61. NARCOLEPSY narcolepsy. Complaint of sleepiness or sudden muscle weakness. Further reading references. narcolepsy Med Standford. Bassetti, C. Aldrich, M. narcolepsy. http://neuroland.com/sleep/narcolepsy.htm

Neuroland Neurology information Click on the brain to index page Search NeuroLand Neuro disease Notes ... Neuro Med NARCOLEPSY Complaint of sleepiness or sudden muscle weakness Recurrent daytime naps or lapses into sleep that occur almost daily Overview Male = female Prevalence: about 1 in 4000 in North America and Europe (Hublin et al 1994) Onset: 20 to 40 years old, rarely before age 5 or after age 60. Polysomnography: short sleep latency, short REM sleep latency. Clinical symptoms Excessive sleepiness: Most common initial symptom Sleepiness is similar to those caused by sleep deprivation: most apparent in boring, sedentary situations and is partially relieved by movement. No amount of nighttime or daytime sleep produces full alertness. Cataplexy: Episodic weakness without altered consciousness lasting seconds to minutes. Precipitated by excitement or emotion: may occur several times daily or less than once per month. Laughter is the most common precipitant. Anger, embarrassment, excitement, and other forms of emotion also can induce it. Severe attacks produce complete paralysis of striated muscles, but respiratory muscles are spared.

62. Howstuffworks "What Is Narcolepsy?" Main Science ShortStuff What is narcolepsy? are treated with medication so that this doesn t happen. Symptoms of narcolepsy. http://health.howstuffworks.com/question676.htm

ComputerStuff AutoStuff ElectronicsStuff ScienceStuff ... PeopleStuff Top Subjects Car Engines Lock Picking Nuclear Bombs Tattoos ... Gas Turbine Engines Sponsored By: Categories Earth Science Engineering Life Science Military ... Browse the Science Library Explore Stuff Lidrock.com Big List of Articles Get the Newsletter Shop or Compare Prices ... Search HSW and the Web Search Google Main Science ShortStuff What is narcolepsy? What you've seen in the movies is partly true narcoleptics do suddenly fall asleep, but most are treated with medication so that this doesn't happen. Symptoms of Narcolepsy Excessive daytime sleepiness - the overwhelming urge to fall asleep during the day, even after having plenty of sleep the night before Cataplexy - a sudden, usually brief attack of general muscle weakness related to a strong emotional response (fear, anger, laughter) Hypnagogic sleep paralysis - brief episodes of paralysis that occur when falling asleep Hypnopompic sleep paralysis - brief episodes of paralysis that occur when waking up Hypnagogic hallucinations - vivid, usually visual or auditory hallucinations that occur at the onset of sleep (sometime between falling asleep and the actual sleep state)

63. VCUHS Sleep Disorders Center Located in Richmond, Virginia. Information on apnea, narcolepsy, insomnia, RLS, and links to other sites. http://www.vcu.edu/sleepwell

VCU Health System Virginia Commonwealth University last updated: May 3, 2002

64. Narcolepsy – Symptoms & Treatment What is narcolepsy? Did you know? About Hypocretin activates arousal and regulates sleep. What are the symptoms of narcolepsy? In http://www.helpguide.org/aging/narcolepsy.htm

ON THIS PAGE: What is narcolepsy? What are the symptoms of narcolepsy? How is narcolepsy diagnosed? What is the treatment for narcolepsy? ... Related topics What is narcolepsy? Did you know? About one in 2,000 people suffers from narcolepsy. The majority of narcoleptics first experience symptoms between the ages of 15 and 30. For those who do not understand narcolepsy, it may seem funny to think of someone unable to control himself or herself from suddenly falling asleep. Narcolepsy is a very serious condition, though, and one that has several serious repercussions. For the person with narcolepsy, waking hours can be danger zones depending on the task at hand. Most activities, including driving, working, or even cooking, might be dangerous if the person doing them falls asleep unexpectedly. Narcolepsy is a chronic neurological disorder that is the second leading cause of excessive daytime sleepiness after obstructive sleep apnea. People with narcolepsy experience daytime sleepiness and intermittent, uncontrollable episodes of falling asleep during the day.

65. Narcolepsy, MSLT, Sleep Apnea, Wakefulness Test, Obstructive Sleep Apnea, Polyso Do I Have narcolepsy? . Lawrence Martin, MD, FACP, FCCP. Here s a little quiz. One or more statements may be correct. People with narcolepsy often http://www.mtsinai.org/pulmonary/Sleep/narcolepsy.htm

"Do I Have Narcolepsy?" Lawrence Martin, M.D., FACP, FCCP Here's a little quiz. One or more statements may be correct. People with narcolepsy often: a) fall asleep during the day at inappropriate times b) have episodes of muscle weakness brought on by emotions such as laughing c) have nightmares just when they start to fall asleep. d) have feelings of paralysis during sleep Most people associate narcolepsy with "sleep attacks" or "falling asleep at inappropriate times." But that is just one aspect of narcolepsy. There can be associated nightmares at the start of sleep and episodes of Sleep paralysis . Even more common are sudden episodes of muscle weakness while awake, called 'cataplexy', which may herald a sleep attack. The answers are all correct. Conversely, just because someone falls asleep at inappropriate times (answer a) doesn't mean he or she has narcolepsy. The most common causes of excessive daytime sleepines, in fact, do not include narcolepsy. Far more common are simple sleep deprivation and obstructive sleep apnea Here are complaints from five patients. Which one likely has narcolepsy?

66. American Sleep Association Professional sleep organization focusing on sleep apnea, snoring, insomnia, and narcolepsy. Aims to improve sleep health around the world by educating health care providers and increasing public awareness about sleep health and sleeping disorders. http://www.americansleepassociation.org

Home About ASA Join Online for Free Contact Us ... Corporations www.AMERICANSLEEPASSOCIATION.org Home About ASA Join ASA Chat / Messages ... Contact Us American Sleep Association The American Sleep Association is the first organization to link all people interested in sleep health and sleep disorders around the continent. The goal of the association is to be a complete source for sleep information and communication for all people interested in sleep and sleep disorders. The American Sleep Association aims to improve sleep health around the country by educating health care providers and increasing public awareness about sleep health and sleeping disorders. Research Updates Sleep in the news More News Search Media Computers Shareware Usenet Health Politics Employment Sports Kids Education Business Sciences Entertainment The Web New! TECH SECTION

67. The Best Is Yet.net: Narcolepsy In Our Family Virginia Ramage Smith describes the experience of narcolepsy in a family member. http://www.thebestisyet.net/cgi-bin/cgiwrap/pando19/start.cgi/viewfrom11.htm

B Wednesday, June 2, 2004 Search our site: 4 EASY STEPS to Great Eldercare and Beyond ASSESS LOCATE SELECT LINKS by topic by state/country GAMES ... CONTACT US Subscribe to our free bi-weekly newsletter fresh articles about aging - delay it - even reverse it; stretching your retirement dollars - for seniors and their families; view from the chair; and, updates, new features, and specials Subscribe Here! Your First Name: Your Last Name: Your Email Address: We never share your name or email address with any other company or individual . . .period! Find Great Senior Housing Instant Download! Like most of us, Virginia Ramage Smith has opinions, and she's not shy about sharing them. Unlike most of us, she is chairman of a corporate board and a full-time caregiver for her husband, a victim of Alzheimer's disease. She shares her opinions and experiences weekly in this column. Read more of her articles in our VRS section.

68. Narcolepsy Back to table of contents. narcolepsy Mateen Ahmed, MD. Historical aspects 1862 Caffe describes cases of hypersomnia that later came to be called narcolepsy ; http://sleepmed.bsd.uchicago.edu/narcolepsy.html

Back to table of contents Narcolepsy Mateen Ahmed, MD. Produced by The Sleep Research Laboratory The University of Chicago Wallace Mendelson MD, Director Scenario: A 17 y/o female with excessive daytime sleepiness: Linda is a 17 y/o female who c/o being tired and sleepy during daytime. When she feels sleepy, a brief nap is refreshing. When playing soccer, she fell when she had a clear opportunity to score a goal. She later confided to her mother that she lost strength at that moment. What is the most likely explanation of her symptoms? Narcolepsy Narcolepsy is a disorder of unknown etiology, which is characterized by excessive sleepiness, typically associated with cataplexy and other REM sleep phenomena such as sleep paralysis and hypnagogic hallucinations. Historical aspects 1862 Caffe describes cases of hypersomnia that later came to be called "narcolepsy" 1880 Gelaneau describes "narcolepsy" and the tetrad. 1963 Rechtschaffen et al. and Takahashi and Jimbo, independently report nocturnal sleep onset REM periods in narcolepsy. Main symptoms Excessive daytime sleepiness.

69. NARCOLEPSY The summary for this Japanese page contains characters that cannot be correctly displayed in this language/character set. http://karin.sakura.ne.jp/~kuni/

NARCOLEPSY ƒuƒƒO‰»(5ŒŽ–^) ŠúŠÔŒÀ’茾‚¢–óƒMƒƒƒ‰ƒŠ[ “Šeƒ~ƒX‚ª‚È‚¯‚ê‚΂±‚¿‚ç‚Ìver.‚ðo‚·‚Í‚¸‚Å‚µ‚½(‚‰ü—Ç”Å)B ƒ‚ƒ‚“W‚Ì‚æ‚è‚àˆóÛ‚ª‚â‚â‹­‚¢‚ÆŽv‚í‚ê‚Ü‚·B ‰ü—ǔŃAƒbƒv‚Ü‚Å‚Ì‚¨’ƒ‚É‚²‚µÎB •ÊƒAƒ“ƒOƒ‹‚ŃŒƒ“ƒ_ƒŠƒ“ƒO‚µ‚½‚¾‚¯‚Å‚·B •W€‚̃Œƒ“ƒ_ƒ‰[ŽŽ‚»‚¤‚Æ‚µ‚½‚çA ‹üÜE‚c‚n‚e‚ ‚½‚è‚ō·‚ª‚Å‚½‚Á‚Û‚¢B ‚È‚ñ‚Æ‚È‚­ŠG‰æ’²‚É‚µ‚Ä‚Ý‚é‚©‚ƃeƒXƒgB ‚¤[‚ñŽ¸”sB ‚ß‚ª‚Ë(H)–³‚µ¥¥¥B ‚»‚ë‚»‚ëƒgƒbƒvƒy[ƒW®—‚µ‚È‚¢‚ƁAA Lightwave8²²Ö²²Ö[I(¥Í¥) PROFILE GALLERY MOVIE DIARY maybe...everyday BBS sometime PICTBBS sometime EXTRA LINK MAIL since 2000-12-9 (C) Kuniomi.I ƒŠƒ“ƒN‚É2Œ’ljÁ[ “ú‹L‚ðƒuƒƒO‰» ƒŠƒ“ƒN‚É2Œ’ljÁ[ ƒvƒƒtƒB[ƒ‹”÷–­‚ɍXV ƒgƒbƒv‚¢‚ë‚¢‚ë‚ƍXV Link free ! Previous 5 Skip Previous Previous Next ... List

70. Ohio Sleep Medicine Institute Ohio Sleep Clinic with many helpful links and a lot of information for sufferers of Restless Legs Syndrome, Periodic Limb Movement Disorder, Sleep Apnea, narcolepsy and other sleep disorders. http://www.sleepohio.com/

Our total effort is focused on improving the quality of life for those experiencing sleep disorders.

71. Site On Narcolepsy A personal view from a retired psychiatrist on narcolepsy and related conditions. http://www.gta.igs.net/~ecahoon

THIS SITE DOES NOT SUPPORT FRAMES. Download the latest version now and take advantage of this site in frames

72. Narcolepsy - UMMC An indepth report on the causes, diagnosis, treatment, and prevention of narcolepsy. narcolepsy. WHAT IS narcolepsy? The word narcolepsy http://www.umm.edu/patiented/articles/what_narcolepsy_000098_1.htm

Home Medical Reference Patient Education Narcolepsy WHAT IS NARCOLEPSY? The word narcolepsy comes from two Greek words that can be roughly translated as seized by numbness. The two primary symptoms in narcolepsy reflect this phrase: Excessive daytime sleepiness, with frequent daily sleep attacks or a need to take several naps during the day. Temporary and sudden muscle weakness (called cataplexy ), usually brought on by strong emotions. Some, but not all patients experience other symptoms: Microsleep episodes, in which the patient behaves automatically but without conscious awareness. A sense of paralysis that occurs between wakefulness and sleep (called atonia Dream-like states between waking and sleeping (called hypnagogic hallucinations Periodic leg movements during sleep ( periodic limb movement disorder REM (rapid eye movement) sleep is abnormal in narcolepsy. In fact, narcolepsy is sometimes defined as the loss of boundaries between wakefulness, non-REM sleep, and REM sleep. [For a full definition of REM and nonREM sleep, see box Healthy Sleep.]

73. Discovery Health Narcolepsy narcolepsy is a chronic sleep disorder that causes excessive, overwhelming daytime sleepiness. search, narcolepsy. By Terry Mason, MPH. http://health.discovery.com/diseasesandcond/encyclopedia/2912.html

74. OUR EXPERIENCES WITH NARCOLEPSY - Index Offers stories about experiences with symptoms, doctors, medicines and everyday life. http://www.cataplexic.com/narcolepsy2.html

This site is yours just as much as it is mine and I appreciate every contribution that you make. Anytime you have anything to add, just let me know...my email box is below. Again, thanks and bless you all. - Melody Be sure and visit the Narcolepsy Message Board and Help Forum Ask/answer questions of other narcoleptics. OUR EXPERIENCES WITH NARCOLEPSY Main Page UPDATED 05-25-04 Hi, my name is Melody and I have narcolepsy. This section is for fellow narcoleptics and their families to share their stories. If you have a story you would like to share, just email me and I will post it here. If you are in need of help or information, I will post your email address (unless you request otherwise) so that others who might be able to help can contact you. Narcolepsy is a lonely disorder...we all know that... and it is always nice to find out that we are not alone. Index for "Our Experiences" Click on the page number you want to go to.

75. WELCOME TO NAPPS WEB SITE NAPPS narcolepsy Action for Positive Practical Solutions. This is the start page for the NAPPS web site, a UK organisation to http://www.napps.cwc.net/

NAPPS is a new support group based in the UK and was initially set up by a Narcolepsy sufferer from Yorkshire. NAPPS provides support, advice and information for Narcoleptics and other groups and individuals wishing to learn more about the condition. NAPPS hopes to offer Narcoleptics the opportunity to form contacts and links with other sufferers through the use of the Internet. The organisation aims to raise awareness about the condition through producing publications, local and national media, education and community involvement. NAPPS is keen to collaborate with other organisations and service providers both nationally and internationally. This web site is just the start for us, and we are hoping to add more pages of interest to our visitors. If you have any suggestions or wish to consider an article for inclusion in the site, please contact us (email: napps@cwcom.net ). We hope you find the site informative and return to see what's new sometime in the future. If you are viewing this site at low resolution, you'll find you need to scroll down most pages. The NAPPS logo appears at the bottom of each page... just click it to return to the top.

76. NHLBI, Narcolepsy Image of the Cover linked to PDF file. Facts About narcolepsy. narcolepsy is a chronic sleep disorder with no known cause. The main http://www.nhlbi.nih.gov/health/public/sleep/narcolep.htm

HOME SITE INDEX CONTACT US TIPS ... Publications Facts About Narcolepsy Narcolepsy is a chronic sleep disorder with no known cause. The main characteristic of narcolepsy is excessive and overwhelming daytime sleepiness, even after adequate nighttime sleep. A person with narcolepsy is likely to become drowsy or to fall asleep, often at inappropriate times and places. Daytime sleep attacks may occur with or without warning and may be irresistible. These attacks can occur repeatedly in a single day. Drowsiness may persist for prolonged periods of time. In addition, nighttime sleep may be fragmented with frequent wakenings. 4 pages. NIH Publication No. 96-3649 You may obtain the document in following ways: View online (in formats below) [ASCII document, 20 K] [PDF document, 176 K, need Acrobat Reader to review] Information for visitors using screen readers Information about PDF Printed Copies Order online Order by telephone, fax, or mail

77. CENTER FOR NARCOLEPSY Includes information on treatment, pointers to latest research and publications, their current research and information on the basic mechanisms of narcolepsy. http://med-www.stanford.edu/school/Psychiatry/narcolepsy/

Narcolepsy is a serious medical disorder and a key to understanding other sleep disorders Narcolepsy is a disabling illness affecting more than 1 in 2,000 Americans. Most individuals with the disorder are not diagnosed and are thus not treated. The disease is principally characterized by a permanent and overwhelming feeling of sleepiness and fatigue. Other symptoms involve abnormalities of dreaming sleep, such as dream-like hallucinations and finding oneself physically weak or paralyzed for a few seconds (see Symptoms). The Stanford University Sleep Clinic was the first medical clinic ever established to specialize in sleep disorders. It was founded in the early 1970s by Dr. William Dement to diagnose and treat narcoleptic patients. The Stanford Center for Narcolepsy was established in the 1980s and is now directed by Drs. Emmanuel Mignot and Seiji Nishino. The Center for Narcolepsy is part of the Department of Psychiatry and Behavioral Sciences and has published more than 100 articles on narcolepsy. It is the world leader in narcolepsy research. Several hundred patients with the disorder are currently treated at the Center or participate in various research protocols. Other research protocols are conducted in animals models of narcolespy. The Stanford Center for narcolepsy was the first to report that narcolepsy-cataplexy is caused by hypocretin (orexin) abnormalities in both animal models and humans (see Research). We are always looking for volunteers in our narcolepsy research studies.

78. Narcolepsy: Description, Criteria, Causes, Symptoms, Treatments And Medications . narcolepsy is sudden overwhelming daytime sleepiness that lasts for 10 to 15 minutes....... narcolepsy. Also known as http://www.mental-health-matters.com/disorders/dis_details.php?disID=63

79. Erowid GHB Vault : Patent #2 Patent Number US4738985. Pharmaceutical composition and treatment of narcolepsy. Kluger; Ronald, et. al. narcolepsy and insomnia are widely occurring. http://www.erowid.org/chemicals/ghb/ghb_patent2.shtml

Become a member and choose a used book from our collection as a gift! United States Patent Patent Number: US4738985 Pharmaceutical composition and treatment of narcolepsy Kluger; Ronald, et. al. Date of Patent: Apr. 19, 1988 Inventors: Kluger; Ronald (Don Mills, CA) Mamelak; Mortimer (Willowdale, CA) Assignee: The University of Toronto Innovations Foundations (Toronto, CA; Assignee type: Foreign Company or Corporation) Appl. Number: Filed: Mar. 19, 1986 Related U.S. Application data CROSS REFERENCE TO RELATED APPLICATION This is a Continuation-in-Part of application serial number 06/637,882 filed Aug. 6, 1984 and now U.S. Pat. No. 4,599,355. Int. Cl.-4 U.S. Cl. Field of Search References Cited OTHER PUBLICATIONS Chem. Abst. 93-148042f (1980). Primary Examiner - Friedman; Stanley J. ABSTRACT Sleep disorders in mammals, such as insomnia and narcolepsy, are treated by administering an effective amount of ethyl 4-acetoxybutanoate, or a closely related homolog thereof. The compounds may also be administered to mammals to cause muscle relaxation and as animal anaesthetics. Moreover the compounds appear to inhibit the release of dopamine in the brain, and are hence useful also in treatment of conditions which are associated with abnormalities of dopamine release and dopamine sensitivities, such as Parkinson's disease, schizophrenia and tardive dyskenesia. 10 CLAIMS FIELD OF THE INVENTION This invention relates to chemotherapeutic compounds and compositions, useful in the treatment of sleep disorders and other abnormalities in mammals.

80. The Florida Narcolepsy Association Support group for people with sleep disorders. http://flnarcolepsy.org/

The Florida Narcolepsy Association PO Box 15352 Sarasota, Fl 34277-1352 Welcome! The Florida Narcolepsy Association is a collective of people that "helps" or "comforts" others. This is the idea behind the Florida Narcolepsy Association to be there to lend a hand toward those afflicted, as well as their families, doctors and friends. Home Sleep Net ~ Everything you wanted to know about sleep but were too tired to ask The Sleep Medicine Home Page ~ A master TOC to sleep on the web by Dr. Michael Thorpy, Director of the Sleep-Wake Disorders at Montefiore Hospital, Bronx, New York. Sleepwell ~ Reservoir of information on sleep disorders. Cephalon ~ An international biopharmaceutical company dedicated to the discovery, development and marketing of products to treat neurological disorders and cancer. Breaking news about Modofinal/Provigil. Talk About Sleep ~ All sleep, all the time! The information of the FNA site is not intended to be medical advice. If you think that you have a sleep disorder you should seek care from a qualified health care professional.

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