101. Wilmer Eye Institute Macular Degeneration Center macular degeneration in the New Millennium You can order audiotapes ofthe patient conference! Information for Clinicians and Scientists. http://www.wilmer.jhu.edu/mdp/mdp.html

The Wilmer Institute is committed to helping patients with age-related macular degeneration (AMD) and other macular degenerative diseases, through laboratory and clinical research and by improving the lifestyle of patients who are currently afflicted with these diseases. This has led to the organization of the Macular Degeneration Center at the Wilmer Institute which provides a multidisciplinary approach in which scientists and clinicians with many different types of expertise, work together toward the common goal of developing new treatments for macular degenerations. In addition to helping patients with AMD in the future by developing new treatments, it is the goal of the Center to provide support right now through our newsletter, support groups, and patient oriented meetings. Letter From the Director Greetings from Morton Goldberg, Director of the Wilmer Eye Institute Information for Patients What is Macular Degeneration? Eye Structure and Terms Macular Degeneration Basic Research at Wilmer Macular Degeneration Clinical Research at Wilmer ... More Sites on the Web "Macular Degeneration in the New Millennium" You can order audiotapes of the patient conference!

102. Brian's Eye, A Personal Encounter With Macular Degeneration A patient s perspective of macular degeneration and how to cope with eye disease. Agerelatedmacular degeneration. and Choroidal Neo-Vascularization. http://www.brianseye.com/

^ ^ ^ New home for brianseye ^ ^ ^ Please note above address ^ ^ ^ Brian's Eye Story A Personal Encounter with Age-related Macular Degeneration and Choroidal Neo-Vascularization ( updated AMD Research information available ) The Christmas of 1995 will be one which I shall never forget. With all the normal hustle and bustle of pre-Christmas organizing we sometimes ignore what's going on inside our own bodies. Then comes the stark reality that something is wrong. That is what happened to me and I hope it never happens to you. In these next few pages I shall tell you about an eye disease that I developed and how I came to grips with it. I spent the better part of a month scouring the Internet for information relating to AMD and CNV in hopes of understanding what my future held. I have included numerous links to other AMD and Ophthalmology pages and I'll show you some really gross pictures of my own eyes if you like. If you know what to watch out for, you might be able to receive treatment before its too late. Knowledge is a powerful drug that soothes the soul but only if taken in the right quantity and used with the right attitude.

103. Ophthalmologist - Eye Doctor Jamaica Hillside Flushing Queens New York Specializing in comprehensive eye exams, contact lenses, glasses, glaucoma, cataracts, diabetic retinopathy, macular degeneration and other procedures. http://www.belredcenter.com/mainqu.htm

EYE CARE - EYE DOCTOR EYE EXAM FLUSHING, HILLSIDE, HOLLIS, BAYSIDE OPHTHALMOLOGIST in JAMAICA, QUEENS, NEWYORK specializing in comprehensive eye exams, contact lenses, glasses,glaucoma, cataracts,diabetic retinopathy,macular degeneration Telephone: WELCOME Home General information Eye examinations Contact Lenses ... Facelift Thank you for visiting our web site! We will provide you with information regarding your eye care. At our eye care center we have been providing Jamaica, Hillside, Flushing, Queens and the surrounding area with a wide array of ophthalmic services such as comprehensive eye examinations, replacement contact lenses and contact lens fitting, low vision evaluation, glaucoma care and laser treatment, cataract surgery, diabetic retinopathy evaluation and laser treatment, macular degeneration diagnosis and preventive measures, refractive surgery for nearsightedness, astigmatism and farsightedness (LASIK), ophthalmic second opinions. At our state of the art optical dispensary department we provide a wide array of designer frames, sun glasses and optical accessories for adults and children. Additionally, we offer specialty products including: sports glasses, diving glasses and magnifiers. We also offer quality craftsmanship with our own in-house optical lab. Please come in and browse our frame selections. Our goal is to provide professional, progressive state-of-the-art eyecare in a friendly and personalized atmosphere for the welfare of our patients. Dr. Peter Fleming and staff take as much time as necessary to address your questions and concerns

104. Age-Related Macular Degeneration: Status Of Research National Institutes of Health status of research of prevalence in the U.S. elder population and current research. http://www.nei.nih.gov/news/statements/varmus.htm

Health Funding News Laboratories ... Statements and Reports on Vision NEI Statement Department of Health and Human Services National Institutes of Health National Eye Institute Age-Related Macular Degeneration: Status of Research Harold Varmus, M.D. Director, NIH March, 1997 Table of Contents Topic Page Executive Summary Introduction Background Age-Related Macular Degeneration ... Conclusion The following document represents a 1997 report to Congress by the National Institutes of Health. For more current information on AMD, please visit the following links: Age-Related Macular Degeneration: Information for Patients Ongoing AMD Studies Supported by the NEI Age-Related Eye Disease Study (AREDS) Complications of Age-Related Macular Degeneration Prevention Trial (CAPT) Submacular Surgery Trials (SST) Executive Summary The Senate Appropriations Committee, in its report accompanying the fiscal year 1997 Appropriations Bill, has requested a report from the National Eye Institute (NEI). The Committee has urged the NEI to "accelerate and encourage research in age-related macular degeneration (AMD)," and has asked NEI to provide a status report on research and prospects for the future. AMD is a common eye disease of the macula, a tiny area in the retina that helps produce sharp, central vision required for "straight ahead" activities such as reading, sewing, and driving. A person with AMD loses this clear, central vision; in some cases, vision loss is rapid and dramatic. AMD is a leading cause of severe visual impairment and blindness in the United States. It is estimated that AMD already causes visual impairment in approximately 1.7 million of the 34 million Americans over age 65.

105. Ophthalmologist - Eye Doctor Millburn Short Hills Summit Springfield Union Orang Specializing in comprehensive eye exams, contact lenses, glasses, glaucoma, cataracts, diabetic retinopathy, macular degeneration and other procedures. http://www.belredcenter.com/mainsh.htm

EYE CARE - EYE DOCTOR EYE EXAM SUMMIT SPRINGFIELD UNION OPHTHALMOLOGIST in SHORT HILLS - MILLBURN NEW JERSEY specializing in comprehensive eye exams, contact lenses, glasses,glaucoma, cataracts,diabetic retinopathy,macular degeneration Telephone: WELCOME Home General information Eye examinations Contact Lenses ... Facelift Thank you for visiting our web site! We will provide you with information about your eye care. At our eye care center we have been providing Short Hills, Millburn, Summit, Springfield, Union, Orange, Maplewood, Chatham and the surrounding area with a wide array of ophthalmic services such as comprehensive eye examinations, replacement contact lenses and contact lens fitting, low vision evaluation, glaucoma care and laser treatment, cataract surgery, diabetic retinopathy evaluation and laser treatment, macular degeneration diagnosis and preventive measures, refractive surgery for nearsightedness, astigmatism and farsightedness (LASIK), ophthalmic second opinions. At our state of the art optical dispensary department we provide a wide array of designer frames, sun glasses and optical accessories for adults and children. Additionally, we offer specialty products including: sports glasses, diving glasses and magnifiers. We also offer quality craftsmanship with our own in-house optical lab. Please come in and browse our frame selections.

106. Hospital Practice: Macular Degeneration macular degeneration The Emerging Genetics RICHARD ALAN LEWIS JAMES R. LUPSKIBaylor College of Medicine Discovery of the gene responsible for a recessive http://www.hosppract.com/issues/2000/06/lewis.htm

Macular Degeneration: The Emerging Genetics RICHARD ALAN LEWIS JAMES R. LUPSKI Baylor College of Medicine Discovery of the gene responsible for a recessive, early-onset maculopathy has focused attention on a biomolecular pathway in which subtle metabolic flaws become toxic to irreplaceable retinal cells. The pathway's identification points toward specific ways of intervening. Among patients with age-related macular degeneration, carriers of single mutations in the same gene are proving to be remarkably common. Dr. Lewis is Professor of Ophthalmology, Pediatrics, Medicine, and Molecular and Human Genetics and Dr. Lupski is Cullen Professor of Molecular and Human Genetics, Professor of Pediatrics, and Director, Medical Scientist Training Program, Baylor College of Medicine, Houston. In the United States alone, age-related macular degeneration (AMD) affects at least 11 million people. Of the four major causes of vision loss in persons over age 50, it accounts for more cases than the other threecataract, glaucoma, and diabetic retinopathycombined. Apart from laser photocoagulation of the subretinal neovascularization characteristic of the disease's exudative, or wet, form, there is no known intervention. As long as the pathogenesis remains mysterious, a specific treatment seems unlikely to emerge. Our own efforts to trace the pathogenesis have been modeled on an approach now achieving success in complex human disorders ranging from breast and colon cancer to neurodegenerative illnesses such as Alzheimer's disease. Each disorder is scattered throughout the population, often with age-related occurrence. Each has, however, a clinical analogue with a similar or even indistinguishable phenotype except for an earlier onset and occurrence only in certain families, within which it exhibits an inheritance pattern suggestive of a single-gene disease. In such families, modern genetic research techniques may identify a disease-related gene. Identification of the protein that the gene encodes may then give access to upstream and downstream molecules delineating the biologic pathways in which the protein is involvedpathways whose malfunction produces the inherited disease and that may hold at least part of the explanation for the more common, apparently uninherited cases as well.

107. Macular Degeneration (AMD): Causes, Symptoms, Treatments - From The Cleveland Cl macular degeneration (AMD) Causes, Symptoms, Treatments From the ClevelandClinic. Age macular degeneration AMD Causes, Symptoms and Treatments. http://my.webmd.com/content/article/63/72004.htm?z=4051_00000_7001_to_13

108. Macular Degeneration Note All links within content go to MayoClinic.com. Diseases and Conditions.macular degeneration. From MayoClinic.com Special to CNN.com. Overview. http://www.cnn.com/HEALTH/library/DS/00284.html

International Edition MEMBER SERVICES The Web CNN.com Home Page World U.S. Weather ... Special Reports SERVICES Video E-mail Services CNNtoGO Contact Us SEARCH Web CNN.com In association with: INFORMATION CENTERS: Pick a category Health Centers Family Health Men's Health Women's Health Children's Health Seniors' Health Working Life Pain Management Condition Centers Immune System Allergy Alzheimer's Arthritis Respiratory System Cancer Endocrine System Digestive System Heart and Blood Infectious Disease Mental Health Note: All links within content go to MayoClinic.com Diseases and Conditions Macular degeneration From MayoClinic.com Special to CNN.com Overview Age-related macular degeneration is a chronic eye disease that occurs when tissue in the macula, the part of your retina that's responsible for central vision, deteriorates. The retina is the layer of tissue on the inside back wall of your eyeball. Degeneration of the macula results in blurred central vision or a blind spot in the center of your visual field. The first sign of macular degeneration may be a need for more light when you do close-up work. Fine newsprint may become harder to read and street signs more difficult to recognize. Eventually you may notice that when you're looking at an object, what should be a smooth, straight line appears distorted or crooked. Gray or blank spots may mask the center of your visual field. The condition may progress rapidly, leading to severe vision loss in one or both eyes.

109. Macular Degeneration Vision Simulator The macular degeneration Simulator is designed to help patients and their caregiversbetter understand the possible progression of agerelated macular http://www.visionsimulator.com/macular_degeneration/

What is macular degeneration? People with age-related macular degeneration lose their central vision because of damage to the macula, an area at the back of the eye that allows us to see fine details. Although central vision blurs or darkens, side vision is not affected. Eventually, activities like reading and driving become impossible. Macular degeneration is the leading cause of vision loss in seniors but usually does not result in total blindness. Most people with macular degeneration retain enough useful vision to live independently. What are dry stage and wet stage macular degeneration? In dry stage macular degeneration, the most common form of the disease, macular tissues thin and slowly lose function. Wet macular degeneration is caused by abnormal blood vessels that grow behind the macula. These blood vessels frequently leak, causing scar tissue to form. The wet stage of the disease is less common but usually more damaging than the dry stage. Left untreated, wet macular degeneration may rapidly worsen. In general, approximately 14% to 20% of cases of dry stage macular degeneration progress to wet stage disease. What are the symptoms of macular degeneration?

110. Macular Degeneration, UPMC | University Of Pittsburgh Medical Center, Pittsburgh Information about diagnosis, treatment options, and current research for maculardegeneration from the health care experts at UPMC. macular degeneration. http://eye.upmc.com/MacularDegeneration/

Home Macular Degeneration Macular degeneration is a chronic and progressive disorder that affects the central part of the retina and causes reduced ability to see. Macular degeneration causes a gradual loss of sharp, central vision. Read more Overview Diagnosis Treatment Options ... Contact UPMC Supplemental content provided by HealthGate Data Corp Terms and Conditions

111. The Age-Related Macular Degeneration Project - UAB Department Of Ophthalmology http://www.eyes.uab.edu/armdinfo/

112. The Duke Center For Macular Degeneration Information and resources about agerelated macular degeneration, the leading causeof central vision loss and blindness, and research and current treatments. http://www.dukeeye.org/amd/

Recent News New York Times: Summer Sun Can Put Older Eyes at Risk, Study Says New online audio information on macular degeneration CNN: Smoking Raises Risk of Blindness News and Observer: Retina Shift Restores Sight Macular Translocation Surgery : A treatment for recent vision loss from Age-Related Macular Degeneration New drug combats age-related blindness Vitamins combat age-related blindness NIH Launches NIHSeniorHealth.gov Duke University Eye Center ward0060@mc.duke.edu

113. Your Eye Doctors At The Manatee/Sarasota Eye Clinic And Laser Center Information on laser surgery and eye problems including cataracts, macular degeneration, glaucoma, LASIK, amblyopia and strabismus (lazy eye). Offices in Sarasota and Bradenton. http://www.youreyedoctors.com/

We are committed to providing our patients with the most advanced and highest quality eye care to enhance their way of life through improved vision. We strive to treat each patient with dignity, kindness and compassion, to understand their needs and to exceed their expectations. Our entire staff is dedicated to providing quality eye care services in a professional, caring environment. We have outstanding medical training and the most advanced equipment available. Our doctors and staff are committed to providing you with comprehensive, quality care for your eyes. This site will serve as a resource to our services and policies. If you should have any questions or concerns, please let us know The Manatee/Sarasota Eye Clinic provides on-line information for educational purposes only and it should not be construed as personal medical advice. This information is not intended to replace a consultation with an eye care professional. The Manatee/Sarasota Eye Clinic disclaims any and all liability for injury or other damages that could result from use of this information. If you do not see an animated picture above

114. Macular Degeneration (Age-Related Type) - Senior Health, Aging And Elder Care He MedicineNet Home Diseases Conditions AZ List Senior Health Home MacularDegeneration (AgeRelated Type). macular degeneration (Age-Related Type). http://www.medicinenet.com/Macular_Degeneration_Age-Related_Type/article.htm

MedicineNet Home Senior Health Home > Macular Degeneration (Age-Related Type) Advanced Search Printer-Friendly Format Add to Favorites Email to a Friend ... Next page Macular Degeneration (Age-Related Type) What is macular degeneration? Macular degeneration is a disease that affects central vision and leads to loss of vision. Although there are forms of macular degeneration that strike young people, the condition occurs most commonly in people who are over 60 years of age. This disorder is thus called age-related macular degeneration (AMD). Age-related macular degeneration was formerly called "senile macular degeneration." This term was misinterpreted by many senior citizens as an unflattering reference and it has been discarded. "Senile" has been replaced by "age-related." Does age-related macular degeneration cause blindness? As a general rule, no. Because only the center of a person's vision is usually affected, blindness rarely occurs from the disease. However, injury to the macula in the center of the retina can destroy the ability to see straight ahead clearly. Therefore, AMD can sometimes make it difficult to read, drive, or perform other daily activities that require fine central vision. What is the macula?

115. Treating Macular Degeneration By Dr. Gene Bruno From The Acupuncture Center Details on treatment and explanations of related terms. http://www.acudoctor.com

Home Macular Treatment Testimonials ... Contact Us Welcome to The Acupuncture Center Dr. Gene Bruno is the lead acupuncturist at the Acupuncture Center. He has been treating patients with Acupuncture and Oriental Medicine for over 30 years. Many of his patients are treated for internal diseases and musculo-skeletal problems. There are wide ranges of health challenges that respond to Acupuncture. Acupuncture is a part of Oriental Medicine, a complete medical system that also includes herbal medicine, massage, nutrition and exercise. For more than 3000 years many cultures have benefited from this method of treating and preventing illness. Today, Oriental Medicine is recognized worldwide. The World Health Organization has documented the effectiveness of acupuncture, and medical schools as well as research facilities in the US and Europe are currently teaching and researching the many uses of acupuncture. Medical communities throughout the world are currently using Oriental Medicine in their health care systems.( Learn More Macular Degeneration and Retinitis Pigmentosa are now being treated with acupuncture and the Microstim 100i. The new technology allows patients to treat themselves in their own homes. (

116. LUTEIN /MACULAR DEGENERATION Information Page, Revision 5/03 Information relating lutein to macular degeneration (AMD) risk reduction, literaturereferences, dietary intake, chemical structure, source of pills. http://www.pressenter.com/~generics/

THE LUTEIN - MACULAR DEGENERATION RISK REDUCTION PAGE .........................LUTEIN MOLECULE CLICK ON HIGHLIGHTED WORDS FOR FURTHER INFORMATION LUTEIN , (loo teen) n [LATIN luteum = egg yolk, from luteus = yellow]- a yellow pigment in the chemical family of carotenoids and found in egg yolks, vegetables, marigold flowers, alfalfa and to a lesser degree in many other plants. The original medical association of LUTEIN was as an isolate from the corpus luteum, a part of the ovaries, and hence its name, but important medical aspects are its presence in the macula of the eye where it is strongly implicated in maintaining eye health, and as a protective agent from heart disease. Humans do not synthesize lutein and depend entirely on dietary sources such as vegetables (and eggs) or supplement lutein pills PROPERTIES: CHEMICAL-Organic, carotenoid, biological anti-oxidant, PHYSICAL (in purified form)-yellow colored slightly hydroscopic crystalline solid FORMULA C H O STRUCTURE- see graphic above MOLECULAR WEIGHT 644 Lutein has in the past several years been the subject of many studies (see reference link below) associating it with risk reduction for failing eyesight due to Age-related Macular Degeneration or AMD, and therefore has generated significant interest. While the National Eye Institute adopts a "guarded evaluation" (see NEI link at bottom) of a Lutein/AMD risk association, a general conclusion from the studies available is that increased

117. Macular Degeneration And CRP - Eye Disorders Including Cataracts, Lasik Eye Surg MedicineNet Home EyeSight Home macular degeneration and CRP. AdvancedSearch. macular degeneration and CRP. It always is exciting http://www.medicinenet.com/script/main/art.asp?articlekey=30664

118. Macular Degeneration Help, Dr. Wilson Virtual office of Dr. Wilson, a macular degeneration Specialist. (Vandalia) http://www.drwilson.com/

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119. Age-Related Macular Degeneration: Update For Primary Care - May 15, 2000 - Ameri AFP May 15, 2000. Age-Related macular degeneration Update for Primary Care. TABLE1 Risk Factors for Age-Related macular degeneration. Risk factor, Comments. http://www.aafp.org/afp/20000515/3035.html

Advanced Search Age-Related Macular Degeneration: Update for Primary Care DONALD S. FONG, M.D., M.P.H., Southern California Permanente Medical Group, Baldwin Park, California, and University of California, Los Angeles, School of Medicine, Los Angeles, California Age-related macular degeneration is the leading cause of severe vision loss among the elderly. In this condition, central vision is lost, but peripheral vision almost always remains intact. Affected persons rarely require canes or guide dogs. The diagnosis of age-related macular degeneration is based on symptoms and ophthalmoscopic findings, and the disease can be classified into atrophic and exudative forms. The two currently proven treatments are laser photocoagulation and photodynamic therapy, but these measures are effective in only a small fraction of eyes with the exudative form of macular degeneration. Vision rehabilitation can help patients maximize their remaining vision and adapt so that they can perform activities of daily living. Families need encouragement in providing support and helping patients adjust to being partially sighted. (Am Fam Physician 2000;61:3035-42.) E lderly persons are concerned about losing independence and mobility. Studies have shown that loss of central visual acuity leads to a reduction of daily activities and mobility in the elderly.

120. Macular Degeneration macular degeneration. DESCRIPTION Hereditary Genetically, this type ofmacular degeneration is autosomal dominant or recessive. Other types http://www.tsbvi.edu/Education/anomalies/macular_degeneration.htm

MACULAR DEGENERATION DESCRIPTION: Hereditary and untreatable group of diseases which affect the macular area of the retina. When the disease affects the choriocappilaris, as in central areolar choroidal sclerosis, there is gradual loss of central vision in middle life. Genetically, this type of macular degeneration is autosomal dominant or recessive. Other types of macular degeneration affect the pigment epithelium. Stargardt-Behr disease is transmitted genetically as an autosomal recessive factor; it results in gradual deterioration of the pigment epithelium, which begins at different ages and progresses at different rates; rate and degree of visual loss varies from family to family. In Best's vitelliform macular degeneration (an autosomal dominant genetic pattern), changes are confined to the macula. Initially, it resembles a poached egg "sunny side up;" later, the "yolk" appears scrambled, and central vision is seriously decreased. (see also Scotomas TREATMENT: Untreatable.

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