1. New Page 1 Personal histories and a message board, alongside links to research. http://www.melorheostosis.com/

This page uses frames, but your browser doesn't support them.

2. Melorheostosis The etiology and incidence of melorheostosis is unknown. Bone dysplasia series. melorheostosis review and update. Can Assoc Radiol J. 1999 Oct;50(5)32430. http://www.stevensorenson.com/residents6/melorheostosis.htm

Home Up Cleidocranial dysostosis [ Melorheostosis ] Osteopathia striata Osteopetrosis Osteopoikilosis Proximal focal femoral deficiency ... Camurati-Engelmann disease The etiology and incidence of melorheostosis is unknown. It is often discovered as an incidental finding on radiographs acquired for other reasons. Other patients may have bone pain, limited range of motion, and joint fusion. The disease consists of cortical hyperostosis ("candle wax") in a dermatomal distribution. The location is usually diaphyseal. The process often crosses joints and may result in flexion contractures. The overlying skin may become thickened. REFERENCES Greenspan A, Azouz EM. Bone dysplasia series. Melorheostosis: review and update. Can Assoc Radiol J. 1999 Oct;50(5):324-30. Vanhoenacker FM, De Beuckeleer LH, Van Hul W, Balemans W, Tan GJ, Hill SC, De Schepper AM. Sclerosing bone dysplasias: genetic and radioclinical features. Eur Radiol. 2000;10(9):1423-33 BACK

3. Melorheostosis a CHORUS notecard document about melorheostosis Feedback. Search. melorheostosis. rare condition of cortical thickening of unknown etiology most commonly seen in the long http://chorus.rad.mcw.edu/doc/01061.html

CHORUS Collaborative Hypertext of Radiology Musculoskeletal system Feedback Search melorheostosis rare condition of cortical thickening of unknown etiology most commonly seen in the long bones 3-59 years sx: usu. pain of varying severity, occ. limited ROM, contracture insidious onset and chronic course xray findings: cortical sclerosis and thickening that may encroach on the medullary canal looks like wax flowing down a candle Brian Funaki, MD - 6 February 1995 Last updated 26 May 2004 Medical College of Wisconsin

4. Melorheostosis The suggested diagnosis is melorheostosis. Information on melorheostosis http//www.melorheostosis.com. Designed to share http://www.medlina.com/melorheostosis.htm

100 Hot Books 100 Hot CDs 100 Hot Videos 100 Hot DVDs ... Women's Health T he Web MEDLINA.com CDC WHO FDA NIH Search: All Products Books Magazines Popular Music Classical Music Video DVD Baby Electronics Software Outdoor Living Wireless Phones Keywords: CATEGORIES Home Up Marfan Syndrome Melorheostosis Meckel-Gruber Syndrome Microscopic Polyangiitis Machado Joseph Syndrome Mannosidosis Melorheostosis Electronic Journal of Hand Surgery - http://www.leeds.ac.uk A case study of a girl who had progressive and abnormal growth of the index finger of her left hand which was not enlarged at birth but grew steadily after birth. The suggested diagnosis is melorheostosis. Information on Melorheostosis - http://www.melorheostosis.com Designed to share research information as well as provide a location where others who are either suffering from this condition or attempting to treat it can share information and experiences. Melorheostosis.com - http://206.139.180.51 Links to research, articles, personal histories of patients and a discussion board. SUBCATEGORIES Up Search Now: info@medlina.com

5. Melorheostosis This 26 y/o male came to the ER complaining of increasing arm pain. An xray was performed. A selected image shown above demonstrates findings of melorheostosis. Bone dysplasia series. melorheostosis review and update. Can Assoc Radiol J 1999 http://home.earthlink.net/~radiologist/tf/120301.htm

This 26 y/o male came to the ER complaining of increasing arm pain. An x-ray was performed. A selected image shown above demonstrates findings of melorheostosis. Rotate the image (or your monitor) to the left (or your head to the right) and you will see the "flowing wax" appearance better. Vanhoenacker FM, De Beuckeleer LH, Van Hul W, Balemans W, Tan GJ, Hill SC, De Schepper AM. Sclerosing bone dysplasias: genetic and radioclinical features. Eur Radiol 2000;10(9):1423-33 PMID:10997431 Greenspan A, Azouz EM. Bone dysplasia series. Melorheostosis: review and update. Can Assoc Radiol J 1999 Oct;50(5):324-30 PMID:10555508 Rozencwaig R, Wilson MR, McFarland GB Jr. Melorheostosis. Am J Orthop 1997 Feb;26(2):83-9 PMID:9040882 Azuma H, Sakada T, Tanabe H, Handa M. Melorheostosis of the hand: a report of two cases. J Hand Surg [Am] 1992 Nov;17(6):1076-8 PMID:1430941 Williams JW, Monaghan D, Barrington NA. Cranio-facial melorheostosis: case report and review of the literature. Br J Radiol 1991 Jan;64(757):60-2 PMID:1998841 Perlman MD. Melorheostosis: a case report and literature review. J Foot Surg 1990 Jul-Aug;29(4):353-6 PMID:2229911

6. Bonetumor.org - The Web's Most Comprehensive Bone Tumor Resource Isolated cases of malignancy have been reported in association with melorheostosis, one osteosarcoma and one malignant fibrous histiocytoma. http://bonetumor.org/tumors/pages/page157melor.htm

Meloreostosis, Leri's disease, flowing periosteal hyperostosis This disease was described by Leri and Joanny in 1922. It is a rare, non-hereditary lesion that affects both sexes. It is usually apparent in early childhood and even in the first few days of life. About 50% of persons affected will develop the symptoms by 20 years of age. The classic radiographic appearance is that of sclerotic lesions of bones that look like wax dripping down the side of a candle. the name is derived from the greek melos "limb" and rhein "to flow". With an estimated incidence of 0.9 cases per million persons, it can be calculated that there are approximately 1,000,000 to 1,500,000 persons with meloreostosis currently alive. However, only about 300 cases have been reported in the literature. Patients with meloreostosis may have associated cutaneous and soft tissue lesions such as vascular malformations, neurofibromatosis, hemangioma, arterial aneurysms, linear scleroderma, tuberous sclerosis, hemangiomas, and focal subcutaneous fibrosis. Adults generally complain of pain, joint stiffness, and progressive deformity. In children the condition affects mainly the bones of the extremities and pelvis, and may result in limb length inequality, deformity, or joint contractures. Joint contractures may be accompanied by extraosseous bone formation.

7. Melorheostosis Other diseases with which melorheostosis has been associated are listed in Table of Osteopoikilosis, Osteopathia striata, and melorheostosis; this phenomenon is termed mixed http://www.amersham-health.com/medcyclopaedia/Volume III 1/MELORHEOSTOSIS.asp

Amershamhealth.com Search for: Type a word or a phrase. All forms of the word are searchable. Browse entry words starting with: A B C D ... Other characters Melorheostosis, a rare bone disorder whose initial manifestations include swelling of joints, pain, and limitation of motion. Eventually profound muscle contractures, tendon and ligament shortening, and soft tissue involvement with severe growth disturbances may ensue. Scoliosis, joint contracture and foot deformities may be seen. Frequently the radiographic alterations are limited to a single limb, more often the lower extremity. Cortical hyperostosis having the appearance of bone excrescences extending along its length resembles candle wax flowing down the side of a lit candle ( Fig.1 ). This hyperostosis may reach the carpus and tarsus as well as the metacarpals, metatarsals or phalanges. In the carpal and tarsal areas, more discrete round foci may resemble the findings of osteopoikilosis, whereas in the flat bones, radiating sclerotic patches are seen. In addition, soft tissue calcification and ossification may result in complete ankylosis of the joint. Scintigraphy reveals areas of increased skeletal accumulation of radionuclide, and MR imaging is also of value in diagnosis. On MR images, bone and soft tissue lesions are of low signal intensity on all pulse sequences.

8. Melorheostosis - Information / Diagnosis / Treatment / Prevention home rare disorders melorheostosis melorheostosis. melorheostosis Personal histories and a message board, alongside links to research. http://www.healthcyclopedia.com/rare-disorders/melorheostosis.html

Home Health cyclopedia All Topics by Category The Good Health Search Engine Health Conditions A-Z Gurus ... rare disorders > melorheostosis Melorheostosis Information / Diagnosis / Treatment / Prevention External links (marked with an arrow ) open in a new window. This site is a web directory and does not offer medical advice. We cannot take responsibility for information found on listed sites. This Page Related Topics Medical Definition Health News Web Directory: Related Topics: Musculoskeletal Disorders Medical Definition: University of Newcastle-upon-Tyne Medical Dictionary: "melorheostosis" Health News: Search millions of published articles for news on Melorheostosis Modern Medicine Aging The Ardell Wellness Report HealthFacts Medical Post Medical Update Men's Health and the National Women's Health Report Note: Subscription required to access the full text of articles. Web Directory: Electronic Journal of Hand Surgery Short case study with photo and x-ray. Melorheostosis Personal histories and a message board, alongside links to research. Notes: Healthcyclopedia presents health information in the form of websites and articles that encompass conventional medicine and alternative treatments Under no circumstances can it recommend or endorse a specific drug or therapy or treatment.

9. Melorheostosis Information Diseases Database melorheostosis Candle bones disease Candle wax disease, Disease Database Information http://www.diseasesdatabase.com/sieve/item1.asp?glngUserChoice=29229

10. Melorheostosis melorheostosis,. Print this article, a sequences. Other diseases with which melorheostosis has been associated are listed in Table 1. http://www.amershamhealth.com/medcyclopaedia/medical/Volume III 1/MELORHEOSTOSIS

Amershamhealth.com Search for: Type a word or a phrase. All forms of the word are searchable. Browse entry words starting with: A B C D ... Other characters Melorheostosis, a rare bone disorder whose initial manifestations include swelling of joints, pain, and limitation of motion. Eventually profound muscle contractures, tendon and ligament shortening, and soft tissue involvement with severe growth disturbances may ensue. Scoliosis, joint contracture and foot deformities may be seen. Frequently the radiographic alterations are limited to a single limb, more often the lower extremity. Cortical hyperostosis having the appearance of bone excrescences extending along its length resembles candle wax flowing down the side of a lit candle ( Fig.1 ). This hyperostosis may reach the carpus and tarsus as well as the metacarpals, metatarsals or phalanges. In the carpal and tarsal areas, more discrete round foci may resemble the findings of osteopoikilosis, whereas in the flat bones, radiating sclerotic patches are seen. In addition, soft tissue calcification and ossification may result in complete ankylosis of the joint. Scintigraphy reveals areas of increased skeletal accumulation of radionuclide, and MR imaging is also of value in diagnosis. On MR images, bone and soft tissue lesions are of low signal intensity on all pulse sequences.

11. Uhrad.com - Musculoskeletal Imaging Teaching Files uhrad.com Musculoskeletal Imaging Teaching Files. Case Forty Three - melorheostosis. Click On Images for Enlarged View Clinical History Patient presents with lower extremity pain and swelling. http://www.uhrad.com/msiarc/msi043.htm

uhrad.com - Musculoskeletal Imaging Teaching Files Case Forty Three - Melorheostosis Click On Images for Enlarged View Clinical History: Patient presents with lower extremity pain and swelling. Findings: Images #1 and 2 are plain films of the tibia demonstrating peripherally located hyperostosis producing a wavy sclerotic bony contour along the tibial diaphysis. There are similar findings involving the first metatarsal as well as the navicular and first cuneiform bone. In addition, there are soft tissue calcifications adjacent to the navicular and cuneiform. Diagnosis: Melorheostosis. Discussion: Melorheostosis is a rare disorder of bone which generally presents in early childhood. There are no known hereditary factors. The initial clinical presentation includes diffuse joint pain as well as swelling with associated limitation of motion. Other potential complications include muscle contractures as well as soft tissue involvement including calcifications. More severe cases will demonstrate growth disturbance which may lead to scoliosis, contractures, and deformities which may be severe. Radiologic manifestations are most commonly limited to a single limb, although multiple limbs may on occasion be involved. Melorheostosis most commonly involves the lower extremity, and is rarely see in the skull, facial bones, and ribs. The findings most commonly consist of osseous excrescences extending along the length of a bone simulating the appearance of "candle wax" dripping down the side of a candle. In the carpal and tarsal bones, there may be more discrete rounded regions of bony sclerosis as well as adjacent soft tissue calcifications. Nucleide scintigraphy cases of melorheostosis demonstrate a region of increased nucleide uptake. MR imaging demonstrate regions of decreased signal intensity on all pulse sequences.

12. Melorheostosis melorheostosis,. Print this article, nonhereditary condition ankylosis. GL. The Encyclopaedia of Medical Imaging Volume VII. melorheostosis, Fig. 1. http://www.amershamhealth.com/medcyclopaedia/medical/Volume VII/MELORHEOSTOSIS.A

Amershamhealth.com Search for: Type a word or a phrase. All forms of the word are searchable. Browse entry words starting with: A B C D ... Other characters Melorheostosis, nonhereditary condition of unknown aetiology usually confined to one limb, most commonly the leg, and usually involving at least 2 bones in a dermatomal distribution. Clinically the limb is stiff and painful, there may be thickening of the overlying skin and soft tissue contractures and fibrosis. Radiographs show dense cortical hyperostosis along long bones with a "dripping candlewax" appearance which may appear to flow from one bone to the next ( Fig.1 ). In a child the hyperostosis appears predominantly endosteal as opposed to an adult in whom it is usually more dramatic and causes an increase in the width of the bone. Epiphyses, carpal or tarsal bones tend to show more discrete rounded sclerotic foci (similar to osteopoikolosis) and flat bones may show radiating sclerotic patches. Radiographs may also show soft tissue calcification or ossification and joint ankylosis. GL The Encyclopaedia of Medical Imaging Volume VII Melorheostosis, Fig. 1

13. Bonetumor.org - The Web's Most Comprehensive Bone Tumor Resource Malignant fibrous histio. melorheostosis. Metastatic cancer menu. Multiple myeloma http://www.bonetumor.org/tumors/pages/page157.html

Sclerosing Bone Disorders Sclerosing bone disorders (Osteopathia striata, osteopoikilosis, and meloreostosis, Leri's disease, flowing periosteal hyperostosis) Osteopathia striata (Voorhoeve's disease) is a benign, usually painless disorder characterized by longitudinal dense striations in affected bones. In meloreostosis, there is thickening of the endosteal and periosteal bone that has been likened to "candle dripping". Multiple punctate or rounded small bone islands characterize Osteopoikilosis. Mixed sclerosing bone disorder refers to patients who have manifestations of two or three of these patterns together. Meloreostosis, Leri's disease, flowing periosteal hyperostosis (click on the link to view a full page on this disorder) Osteopoikilosis, spotted bones (click on the link to viw a full page on his disorder) Other rare hereditary and non-hereditary bone disorders marked by sclerosis or longitudinal dense striations in affected bones have been described that may have radiological similarities to the disorders described above. Sources: Bullough and Invigorita, Atlas of Orthopaedic Pathology, 1

14. Uhrad.com - Musculoskeletal Imaging Teaching Files uhrad.com Musculoskeletal Imaging Teaching Files. Case Fourteen - melorheostosis. No evidence of internal derangement was seen. Diagnosis melorheostosis. http://www.uhrad.com/msiarc/msi014.htm

uhrad.com - Musculoskeletal Imaging Teaching Files Case Fourteen - Melorheostosis Click on Images for Enlarged View Clinical History: Knee pain. Rule out internal derangement. Findings: Coronal T1 and sagittal T2 images of the knee show prominent linear areas of persistently very low signal intensity involving the fibula, tibia, femur, and patella. Some are centrally located within the medullary canal while others are clearly cortically based. No evidence of internal derangement was seen. Diagnosis: : Melorheostosis. Discussion: Melorheostosis is an uncommon bone disorder which often presents in children or young adults as extremity pain with limited range of motion. The symptoms may be progressive. In general, children are more severely affected and may develop muscle contractures and ligament and tendon shortening. It may be incidentally discovered in asymptomatic adults. Associated disorders have been reported; these include overlying linear scleroderma, osteopoikilosis, osteopathia striata, neurofibromatosis, tuberous sclerosis, vascular lesions, and hypophosphatemic rickets. The typical distribution is sclerotomal in one or more bones of an extremity. The axial skeleton can also be involved, however, either separately or in conjunction with extremity findings.

15. Uhrad.com - Musculoskeletal Imaging Teaching Files uhrad.com Musculoskeletal Imaging Teaching Files. Case Thirty Four - melorheostosis. Diagnosis melorheostosis. Discussion melorheostosis http://www.uhrad.com/msiarc/msi034.htm

uhrad.com - Musculoskeletal Imaging Teaching Files Case Thirty Four - Melorheostosis Click On Images for Enlarged View Clinical History: None. Findings: Diagnosis: Melorheostosis. Discussion: Melorheostosis was first described by Leri and Joanny in 1922. It typically presents in early childhood. It is equally prevalent in males and females. It is not hereditary. Affected individuals have a normal lifespan. Patients typically present with intermittent joint swelling and pain. Pain and limitation of motion is more typical in adults rather than children. Patients may experience muscle contractures and ligament and tendon shortening. Occasionally limb length discrepancies may be present. A variety of skin changes associated with this condition have been described. These include: tense erythematous, shiny skin; anomalous pigmentation; induration; edema; muscle atrophy; and linear scleroderma. Skin changes may precede osseous findings. This disorder can, on occasion, result in significant deformity. Plain radiography typically demonstrates lesions which are confined to one limb. The upper extremity is more often affected than the lower extremity. Lesions can also affect the bones of the skull, face and clavicle. Within the long bones lesions are characterized as peripherally located hyperostosis. Lesions tend to have a "flowing" appearance and have been compared to a "candle dripping." Endosteal lesions may partially or completely obliterate the medullary cavity. In lesions of the carpal and tarsal bones the lesions tend to be more discrete and somewhat rounded which may appear similar to those seen in osteopoikilosis. In flat bone lesions may be localized, patchy and sclerotic. Soft tissue calcifications are not infrequent, especially in the para-articular regions. These calcifications may progress to joint ankylosis. On bone scintigraphy lesions can have an appearance similar to that seen in Paget’s disease.

16. Melorheostosis - Eurorad - Clinical Case 1304 - Student teaching files,radiology,melorheostosis,The patient presented with swelling and chronic pain of the forearm without any medical history.,melorheostosis,EAR,ECR http://www.eurorad.org/case.cfm?uid=1304

17. Chicken Or Egg Scenario - Which Came First? - Eurorad - Clinical Case 1356 - Res AP and lateral views of the left index finger and subsequently an AP view of the left hand were performed.,melorheostosis,EAR,ECR,elearning,elearning. http://www.eurorad.org/case.cfm?uid=1356

18. Disease Directory : Rare Disorders : Melorheostosis Conditions and Diseases melorheostosis Top Links - melorheostosis Web Site Links. CRANIOFACIAL melorheostosis – CASE REPORT - CRANIOFACIAL melorheostosis ? http://www.diseasedirectory.net/Rare_Disorders/Melorheostosis/default.aspx

Wednesday, June 02, 2004 Rare Disorders Agnosia Aicardi Syndrome Alstrom Syndrome ... Rare Disorders : Melorheostosis Conditions and Diseases - Melorheostosis Top Links - Melorheostosis Web Site Links. Melorheostosis.com - Links to research, articles, personal histories of patients and a discussion board. CRANIOFACIAL MELORHEOSTOSIS – CASE REPORT - CRANIOFACIAL MELORHEOSTOSIS ? CASE REPORT. Craniofacial melorheostosis is rare, with only 5 cases previously described in the English literature. Geometry.Net - Health_Conditions: Melorheostosis - melorheostosis. rare condition of cortical thickening of unknown etiology most commonly seen in the long bones: Case Forty Three - Melorheostosis. Geometry.Net - Health_Conditions: Melorheostosis - experiences. http://www.melorheostosis.com. New htm. Melorheostosis a CHORUS notecard document about melorheostosis melorheostosis. rare Linear melorheostotic scleroderma with hypertrichosis sine ... - Linear melorheostotic scleroderma with hypertrichosis sine melorheostosis. 2, Campbell C, Papademetriou T, Bonfiglio M. Melorheostosis. Melorheostosis - Disease Mannosidosis. Melorheostosis. Electronic Journal The suggested diagnosis is melorheostosis. Information on Melorheostosis - http

19. Disease Directory : Melorheostosis Disease Mannosidosis. melorheostosis....... Diseases Rare Disorders melorheostosis melorheostosis. Directory Listing. Title melorheostosis http://www.diseasedirectory.net/detailed/27478.aspx

Wednesday, June 02, 2004 Rare Disorders Agnosia Aicardi Syndrome Alstrom Syndrome ... Melorheostosis : Melorheostosis Directory Listing Title: Melorheostosis Description: Disease Mannosidosis. Melorheostosis. Electronic Journal The suggested diagnosis is melorheostosis. Information on Melorheostosis - http Date Added: 2/17/2004 4:09:23 PM URL: http://www.medlina.com/melorheostosis.htm

20. PERSONAL INFORMATION AND EXPERIENCE Personal Histories. Shared by melorheostosis Patients. Alice, Adult, 2/23/2001, Left arm and shoulder (melorheostosis and osteopoikilosis), Lansing, Michigan. http://206.139.180.51/PIF master.htm

Personal Histories Shared by Melorheostosis Patients The following information is shared by fellow m elorheostosis patients about their own personal experience in dealing with this rare condition. It is in no way intended as a recommendation of any particular treatment, surgery, therapy or course of action, nor as a substitute for the expertise and judgment of your physician or other health care professional. Name Child/Adult Date Submitted Area of Body Affected Location Maria Adult Right femur and right knee Philippines Kent Adult Left foot, ankle, leg and hip Loganville, GA Hunter (Donna, mother Child Left foot and left lower leg Milan, TN Sharon Adult Right hand, arm, shoulder and collar bone Lake Worth, FL Liz Adult Middle finger of right hand UK, Stourbridge, West Midlands Julie Adult Right hip, femur and knee Franklin, PA William Adult Left leg from hip to knee Hoffman Estates, IL Azizul Adult Left foot (ankle) Perlis, Malaysia Graham Adult Right hand and middle finger Reading, England

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Page 1     1-20 of 85    1  | 2  | 3  | 4  | 5  | Next 20