1. Nephroblastoma - Part A Texas Children's Hospital, Houston, TX. nephroblastoma (WILMS TUMOR) Focal Anaplasia. Diffuse Anaplasia. nephroblastoma (Wilms Tumor) Epidemiology http://sup.ultrakohl.com/uscap/abs-1998/nephr-A.htm

Back to Pediatric Renal Home Page REVIEW OF PEDIATRIC RENAL NEOPLASMS John Hicks Texas Children's Hospital, Houston, TX NEPHROBLASTOMA (WILMS TUMOR) INDEX Epidemiology Clinical Features Cytogenetics Components and Histologic Patterns ... Diffuse Anaplasia Nephroblastoma (Wilms Tumor): Epidemiology Incidence 5 to 6% of All Childhood Cancers n United States Cases per year in United States African-Americans Gender Ratio (bilateral tumors) Mean Age for Unilateral Tumors Male Female Mean Age for Bilateral Tumors Male Female 90% Occur in Children 8.1 per million children Highest Incidence 41 months 47 months 29 months 33 months Nephroblastoma (Wilms Tumor): Clinical Features Bilateral Tumors Abdominal Mass Abdominal Pain Acute Abdomen Hypertension Fever Hematuria Weight Loss Urinary Tract Infection Nausea/Vomiting Urogenital Anomalies (Renal Ectopia, Unilateral Agenesis, Horseshoe Kidney, Ureteral Duplication, Hypospadias, Cryptorchidism) Hemihypertrophy Aniridia Nephroblastoma (Wilms Tumor): Cytogenetics WT1 Tumor Suppressor Gene: A Constitutional Deletion Chromosome 11p13 WAGR Syndrome Nonhereditary Wilms Tumor (33%) 10 Exons Encoding for a 45-49 kd Protein Homology to Early Growth Response 1 (EGR1) Sequence Specific DNA Binding Regulate Transcription of Other Genes 30 to 40% of Wilms with Loss of Heterozygosity for region with WT1

2. HONselect - Nephroblastoma Language MeSH term Accepted terms English nephroblastoma, Wilms Tumor - Wilms Tumor - nephroblastomas - Tumor, Wilms - Tumor, Wilms - Tumors, Wilms. http://www.hon.ch/HONselect/RareDiseases/C04.557.435.595.html

List of rare diseases: English Deutsch Language: MeSH term: Accepted terms: English: Nephroblastoma - Wilms Tumor - Wilms' Tumor - Nephroblastomas - Tumor, Wilms - Tumor, Wilms' - Tumors, Wilms Français: NEPHROBLASTOME - TUMEUR WILMS Deutsch: Nephroblastom - Gene, Wilms-Tumor - Wilms-Tumor Español: NEFROBLASTOMA - TUMOR DE WILMS Português: NEFROBLASTOMA - TUMOR DE WILMS HONselect ressources Definition: Yes Articles: Yes Images: No News: Yes Conferences: No Clinical trials: Yes Web sites: English Yes Français Yes Deutsch Yes Español Yes Português Yes Home About us Site map ... HONewsletter http://www.hon.ch/HONselect/RareDiseases/C04.557.435.595.html Last modified: Wed Apr 28 2004

3. Slide: Nephroblastoma (Wilms Tumor), Gross, Cut Surface nephroblastoma (Wilms tumor), gross, cut surface. Click picture to enlarge. Close window to return. Yellow white fleshy mass has been removed from the kidney. ( ), http://www.kumc.edu/instruction/medicine/pathology/ed/ch_16/c16_s11a.html

Nephroblastoma (Wilms tumor), gross, cut surface Click picture to enlarge. Close window to return Yellow white fleshy mass has been removed from the kidney.

4. Uhrad.com - Pediatric Imaging Teaching Files uhrad.com Pediatric Imaging Teaching Files. Case Forty Eight - Wilm's Tumor (nephroblastoma) Click on Images for Enlarged View Clinical History 18-month-old female with palpable abdominal mass. Discussion Wilm's tumor (nephroblastoma) is the most common abdominal malignancy, and the http://www.uhrad.com/pedsarc/peds048.htm

uhrad.com - Pediatric Imaging Teaching Files Case Forty Eight - Wilm's Tumor (Nephroblastoma) Click on Images for Enlarged View Clinical History: 18-month-old female with palpable abdominal mass. Findings: Ultrasound: Large inhomogeneous mass arising from the upper right kidney. Multiple areas of decreased echogenicity are present compatible with necrosis. MRI: The mass demonstrates heterogeneous low T1 and high T2 signal characteristics with areas of high T1 signal corresponding with hemorrhage. A pseudocapsule is evident on T2 imaging. There is no involvement of the renal vein or IVC. Diagnosis: Wilm's tumor (nephroblastoma). Discussion: Wilm's tumor (nephroblastoma) is the most common abdominal malignancy, and the most common solid renal mass in childhood. The incidence is 1 in 10,000 with a bimodal peak at ages 2.5 and 3.5 years (1). There are both hereditary and sporadic forms, and approximately 6% are bilateral(1). Most are unicentric and arise from the kidney. Extra-renal Wilm's tumor is rare. Associated conditions include congenital genitourinary malformations, hemihypertrophy, sporadic aniridia, as well as Beckwith-Weidemann and Drash syndromes. nephroblastomatosis (residual metanephrogenic blastema beyond 36 weeks gestation) is also associated with Wilm's tumor and is considered by many its precursor.

5. Nephroblastoma Case Forty Eight Wilm's Tumor (nephroblastoma) Click on Images for Enlarged View Diagnosis Wilm's tumor (nephroblastoma). Discussion Wilm's tumor (nephroblastoma) is the http://www.health-nexus.com/nephroblastoma.htm

Health-Nexus.Net Health-Nexus.Org The #1 Health information site Home ... Up Search Health-Nexus for: Match ALL words Match ANY word Email this page to a friend ! Post a question or comment on our Message Board Home Page Health Specialties Health News ... Alternative Health Options Substance Abuse Animal Health Search: Books Magazines Video Keywords: Find it Here Nephroblastoma See Also Wilm's Tumor Nephroblastoma ... NEPHROBLASTOMA (WILMS TUMOR). ... Nephroblastoma (Wilms Tumor): Epidemiology. Incidence ... 29 months 33 months. Nephroblastoma (Wilms Tumor): Clinical Features. ... Pediatric Imaging Teaching Files ...Files Case Forty Eight - Wilm's Tumor (Nephroblastoma) Click on Images for Enlarged View...vein or IVC. Diagnosis: Wilm's tumor (nephroblastoma). Discussion: Wilm's tumor (nephroblastoma) is the... Nephroblastoma Nephroblastoma Back to previous level WAGR Syndrome Search PUBMED for WAGR Syndrome: All Review Therapy Diagnosis .... Wilms' tumor - UMMC Medical Encyclopedia article ... is a cancerous tumor of the kidney that occurs in children. Alternative Names: Nephroblastoma; Kidney tumor Causes, incidence, and risk factors: Wilms' tumor is one of the ...

6. NEPHROBLASTOMA Welcome to . Advertisement. nephroblastoma Wilms tumor, or nephroblastoma, is a cancerous tumor of the kidney in children. Wilms is the most common tumor of the kidney and the most common intra-abdominal tumor in children. http://www.medhelp.org/glossary/new/gls_3021.htm

Welcome to .... Advertisement NEPHROBLASTOMA - Wilms tumor , or nephroblastoma , is a cancerous tumor of the kidney in children. Wilms is the most common tumor of the kidney and the most common intra-abdominal tumor in children. The exact cause is unknown, but probably develops in fetal tissue due to an underlying genetic factor. Med Help International Search Ask the Doctor Forums Patient Network The medical glossary has been made possible by a generous donation from: (revised: 1996) Advertisement

7. InteliHealth: Nephroblastoma What Is It? Wilms tumor, also called nephroblastoma, is the most common form of kidney cancer to affect children. It is the sixth http://www.intelihealth.com/IH/ihtIH/WSIHW000/9339/24569.html

chrome_imgPreload('gifChr_mid_but_home_mo_1','http://img.intelihealth.com/i/C/Chr_mid_but_home-o.gif'); chrome_imgPreload('gifChr_mid_but_comm_mo_2','http://img.intelihealth.com/i/C/Chr_mid_but_comm-o.gif'); chrome_imgPreload('gifChr_mid_but_dental_mo_3','http://img.intelihealth.com/i/C/Chr_mid_but_dental-o.gif'); chrome_imgPreload('gifChr_mid_but_drug_mo_4','http://img.intelihealth.com/i/C/Chr_mid_but_drug-o.gif'); chrome_imgPreload('gifChr_mid_but_askexpert_mo_5','http://img.intelihealth.com/i/C/Chr_mid_but_askexpert-o.gif'); chrome_imgPreload('gifChr_mid_but_medical_mo_6','http://img.intelihealth.com/i/C/Chr_mid_but_medical-o.gif'); chrome_imgPreload('gifChr_mid_but_chats_mo_7','http://img.intelihealth.com/i/C/Chr_mid_but_chats-o.gif'); chrome_imgPreload('gifchr_mid_but_news_mo_8','http://img.intelihealth.com/i/c/chr_mid_but_news-o.gif'); chrome_imgPreload('gifChr_mid_but_privacy_mo_9','http://img.intelihealth.com/i/C/Chr_mid_but_privacy-o.gif'); Advertisement Wilms' Tumor What Is It? Symptoms Diagnosis Expected Duration ... Additional Info What Is It? Wilms' tumor, also called nephroblastoma, is the most common form of kidney cancer to affect children. It is the sixth most common form of childhood cancer, and accounts for 5 percent to 6 percent of all childhood cancers in the United States. Wilms' tumor develops when malignant kidney cells multiply out of control, and eventually form a firm, grayish or tan mass (tumor). This mass usually is smooth and fairly round. As it enlarges, Wilms' tumor changes the normal shape and appearance of the kidney. It also can destroy areas of normal kidney tissue, and can cause bleeding into the urine. In some cases, the tumor eventually grows so large that it becomes noticeable as a firm, smooth lump in a child's flank or abdomen. Without proper treatment, Wilms' tumor has the potential to spread outside the kidney, most commonly to the lungs and the liver.

8. HON Mother & Child Glossary, Childhood Cancers: Wilms' Tumour Wilms tumour or nephroblastoma is a cancer of the kidneys that can develop in a foetus but may not cause symptoms for years after birth. http://www.hon.ch/Dossier/MotherChild/child_cancer/cancer_wilms.html

Introduction Reproduction Pregnancy During Pregnancy ... Glossary A-Z Childhood Illness Bacteria Virus Cancer Gastrointestinal ... Mental Health Childhood Cancers: Wilms' Tumour Description Wilms' tumour or nephroblastoma is a cancer of the kidneys that can develop in a foetus but may not cause symptoms for years after birth. Wilms' tumour usually occurs in children under 5 years of age, although it appears occasionally in older children and rarely in adults. The cause of Wilms' tumour isn't known, although a genetic abnormality may be involved. Children with certain birth defects , such as absence of the irises (eye structure) or excessive growth of one side of the body, both of which may be caused by a genetic abnormality, have an increased risk of developing Wilms' tumour. Symptoms and Signs Symptoms include a large abdomen (for example, a rapid change to a larger diaper size), abdominal pain, fever, poor appetite, nausea, and vomiting. Blood appears in the urine in 15 to 20% of cases. Wilms' tumour may cause high blood pressure. This cancer can spread to other parts of the body, especially the lungs, producing a cough and shortness of breath. Diagnosis and Treatment If a child has symptoms, the doctor will usually feel the child's abdomen for lumps and run blood and urine tests. If Wilms' tumour is suspected, an

9. ClinicalTrials.gov - Information On Clinical Trials And Human Research Studies: Tract and Sexual Organs, and Pregnancy nephroblastoma. Include trials that are Sarcoma; Germ Gell Neoplasm; Liver Neoplasm; nephroblastoma; Osteosarcoma; Rhabdomyosarcoma; Sarcoma http://clinicaltrials.gov/ct/screen/BrowseAny?path=/browse/by-condition/hier/BXS

10. Nephroblastoma - Part C TX. nephroblastoma (WILMS TUMOR). INDEX. nephroblastoma Anaplasia (Unfavorable Histology. Atypical (bizarre) mitotic figures Enlarged http://sup.ultrakohl.com/uscap/abs-1998/nephr-C.htm

Back to Pediatric Renal Home Page REVIEW OF PEDIATRIC RENAL NEOPLASMS John Hicks Texas Children's Hospital, Houston, TX NEPHROBLASTOMA (WILMS TUMOR) INDEX Epidemiology Clinical Features Cytogenetics Components and Histologic Patterns ... Diffuse Anaplasia Nephroblastoma: Anaplasia (Unfavorable Histology Atypical (bizarre) mitotic figures adjacent cell Nuclear hyperchromatism Prognosis and anaplasia (diffuse) 55% relapse rate 48% mortality rate Nephroblastoma: Favorable Histology Lack of diffuse anaplasia Tubular predominant better prognosis than blastemal predominant Teratoid Wilms (adipose tissue, cartilage, squamous cells, glands): Better Prognosis Adenofibroma appearance: Better prognosis Nephroblastoma: Focal Anaplasia Anaplastic nuclear changes within discrete focus/foci in primary intrarenal tumor Anaplasia absent in tumor extension beyond tumor capsule No evidence of severe nuclear atypia elsewhere in yumor With more than 1 focus, anaplastic area surrounded by non-anaplastic tumor

11. ClinicalTrials.gov - Information On Clinical Trials And Human Research Studies: Resources Help What's New About. Browse By Condition By Disease Heading Cancers and other Neoplasms nephroblastoma. Include trials that are no longer recruiting patients. 16 studies were found. Sarcoma; Germ Gell Neoplasm; Liver Neoplasm; nephroblastoma; Osteosarcoma; Rhabdomyosarcoma; Sarcoma http://clinicaltrials.gov/ct/screen/BrowseAny?path=/browse/by-condition/hier/BC0

12. Nephroblastoma nephroblastoma. Image URL Glomerulus in Wilm s tumour, Image URL nephroblastoma, Image URL nephroblastoma, Image URL nephroblastoma, Image URL nephroblastoma, http://www.brisbio.ac.uk/ROADS/subject-listing/nephroblastoma.html

A collection of medical, dental and veterinary images for use in teaching. Home About the Archive FAQ Terms and Conditions ... Help Nephroblastoma Glomerulus in Wilm's tumour Nephroblastoma Nephroblastoma Nephroblastoma Nephroblastoma Nephroblastoma Nephroblastoma Nephroblastoma Nephroblastoma in striated muscle Nephroblastoma in striated muscle Ruptured Wilm's tumour Wilm's tumour Wilm's tumour Wilm's tumour Wilm's tumour Wilm's tumour in smooth muscle of tubules Wilm's tumour in striated muscle Wilm's tumour in striated muscle Wilm's tumour in striated muscle Wilm's tumour in striated muscle Wilm's tumour in tubules Wilm's tumour including muscle cells Wilm's tumour Wilm's tumour Wilm's tumour Wilm's tumour Wilm's tumour Wilm's tumour Wilm's tumour Wilm's tumour

13. Wilm's Tumor (Nephroblastoma) Wilms’ Tumor (nephroblastoma). What is Wilms’ Tumor (nephroblastoma)? nephroblastoma, or Wilms’ Tumor, is the most common solid http://www.pedisurg.com/PtEduc/Wilms_Tumor.htm

(Nephroblastoma) The information above, although based on a thorough knowledge and careful review of current medical literature, is the opinion of the doctors at Texas Pediatric Surgical Associates and is presented to inform you about surgical conditions. It is not meant to contradict any information you may receive from your personal physician and should not be used to make decisions about surgical treatment. If you have any questions about the information above or your child's care, please contact our doctors at any time by calling (713) 704-5869. [Home Page] [General Surgery] [Urology] [ENT] ... [Patient Education Files]

14. Slide: Nephroblastoma (Wilms Tumor), Photomicrograph, H&E nephroblastoma (Wilms tumor), photomicrograph, H E Click picture to enlarge. Close window to return Small blue tumor cells with http://www.kumc.edu/instruction/medicine/pathology/ed/ch_16/c16_s11b.html

Click picture to enlarge. Close window to return Small blue tumor cells with poorly formed glomerular and tubular structures are typical.

15. Nephroblastoma Medical Encyclopdia article about nephroblastoma nephroblastoma. A Medical Encyclopedia Article provided by the University of Maryland Medical A resource with information on over 4000 medical http://www.umm.edu/medical-terms/04004.htm

Nephroblastoma A Medical Encyclopedia Article provided by the University of Maryland Medical System A resource with information on over 4000 medical topics including: Nephroblastoma Previous Next

16. Nephroblastoma Information Diseases Database 2 synonyms or equivalents were found. nephroblastoma aka/or Wilms tumour Medical information linksnephroblastoma specific sites. http://www.diseasesdatabase.com/ddb8896.htm

Diseases Database Index Sponsors Contact ... Previous Page Nephroblastoma Information Search 2 synonyms or equivalents were found. Nephroblastoma aka/or Wilms' tumour may cause or feature (Follow link for list) risk factors may include (Follow link for list) may be allelic with (Follow link for list) belong(s) to the category of (Follow link for list) Nephroblastoma: Definition(s) via UMLS Code translations and terms via UMLS Nephroblastoma: specific sites Send Nephroblastoma to medical search engines (JavaScript enabled browsers only) If your browser has no JavaScript you can still use these: Search using Internet medical databases Search using Internet search engines (non-specialist) We subscribe to the HONcode principles of the Health On the Net Foundation i-medicine.info - the evidence based medicine, informatics and audit portal Valid XHTML 1.0 Served 2004-06-03 01:03:57 Metadata Updated 2004-05-22

17. Entrez PubMed Abstract, Survival in nephroblastoma treated according to the trial and study SIOP9/GPOH with respect to relapse and morbidity. Ann Oncol. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&db=PubMed&term=Nephrobl

18. Entrez PubMed Successful management of inferior vena cava and right atrial nephroblastoma tumor thrombus with preoperative chemotherapy. Oberholzer http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1

19. Nephroblastoma - Medical Dictionary Definitions Of Popular Medical Terms Learn about Arthritis. http://www.medterms.com/script/main/art.asp?articlekey=13510

20. LookSmart - Directory - Nephroblastoma Or Wilm's Tumor nephroblastoma or Wilm s Tumor Resources on the cause, symptoms, signs, diagnosis, treatment, and research of this condition. http://search.looksmart.com/p/browse/us1/us317837/us317920/us53948/us66254/us914

@import url(/css/us/style.css); @import url(/css/us/searchResult1.css); Home IN the directory this category YOU ARE HERE Home Personal Health Genitourinary Nephroblastoma or Wilm's Tumor - Resources on the cause, symptoms, signs, diagnosis, treatment, and research of this condition. Directory Listings About Cancer.gov - Wilms' Tumor Thorough examination of the ailment and its potential treatments. Information is intended for doctors and other health-care practitioners. Children's Cancer Web - Wilms' Tumor Children's Cancer Web posts a general background about the affliction, as well as a page of links to other pages on the subject. Oxford University, Dept. of Pediatrics - CCRG Childhood Cancer Research Group offers details about current research, plus a guide to resources on childhood cancer. We're always looking for ways to improve your search experience. Tell us how we're doing. Join the Zeal community and help build the "Nephroblastoma or Wilm's Tumor" Directory Category IN the directory this category About Us Advertise with Us Advertiser Log-in Terms of Service

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