81. Multiple Myeloma multiple myeloma. Leukaemia Research Fund produces a booklet on multiple myeloma, which provides general information on the disease. http://dspace.dial.pipex.com/lrf-/diseases/myeloma.htm

home patient information multiple myeloma Multiple myeloma Leukaemia Research Fund produces a booklet on Multiple Myeloma, which provides general information on the disease. To download this booklet as a PDF click here . To view a copy of this booklet click here Useful links for health professionals Patient publications on the web Reviews Key information Teaching aids ... Scientific meetings Multiple myeloma is a form of cancer which affects plasma cells in the bone marrow. These are cells which normally produce antibodies. They are a specialised form of B-lymphocyte. The condition is called multiple myeloma because most patients have evidence of disease at a number of different bony sites in the body. Synonyms: Myeloma See also: Plasma Cell Leukaemia Solitary Plasmacytoma Index of available booklets... Adult Acute Lymphoblastic Leukaemia Adult Acute Myeloid Leukaemia Childhood Acute Lymphoblastic Leukaemia Childhood Acute Myeloid Leukaemia Coping With Childhood Leukaemia Amyloidosis Aplastic Anaemia Burkitt's Lymphoma Chronic Lymphocytic Leukaemia Chronic Myeloid Leukaemia Essential Thrombocythaemia Fanconi's Anaemia Hairy Cell Leukaemia Histiocytosis Hodgkin's Disease Immune Thrombocytopaenic Purpura Large Granular Lymphocytic Leukaemia Mast Cell Leukaemia Monoclonal Gammopathy of Unknown Significance

82. Multiple Myeloma multiple myeloma Myeloma. Plasmacytoma. Hematology and Oncology multiple myeloma Marrow, Hematology and Oncology multiple myeloma Marrow. (Click image to enlarge). http://www.fpnotebook.com/HEM136.htm

Home About Links Index ... Editor's Choice document.write(code); Advertisement Hematology and Oncology Marrow Anemia ... Fanconi Anemia Assorted Pages Macroglobulinemia Multiple Myeloma Myelofibrosis Polycythemia Rubra Vera ... Bone Marrow Aspiration Multiple Myeloma Myeloma Plasmacytoma Book Home Page Cardiovascular Medicine Dentistry Dermatology Emergency Medicine Endocrinology Gastroenterology General Medicine Geriatric Medicine Gynecology Hematology and Oncology HIV Infectious Disease Jokes Laboratory Neonatology Nephrology Neurology Obstetrics Ophthalmology Orthopedics Otolaryngology Pediatrics Pharmacology Prevention Psychiatry Pulmonology Radiology Rheumatology Sports Medicine Surgery Urology Chapter Hematology and Oncology Index Anemia Cancer Coagulopathy Cardiovascular Medicine Dermatology Endocrinology Otolaryngology Examination Gastroenterology Hemoglobin Hemolysis Histiocytosis HIV Infectious Disease Laboratory Leukemia General Pulmonology Lymph Marrow Neurology Obstetrics Orthopedics Pediatrics Pharmacology Platelet Prevention Procedure Psychiatry Rheumatology Sarcoma Surgery Symptom Evaluation Vascular Page Marrow Index Anemia Aplastic Anemia Fanconi Macroglobulinemia Multiple Myeloma Myelofibrosis Polycythemia Epidemiology Elderly (mean age 68 years) Associated with certain occupational exposures Farmers Petroleum workers Woodworkers Leather workers Pathophysiology Malignant proliferation of Plasma Cells Plasmacytoma may also form solitary plasma cell tumor Symptoms and Signs Bone pain Osteolytic lesions Pathologic fractures Palpable swellings on accessible bones

83. Multiple Myeloma In Minnesota multiple myeloma Summary of Minnesota Cancer Statistics*, Gender Males are almost twice as likely as females to develop multiple myeloma. http://www.cancer.umn.edu/page/risk/multimy.html

Multiple Myeloma Summary of Minnesota Cancer Statistics* Incidence Mortality Median Age at Diagnosis (years) Lifetime Cancer Risk (per 1,000) Annual Rate (per 100,000) EAPC Annual Rate (per 100,000) EAPC Males Females Descriptive Epidemiology Risk Factors Incidence: Accounts for about 1% of all new cancers. Minnesota rate is slightly lower than national rate. There has been a 14.7% increase in national incidence from 1973 to 1995 and a slight decrease in incidence in Minnesota males from 1988 to 1996. Mortality: Mortality rates are about 80% of incidence rates, reflecting limited treatment success. Mortality rates have increased 36.6% in the U.S. from 1973 to 1995, with a similar trend seen in Minnesota. Gender: Males are almost twice as likely as females to develop multiple myeloma. Age: Risk increases with age with most cases occurring in the very elderly. Race: Greater incidence among blacks than whites; incidence lowest in Asians. SES: Higher SES associated with increased risk. Occupations/Chemicals: Farmers appear to be at increased risk for myeloma. Studies of pesticide use have yielded conflicting results but suggest some role. Exposure to paints, solvents, and benzene has been associated with myeloma but again the role is unclear. Numerous studies have associated myeloma with exposure to diesel/engine exhaust. Radiation: There is evidence that ionizing radiation is associated with myeloma; however, numerous studies have conflicting results.

84. Science News: Thalidomide Combats Myeloma Blood Cancer Although recently developed drugs have made many cancers survivable, multiple myeloma has resisted scientists best efforts. The http://articles.findarticles.com/p/articles/mi_m1200/is_21_156/ai_58225083

@import url(/css/us/style.css); @import url(/css/us/searchResult1.css); @import url(/css/us/articles.css); Advanced Search Home Help IN all publications this publication Reference Automotive Business Computing Entertainment Health News Reference Sports YOU ARE HERE Articles Science News Nov 20, 1999 Content provided in partnership with Print friendly Tell a friend Find subscription deals Thalidomide combats myeloma blood cancer Science News Nov 20, 1999 by N. Seppa Although recently developed drugs have made many cancers survivable, multiple myeloma has resisted scientists' best efforts. The likelihood of a patient withstanding this blood-cell cancer for 5 years remains less than 1 in 3as it has been for 3 decades. Now, the notorious antinausea drug thalidomide is demonstrating power that outclasses standard chemotherapy against myeloma. Banned in the 1960s for causing birth defects, thalidomide more recently has been shown to cure mouth ulcers and relieve complications of leprosy (SN: 11/11/95, p. 311; SN: 8/15/98, p. 111). Thalidomide prescribed in gradually increasing doses brought about improvements in 27 of 84 multiple myeloma patients in whom standard treatments had failed, scientists report in the Nov. 18 NEW ENGLAND JOURNAL OF MEDICINE.

85. Multiple Myeloma Papers Diseases. multiple myeloma Papers. Full Text Available. resource icon, multiple myeloma a personal account Nason, G. Lancet 363 2004 888. http://www.lrf.org.uk/en/1/dismmypapers.html

Diseases Multiple Myeloma Guidelines Further reading ... Medline Papers Other resources Trials Contact us Print this page ... Send to friend Diseases Multiple Myeloma Papers Full Text Available The following papers are all listed within the Medline database as being available as a free download (full text) from the web. If any of them are not so available, please do not contact the Fund as we do not control the content of Medline. Multiple Myeloma - a personal account Nason, G. Lancet Farnesyltransferase inhibitors and their role in the treatment of multiple myeloma Santucci, R., Mackley, P. A., Sebti, S., and Alsina, M. Cancer Control Thalidomide and its derivatives: new promise for multiple myeloma Weber, D. Cancer Control Trials of arsenic trioxide in multiple myeloma Hussein, M. A. Cancer Control Bortezomib (PS-341): a novel, first-in-class proteasome inhibitor for the treatment of multiple myeloma and other cancers Richardson, P. G., Hideshima, T., and Anderson, K. C. Cancer Control Multiple myeloma Anderson, K. C., Shaughnessy, J. D., Jr., Barlogie, B., Harousseau, J. L., and Roodman, G. D. Hematology (Am.Soc.Hematol Educ.Program.)

86. Multiple Myeloma - There's Hope! Perhaps you ve just heard the three most dreaded words You have cancer Worse yet, perhaps you were told you have multiple myeloma (MM) You may have had the http://www.cancerlynx.com/myeloma.html

May 19, 2003 Multiple Myeloma - There's Hope! Tom Courbat Those terrible first days Perhaps you've just heard the three most dreaded words (when used together) in the English language, "You have cancer". Worse yet, perhaps you were told you have Multiple Myeloma (MM), a disease you likely had never heard of, since it represents only 1% of the total cancer cases in the U.S., but 2% of the cancer deaths. You may have had the disease for several months (or years) but it escaped a proper diagnosis. Many doctors and oncologists have never treated an MM case, or have very few MM patients, thus it is fair to say that many will not be up on the latest treatments or clinical trials. They may not even be that knowledgeable about what factors are important to track related to MM. Multiple Myeloma is a malignant cancer of the plasma cell, which is a type of white blood cell found in bone marrow and many tissues of the body. Normal plasma cells fight infections, but malignant plasma cells lose this ability and crowd out other infection fighting cells. As the cancer grows, it destroys normal bone tissue, causing pain and crowding out normal cell production. It is considered a bone marrow/blood cancer and is closely related to leukemia and lymphoma. The old statistics indicated a typical lifespan following diagnosis of three to five years, although the new treatments are significantly extending this period. An acquaintance of mine lived 19 years with the disease, in relatively good health, so don't ever fall victim to "statistics" when it comes to Multiple Myeloma. For better or worse, you may be hit by a beer truck and die long before MM causes your demise!

87. Plasmacytoma, Multiple Myeloma 4-345 PPT multiple myeloma http://www.sbu.ac.uk/~dirt/museum/p4-345.html

Plasmacytoma, Multiple myeloma 4-345 To see Images first. Plasmacytoma amd multiple myeloma are both patterns of bone destruction, produced by an accumulation of plasma cells. The disease occurs in late middle age with a peak incidence at 60 years. Males are more likely to be affected, 2:1. The single mass of plasmacytoma is lytic and expands the bone with thinning of the cortex. The Multiple myeloma is multifocal and primarily medullary, in the bone marrow. There may be cortical erosion or scalloping. Since the Isotope bone scan does not record an abnormality, unless a reaction to a fracture, plain film surveys remain one way of assessing disease. The biochemistry reveals an accumulation of protein precursors to antibody production, the para-proteins. The accurate indicator of poor prognosis is impairment of renal function. Various anatomic expressions of pathology. view full image 112-3451 or review individual case plasmacytoma view full image 4411-3451 or review individual case Plasmacytoma 4411 view full image 454-3451 or review individual case Plasmacytoma view full image 418-3452 or review individual case Multiple myeloma a case of multiple myeloma ian@idmhome.demon.co.uk

88. U.S. Novartis Oncology - Multiple Myeloma Disease Introduction multiple myeloma Disease Introduction. Doctors keep improving treatments and continue to find ways to help people with multiple myeloma have better lives. http://www.us.novartisoncology.com/info/page/multiple-myeloma

For U.S. residents only. Non-U.S. residents Learn About Novartis Printer-friendly version E-mail this page U.S. Oncology Home Cancer Information Learn About Cancer Breast Cancer ... Gastrointestinal Stromal Tumors (GIST) Multiple Myeloma Disease Introduction Clinical Trials Our Products Reimbursement More Resources ... Healthcare Professionals Multiple Myeloma: Disease Introduction Cancer is made up of abnormal cells that multiply constantly People with multiple myeloma (also known as myeloma or plasma cell myeloma) now have more treatment choices and more hope  than ever before. Doctors keep improving treatments and continue to find ways to help people with multiple myeloma have better lives. We are always learning more about multiple myeloma, its prevention, detection, and treatment. This section of CancerSource will discuss all of these areas. What Is Multiple Myeloma? Multiple myeloma is cancer that begins in the plasma cells. Our bodies are made up of tiny building blocks called cells. Plasma cells make proteins that help our bodies fight disease. They are located in the soft part of our bones, called the bone marrow. Normal cells grow and multiply when the body needs them, and die out when the body does not need them. Cancer is made up of abnormal cells that grow whether they are needed or not.

89. :: IXth International Workshop On Multiple Myeloma :: abstract submission registration programmes. committees. general information scientific programme information exhibition. Poster Scientific http://myeloma2003.usal.es/

abstract submission registration programmes ... Accommodation Instructions for Authors: Poster Oral

90. Multiple Myeloma next up previous Next Case 1 Up Atlas of Hematology Previous Case 3. multiple myeloma. http://pathy.med.nagoya-u.ac.jp/atlas/doc/node78.html

Next: Case 1 Up: Atlas of Hematology Previous: Case 3 Multiple Myeloma Case 1 Case 2 Case 3 Case 4 ... [content] Nagoya University School of Medicine Department of Medicine The Branch Hospital Takuji Ichihashi, Tomoki Naoe Nagasaki University School of Medicine Department of Hematology Kazutaka Kuriyama Kyoto University College of Medical Technology Masataka Sasada Hamamatsu University School of Medicine Department of Medicine Three Ryuzo Ohno

91. Wisconsin Multiple Myeloma Support Group WISCONSIN multiple myeloma SUPPORT GROUP. We Want to Help. 01/03/2004. Welcome to the Wisconsin multiple myeloma Support Group. If http://www.madison.com/communities/multiplemyeloma/

Moderator WISCONSIN MULTIPLE MYELOMA SUPPORT GROUP Home About Us Contacts Events ... Wisconsin Multiple Myeloma Support Group We Want to Help Welcome to the Wisconsin Multiple Myeloma Support Group. If you, a loved one, or an acquaintance has been diagnosed with multiple myeloma we invite you to join us. In most cases, a newly diagnosed patient has never heard of multiple myeloma. To hear the words, "multiple myeloma", for the first time, and learn it is a noncurable cancer, is extremely frightening. Let us assure you, armed with the proper knowledge, good medical assistance, and the progress being made in the treatment of multiple myeloma, you have an excellent chance for many years with a good quality of life. Please check the links listed on the left side of this website for contacts, access to newsletters, and related links for more information. Browse articles: 'Providing an opportunity for multiple myeloma patients and their loved ones to exchange information, for mutual support, comfort, and friendship' madison.com

92. Pharmaceutical Research And Manufacturers Of America New Medicines in Development. multiple myeloma. Complete a new search ENMD 0995 none / none. Cancer, multiple myeloma. Celgene Warren, NJ. Phase I. http://www.phrma.org/newmedicines/newmedsdb/drugs.cfm?indicationcode=Multiple My

93. AllRefer Health - Multiple Myeloma (Malignant Plasmacytoma, Plasma Cell Dyscrasi multiple myeloma (Malignant Plasmacytoma, Plasma Cell Dyscrasia, Plasma Cell Myeloma, Plasmacytoma of Bone) information center covers causes, prevention http://health.allrefer.com/health/multiple-myeloma-info.html

AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia You are here : AllRefer.com Health Multiple Myeloma Multiple Myeloma Definition Treatment Expectations or Prognosis Complications ... Go To Main Page Alternate Names : Malignant Plasmacytoma, Plasma Cell Dyscrasia, Plasma Cell Myeloma, Plasmacytoma of Bone Definition Multiple myeloma is a cancer of the plasma cells in bone marrow. Cryoglobulinemia - of the Fingers Immune System Structures Antibodies Multiple myeloma is characterized by the excessive growth and malfunction of plasma cells in the bone marrow. The growth of these extra plasma cells interferes with the production of red blood cells, white blood cells, and platelets . This causes anemia , susceptibility to infection, and increased tendencies toward bleeding.

94. Treatment Of Multiple Myeloma, Mayo Clinic In Rochester, Minn. Treatment of multiple myeloma at Mayo Clinic in Rochester. (Synonyms Myeloma multiple myeloma is a cancer of plasma cells. Plasma cells http://www.mayoclinic.org/multiplemyeloma-rst/

Home About Mayo Clinic Contact Us Mayo Clinic Locations: Arizona Florida Minnesota Mayo Clinic ... Medical Services Multiple Myeloma Multiple Myeloma Treatment Symptoms and Diagnosis Appointments Clinical Trials ... Medical Services Treatment of Multiple Myeloma at Mayo Clinic in Rochester (Synonyms: Myeloma, Plasmacytoma, Monoclonal Gammopathy, Kahler's Disease) Mayo Clinic has one of the premier myeloma treatment groups in the world, with more than 60 years' experience treating multiple myeloma using a multidisciplinary approach that includes medications, experimental therapies, and diet and lifestyle management. Mayo has been a leader in the recognition of new treatments, prognostic factors, and a basic understanding of the biology of the disease. Multiple myeloma is a cancer of plasma cells. Plasma cells are found in bone marrow, the blood producing tissue that fills in spaces within bone. Plasma cells produce antibodies, substances that help the body fight infection. Usually plasma cells make up 1 to 2 percent of all cells in the bone marrow. In a person with multiple myeloma, however, abnormal plasma cells (or myeloma cells) multiply. The growth of myeloma cells results in reduced production of blood, which results in anemia. Fatigue is the most obvious

95. Mayo Clinic: Multiple Myeloma - Information And Treatment Options Mayo Clinic provides information on multiple myeloma cancer. Learn more Treatment of multiple myeloma at Mayo Clinic. (Synonyms Myeloma http://www.mayoclinic.org/multiplemyeloma/

Home About Mayo Clinic Contact Us Mayo Clinic Locations: Arizona Florida Minnesota Mayo Clinic ... Medical Services Multiple Myeloma Multiple Myeloma Overview Symptoms Treatment Options Appointments ... Medical Services Treatment of Multiple Myeloma at Mayo Clinic (Synonyms: Myeloma, Plasmacytoma, Monoclonal Gammopathy, Kahler's Disease) Mayo Clinic has one of the premier myeloma treatment groups in the world, with more than 60 years of experience treating multiple myeloma. Physicians use a multidisciplinary approach that includes medications, experimental therapies, and diet and lifestyle management. Mayo is a leader in research of new treatments, prognostic factors and a basic understanding of the biology of multiple myeloma. Mayo Clinic's integrated group practice allows rapid access to multiple specialists, as dictated by the specifics of the disease. Hematologists provide primary care for multiple myeloma patients and work closely with Mayo's bone marrow transplant teams, which have performed more than 2,000 transplants. Depending on the patient's needs and condition, consultations may also be arranged with other specialists such as an orthopedic or radiation oncologist. Diagnosis Special blood tests and X-rays may be done when myeloma is suspected, based on

96. Multiple Myeloma - Cancer Overview - Greenebaum Cancer Center multiple myeloma is the most common of a group of diseases called plasma cell neoplasms. multiple myeloma What Is multiple myeloma? http://www.umm.edu/cancer/overview/mult.html

UM Greenebaum Cancer Center Request An Appointment About UMGCC... Clinical Trials... ... UMGCC News Related Resources Within UMM Blood and Marrow Transplant Program Program for Hematologic Malignancies Hematologic Malignancies Treatment Team Multiple Myeloma Clinical Trials UM Greenebaum Cancer Center - Cancer Overviews IN THIS OVERVIEW... What Is Multiple Myeloma? Causes Symptoms Stages and Treatments ... Greenebaum Cancer Center Multiple Myeloma: What Is Multiple Myeloma? Multiple myeloma is the most common of a group of diseases called plasma cell neoplasms. Plasma cell neoplasms result when certain cells in the blood (called plasma cells) become cancerous. Plasma cells are made in the bone marrow by white blood cells called lymphocytes. The plasma cells make antibodies, which help fight infection in the body. Usually, bone marrow contains only about two percent plasma cells. But when a person has multiple myeloma, the body keeps making more and more abnormal plasma cells, called myeloma cells, and they make more and more antibodies. These extra cells do not help fight off infection; instead, they stop the body from making normal infection-fighting antibodies and crowd out normal cells. The cancer cells collect in the bone marrow and slowly destroy the bone. Myeloma cells also trigger the release of bone-weakening chemicals that lead to bone destruction and bone pain and can collect in the bone to make small tumors called plasmacytomas.

97. Origin Of Multiple Myeloma Found In Rare Stem Cell Media Contact Vanessa Wasta 410955-1287 wastava@jhmi.edu December 3, 2003 Origin of multiple myeloma Found in Rare Stem Cell Johns Hopkins Kimmel Cancer http://www.hopkinsmedicine.org/Press_releases/2003/12_03_03a.html

Print This Page Media Relations Staff Broadcast Services Publications ... The News Media Media Contact: Vanessa Wasta wastava@jhmi.edu December 3, 2003 Origin of Multiple Myeloma Found in Rare Stem Cell Johns Hopkins Kimmel Cancer Center scientists have identified the cell likely to be responsible for the development of multiple myeloma, a cancer of the bone marrow that destroys bone tissue. The research, published in Blood online, suggests that therapies designed for long-term cure of the disease should target this stem cell, which, unlike other cells, can copy itself and differentiate into one or more specialized cell types. In their studies to learn why multiple myeloma so often recurs following drug treatment, the investigators uncovered a rare stem cell , occurring in just one out of every 10,000 cells or less than one percent of all myeloma cells. Working with immune system B-cells, the Johns Hopkins team found that this stem cell gives rise to the malignant bone marrow plasma cells characterized by multiple myeloma. Current treatments target the malignant plasma cells but may not be effective on the errant multiple myeloma stem cells, allowing the cancer to recur. "Most therapies today are aimed at the cancer you can see, but to cure cancer you have to go after the cells responsible for the disease, similar to how we kill a weed by getting at its roots, not just the part above the ground," explains Richard Jones, M.D., professor and director of bone marrow transplant at the Johns Hopkins Kimmel Cancer Center. "If you cut off the flower and stem of a dandelion, it may look like it has died for a period of time, but the weed eventually will grow back. If you get the root, however, the weed does not grow back."

98. Anomalies MMUL multiple myeloma. Clinics and Pathology. Disease, multiple myeloma (MM) is a malignant plasma cell proliferation. Phenotype http://www.infobiogen.fr/services/chromcancer/Anomalies/MMUL.html

Atlas of Genetics and Cytogenetics in Oncology and Haematology Home Genes Leukemias Solid Tumours ... NA Multiple myeloma Clinics and Pathology Disease multiple myeloma (MM) is a malignant plasma cell proliferation Phenotype / cell stem origin phenotype of mature terminally differenciated B-cell, but also with CD56 expression, which is not found in normal plasma cells; CD38+ CD40+ Epidemiology multiple myeloma's annual incidence: 30/10 ; i.e. around 1% of malignancies in adults and 10ù of haematologic malignancies; mean age: 62 yrs Clinics patients may be asymptomatic at the time of diagnosis; bone pain; susceptibility to infections; renal failure; neurologic dysfunctions Pathology MM staging: stage I: tumour cell mass 10 g/dl; serum calcium ¾ 120 mg/l; no bone lesion; low monoclonal Ig rate (IgG < 50 g/l, IgA < 30 g/l, BJ urine 1.2 X 1012/m2; Hb 120 mg/l and/or advanced lytic bone lesions and/or high monoclonal Ig rate (IgG > 70 g/l, IgA > 50 g/l, BJ urine > 12 g/day) Treatment none before onset of symptoms; chemotherapy or BMT afterwards Prognosis evolution: multiple myeloma can evolve towards plasma cell leukemia , where plasma cell count is greater than 2000/ mm3; survival is highly variable (median is around 3 yrs); prognosis is according to the staging and other parameters (such as age, serum albumin, b2 microglobulin, C-reactive protein, and plasma cell labeling index); the karyotype is emerging as an important prognostic factor: median survival in case of a normal karyotype could be 4 yrs vs 1 yr in case of -13/del(13q) and/or 11q rearrangements (the chromosome anomalies with the worst prognostic impact)

99. Multiple Myeloma multiple myeloma. multiple myeloma. One in a series of booklets about leukaemia and related diseases directed at the public. multiple myeloma. http://omni.ac.uk/browse/mesh/C0026764L0026764.html

low graphics Multiple Myeloma broader: Paraproteinemias other: Ehlers-Danlos Syndrome Waldenstrom Macroglobulinemia Multiple myeloma One in a series of booklets about leukaemia and related diseases directed at the public. The document covers the causes, signs and symptoms, diagnosis, treatment, and prognosis of multiple myeloma (cancer which affects plasma cells in the bone marrow). Published on the Web by the Leukaemia Research Fund. Patient Education Handout [Publication Type] Multiple Myeloma Multiple Myeloma A collection of articles on multiple myeloma, from the May/June 1998 issue of Cancer Control, the journal of the Moffitt Cancer Center. Topics covered include biology of the transition of monoclonal gammopathy of undetermined significance to multiple myeloma, management of myeloma, interferon treatment, hematopoietic cell transplantation for multiple myeloma, overview of treatment, imaging in oncology, ten best readings on multiple myeloma and plasma cell dyscrasias, and a list of information for patients. CME accreditation is also available. Published on the Web by the Moffitt Cancer Center. Neoplasms Multiple Myeloma Medical Oncology Myeloma information centre ... Multiple myeloma This interactive tutorial on multiple myeloma, a type of cancer that affects white blood cells, has been produced by the Patient Education Institute, and is made available on the Web by the National Library of Medicine MEDLINEplus service. The tutorial provides background information on multiple myeloma and covers clinical signs and symptoms, causes, diagnosis, treatment, radiation, and chemotherapy. Viewing this tutorial requires Flash plug-in.

100. National Cancer Institute - Multiple Myeloma Treatment Date Last Modified 06/06/2003, health professional. multiple myeloma and Other Plasma Cell Neoplasms. multiple myeloma. Stage I multiple myeloma. http://www.nci.nih.gov/cancerinfo/pdq/treatment/myeloma/patient/

var bSearchBoxBool=false; window.onload+="MM_preloadImages('/images/nav_home_over.gif','/images/nav_cancer_topics_over.gif','/images/nav_clinical_trials_over.gif','/images/nav_cancer_statistics_over.gif','/images/nav_research_funding_over.gif','/images/nav_news_over.gif','/images/nav_about_over.gif');" Date Last Modified: Description Stage Explanation Treatment Option Overview Multiple Myeloma Isolated Plasmacytoma of Bone ... Print-friendly Quick Links Dictionary Funding Opportunities NCI Publications NCI Calendar NCI Highlights Some Men with Low PSAs Have Prostate Cancer Energy Balance Trans-HHS Cancer Health Disparities Report Past Highlights Description What are plasma cell neoplasms? What are plasma cell neoplasms? Plasma cell neoplasms are diseases in which certain cells in the blood (called plasma cells) become cancer. Plasma cells are made by white blood cells called lymphocytes. The plasma cells make antibodies, which fight infection and other harmful things in the body. When these cells become cancer, they may make too many antibodies and a substance called M-protein is found in the blood and urine. There are several types of plasma cell neoplasms. The most common type is called multiple myeloma. In multiple myeloma, cancerous plasma cells are found in the bone marrow. The bone marrow is the spongy tissue inside the large bones in the body. The bone marrow makes red blood cells (which carry oxygen and other materials to all tissues of the body), white blood cells (which fight infection), and platelets (which make the blood clot). The cancer cells can crowd out normal blood cells, causing anemia (too few red blood cells). The plasma cells also may cause the bone to break down. The plasma cells can collect in the bone to make small tumors called plasmacytomas.

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