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         Malignant Atrophic Papulosis:     more detail

21. Dorlands Medical Dictionary
Degos disease, syndrome (De·gos disease, syndrome) (dschwagomacrz¢) RobertDegos, French dermatologist, born 1904 malignant atrophic papulosis.
http://www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspzQzpgzEzzSzppdocszSzuszS

22. Degos Patients Support Network Website | Forum For Professionals
A case of malignant atrophic papulosis successfully treated with nicotine patches. 2Drucker CR. malignant atrophic papulosis response to antiplatelet therapy.
http://www.degosdisease.com/forum/forpros/research/dermatology2003exert.htm
British Journal of Dermatology 2003 Excerpt
A case of malignant atrophic papulosis successfully treated with nicotine patches
SIR , Malignant atrophic papulosis (Degos' disease) is a rare disorder of unknown cause, which is characterized by thrombotic vasculopathy affecting the skin, gastrointestinal tract, central nervous system, and occasionally other organs. It is often lethal because of gastrointestinal involvement. The cutaneous lesions consist of characteristic papules with porcelain-white central atrophy and telangiectatic borders. Similar lesions are seen on the serosal surface of the gastrointestinal tract; perforation of the tract is the most frequent cause of death. Treatments that have been tried for this disorder include antiplatelet therapy (aspirin and dipyridamole), 1,2 fibrinolytic therapy (phenformin and ethyloestrenol), 3 anisoylated plasminogen streptokinase activator and urokinase. 4 However, there is no really satisfactory treatment. 4 We describe a woman with this disorder whose skin lesions and gastrointestinal symptoms were treated successfully with nicotine patches.
T.Kanekura

23. Degos Patients Support Network Website | Information | For Professionals
malignant atrophic papulosis (MAP), Papulosis Atrophicans Maligna (PAM ), Degosdisease, KohlmeierDegos disease Morbus Kohlmeier-Degos (MKD) an Overview.
http://www.degosdisease.com/information/forpros/diagnosing-degos/patientsovervie
See German translation Malignant Atrophic Papulosis (MAP),
Papulosis Atrophicans Maligna (PAM ),
Degos disease,
Kohlmeier-Degos disease
Morbus Kohlmeier-Degos (MKD) :
an Overview Prof. Dr. Ch. Christos Zouboulis,
Chairman of the Department of Dermatology at the University Medical Center Benjamin Franklin , Berlin , Germany . NB This paper is mainly intended to inform patients. Medical terms are used intentionally and then explained in brackets to help patients learn these concepts in order, for example, to understand doctors' reports and scientific literature. The text in italics contains very detailed knowledge and is mainly intended for physicians. Patients may wish to leave out these passages when reading this paper.
Introduction Papulosis atrophicans maligna/ malignant atrophic papulosis (MAP) is a rare disease which was first described by Kohlmeier in 1941 (1) and, in the same year, by Degos, who documented it as a separate entity (2). There have been 130 cases described in literature to date. Clinical Presentation It is the characteristic skin changes caused by MAP which are diagnostic indicators.

24. Malignant Atrophic Papulosis Of Degos
rare disorders message board. malignant atrophic papulosis of Degos. Re malignantatrophic papulosis of Degos Miguel González 075302 10/04/00 (0)
http://www.healthboards.com/rare-disorders/743.html
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25. Re: Malignant Atrophic Papulosis Of Degos
Re malignant atrophic papulosis of Degos. In Reply to malignant atrophic papulosisof Degos posted by Judith Calder on November 05, 1999 at 113326
http://www.healthboards.com/rare-disorders/1335.html
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26. Degos Disease
EPIDEMIOLOGY, CHARACTERISTICS. SYNONYMS, malignant atrophic papulosis KöhlmeierDegos disease. INCIDENCE, Rare. DISEASE ASSOCIATIONS, CHARACTERIZATION.
http://www.thedoctorsdoctor.com/diseases/degos_disease.htm
Background This rare disease is important because a skin biopsy may be the first clue to the diagnosis. Patients classically develop multiple skin papules that evolve to have a dimpled appearance with a porcelain white center. This is the clue to the underlying disease which can affect the gastrointestinal tract and central nervous system and may lead to death. The skin biopsy places the pathologist at the center of the diagnostic evaluation. OUTLINE Epidemiology Disease Associations Pathogenesis Laboratory/Radiologic/Other Diagnostic Testing ... Internet Links
EPIDEMIOLOGY CHARACTERISTICS SYNONYMS Malignant Atrophic Papulosis
Köhlmeier-Degos' disease INCIDENCE Rare DISEASE ASSOCIATIONS CHARACTERIZATION Familial cases Rare PATHOGENESIS CHARACTERIZATION Unknown-has been considered a vasculitis, mucinosis, or thrombotic disorder No circulating immune complexes, anti-endothelial cell antibodies, or anticardiolipin antibodies identified ENDOVASCULITIS Some consider a primary endothelial cell defect with secondary thrombosis leading to infarctive changes LUPUS VARIANT
Degos' Disease: A Distinctive Pattern of Disease, Chiefly of Lupus Erythematosus, And Not a Specific Disease per se.

27. Entrez PubMed
Click here to read malignant atrophic papulosis in an infant. We report a7month-old girl with malignant atrophic papulosis (Degos disease).
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstra

28. Entrez PubMed
malignant atrophic papulosis (Degos disease) clinical review. Aproposof a case Article in French Sibillat M, Avril MF, Charpentier
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstra

29. Dermatology ImageBase -Index
Cutaneous BCell 3; malignant atrophic papulosis; Malignant Melanoma1; Malignant Melanoma 2; Malignant Melanoma 3; Malignant Melanoma 4;
http://tray.dermatology.uiowa.edu/ImageIndex.html
Dermatology ImageBase Index Return to the Dept. of Dermatology Home Page Return to the Dermatology ImageBase Introduction
  • Acanthosis Nigricans 1
  • Acanthosis Nigricans 2
  • Accessory Nipples 1 ...
  • Xerosis 1
    Return to the Dept. of Dermatology Home Page Return to the Dermatology ImageBase Introduction
    Return to Dermatology's Home page.
    Return to the Univ. of Iowa Home Page
    May, 1995 The information on these pages may not be used or redistributed without written permission from the Department of Dermatology, College of Medicine, The University of Iowa. Last updated January 29, 2004
  • 30. Degos Disease - Quest Diagnostics Patient Health Library
    Synonyms. Degos Syndrome; DegosKohlmeier Disease; Kohlmeier-Degos Disease;malignant atrophic papulosis. Disorder Subdivisions. None. General Discussion.
    http://www.questdiagnostics.com/kbase/nord/nord991.htm
    document.write(''); var hwPrint=1; var hwDocHWID="nord991"; var hwDocTitle="Degos Disease"; var hwRank="1"; var hwSectionHWID="nord991"; var hwSectionTitle=""; var hwSource="us6.0"; var hwProdCfgSerNo="wsh_html_059_c"; var hwDocType="NORD";
    National Organization for Rare Disorders, Inc.
    Degos Disease
    Important
    It is possible that the main title of the report is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
    Synonyms
    • Degos Syndrome Degos-Kohlmeier Disease Kohlmeier-Degos Disease Malignant Atrophic Papulosis
    Disorder Subdivisions
    • None
    General Discussion
    Degos disease is a rare systemic disorder that affects small and medium sized arteries, causing them to become blocked (occlusive arteriopathy). Degos disease usually progresses through two stages. During the first stage, characteristic skin lesions appear that may last for a period of time ranging from weeks to years. The second stage of Degos disease is most frequently characterized by lesions in the small intestine, but other organs may also be affected. Major symptoms may include abdominal pain, diarrhea, and/or weight loss. Intestinal lesions may break through the wall of the bowel (perforation), a potentially life-threatening complication. The exact cause of Degos disease is unknown.
    Resources
    Digestive Disease National Coalition
    507 Capitol Court
    Suite 200
    Washington, DC 20002

    31. Definitions Of Genetic Disorders-M.
    noonan.htm Malignant Acanthosis acnig.htm Malignant Acanthosis Nigricans acnig.htmMalignant Astrocytoma astromal.htm malignant atrophic papulosis degos.htm
    http://www.icomm.ca/geneinfo/def-m.htm
    For Information on Workshops and Seminars for Special Needs Children click here The GAPS INDEX
    to Information on the Internet about Genetic Disorders and Birth Defects

    Genetic Information and Patient Services, Inc. (GAPS)
    HOME
    DISORDERS GLOSSARY
    Definitions of Genetic Disorders beginning with the letter M Click on the link next to the disorder to view its definition.
    MAA lenz.html
    Machado Disease josephs.htm
    Machado-Joseph Disease josephs.htm
    Macrencephaly megalen.htm
    Macrocephaly macroc.htm
    Macrocephaly Hemihypertrophy proteus.htm Macrocephaly with Multiple Lipomas and Hemangiomata brrs.htm Macrocephaly with Pseudopapilledema and Multiple Hemangiomata brrs.htm Macroglobulinemia waldenst.html Macroglossia macroglossia.htm Macroglossia-Omphalocele-Visceromegaly Syndrome bws.htm Macrostomia Ablepheron Syndrome ams.htm Macrothrombocytopenia Familial Bernard-Soulier Type bss.htm Macula Lutea degeneration macdeg.htm Macular Amyloidosis amylo.htm

    32. Blackwell Synergy - Cookie Absent
    (French). 2, Degos R. malignant atrophic papulosis. Br J Dermatol 1979; 100 2135. DegosSyndrome malignant atrophic papulosis. Sem Dermatol 1995; 14 99-105.
    http://www.blackwell-synergy.com/links/doi/10.1111/j.1365-4632.2004.02080.x/enha
     Home An Error Occurred Setting Your User Cookie A cookie is a small amount of information that a web site copies onto your hard drive. Synergy uses cookies to improve performance by remembering that you are logged in when you go from page to page. If the cookie cannot be set correctly, then Synergy cannot determine whether you are logged in and a new session will be created for each page you visit. This slows the system down. Therefore, you must accept the Synergy cookie to use the system. What Gets Stored in a Cookie? Synergy only stores a session ID in the cookie, no other information is captured. In general, only the information that you provide, or the choices you make while visiting a web site, can be stored in a cookie. For example, the site cannot determine your email name unless you choose to type it. Allowing a web site to create a cookie does not give that or any other site access to the rest of your computer, and only the site that created the cookie can read it. Please read our for more information about data collected on this site.

    33. Blackwell Synergy - Cookie Absent
    CASE REPORT. malignant atrophic papulosis in an infant. Summary. We reporta 7month-old girl with malignant atrophic papulosis (Degos disease).
    http://www.blackwell-synergy.com/links/doi/10.1046/j.1365-2133.2002.04677.x/abs/
     Home An Error Occurred Setting Your User Cookie A cookie is a small amount of information that a web site copies onto your hard drive. Synergy uses cookies to improve performance by remembering that you are logged in when you go from page to page. If the cookie cannot be set correctly, then Synergy cannot determine whether you are logged in and a new session will be created for each page you visit. This slows the system down. Therefore, you must accept the Synergy cookie to use the system. What Gets Stored in a Cookie? Synergy only stores a session ID in the cookie, no other information is captured. In general, only the information that you provide, or the choices you make while visiting a web site, can be stored in a cookie. For example, the site cannot determine your email name unless you choose to type it. Allowing a web site to create a cookie does not give that or any other site access to the rest of your computer, and only the site that created the cookie can read it. Please read our for more information about data collected on this site.

    34. Atrophic
    rhinitis), rhinitis chronica atrophicans (bull nose, porcine atrophic rhinitis),papulosis atrophicans maligna (malignant atrophic papulosis), nysesyge (bull
    http://www.websters-online-dictionary.org/definition/english/at/atrophic.html
    Philip M. Parker, INSEAD.
    Atrophic
    Definition: Atrophic
    Atrophic
    Adjective
    . Relating to or characterized by atrophy; "atrophic arthritis". Source: WordNet 1.7.1
    Crosswords: Atrophic
    Specialty definitions using "atrophic" Bordetella bronchiseptica bronchiseptica Pasteurella multocida Poikiloderma Congenitale ... Top
    Commercial Usage: Atrophic
    Domain Title
    Books
    • Chronic Atrophic Gastritis ( reference
    • Osseointegration and Autogenous Onlay Bone Grafts: Reconstruction of the Edentulous Atrophic Maxilla ( reference (more book examples)
    Source: compiled by the editor from various references ; see credits. Top
    Non-Fiction Usage: Atrophic
    Subject Topic Quote
    Health
    Dentures causing ulceration of the atrophic mucosa over the mandible can initiate ORN. Spontaneous ORN can also occur without any obvious injury to the irradiated mandible. ( references Source: compiled by the editor from ICON Group International, Inc. ; see credits. Top
    Usage Frequency: Atrophic
    Atrophic " is generally used as an adjective (general or positive) approximately 100.00% of the time. " Atrophic " is used about 75 times out of a sample of 100 million words spoken or written in English. Its rank is based on over 700,000 words used in the English language. Some parts-of-speech are not covered due to the samples used by the British National Corpus. (note: percents less than one-hundredth of one percent have been omitted)

    35. Disease Directory : Degos Disease,Degos Syndrome,Degos-Kohlmeier Disease,Kohlmei
    Degos Disease,Degos Syndrome,Degos-Kohlmeier Disease,Kohlmeier-DegosDisease,malignant atrophic papulosis,Degos Disease,Degos Syndrome,Degos...... Translate this page
    http://www.diseasedirectory.net/detailed/27298.aspx
    Wednesday, June 02, 2004 Rare Disorders
    Agnosia

    Aicardi Syndrome

    Alstrom Syndrome
    ... Degos : Degos Disease,Degos Syndrome,Degos-Kohlmeier Disease,Kohlmeier ...
    Directory Listing
    Title: Degos Disease,Degos Syndrome,Degos-Kohlmeier Disease,Kohlmeier ...
    Description: Degos Disease,Degos Syndrome,Degos-Kohlmeier Disease,Kohlmeier-Degos Disease,Malignant Atrophic Papulosis,Degos Disease,Degos Syndrome,Degos-Kohlmeier Disease
    Date Added: 2/17/2004 3:55:20 PM
    URL: http://www.icomm.ca/geneinfo/degos.htm

    36. JW Dermatology -- Sign In
    Summary and Comment. No Antiphospholipid or Anti Endothelial-CellAntibodies in malignant atrophic papulosis. Malignant atrophic
    http://dermatology.jwatch.org/cgi/content/full/1995/1201/10

    Physician-authored

    summaries and
    The New England
    Journal of Medicine

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    37. Disease, Medication, Symptom Etc Database Index : M Diseases Database
    Male infertility Male pattern baldness Male pseudohermaphroditism see Ambiguousgenitalia (male genotype) malignant atrophic papulosis see Degos disease
    http://www.diseasesdatabase.com/disease_index_m.asp
    Diseases Database Index Sponsors Contact ... Previous Page
    Disease, medication, symptom etc database index : M
    Search
    Machado-Joseph Azorean disease

    Machupo virus see Bolivian hemorrhagic fever
    MacLeod's syndrome

    Macroamylasaemia

    Macroamylase see Macroamylasaemia
    Macrocephaly see Megencephaly
    Macrocornea see Megalocornea
    Macrocytic red blood cell see Macrocytosis (erythrocyte)
    Macrocytosis (erythrocyte)

    Macroglossia
    Macrogyria see Pachygyria Macrolactams Macrolides Macromastia see Breast hypertrophy Macroorchidism see Testicular enlargement Macro-orchidism see Testicular enlargement Macrophage migration inhibitory factor Macrosomia Macrostomia ... Macrothrombocytosis Macular atrophy, Jadassohn type see Anetoderma Macular atrophy, Schweninger-Buzzi type see Anetoderma Macular hole Macular pucker see Epiretinal membrane Macular star see Hard retinal exudate Maculopapular rash Maculopathy Maculopathy, age related see Senile macular retinal degeneration Madelung-Launois-Bensaude syndrome see Benign symmetrical lipomatosis of Madelung Madelung's deformity Madura foot see Mycetoma Madurella mycetomi Maduromycosis see Mycetoma Mafenide Maffucci syndrome see Enchondromatosis Maggot infestation see Myiasis Magnesium hydroxide Magnesium levels low (plasma or serum) see Hypomagnesemia Magnesium levels raised (plasma or serum) see Hypermagnesaemia Magnesium oxide Magnesium salts Magnesium sulfate ... Mahaim-type preexcitation Maidenhair tree see Gingko biloba Mairungi see Khat Majewski syndrome see Short rib-polydactyly syndrome type 2 Major histocompatibility complex class 2 deficiency see Bare lymphocyte syndrome type 2 Major histocompatibility complex class I deficiency Major tranquilizers

    38. ILDS - ICD10
    I77.800 malignant atrophic papulosis of Degos. I77.800 Malignant atrophicpapulosis of Degos. I77.800 Papulosis, malignant atrophic.
    http://web.ilds.org/icd10_list.php?VIEW=1&START_CODE=I74.4&START_EXT=10

    39. Lasion EUrope-Table Of Contents
    Graftversus-host disease Henoch-Schönlein purpura Hereditary angioedema Lichenaureus Livedoid vasculitis malignant atrophic papulosis Papular urticaria
    http://sme.kpn.be/lasion/trillder.htm
    ILLUSTRATED DERMATOLOGY
    CLASSIFICATION BY THEME Epidermis: disorders of cell kinetics and differentiation
    Disorders of epidermal appendages and related disorders
    Epidermal and appendageal tumors
    Disorders of melanocytes
    Epidermal-Dermal inflammatory conditions of unknown etiology
    Inflammatory and neoplastic disorders of the dermis
    Lymphomas, pseudolymphomas, and related conditions
    Disorders of subcutaneous tissue
    Disorders of the mucocutaneous integument
    Cutaneous changes in disorders of altered reactivity Dermatitis Disorders due to physical factors Skin changes related to mobility Photomedicine Disorders due to drugs and chemical agents Cutaneous lesions in nutritional, metabolic, heritable diseases Cutaneous manifestations of hematologic disorders Cutaneous manifestations of gastrointestinal and renal disorders Cutaneous manifestations of multisystem diseases Cutaneous manifestations of disease in other organ systems Bacterial diseases with cutaneous involvement Fungal diseases with cutaneous involvement Rickettsial diseases Viral diseases Sexually transmitted diseases Infestations Definitions Bites and stings References 1. EPIDERMIS: DISORDERS OF CELL KINETICS AND DIFFERENTIATION

    40. Degos Disease.
    Degos disease, also known as malignant atrophic papulosis is a rare disorder. Degosdisease, also known as malignant atrophic papulosis is a rare disorder.
    http://www.betterhealth.vic.gov.au/bhcv2/bhcarticles.nsf/pages/Degos_disease?ope

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