41. Muscular Dystrophy Cerebral palsy, muscular dystrophy, spina bifida, Retts syndrome Apr 2004; muscular dystrophies of latter onset myDr muscular dystrophies (MD) of latter onset http://www.healthinsite.gov.au/topics/Muscular_dystrophy

42. Muscular Dystrophies - Information / Diagnosis / Treatment / Prevention home neurological disorders muscle diseases muscular dystrophies muscular dystrophies. Information • Diagnosis • Treatment • Prevention. http://www.healthcyclopedia.com/neurological-disorders/muscle-diseases/muscular-

Home Health cyclopedia All Topics by Category The Good Health Search Engine Health Conditions A-Z Gurus ... muscle diseases > muscular dystrophies Muscular Dystrophies Information / Diagnosis / Treatment / Prevention External links (marked with an arrow ) open in a new window. This site is a web directory and does not offer medical advice. We cannot take responsibility for information found on listed sites. This Page Subtopics Related Topics Medical Definition Health Portals ... Web Directory: Subtopics: Muscular Dystrophies > Mailing Lists Muscular Dystrophies > Organizations Muscular Dystrophies > Personal Pages Related Topics: Genetic Disorders Open Directory: Regional/Europe/United Kingdom/Health/Conditions and Diseases/Neurological Disorders/Muscular Dystrophies Medical Definition: University of Newcastle-upon-Tyne Medical Dictionary: "muscular dystrophy" Health Portals: MayoClinic.com Health News: Search millions of published articles for news on Muscular Dystrophies Modern Medicine Aging The Ardell Wellness Report HealthFacts Medical Post Medical Update Men's Health and the National Women's Health Report Note: Subscription required to access the full text of articles.

43. Muscular Dystrophy Muscular dystrophy. Definition The group of diseases called muscular dystrophies (MD) includes many inherited disorders such as http://www.healthscout.com/ency/article/001190.htm

Advertisement Search HealthScout Web MEDLINE Special Offers TV Specials Top Features Schizophrenia Hair Loss Liver Disease Allergies ... Impotence Resources Healthscout News 3D Interactive Human Atlas Health Videos Health Encyclopedia ... Drug Library Channels Home Today Women Men ... Drug Checker Advertisement Disease Injury Nutrition Poison ... Prevention Muscular dystrophy Definition: A group of disorders characterized by progressive muscle weakness and loss of muscle tissue. Alternative Names: Inherited myopathy; MD Causes, incidence, and risk factors: The group of diseases called muscular dystrophies (MD) includes many inherited disorders such as: Becker's muscular dystrophy Duchenne muscular dystrophy facioscapulohumeral muscular dystrophy limb-girdle muscular dystrophy Emery-Dreifuss muscular dystrophy myotonic dystrophy myotonia congenita These disorders are distinguished from each other by the type of inheritance (sex-linked, dominant gene , recessive gene ), the age when symptoms appear, and the types of symptoms that develop. Because these are inherited disorders, risks include a family history of muscular dystrophy. Lambert-Eaton syndrome and myasthenia gravis also have symptoms that may be similar to early stages of some types of muscular dystrophies, so these disorders must be ruled out when muscular dystrophies are diagnosed.

44. Muscular Dystrophy Hub muscular dystrophies by the Merck Manual. muscular dystrophies and Myopathies - by the University of Chicago Department of Neurology. http://www.healthubs.com/dystrophy/

Muscular dystrophy refers to a group of genetic diseases characterized by progressive weakness and degeneration of the skeletal or voluntary muscles which control movement. The major forms of muscular dystrophy include Duchenne, Becker, myotonic, limb-girdle, facioscapulohumeral, congenital, oculopharyngeal, distal and Emery-Dreifuss. Duchenne is the most common form of muscular dystrophy affecting children, and myotonic muscular dystrophy is the most common form affecting adults. Acne Allergy Antibiotics Antioxidants ... Wedding Overviews - Full text articles - Fact sheets NINDS Muscular Dystrophy (MD) Information Page - by The National Institute of Neurological Disorders and Stroke, National Institutes of Health. Muscular Dystrophy by Lucile Packard Children's Hospital Testimony on Muscular Dystrophy, February 27, 2001 - statement of Audrey S. Penn, M.D. Acting Director, National Institute of Neurological Disorders and Stroke. Muscular Dystrophy by the University of Maryland Medicine Limb-Girdle Muscular Dystrophy - by the Center for Human Genetics, Duke University Medical Center. Muscular Dystrophies - by the Merck Manual.

45. Diagnose-Me: Conditions: Muscular Dystrophy Some of these muscular dystrophies result in premature death; others may allow the person to live for decades with varying degrees of disability. http://www.diagnose-me.com/cond/C454168.html

Home FAQ Start The Analyst Last updated: May 06, 2004 Muscular Dystrophy Signs, symptoms and indicators Treatment recommendations Muscular dystrophy is one of a number of muscular diseases (myopathies) characterized by progressive muscle weakness and loss of muscle tissue. It is caused by an inherited genetic abnormality whereas other myopathies, such as polymositis, can be caused by an abnormality of the immune system . These disorders can develop at any time from birth through adulthood. There are many types of muscular dystrophy (MD). These diseases are classified according to the muscle groups involved and the age of onset. Some of these muscular dystrophies result in premature death; others may allow the person to live for decades with varying degrees of disability. MD is characterized by muscle weakness in various parts of the body, depending on its type. Muscle weakness worsens over time; initial symptoms usually develop gradually. MD includes many inherited disorders such as: Becker's muscular dystrophy Duchenne muscular dystrophy facioscapulohumeral muscular dystrophy limb-girdle muscular dystrophy Emery-Dreifuss muscular dystrophy myotonic dystrophy myotonia congenita These disorders are distinguished from each other by the type of inheritance (sex-linked, dominant gene, recessive gene), the age when symptoms appear, and the types of symptoms that develop. Because these are inherited disorders, risk factors include a family history of muscular dystrophy.

46. EPodiatry muscular dystrophies. Comments Muscular dystrophy Association. URL http//www.emedicine.com/pmr/topic65.htm. Comments Childhood muscular dystrophies. http://www.epodiatry.com/education_sub3.asp?topic=Pediatrics&sub1=Learning resou

47. News In DMD News in Muscular Dystrophy. 17/04/04 IN PRESS (Neuromuscular Disorders, 2004) Inducing muscle hypertrophy as a therapeutic strategy for muscular dystrophies. http://www.distrofiamuscular.net/news.htm

News in Muscular Dystrophy We need treatments to stop/slow the progression of DMD.....the parents need safe and complete information.....see the best informations of treatments in FFF -fight for a future.... Message Board Clinical Trials david-feder@uol.com.br BRAZILIAN RESEARCH CENTER - IMPORTANT INFORMATIONS NEW JUNE/2004 IN PRESS (Neuroscience Letters, 2004): Cardiomyopathy in Muscular Dystrophy Workshop 28–30 September 2003, Tucson, Arizona Clinical Recomendations: MAY/2004 Therapeutic gene transfer to dystrophic diaphragm by an adenoviral vector deleted of all viral genes NEW Cardiopulmonary failure in Duchenne muscular dystrophypathophysiology and management NEW Decreased total nitric oxide production in patients with duchenne muscular dystrophy NEW Ultrastructural changes in muscular tissues of dystrophin/utrophin double-knockout mice after bone marrow-derived mesenchymal stem cell transplantation NEW 18/05/04: Creatine monohydrate enhances strength and body composition in Duchenne muscular dystrophy NEW Tarnopolsky, M.A. MD, PhD; Mahoney, D.J. BSc; Vajsar, J. MD; Rodriguez, C. BSc; Doherty, T.J. MD, PhD; Roy, B.D. PhD; Biggar, D. MD

48. AllRefer Health - Muscular Dystrophy (Inherited Myopathy, MD) Muscular Dystrophy. Overview, Causes, Risk Factors. The group of diseases called muscular dystrophies (MD) includes many inherited disorders such as http://health.allrefer.com/health/muscular-dystrophy-info.html

AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia You are here : AllRefer.com Health Muscular Dystrophy Muscular Dystrophy Definition Prevention Treatment Expectations or Prognosis ... Go To Main Page Alternate Names : Inherited Myopathy, MD Definition A group of disorders characterized by progressive muscle weakness and loss of muscle tissue. Superficial Anterior Muscles The group of diseases called muscular dystrophies (MD) includes many inherited disorders such as: Becker's muscular dystrophy Duchenne muscular dystrophy facioscapulohumeral muscular dystrophy limb-girdle muscular dystrophy Emery-Dreifuss muscular dystrophy myotonic dystrophy myotonia congenita These disorders are distinguished from each other by the type of inheritance (sex-linked, dominant

49. Muscular Dystrophy . The muscular dystrophies include Duchenne...... decline. Nine types of muscular dystrophies are generally recognized. http://www.ehendrick.org/healthy/000925.htm

MAIN SEARCH INDEX Muscular dystrophy Definition Description Causes and symptoms Diagnosis ... Resources Definition Muscular dystrophy is the name for a group of inherited disorders in which strength and muscle bulk gradually decline. Nine types of muscular dystrophies are generally recognized. Description The muscular dystrophies include: Duchenne muscular dystrophy (DMD): DMD affects young boys, causing progressive muscle weakness, usually beginning in the legs. It is the most severe form of muscular dystrophy. DMD occurs in about 1 in 3,500 male births, and affects approximately 8,000 boys and young men in the United States. A milder form occurs in very few female carriers. Becker muscular dystrophy (BMD): BMD affects older boys and young men, following a milder course than DMD. BMD occurs in about 1 in 30,000 male births. Emery-Dreifuss muscular dystrophy (EDMD): EDMD affects young boys, causing contractures and weakness in the calves, weakness in the shoulders and upper arms, and problems in the way electrical impulses travel through the heart to make it beat (heart conduction defects). Fewer than 300 cases of EDMD have been identified. Limb-girdle muscular dystrophy (LGMD): LGMD begins in late childhood to early adulthood and affects both men and women, causing weakness in the muscles around the hips and shoulders. It is the most variable of the muscular dystrophies, and there are several different forms of the disease now recognized. Many people with suspected LGMD have probably been misdiagnosed in the past, and therefore the prevalence of the disease is difficult to estimate. The number of people affected in the United States may be in the low thousands.

50. InteliHealth: Muscular Dystrophy Muscular Dystrophy. Symptoms. Symptoms of muscular dystrophies, as well as their age of onset, vary according to the specific form of illness http://www.intelihealth.com/IH/ihtIH/WSIHW000/9339/10383.html

chrome_imgPreload('gifChr_mid_but_home_mo_1','http://img.intelihealth.com/i/C/Chr_mid_but_home-o.gif'); chrome_imgPreload('gifChr_mid_but_comm_mo_2','http://img.intelihealth.com/i/C/Chr_mid_but_comm-o.gif'); chrome_imgPreload('gifChr_mid_but_dental_mo_3','http://img.intelihealth.com/i/C/Chr_mid_but_dental-o.gif'); chrome_imgPreload('gifChr_mid_but_drug_mo_4','http://img.intelihealth.com/i/C/Chr_mid_but_drug-o.gif'); chrome_imgPreload('gifChr_mid_but_askexpert_mo_5','http://img.intelihealth.com/i/C/Chr_mid_but_askexpert-o.gif'); chrome_imgPreload('gifChr_mid_but_medical_mo_6','http://img.intelihealth.com/i/C/Chr_mid_but_medical-o.gif'); chrome_imgPreload('gifChr_mid_but_chats_mo_7','http://img.intelihealth.com/i/C/Chr_mid_but_chats-o.gif'); chrome_imgPreload('gifchr_mid_but_news_mo_8','http://img.intelihealth.com/i/c/chr_mid_but_news-o.gif'); chrome_imgPreload('gifChr_mid_but_privacy_mo_9','http://img.intelihealth.com/i/C/Chr_mid_but_privacy-o.gif'); Advertisement Muscular Dystrophy What Is It? Symptoms Diagnosis Expected Duration ... Additional Info What Is It? Muscular dystrophy refers to a group of genetic (inherited) conditions that cause progressive deterioration of the body's muscles, with increasing weakness and disability. These include:

51. HHMI News: Researchers Identify Defect That Causes Rare Muscular Dystrophies Researchers Identify Defect that Causes Rare muscular dystrophies. This work demonstrates that dystroglycan has two roles in the http://www.hhmi.org/news/campbell4.html

RESEARCH NEWS RESEARCH NEWS GRANT ANNOUNCEMENTS SCIENCE EDUCATION NEWS INSTITUTE NEWS ... Download this story in Acrobat PDF format. (requires Acrobat Reader Researchers Identify Defect that Causes Rare Muscular Dystrophies "This work demonstrates that dystroglycan has two roles in the brain: a developmental role and a synaptic role," said HHMI investigator Kevin Campbell. Subtle defects in the processing of a single protein that provides structural integrity to muscle cells can lead to several devastating forms of muscular dystrophy, according to studies by Howard Hughes Medical Institute researchers and their colleagues at the University of Iowa. The scientists reported in two papers published in the July 25, 2002, issue of the journal Nature that defects in enzymes responsible for the processing of the structural protein dystroglycan are the underlying cause of several rare forms of muscular dystrophy that affect muscles and cause additional developmental brain abnormalities including mental retardation. The new findings will immediately help doctors in providing accurate diagnosis and appropriate genetic counseling to patients and their families. In the longer term, knowing the underlying cause of the muscular dystrophies will help researchers tailor their interventions, according to Howard Hughes Medical Institute investigator

52. Muscular Dystrophy Dystrophinassociated proteins and the muscular dystrophies. Ann Rev Med 1997;48457-466; Cwik VA. Molecular basis of muscular dystrophies. http://www.5mcc.com/Assets/SUMMARY/TP0604.html

Muscular dystrophy DESCRIPTION: Inherited, progressive diseases of muscle with wide ranges of clinical expression. Included: Congenital muscular dystrophy (CMD) Congenital myotonic dystrophy Duchenne's muscular dystrophy (DMD) Becker's muscular dystrophy (BMD) Myotonic dystrophy Fascioscapulohumeral dystrophy (FSHD) Limb girdle muscular dystrophy (LGMD) Emery-Dreifuss muscular dystrophy (ED) Oculopharyngeal muscular dystrophy (OPMD) System(s) affected: Musculoskeletal, Nervous Genetics: See Causes and Risk factors Incidence/Prevalence in USA: Duchenne's muscular dystrophy (DMD): 1 per 3000 male births Myotonic dystrophy: 1 per 10,000 births Predominant age: Birth to infancy: Congenital muscular dystrophy with or without cerebral involvement, congenital myotonic dystrophy Infancy to early childhood: Duchenne's muscular dystrophy (DMD), Becker's muscular dystrophy (BMD), fascioscapulohumeral dystrophy (FHSD) Late childhood to adolescence: BMD, FSHD, myotonic dystrophy Predominant sex: CAUSES: X-linked: Some ED have mutation of gene at Xq28 for production of "Emerin" Autosomal dominant: Myotonic dystrophy have expanded CTG repeat of the gene at chromosome 19 ("Myotonin"); OPMD have mutation of gene at chromosome 14 ("PolyA-binding protein 2"); LGMD: Caveolin-3 gene mutation. Anticipation in successive generations were seen in myotonic dystrophy and OPMD. Autosomal dominant forms of ED can be resulted from mutation of Lamin A/C at chromosome 1.

53. Becker Muscular Dystrophy, BMD,Becker Muscular Dystrophy, BMD,Benign Pseudohyper The muscular dystrophies are a group of genetic disorders, which cause muscle weakness. Are other muscular dystrophies difficult to distinguish from BMD? http://www.icomm.ca/geneinfo/becker.htm

Becker Muscular Dystrophy, BMD,Becker Muscular Dystrophy, BMD,Benign pseudohypertrophic muscular dystrophy For Information on Workshops and Seminars for Special Needs Children click here The GAPS INDEX to Information on the Internet about Genetic Disorders and Birth Defects Genetic Information and Patient Services, Inc. (GAPS) HOME DISORDERS GLOSSARY Becker Muscular Dystrophy Also known as: BMD Benign pseudohypertrophic muscular dystrophy (as defined by the Muscular Dystrophy Association Quick Definition - Onset: Adolescence or adulthood. Symptoms: Generalized weakness and muscle wasting affecting limb and trunk muscles first. Calves often enlarged. Almost identical to Duchenne but often much less severe. Can be significant heart involvements. Progression: Disease progresses slowly and with variability but will affect all voluntary muscles. Survival well into mid to late adulthood. Inheritance: X-linked recessive (females are carriers). (as defined at http://www.beckermusculardystrophy.org/

54. Scapular Fixation In Muscular Dystrophy (Cochrane Review) In facioscapulohumeral muscular dystrophy (and occasionally in other muscular dystrophies) there is selective weakness of the thoracoscapular muscles which may http://www.update-software.com/abstracts/AB003278.htm

From The Cochrane Library, Issue 2, 2004 Scapular fixation in muscular dystrophy (Cochrane Review) Mummery CJ, Copeland SA, Rose MR ABSTRACT Order full review View and/or submit comments What's new in this issue Search abstracts ... Browse by Review Group A substantive amendment to this systematic review was last made on 11 February 2003. Cochrane reviews are regularly checked and updated if necessary. Background: Winging of the scapula is caused by weakness of the thoracoscapular muscles, which allows the scapula to lift off the chest wall during shoulder movements. In facioscapulohumeral muscular dystrophy (and occasionally in other muscular dystrophies) there is selective weakness of the thoracoscapular muscles which may spare other shoulder muscles such as the deltoid muscle. This imbalance results in significant winging and loss of shoulder function. Historically, a number of different surgical and non-surgical interventions have been used to achieve scapular stability. This review examines the evidence available for the use of all scapular fixation techniques in muscular dystrophy, especially facioscapulohumeral muscular dystrophy. Objectives: To examine the evidence for the relative efficacy of scapular fixation techniques in muscular dystrophy (especially facioscapulohumeral muscular dystrophy) in improving upper limb function.

55. Encyclopaedia Topic : Muscular Dystrophy, Section : Introduction The muscular dystrophies are a group of over 20 hereditary muscle disorders in which slow, progressive muscle wasting occurs, leading to increasing weakness http://www.nhsdirect.nhs.uk/en.asp?TopicID=319

56. BBC News | HEALTH | Gene Clue To Muscular Dystrophy diseases. . He added We believe that this mechanism may well be recognised in many more forms of muscular dystrophies in the future. . http://news.bbc.co.uk/hi/english/health/newsid_1703000/1703476.stm

CATEGORIES TV RADIO COMMUNICATE ... INDEX SEARCH You are in: Health Front Page World UK ... AudioVideo SERVICES Daily E-mail News Ticker Mobiles/PDAs Feedback ... Low Graphics Wednesday, 12 December, 2001, 00:00 GMT Gene clue to muscular dystrophy Muscular dystrophy is caused by genetic mutations Scientists have discovered a genetic link between two types of a severe muscle-wasting disease. They say the discovery brings them closer to understanding muscular dystrophy which until recently has baffled doctors. This is a valuable finding Sarah Yates, Muscular Dystrophy Campaign Scientists from Hammersmith Hospital in London and Oxford University have found that a newly discovered gene when mutated is responsible for both congenital and limb girdle muscular dystrophy. Congenital MD usually affects infants while limb girdle MD can start in late childhood or adulthood and generally causes weakness in the shoulder or pelvic girdle. 'Rewarding' Professor Francesco Muntoni from Hammersmith Hospital said the discovery could help improve diagnoses and treatment of patients. "The identification of this new disease gene has been particularly rewarding. We initially recognised this form of congenital muscular dystrophy as a novel and distinct clinical entity.

57. Laboratory For Gene Therapy Of Muscular Dystrophies Laboratory for Gene Therapy of muscular dystrophies. At least 25% of these biopsies are taken from patients with muscular dystrophies. http://www.lmb.uni-muenchen.de/groups/hl/welcome.html

Laboratory for Gene Therapy of Muscular Dystrophies GenZentrum Muscular dystrophies like Duchenne's muscular dystophy (DMD) are amongst the most common hereditary diseases and lead to severe disability and early death. Alternative treatments are not available. Therefore, a successful treatment modality such as somatic gene therapy would constitute substantial clinical and economical benefit. We are confident that we will be able to develop viral vectors and treatment modalities for DMD which will allow to replace a sufficient amount of functionally adequate dystrophin and to significantly improve the clinical phenotype. Furthermore, the results of this project are expected to pave the way for designing efficient gene therapy protocols for other genetic diseases of skeletal muscles, as well as other organs. We will address key scientific and practical issues that must be resolved before human trials of gene therapy for hereditary muscular dystrophies such as DMD can be contemplated. A network of collaborations has been established: The Friedrich-Baur-Institut (director: Prof. Dr. D. Pongratz) is one of the most important centers for the diagnosis and treatment of neuromuscular diseases in Germany. More than 500 muscle biopsies per year are processed. At least 25% of these biopsies are taken from patients with muscular dystrophies.

58. ClinicalTrials.gov - Information On Clinical Trials And Human Research Studies: 2. Recruiting, Study of Albuterol and Oxandrolone in Patients With Facioscapulohumeral Dystrophy (FSHD) Condition muscular dystrophies. http://www.clinicaltrials.gov/ct/gui/action/FindCondition?ui=D009136

59. HealthCentral - General Encyclopedia - Muscular Dystrophy Muscular dystrophy. LambertEaton syndrome and myasthenia gravis have symptoms that may be similar to early stages of some of the muscular dystrophies. http://www.healthcentral.com/mhc/top/001190.cfm

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60. Muscular Dystrophy Fact Sheet At Disability Network - The Network Of Disabled In Fact Sheet Muscular Dystrophy (MD). muscular dystrophies can be defined a type of disease which results in wasting of muscles of the body. http://www.disabilitynet.org.in/facts/md.htm

Fact Sheet Index Fact Sheet : Muscular Dystrophy (MD) Muscular dystrophies can be defined a type of disease which results in wasting of muscles of the body. Generally it is a very disabling disease. The various type of muscular dystrophies are given below : Duchenne Muscular Dystrophy (DMD) Becker Muscular Dystrophy (BMD) onset of the disease is adolescence or adulthood. Symptoms are nearly identical to Duchenne but often much less severe. Genetic reference : X-linked recessive (i.e.females are carriers). Limb-Girdle Muscular Dystrophy (LGMD) onse is in late childhood to middle age. Symptoms are weakness and wasting affecting shoulder and pelvic girdles first. Progression is usually slowly with cardiopulmonary complications often occurring in later stages of the disease. Genetic reference : Autosomal recessive, X-linked recessive. Facioscapulohumeral Muscular Dystrophy (FSH or FSHD) National Muscular Dystrophy Organisations : www.mdausa.org Muscular Dystrophy Association of America www.mda.org.au

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