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         Megaloblastic Anemia:     more detail
  1. Nutritional Anemias: Scurvy, Pernicious Anemia, Iron Deficiency Anemia, Folate Deficiency, Megaloblastic Anemia
  2. The Megaloblastic Anemias by L.J. Davis, Alexander Brown, 1953
  3. Megaloblastic Anemia
  4. The Megaloblastic Anemias. Modern Medical Monographs 18 by M D, Victor Herbert, 1959
  5. Anemia: An entry from Thomson Gale's <i>Gale Encyclopedia of Science, 3rd ed.</i> by Larry Blaser, 2004
  6. HealthScouter Anemia: Symptoms of Anemia and Signs of Anemia: Anemia Patient Advocate (HealthScouter Anemia)
  7. Nutritional megaloblastic anemias (Diagnostic criteria) by John J Will, 1966
  8. Idiopathic chronic megaloblastic anemia in children (Acta paediatrica. Supplementum) by Olga Imerslund, 1959
  9. Megaloblastic anaemia by V. I Mathan, 1967
  10. Gale Encyclopedia of Alternative Medicine: Vitamin B<SUB>12</SUB> by Judith Turner, 2001-01-01
  11. The Megaloblastic Anaemias by I. Chanarin, 1991-01-15
  12. Folates and Cobalamines by J. A. Zittoun, 1989-09

81. Medical Encyclopedia
BACK, Back to main Health Information page, This picture shows large, dense, oversized, red blood cells (RBCs) that are seen in megaloblastic anemia.
http://www.medstarhealth.org/body.cfm?id=124&action=DisplayImage&xurl=/imagepage

82. Extenza - Thiamine-responsive Megaloblastic Anemia Syndrome (TRMA) With Cone-rod
Thiamineresponsive megaloblastic anemia syndrome (TRMA) with cone-rod dystrophy. Author(s) FM Meire 1 MM Van Genderen 2 K. Lemmens
http://www.extenza-eps.com/extenza/loadHTML?objectIDValue=2245&type=abstract

83. Vitamins Problem Set
A. methylmalonic aciduria B. homocystinuria C. megaloblastic anemia D. hypersegmented nuclei in leucocytes E. sensory neuropathy. Tutorial. megaloblastic anemia.
http://www.biology.arizona.edu/biochemistry/problem_sets/b12/08t.html
B /Folate Problem set
Question 8: B deficiency
Tutorial to help answer the question Abnormal findings in patients with a vitamin B deficiency may include:
A. methylmalonic aciduria
B. homocystinuria
C. megaloblastic anemia
D. hypersegmented nuclei in leucocytes
E. sensory neuropathy
Tutorial
The folate trap strikes again! B Uptake Animation PDF of Overview figure
ThIS file IS in Adobe Acrobat (PDF) format. The advantage the PDF version is that printing is of much better quality than printing directly from your web browser. If you have not installed and configured the Adobe Acrobat Reader you can download the FREE Acrobat Reader from the Adobe site. This module has now come full circle from the first question ñ lack of B traps folate in the N -methyl form. For the affected patient, this means that the functions of both B and folate are disrupted. To explain the symptoms: methylmalonic aciduria - This is perhaps the only real way to distinguish a B deficiency from a folate deficiency (biochemically, at least). The enzyme methylmalonyl CoA mutase requires B (but not folate) as a cofactor, so its reactant (methylmalonyl CoA) accumulates only in a B

84. Amnionless, Essential For Mouse Gastrulation, Is Mutated In Recessive Hereditary
no. 3 pp 426 429 Amnionless, essential for mouse gastrulation, is mutated in recessive hereditary megaloblastic anemia Stephan
http://www.nature.com/cgi-taf/DynaPage.taf?file=/ng/journal/v33/n3/abs/ng1098.ht

85. MIR Teaching File Case St002
If intrisic factor had not made a difference, this ratio would be close to 1. Discussion megaloblastic anemia may be due to folic acid or B12 deficiency.
http://gamma.wustl.edu/st002te178.html

86. Megablastic Anemia Panel
Tube Type. Test ID, MEGAN. Test Number, M566. SMS Browse, megaloblastic anemia Panel. CPT Code(s), 83918 x2, 82136 x2. Group/Individual Test, GROUP.
http://www.pathology.med.unc.edu/path/labs/test/m/megablast.htm
Megablastic Anemia Panel
Includes: Methylmalonic Acid, Methylcitric Acid, Cystathionine, Homocysteine
Back
Use your browser's "Back" button to return to the previous page Tube Type Test ID MEGAN Test Number SMS Browse Megaloblastic Anemia Panel CPT Code(s) Group/Individual Test GROUP Laboratory Core Referral Testing Tube Station Specimen Routine: 4 mL blood/Serum Separator Tube/Gold Top Micro: 2 microtainers/ 1.0 mL blood Availability Routine: Reference Laboratory: Sent to Univ. of Colorado Health Sciences Center via Mayo STAT: NA Turnaround Time 10-14 days Reference Range Normal: See separate report Comments
Return to Test Information Introduction Page

Back
Use your browser's "Back" button to return to the previous page

87. Women Alive, Spring 1999: Women And Anemia
Most of these types of anemia can be corrected by taking supplementation. megaloblastic anemia means that your red blood cells are large and pale.
http://www.thebody.com/wa/spring99/anemia.html
WOMEN ALIVE
Awareness Is Life - Involvement Is Power - Spring 1999
Strategies for Self-Advocacy
Women and Anemia
By Debra Johnson, NP, PA-C and Judith Currier, MD
Anemia can be a very common finding in HIV-infection. There may be many causes; low red blood counts, low vitamin B12 stores, iron deficiency, a thyroid that may not be functioning correctly, a lot of blood loss during menses, low hormone levels, an effect from medication or an infection that invades the bone marrow (parvo B19, MAC, or a deep fungal infection).
Risk Factor
As many as 70-80% of HIV-infected patients develop anemia at some time during the course of their infection. Several clinical studies have suggested that anemia is an independent risk for a decrease in survival in patients with HIV disease. It is not clear if anemia was the only cause of a decrease in survival or if it is a part of concomitant opportunistic illness such as Mycobacterium avium or cytomegalovirus disease. One study done at Johns Hopkins University School of Medicine found anemia to be a rather strong risk factor for dying in patients infected with HIV. Many times women become so accustomed to feeling fatigue that they may never report it when they see their clinician. Sometimes anemia is such a common finding, that clinicians may not realize the impact that it can have on a women's energy level.

88. HerbChina2000.com - Herbal Remedies - Megaloblastic Anemia
megaloblastic anemia, DESCRIPTION Deficiencies of vitamin B12 and folic acid are the most common causes of megaloblastic anemia. Other
http://www.herbchina2000.com/therapies/HBA.shtml
Home Megaloblastic anemia DESCRIPTION Megaloblastic anemia is a blood disorder characterized by anemia, with red blood cells that are larger than normal, usually resulting from a deficiency of folic acid or of vitamin B-12. Deficiencies of vitamin B-12 and folic acid are the most common causes of megaloblastic anemia. Other causes are leukemia, myelofibrosis, multiple myeloma, certain hereditary disorders, drugs that affect DNA synthesis such as chemotherapy agents (methotrexate), alcohol, and other causes. SYNONYMS Anemia - Megaloblastic SYMPTOMS
  • Loss of appetite Diarrhea Tingling and numbness of hands and feet Pale skin color Tiredness Headaches Sore mouth and tongue Change in skin color
HERBAL TREATMENT Herbal treatment designed to improve symptoms, correct imbalance and adjust immune system, prevent and treat later diseases and/or complications, and most importantly, to boost energy and strong body for better health and quality of life.

89. Anemia, Megaloblastic - Quest Diagnostics Patient Health Library
Anemia, Megaloblastic. In addition, certain antitumor or immunosuppressive drugs may also cause megaloblastic anemia. . Resources.
http://www.questdiagnostics.com/kbase/nord/nord423.htm
document.write(''); var hwPrint=1; var hwDocHWID="nord423"; var hwDocTitle="Anemia, Megaloblastic"; var hwRank="1"; var hwSectionHWID="nord423"; var hwSectionTitle=""; var hwSource="us6.0"; var hwProdCfgSerNo="wsh_html_059_c"; var hwDocType="NORD";
National Organization for Rare Disorders, Inc.
Anemia, Megaloblastic
Important
It is possible that the main title of the report is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Synonyms
  • Megaloblastic Anemia of Pregnancy Folic Acid Deficiency Anemia Folate Deficiency Anemia Vitamin B12 Deficiency Anemia Hypovitaminosis B12
Disorder Subdivisions
  • None
General Discussion
An anemia is a condition in which the number of red blood cells (RBC) or the amount of hemoglobin (the protein in red blood cells that carries oxygen throughout the body) is below normal. Megaloblastic Anemias (MGA) are rare blood disorders characterized by the presence of large, structurally and visually abnormal, immature red blood cells (megaloblasts). Decreased numbers and immaturity of white blood cells (leukocytes) and blood platelets (thrombocytes) may also occur.
Megaloblastic Anemias are usually caused by a deficiency or defective absorption of either vitamin B12 (cobalamin) or folic acid. As a result, they are also known as the vitamin deficiency anemias. In most cases, the fundamental flaws leading to the several forms of MGA caused by vitamin deficiencies are present at the time of birth and exist as a result of a genetic defect. In addition, certain antitumor or immunosuppressive drugs may also cause Megaloblastic Anemia.

90. PharmGKB: Anemia, Megaloblastic
Anemia, Megaloblastic. Alternate Names Anemias, Megaloblastic; megaloblastic anemia; megaloblastic anemias. PharmGKB Primary Data. Phenotype Data Sets None.
http://www.pharmgkb.org/do/serve?objId=PA443349&objCls=Disease

91. Discovery Health Anemia
Anemia due to vitamin B12 deficiency is called pernicious anemia. Lack of folic acid can also cause anemia, which is called megaloblastic anemia.
http://health.discovery.com/diseasesandcond/encyclopedia/3148.html

92. Loyola Univ. Health Sys. - Blood Disorders - Megaloblastic (Pernicious)
megaloblastic (Pernicious) anemia. megaloblastic (Pernicious) anemia. What is megaloblastic (Pernicious) anemia? megaloblastic (pernicious) anemia megaloblastic (pernicious) anemia is
http://www.lumc.edu/health/topics/blood/aneper.htm
You are here: Home Health Information Health Topics Blood Disorders Megaloblastic (Pernicious) Anemia What is Megaloblastic (Pernicious) Anemia?
Megaloblastic (pernicious) anemia is a rare disorder in which the body does not absorb enough vitamin B12 from the digestive tract, resulting in an inadequate amount of red blood cells (RBCs) produced. What Causes Megaloblastic (Pernicious) Anemia? What is Anemia? Anemia is a common blood disorder, which is caused when there is a drop in hemoglobin or hematocrit in the blood.
  • Hemoglobin is the part of blood that distributes oxygen from the lungs to tissues in the body. Hematocrit is the measurement of the percentage of red blood cells found in a specific volume of blood. Anemia is usually a symptom of a disease rather than a disease itself.

93. Hematopathology
This hypersegmented neutrophil is present along with macroovalocytes in a case of pernicious anemia. Compare the size of the RBC's to the lymphocyte at the lower left center.
http://www-medlib.med.utah.edu/WebPath/HEMEHTML/HEME083.html
This hypersegmented neutrophil is present along with macro-ovalocytes in a case of pernicious anemia. Compare the size of the RBC's to the lymphocyte at the lower left center.

94. Hematopathology
This hypersegmented neutrophil is present along with macroovalocytes in a case of pernicious anemia. Compare the size of the RBC s
http://medlib.med.utah.edu/WebPath/HEMEHTML/HEME083.html
This hypersegmented neutrophil is present along with macro-ovalocytes in a case of pernicious anemia. Compare the size of the RBC's to the lymphocyte at the lower left center.

95. Www.ohsu.edu/cliniweb/handouts/megalobl.html
Hematology and Medical Oncology at Oregon Health Science Current Hem Onc Physicians Staff Internal Pages. Division of Hematology Medical Oncology. The disease of cancer will be banished
http://www.ohsu.edu/cliniweb/handouts/megalobl.html

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