greater than normal growth of the cartilage in the long bones of the legs and arms so that growth is abnormal and the outer layer (cortical bone) of the bone becomes thin and more fragile. These masses of cartilage are benign (non-cancerous) tumors known as enchondromas. Enchondromas may occur at anytime. After puberty these growths stabilize as cartilage is replaced by bone. In rare cases, the enchondromas may undergo malignant changes (e.g., chondrosarcomas). The exact cause of Ollier disease is not known, although in some cases it may be inherited as an autosomal dominant genetic trait.

3. Ollier Disease
Enchondromatosis, or multiple enchondromas, refers to a group of disorders of which ollier disease is the best known. This is nonhereditary
http://www.stevensorenson.com/residents6/ollier_disease.htm

Home
Up Neurofibromatosis Pyknodysostosis ... Multiple hereditary exostoses [ Ollier disease ] Achondroplasia Diastrophic dwarfism Chondrodysplasia punctata Thanatophoric dwarfism ... Dyschondrosteoses Enchondromatosis, or multiple enchondromas, refers to a group of disorders of which Ollier disease is the best known. This is nonhereditary disorder which usually presents in childhood. Nominally, the disease consists of multiple enchondromas. However, on radiographs, streaks of low density are seen projecting through the diaphyses into the epiphyses of the long bones, due to ectopic cartilage deposits. With age, the cartilage may calcify in the typical "snowflake" pattern. The affected extremity is shortened (asymmetric dwarfism) and sometimes bowed due to epiphyseal fusion anomalies. Patients are at risk for development of sarcomas, specifically osteosarcomas and chondrosarcomas. These occur in approximately 25 % of patients. Mafucci syndrome represents enchondromatosis with oft tissue hemangiomas, usually in the hands and feet. As with Ollier disease, there is typically a shortening of the long bones. These patients are at higher risk for sarcomatous transformation of both the vascular and cartilaginous portions of the disease. REFERENCES Flemming DJ, Murphey MD. Enchondroma and chondrosarcoma. Semin Musculoskelet Radiol. 2000;4(1):59-71.

4. Ollier Disease
a CHORUS notecard document about ollier disease Disclaimer. Feedback. Search. ollier disease. multiple enchondromata. hamartomas of cartilage within bone
http://chorus.rad.mcw.edu/doc/00292.html
CHORUS Collaborative Hypertext of Radiology Musculoskeletal system
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Search
Ollier disease
  • multiple enchondromata
  • hamartomas of cartilage within bone
  • may be limited to one extremity or to extremities of one side
  • femur + tibia most often involved
  • may degenerate > chondrosarcoma
Cf: Mafucci syndrome Charles E. Kahn, Jr., MD - 2 February 1995
Last updated 26 May 2004

Medical College of Wisconsin

5. Ollier Disease And Maffucci Syndrome
ollier disease and Maffucci Syndrome. Introduction. Maffucci Syndrome. ollier disease. Introduction. Other benign cartilage tumors, besides those mentioned in this section, are ollier disease and Maffucci syndrome. enchondromas with normalappearing bones and, hence, they do not have ollier disease. ollier disease is a rare syndrome
http://www.ortho.hyperguides.com/Tutorials/tumor/ollier/tutorial.asp
window.location="http://www.ortho.hyperguides.com/";
Ollier Disease and Maffucci Syndrome Frank J. Frassica, MD
Franklin H. Sim, MD

Introduction
Other benign cartilage tumors, besides those mentioned in this section, are Ollier disease and Maffucci syndrome. Characteristics of Ollier disease include multiple enchondromatosis, usually unilateral benign cartilage tumors of bone.
Maffucci Syndrome
Ollier Disease
To make the diagnosis of Ollier disease, the bone should be dysplastic. The dysplatic bone is often shortened and bowed. Patients may have multiple enchondromas with normal-appearing bones and, hence, they do not have Ollier disease. Ollier disease is a rare syndrome. Historically, we are taught that approximately 30% of patients with Ollier disease will develop a chondrosarcoma. These are usually very low-grade lesions. If the patient has associated soft tissue angiomas, then the patient has Maffucci syndrome. The risk of chondrosarcoma in Maffucci syndrome may be as high as 100%. Again, these are low-grade chondrosarcomas. The patient is more typically to die from a high-grade visceral carcinoma, such as an astrocytoma, pancreatic tumor, liver tumor, or breast cancer.

6. Maffucci Syndrome
may be useful for a differential diagnosis ollier disease is a rare abnormal development of the bones (skeletal dysplasia) usually beginning in childhood.
http://www.bchealthguide.org/kbase/nord/nord433.htm
document.write(''); var hwPrint=1; var hwDocHWID="nord433"; var hwDocTitle="Maffucci Syndrome"; var hwRank="1"; var hwSectionHWID="nord433"; var hwSectionTitle=""; var hwSource="cn6.0"; var hwProdCfgSerNo="wsh_html_031_s"; var hwDocType="NORD";
National Organization for Rare Disorders, Inc.
Maffucci Syndrome
Important
It is possible that the main title of the report is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Synonyms
  • Dyschondrodysplasia with Hemangiomas Enchondromatosis with Multiple Cavernous Hemangiomas Hemangiomatosis Chondrodystrophica Kast Syndrome Multiple Angiomas and Endochondromas
Disorder Subdivisions
  • None
Related Disorders List
Information on the following diseases can be found in the Related Disorders section of this report:
  • Ollier Disease Klippel-Trenaunay-Weber Syndrome Blue Rubber Bleb Nevus Syndrome
General Discussion
Maffucci Syndrome is a rare genetic disorder characterized by benign overgrowths of cartilage (enchondromas), skeletal deformities, and dark red irregularly shaped patches of skin (hemangiomas). Enchondromas are most often found in certain bones (phalanges) of the hands and feet. Skeletal malformations may include legs that are disproportionate in length and/or abnormal side-to-side curvature of the spine (scoliosis). In many cases, bones may tend to fracture easily. In most cases, hemangiomas appear at birth or during early childhood and may be progressive. Maffucci Syndrome is inherited as an autosomal dominant genetic trait.

7. Ollier Disease
Home. Up. ollier disease. Opitz Syndrome. ollier disease. Ollier/Maffucci Self Help Group http//www.ollier-maffucci.org
http://www.medlina.com/ollier_disease.htm
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Ollier Disease
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Ollier Disease Ollier/Maffucci Self Help Group - http://www.ollier-maffucci.org
Information about the organization, and the diseases Olliers Disease and Maffucci Syndrome. Includes activities, services, membership, forums and chats. Virtual Children's Hospital - http://www.vh.org
A look at Enchondromatosis by Michael P. D'Alessandro, M.D. Includes clinical presentation, etiology and imaging findings. SUBCATEGORIES Up Search Now: info@medlina.com N ew Y ork C ity A merica M edica, I nc.

8. Ollier Disease - Information / Diagnosis / Treatment / Prevention
home rare disorders ollier disease ollier disease. Web Directory ? NORD ollier disease Sample report, plus links to organisations.
http://www.healthcyclopedia.com/rare-disorders/ollier-disease.html

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Related Topics: Musculoskeletal Disorders Medical Definition: University of Newcastle-upon-Tyne Medical Dictionary: "ollier disease" Health News: Search millions of published articles for news on Ollier Disease Modern Medicine Aging The Ardell Wellness Report HealthFacts Medical Post Medical Update Men's Health and the National Women's Health Report Note: Subscription required to access the full text of articles. Web Directory: NORD: Ollier Disease Sample report, plus links to organisations. [Fee required for full report] Virtual Children's Hospital: Enchondromatosis Clinical presentation, etiology and imaging findings. Notes: Healthcyclopedia presents health information in the form of websites and articles that encompass conventional medicine and alternative treatments Under no circumstances can it recommend or endorse a specific drug or therapy or treatment.

9. Health Library -
ollier disease is a rare skeletal disorder characterized by abnormal bone development (skeletal growth, are more obvious. ollier disease primarily affects the long bones and
http://www.yalenewhavenhealth.com/library/healthguide/IllnessConditions/topic.as

10. Musculoskeletal System - CHORUS
Charcot) joint; ochronosis; ollier disease; OsgoodSchlatter disease; osteitis fibrosa; osteochondroma (exostosis); osteochondrosis; osteochondrosis
http://chorus.rad.mcw.edu/index/6.html
CHORUS Collaborative Hypertext of Radiology Search by title
Musculoskeletal system
Charles E. Kahn, Jr., MD, Editor
26 May 2004

Medical College of Wisconsin

11. EHLERS-DANLOS SYNDROME ASSOCIATED WITH OLLIER DISEASE:14(3)
May 1994. EHLERSDANLOS SYNDROME ASSOCIATED WITH ollier disease. Mohammed Moussa, MCh(Ortho), PhD; Anwar Ul-Haque, FCAP; Ake Ahlberg, PhD.
http://www.kfshrc.edu.sa/annals/143/cr93181.html
May 1994
EHLERS-DANLOS SYNDROME ASSOCIATED WITH OLLIER DISEASE
Mohammed Moussa, MCh(Ortho), PhD; Anwar Ul-Haque, FCAP; Ake Ahlberg, PhD From the Departments of Orthopedic Surgery (Drs. Moussa and Ahlberg) and Pathology (Dr. Ul-Haque), King Fahd Hospital of the University,
Al-Khobar. Address reprints and correspondence to Dr. Moussa: Department of Orthopedic Surgery, King Fahd Hospital of the University, Department of Orthopedic Surgery, P.O. Box 40194, Al-Khobar 31952, Saudi Arabia. Accepted for publication 24 November 1993. The association of Ehlers-Danlos syndrome (EDS), a hereditary disorder of connective tissue, and Ollier disease, a rare, nonhereditary form of bone dysplasia, in a five-year-old female, is described. This association has not been reported before. The possibility of a common etiological factor is discussed.
Case Report
A five-year-old Syrian female presented with limping. She had a true shortening of the right lower limb of 4 cm. The skin was hyperextensible (Figure 1) but normal in texture. Joint hypermobility was prominent in the hands (Figure 2), feet and knees. She had 35_ and 15_ genu recurvatum for the right and left knee respectively (Figure 3). Sclerae, fundi, cornea, teeth and palate were normal. Two systolic clicks and a late systolic murmur were audible at the cardiac apex. The cardiac murmur increased in intensity on squatting, indicating asymptomatic mitral valve prolapse. FIGURE 1. Moderate skin hyperextensibility at the knee.

12. Health Library -
ollier disease. None. General Discussion. ollier disease is a rare skeletal disorder characterized by abnormal bone development (skeletal dysplasia).
http://yalenewhavenhealth.org/library/healthguide/IllnessConditions/topic.asp?hw

13. Disease Directory : Rare Disorders : Ollier Disease
Diseases Rare Disorders ollier disease. »»ollier disease Movie Reviews«« ollier disease Movie Reviews. Search ollier disease.
http://www.diseasedirectory.net/Rare_Disorders/Ollier_Disease/default.aspx
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14. Disease Directory : Ollier Disease
Diseases Rare Disorders ollier disease ollier disease. Directory Listing. Submit Your Site to the ollier disease category. Featured Partner.
http://www.diseasedirectory.net/detailed/27624.aspx
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Date Added:
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URL: http://www.iseekhealth.com/ollier_disease-2204.php

15. Ollier Disease And Maffucci Syndrome
ollier disease and Maffucci Syndrome. Frank J. Frassica, MD Chairman, Department of Orthopedic Surgery Robert A. Robinson Professor
http://www.ortho.hyperguides.com/Tutorials/tumor/ollier/default.asp
window.location="http://www.ortho.hyperguides.com/"; Ollier Disease and Maffucci Syndrome
Frank J. Frassica, MD
Chairman, Department of Orthopedic Surgery
Robert A. Robinson Professor of Orthopedic Surgery
The Johns Hopkins Hospital;
Professor of Oncology
Sidney Kimmel Comprehensive Cancer Center
Baltimore, Maryland Franklin H. Sim, MD
Consultant, Department of Orthopedic Surgery
Chairman, Department of Orthopedic Oncology
The Mayo Clinic Rochester, Minnesota

16. Ollier Disease
ollier disease Important It is possible that the main title of the report ollier disease is not the name you expected. Please check
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Health Topics Symptoms ... For a Complete Report Ollier Disease Important It is possible that the main title of the report Ollier Disease is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms
  • Multiple Enchondromatosis Multiple Cartilaginous Enchondroses Dyschondroplasia Enchondromatosis
Disorder Subdivisions
  • None
General Discussion Ollier disease is a rare skeletal disorder characterized by abnormal bone development (skeletal dysplasia). While this disorder may be present at birth (congenital); it may not become apparent until early childhood when symptoms, such as deformities or improper limb growth, are more obvious. Ollier disease primarily affects the long bones and cartilage of the joints of the arms and legs, specifically the area where the shaft and head of a long bone meet (metaphyses). The pelvis is often involved; and even more rarely, the ribs, breast bone (sternum), and/or skull may also be affected. Ollier disease manifests as greater than normal growth of the cartilage in the long bones of the legs and arms so that growth is abnormal and the outer layer (cortical bone) of the bone becomes thin and more fragile. These masses of cartilage are benign (non-cancerous) tumors known as enchondromas. Enchondromas may occur at anytime. After puberty these growths stabilize as cartilage is replaced by bone. In rare cases, the enchondromas may undergo malignant changes (e.g., chondrosarcomas). The exact cause of Ollier disease is not known, although in some cases it may be inherited as an autosomal dominant genetic trait.

17. Ollier Disease
ollier disease. ollier disease a CHORUS notecard document about ollier disease ollier disease. multiple enchondromata. ollier disease To make the
http://www.health-nexus.com/ollier_disease.htm
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Ollier Disease
Ollier disease a CHORUS notecard document about Ollier disease ... Ollier disease. multiple enchondromata. hamartomas of cartilage within bone ...
Ollier Disease and Maffucci Syndrome Ollier Disease and Maffucci Syndrome Frank ... MD Introduction Maffucci Syndrome Ollier Disease Introduction Other benign cartilage ... small round calcifications phleboliths). Ollier Disease To make the ...
Ollier Disease ...CATEGORIES Home Up Ollier Disease Opitz Syndrome Ollier Disease Ollier/Maffucci Self Help Group - http://www.ollier-maffucci.org...
Ollier disease ...Multiple hereditary exostoses ] [ Ollier disease ] [ Achondroplasia ] [ Diastrophic...a group of disorders of which Ollier disease is the best known. This is nonhereditary...in the hands and feet....
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The Contact a Family Directory - OLLIER'S DISEASE printer friendly, OLLIER'S DISEASE, ... Hospital, London, UK. OLLIER'S DISEASE SELF-HELP GROUP. Andrew Harter Ollier's Disease Self-Help Group ...

18. Musculoskeletal Conditions-Disorders
Muscular Dystrophy Myofascitis Myopathies Myotonic Dystrophy Nail Patella Syndrome ollier disease Osteomalacia Osteomyelitis
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19. Ollier Disease - Medical Dictionary Definitions Of Popular Medical Terms
MedicineNet Home MedTerms medical dictionary AZ List ollier disease. Advanced Search.
http://www.medterms.com/script/main/art.asp?articlekey=11765

20. Conditions And Diseases - Ollier Disease Top Links
ollier disease Web Site Links. Ollier chats. NORD ollier disease - A look at the alternate names, a general discussion and resources.
http://www.disease-resources.com/Top_Health_Conditions_and_Diseases_Rare_Disorde
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Ollier Disease Web Site Links Ollier/Maffucci Self Help Group Information about the organization, and the diseases Olliers Disease and Maffucci Syndrome. Includes activities, services, membership, forums and chats.
NORD - Ollier Disease
A look at the alternate names, a general discussion and resources.
Virtual Children's Hospital
A look at Enchondromatosis by Michael P. D'Alessandro, M.D. Includes clinical presentation, etiology and imaging findings.
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