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         Machado-joseph Disease:     more detail
  1. The Official Patient's Sourcebook on Machado-Joseph Disease: A Revised and Updated Directory for the Internet Age by Icon Health Publications, 2002-09
  2. Machado-Joseph disease
  3. Origins of a mutation: population genetics of Machado-Joseph disease in the Azores (Portugal).: An article from: Human Biology by Manuela Lima, Francine M. Mayer, et all 1998-12-01
  4. Machado-Joseph disease: An entry from Thomson Gale's <i>Gale Encyclopedia of Neurological Disorders</i> by Sandra Galeotti, 2005
  5. Prevalence, geographic distribution, and genealogical investigations of Machado-Joseph disease in the Azores (Portugal).: An article from: Human Biology by Manuela Lima, Francine Mayer, et all 1997-06-01
  6. Machado-Joseph disease (SuDoc HE 20.3520:M 18) by U.S. Dept of Health and Human Services, 2001

21. Machado-Joseph - Information / Diagnosis / Treatment / Prevention
International Joseph Disease Foundation Offers education, medical referrals, updates, and support to all individuals interested in machado-joseph disease.
http://www.healthcyclopedia.com/genetic-disorders/machado-joseph.html

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Related Topics: Neurological Disorders/Brain Diseases Neurological Disorders/Spinal Cord/Spinocerebellar Degenerations Medical Definition: University of Newcastle-upon-Tyne Medical Dictionary: "Machado-Joseph" Health News: Search millions of published articles for news on Machado-Joseph Modern Medicine Aging The Ardell Wellness Report HealthFacts Medical Post Medical Update Men's Health and the National Women's Health Report Note: Subscription required to access the full text of articles. Web Directory: International Joseph Disease Foundation Offers education, medical referrals, up-dates, and support to all individuals interested in Machado-Joseph Disease. Machado Joseph Disease Origins of the disease and the Jewish connection. Symptoms, diagnosis, ongoing rsearch information, and resources.

22. Machado-Joseph Disease
National Organization for Rare Disorders, Inc. machadojoseph disease. Three forms of machado-joseph disease are recognized Types MJD-I, MJD-II, and MJD-III.
http://www.bchealthguide.org/kbase/nord/nord110.htm
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National Organization for Rare Disorders, Inc.
Machado-Joseph Disease
Important
It is possible that the main title of the report is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Synonyms
  • Autosomal Dominant Spinocerebellar Degeneration Azorean Neurologic Disease Machado Disease Joseph Disease MJD Nigrospinodentatal Degeneration Striatonigral Degeneration, Autosomal Dominant Type Spinocerebellar Ataxia Type III (SCA 3)
Disorder Subdivisions
  • Machado-Joseph Disease Type I (MJD-I) Machado-Joseph Disease Type II (MJD-II) Machado-Joseph Disease Type III (MJD-III)
Related Disorders List
Information on the following diseases can be found in the Related Disorders section of this report:
  • Hallervorden-Spatz Disease Olivopontocerebellar Atrophy Progressive Supranuclear Palsy (PSP) Amyotrophic Lateral Sclerosis Friedreich's Ataxia Marie's Ataxia Parenchymatous Cortical Degeneration of the Cerebellum
General Discussion
Machado-Joseph Disease (MJD-III), also called spinocerebellar ataxia type III, is a rare, inherited, ataxia (lack of muscular control) affecting the central nervous system and characterized by the slow degeneration of particular areas of the brain called the hindbrain. Patients with MJD may eventually become crippled and/or paralyzed but their intellect remains intact. The onset of symptoms of MJD varies from early teens to late adulthood.

23. Machado-Joseph Disease
machadojoseph disease. adulthood. Three forms of machado-joseph disease are recognized Types MJD-I, MJD-II, and MJD-III. The differences
http://www.meritcare.com/hwdb/showTopic.asp?pd_hwid=nord110

24. Machado-Joseph Disease - General Practice Notebook
machadojoseph disease. Medical search. machado-joseph disease is an autosomal dominant neuromuscular degenerative disease.
http://www.gpnotebook.co.uk/medwebpage.cfm?ID=-234487767

25. Machado-Joseph Disease - General Practice Notebook
machadojoseph disease. machado-joseph disease is an autosomal dominant neuromuscular degenerative disease. The clinical features
http://www.gpnotebook.co.uk/cache/-234487767.htm
Machado-Joseph disease Machado-Joseph disease is an autosomal dominant neuromuscular degenerative disease. The clinical features are primarily cerebellar ataxia and ophthalmoplegia. Machado-Joseph disease is also termed spinocerebellar ataxia type 3.
Click here for more information...

26. Machado-Joseph Disease
Subject machadojoseph disease Topic Area Ataxia Forum The Neurology and Neurosurgery Forum Question Posted By Eleonora on Wednesday, July 26, 2000
http://www.medhelp.org/perl6/neuro/messages/30707a.html
Questions in The Neurology Forum are being answered by doctors from
The Cleveland Clinic , consistently ranked one of the best hospitals in America. Subject: Machado-Joseph Disease
Topic Area: Ataxia
Forum: The Neurology and Neurosurgery Forum
Question Posted By: Eleonora on Wednesday, July 26, 2000
I'm 42 years old and was diagnosed with type III Spino-cerebellar ataxia (MJD) through a DNA examination three years ago. I decided by myself do exercises, physiotherapy and phonoaudiology in order to help me keep walking, talking and swallowing as long as I can. My mother also had this disease, and she died with 54 years old. I have a symptom she never had, diplopia, and I could find nothing to relieve this up to now, and it seems to get worse. I have miopia too, so when things get too bad, I put a tag over the lens on the eye with which I see worse, so I see only one image. But it also makes my balance worse, and when I take it off, my diplopia seems also worse.Do you have any physiotherapy, exercice or medicine to indicate me?
Recently, I started having tremors on my hands, when at rest or doing light movements. When it is bothering me to sleep, I simply lay down on my hands, so I do not allow them to shake. What can I do for this (in a more effective way?)

27. Health In The XXI Century: A Vision Of The European Youth
machadojoseph disease. The research in Portugal MJD, a research project. Molecular TEXT. machado-joseph disease an ataxia without cure. Doroteia
http://www.cienciaviva.pt/healthXXI/PedroV_dmj/index.asp?lang=en

28. Dictionary Definition Of MACHADO-JOSEPH DISEASE
Dictionary definition of machadojoseph disease. Medical dictionary. Browse Dictionary by alphabet. 0 1 2 3 4 5 6 7 8 9 A B C D E F
http://www.dictionarybarn.com/MACHADOJOSEPH-DISEASE.php
Dictionary definition of MACHADO-JOSEPH DISEASE
Browse Dictionary by alphabet A B C D ... Z Top Words ma
Ma-huang

maa

maalin
...
macrodactyl

A progressive degenerative disease of the central nervous system occurring in portuguese-azorean families, having a variety of forms and inherited as an autosomal dominant trait. There are four major types: type I: with pyramidal and extrapyramidal deficits; type II: with cerebellar, pyramidal and extrapyramidal deficits; type III: with cerebellar deficits and distal sensorimotor neuropathy; type IV: with parkinsonism and distal sensory neuropathy. It was originally reported in two portuguese-azorean families in massachusettes (machado), then in another portuguese family (thomas), and later in a third family in california (joseph, who settled there in 1845). It has been reported also in japanese families.
Please select first two letters of word you are looking for MA MB MC MD ... MZ fiSearchFormMaxSetId='AX006027'; Top Words macrodactylia
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29. Brazilian Journal Of Genetics - Molecular Characteristics Of Machado-Joseph Dise
Molecular characteristics of machadojoseph disease mutation in 25 newly described Brazilian families. Genetic aspects of machado-joseph disease.
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-84551997000400026&l

30. Arquivos De Neuro-Psiquiatria -
machadojoseph disease VERSUS HEREDITARY SPASTIC PARAPLEGIA. KEY WORDS spinocerebellar ataxia, machado-joseph disease, hereditary spastic paraplegia.
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2001000500030&l

31. Machado-Joseph Disease - Causes, Symptoms & Treatment
machadojoseph disease Fact Book. Table of Contents What is machado-joseph disease? machado-joseph disease (MJD)-also called spinocerebellar
http://www.healthnewsflash.com/conditions/machado_joseph_disease.php
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Machado-Joseph Disease Fact Book
Table of Contents
What is Machado-Joseph Disease?
Machado-Joseph disease (MJD)-also called spinocerebellar ataxia type 3-is a rare hereditary ataxia. (Ataxia is a general term meaning lack of muscle control.) The disease is characterized by clumsiness and weakness in the arms and legs, spasticity, a staggering lurching gait easily mistaken for drunkenness, difficulty with speech and swallowing, involuntary eye movements, double vision, and frequent urination. Some patients have dystonia (sustained muscle contractions that cause twisting of the body and limbs, repetitive movements, abnormal postures, and/or rigidity) or symptoms similar to those of Parkinson's disease. Others have twitching of the face or tongue, or peculiar bulging eyes. The severity of the disease is related to the age of onset, with earlier onset associated with a more severe form of the disease. Symptoms can begin any time between early adolescence and about 70 years of age. MJD is also a progressive disease, meaning that symptoms get worse with time. Life expectancy ranges from the mid-thirties for those with severe forms of MJD to a normal life expectancy for those with mild forms. For those who die early from the disease, the cause of death is often aspiration pneumonia.

32. Machado-Joseph Disease
machado joseph disease. machadojoseph disease signs. constipation machado-joseph disease. piles machado-joseph disease. machado-joseph disease pain.
http://www.icongrouponline.com/health/Machado-Joseph_Disease.html
ICON Health Publications
Official Health Sourcebooks The Official Patient's Sourcebook
on
MACHADO-JOSEPH DISEASE

(Autosomal Dominant Spinocerebellar Degeneration; Azorean Neurologic Disease; Machado Disease; Machado-Joseph Disease; Nigrospinodentatal Degeneration; Spinocerebellar Ataxia Type III; Striatonigral Degeneration, Autosomal Dominant Type) Revised and Updated for the Internet Age P A P E R B A C K Paperback Book Paperback Book Order by phone: 800-843-2665 (within USA) 1-201-272-3651 (from outside USA) Paperback Book Shipped in 3 to 5 business days
E B O O K Electronic File * E-Book version sent via e-mail in 2 business days Electronic File *E-Book version sent via e-mail in 2 business days Pages Price $28.95(USD) ISBN Published Synopsis A comprehensive manual for anyone interested in self-directed research on Machado-Joseph Disease. Fully referenced with ample Internet listings and glossary. Related Conditions/Synonyms Autosomal Dominant Spinocerebellar Degeneration; Azorean Neurologic Disease; Machado Disease; Machado-Joseph Disease; Nigrospinodentatal Degeneration; Spinocerebellar Ataxia Type III; Striatonigral Degeneration, Autosomal Dominant Type Description Table of Contents Introduction Overview Organization Scope Moving Forward PART I: THE ESSENTIALS Chapter 1. The Essentials on Machado-Joseph Disease: Guidelines

33. Azorean Neurologic Disease
Introduction Overview Organization Scope Moving Forward PART I THE ESSENTIALS Chapter 1. The Essentials on machadojoseph disease Guidelines Overview What Is
http://www.icongrouponline.com/browse/Health/Azorean_Neurologic_Disease.html
ICON Group
Browse - Health Sourcebook covering Azorean Neurologic Disease
http://www.icongrouponline.com/Health/Machado-Joseph_Disease.html Title: The Official Patient's Sourcebook on Machado-Joseph Disease Date Published: Pages: ISBN: About the Author(s)/Editor(s) James N. Parker, M.D. Dr. James N. Parker received a B.S. in Psychobiology from University of California, Riverside and his M.D. from the University of California, San Diego. In addition to authoring numerous research publications, he has lectured at various academic institutions. Dr. Parker is the medical editor for the Official Patient’s Sourcebook series published by ICON Health Publications. Philip M. Parker, Ph.D. Philip M. Parker is the Eli Lilly Chair Professor of Innovation, Business and Society at INSEAD (Fontainebleau, France and Singapore). Dr. Parker has also been Professor at the University of California, San Diego and has taught courses at Harvard University, the Hong Kong University of Science and Technology, the Massachusetts Institute of Technology, Stanford University, and UCLA. Dr. Parker is the associate editor for the Official Patient’s Sourcebook series published by ICON Health Publications.

34. Health Library -
machadojoseph disease. Important It is possible that the main title of the report machado-joseph disease is not the name you expected.
http://yalenewhavenhealth.org/library/healthguide/IllnessConditions/topic.asp?hw

35. Rare Diseases Regarding Machado-joseph Disease
Topic Rare Diseases. Expertalbert de vries Date5/14/2003 Subjectregarding machadojoseph disease Question I am a writer who is looking for information.
http://experts.about.com/q/2973/2957828.htm

36. Machado-Joseph Disease At Diseasebooks.com
machadojoseph disease Disease Books machado-joseph disease. The Official Patient s Sourcebook on machado-joseph disease A Revised and Updated
http://diseasebooks.com/m/Machado_Joseph_Disease/
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37. Healthwise
Topic machadojoseph disease, Back to previous page. Three forms of machado-joseph disease are recognized Types MJD-I, MJD-II, and MJD-III.
http://www.stlukes-sf.org/health/healthinfo/index.cfm?section=healthinfo&page=ar

38. Machado-Joseph Disease Medical Wisdom
machadojoseph disease Information Page. Table of Contents (click to jump to sections). What is machado-joseph disease? Is there any treatment?
http://medicalwisdom.com/health/disorders/machado-joseph.htm
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Table of Contents (click to jump to sections)
What is Machado-Joseph Disease?
Is there any treatment?

What is the prognosis?

What research is being done?

What is Machado-Joseph Disease?
Is there any treatment?
MJD is incurable, but some symptoms of the disease can be treated. For those patients who show parkinsonian features, levodopa therapy can help for many years. Treatment with antispasmodic drugs, such as baclofen, can help reduce spasticity. Physiotherapy can help patients cope with disability associated with gait problems, and physical aids, such as walkers and wheelchairs, can assist the patient with everyday activities. Other problems, such as sleep disturbances, cramps, and urinary dysfunction, can be treated with medications and medical care. What is the prognosis? The severity of the disease is related to the age of onset, with earlier onset associated with a more severe form of the disease. Symptoms can begin any time between early adolescence and about 70 years of age. MJD is also a progressive disease, meaning that symptoms get worse with time. Life expectancy ranges from the mid-thirties for those with severe forms of MJD to a normal life expectancy for those with mild forms. For those who die early from the disease, the cause of death is often aspiration pneumonia. What research is being done?

39. PharmGKB: Machado-Joseph Disease
machadojoseph disease. Alternate Names Autosomal Dominant Striatonigral Degeneration; Azorean Disease; Azorean Disease (Machado
http://www.pharmgkb.org/do/serve?objId=PA446552&objCls=Disease

40. The Friends Of The Machado-Joseph Disease Nucleus
The Friends of the machadojoseph disease Nucleus Manitoba, Canada E-mail albri@idirect.com (Jose Alfredo Brites) 6/2000, Bron / Source http//www.internaf
http://www.ataxie.nl/organisaties/naam_organisatie/the_friends_of_the_machado-jo
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