101. Leukemia leukemia / Myelodysplasia. 15 October 2003, copyright (c) 20012003 PathologyOutlines.com, LLC. Home Page. Microgranular variant of promyelocytic leukemia. http://pathologyoutlines.com/leukemia.html

Leukemia / Myelodysplasia Home Page PRINTER FRIENDLY PAGE Bold and underlined topics are hypertext links Excludes: leukemic phase of lymphoma, myeloproliferative disorders, chronic leukemias Table of Contents-Leukemia / Myelodysplasia Primary references AML: general classification t(8;21), t(V;17), ... acute panmyelosis with myelofibrosis ALL: general classification cytogenetics with cytoplasmic granules ... biphenotypic Myelodysplastic syndromes: general classification cytogenetics refractory anemia ... MDS unclassified Myelodysplastic/myeloproliferative syndromes: general chronic myelomonocytic leukemia atypical chronic myeloid leukemia juvenile myelomonocytic leukemia ... other pediatric MDS Primary references top American Journal of Clinical Pathology (AJCP) , Jan1997 to Jan2002 American Journal of Surgical Pathology (AJSP) , Aug1979 to Feb 2003 Archives of Pathology and Laboratory Medicine (Archives) , Jan1997 to Jan2002 Human Pathology (Hum Path) , Jan1997 to Dec2001 Modern Pathology (Mod Path) , Jan1988 to Jan2003 Kjeldsberg, CR: Practical Diagnosis of Hematologic Disorders (3rd Edition); ASCP Press, 2000 Please refer to these primary references for more detailed discussions and photographs AML Acute myelogenous leukemia (AML) - general top Neoplastic proliferations of hematopoietic precursor cells, causing excessive myeloblasts and other immature myeloid cells

102. Alex's Place - Update On Alex's Fight Against Acute Mylogenous Leukemia Update on 3 1/2 year old Alexandra Martini's three year fight against pediatric Acute Mylogenous leukemia. http://www.alexupdate.com

Thursday April 8, 2004 Hi Everyone, Just a quick update to let you know that Alex had the LP (lumbar puncture) on Tuesday and the results came back yesterday. Zero leukemia blasts in her CNS! At this point it's possible that the seizure was caused by whatever respiratory virus all four of us currently have. It also appears that the seizure triggered the increase in her White Blood Count (WBC). As of Tuesday her WBC was back down to normal range. Because of the virus, Alex is going to miss school all of this week and next week is Easter break. As long as there are no further complications she'll return the school after the break. Thanks again to everyone for helping us through yet another crisis. Take care. Todd Saturday April 3, 2004 @ 10 pm Hi Everyone, We're out of the hospital! Alex had an MRI today and although the calcifications (scarring) from her prior radiation and chemo treatments remain, there was nothing there to cause alarm. The doctors feel that she will remain stable as long as she remains on Depakote, an anti-seizure medication. What this means is that Alex will more than likely have to take Depakote for the rest of her life to avoid future seizures. The doctors also didn't feel it was necessary to do the LP (lumbar puncture) before we left the hospital today. We should know by Monday when it will be scheduled for.

103. Alternative Natural Health - Breakthrough - A Powerful Natural Nutritional Remed Discusses how natural trace elements in the diet can prevent cancers, Arthritis, MS, leukemia and most autoimmune diseases. http://www.truehealth.org

IN A NUTSHELL SUPREME HEALTH POISON FREE AGRICULTURE STABLE CLIMATES ... COMMENTARY All of the above subjects, plus the cosmic law of Progressive Complexity, the driving force of all Life, growth and evolution, in a nutshell. The complete natural range of the 72 trace elements in a daily serving of seafood [our daily food has 8] gets rid of most 'incurable' diseases and many cancers. Re-establishing the complete natural range of the 72 trace elements in agricultural soils [instead of today's paltry 8] results in a rich, abundant, permanently sustainable, totally poison free and supremely healthy agriculture. The massive decimation of the Earth's forests - 80% are gone - is driving our climates to the bitter extremes of lifeless desert climates. Reforesting the Earth will re-establish a vibrantly healthy biosphere, and end the greenhouse effect Commentary on major issues of our Times and Lives based upon the fundamental driving forces of Life and our Biosphere. a powerful natural remedy for many cancers and 'incurable' diseases - Arthritis, MS, Leukemia, most autoimmune diseases ... - and there is nothing to buy, no product is involved, and all the info is free for personal use only -

104. Team In Training The leukemia Lymphoma Society s Team In Training ® is the world s largest endurance sports training program. Did you participate in a leukemia Cup Regatta? http://www.teamintraining.org/hm_tnt

Glossary Site Find on Map Email: Password: Remember Me Not Yet Registered? HOME ABOUT TEAM IN TRAINING The Mission and History ... National Teams To visit our national site, click below: HOME PATIENT SERVICES DISEASE INFORMATION HOW TO HELP ... CALENDAR is the world's largest endurance sports training program. The program provides training to run or walk a whole or half marathon or participate in a triathlon or century (100-mile) bike ride. By helping to raise funds for leukemia, lymphoma and myeloma research and patient services, you'll receive: Personalized fitness training by certified coaches for a period of four to five months Training clinics A supportive group of teammates Lodging and airfare to more than 60 accredited events in the United States and abroad, including , in San Francisco, CA, the Suzuki Rock ‘n' Roll Marathon , in San Diego, CA, and many others Contact us for more details or to find out about upcoming information meetings in your area. CALENDAR April 27, 2004 - October 24, 2004 Join Us for The Nike 26.2 San Francisco, CA

105. Acute Lymphocytic Leukemia, Basic This acute lymphocytic leukemia (ALL) basic overview covers ALL symptoms, diagnosis and treatment options including blood stem cell transplants. NMDP Home, http://www.marrow.org/MEDICAL/all.html

Home Medical Information Diseases Treatable By Stem Cell Transplant > Acute Lymphocytic Leukemia, basic Acute Lymphocytic Leukemia (ALL), basic Many articles on this Web site are written at two levels: The basic version is written at an introductory level and includes explanations of medical terminology. In the future, an advanced version will contain in-depth information written in the style of a medical journal. Jump to a Section: Symptoms and Diagnosis Chemotherapy Blood Stem Cell Transplant Two Types of Stem Cell Transplants: Autologous and Allogeneic Acute lymphocytic leukemia, also called acute lymphoblastic leukemia and acute lymphoid leukemia, is a common leukemia. About 4,000 new cases are diagnosed each year in the United States. Most cases of acute lymphocytic leukemia (ALL) occur in children under age 10, but it can appear in all age groups. ALL is an acute leukemia, which means it is a disease that gets worse quickly. ALL is not inherited. It is caused by a change in the cells in the bone marrow. In most cases, no one knows why this change occurs, but a few environmental factors are linked with ALL. These include high doses of radiation and exposure to toxins before birth or in early childhood. Symptoms and Diagnosis In a healthy person, the bone marrow makes the blood stem cells that turn into the white blood cells, red blood cells and platelets in the blood. An ALL patient's marrow makes too many blast cells (immature white blood cells). These blast cells should turn into the white blood cells called lymphocytes, but they do not. So many blast cells grow that the marrow does not have room to make the normal red blood cells, white blood cells and platelets. This causes these symptoms of ALL:

106. Acute Myelogenous Leukemia (AML), Basic Acute myelogenous leukemia symptoms, diagnosis and treatment options, including blood stem cell transplants. NMDP Home, Acute Myelogenous leukemia (AML), basic http://www.marrow.org/MEDICAL/aml.html

Home Medical Information Diseases Treatable By Stem Cell Transplant > Acute Myelogenous Leukemia (AML), basic Acute Myelogenous Leukemia (AML), basic Many articles on this Web site are written at two levels: The basic version is written at an introductory level and includes explanations of medical terminology. In the future, an advanced version will contain in-depth information written in the style of a medical journal. Jump to a Section: Acute Myelogenous Leukemia Symptoms and Diagnosis Chemotherapy Blood Stem Cell Transplant Two Types of Stem Cell Transplants: Autologous and Allogeneic Acute myelogenous leukemia (AML) is also known by several other names, including acute myeloblastic leukemia, acute myelocytic leukemia and acute nonlymphocytic leukemia. AML is not inherited or contagious. It develops when there is a defect in the immature cells in the bone marrow. The exact cause of AML is unknown, but some environmental factors are linked with AML, including exposure to radiation and benzene. AML occurs in all ages but more often in older adults. With more than 10,000 new cases diagnosed annually, AML is the more common type of acute leukemia in adults (the other type is acute lymphocytic leukemia Acute Myelogenous Leukemia Symptoms and Diagnosis Acute myelogenous leukemia (AML) symptoms result from the body not producing enough healthy blood cells. Healthy bone marrow makes stem cells that grow into the three types of blood cells: red blood cells, white blood cells and platelets. An AML patient's bone marrow makes too many blast cells (immature white blood cells). Normal blast cells turn into a type of white blood cell called granulocytes, but the leukemia blast cells do not. At the same time, the marrow cannot grow enough normal red blood cells, white blood cells and platelets.

107. CaringBridge.org - Kendrie Little Kendrie is a child who is fighting leukemia. Site includes her story, and pictures. http://www.caringbridge.org/ga/kendrie

about CaringBridge home page view guestbook view photos ... make a tribute donation This is Kendrie And her Anthem to Leukemia! Diagnosed with ALL in October, 2003, one month after her 4th birthday, Kendrie is a happy, giggly little girl who is a tomboy at heart. She loves playing outside, swimming, riding her bike, building forts, and says when she grows up, she wants to be "a boy". On occasion, though, we catch her playing with dolls (usually GI'Joes), so not all hope is lost yet! :) NEW PHOTOS ADDED TO THE PHOTO ALBUM APRIL 14, 2004 "Hit the Road, Jack!" our message to leukemia; "and don't ya come back no more!" FAQ RE ALL (how’s that for short and sweet?) Q. What, exactly, is leukemia? "Well, to be honest, it’s pretty much the biggest suck-fest our family has ever faced. Oh, you wanted the medical definition? Well, in that case, leukemia is cancer of the blood forming tissues that make up the bone marrow inside the large bones. The diseased bone marrow then floods the body with abnormal white cells. These cells do not perform the infection fighting functions of healthy, mature white cells. In addition, production of red cells, which carry oxygen, and platelets, which help prevent bleeding, is decreased. Around our house, in laymen’s terms, leukemia is “sick blood”." Q. Are there different types of leukemia?

108. Childrens Leukemia Research Association! Childrens leukemia Research Association! Describing National leukemia, children s leukemia, National leukemia Association and Team leukemia. http://www.childrensleukemia.org/

childhood leukemia,leukemia, cancer, myeloid leukemia, blood disorders, patient aid, children's leukemia, childhood diseases, children's leukemia research association, hematology, research grants, oncology, team leukemia, countdown to a cure, pediatric hematology, children's blood disorders, childhood blood disorders, diseases, leukemia patient aid program, leukemia research grant, Peter Wiernik, Janice Dutcher, George Marcoullis, marcoulis, wiernick, ducher, our lady of mercy , comprehensive cancer center, sti571, interferon, myelogenous, t cells, t-cells, donations, charitable donations, money goes to research, leukemia, lukemia Click Here for CLRA's "Countdown to a Cure!" Updates and Information... The Children's Leukemia Research Association's "T EAM L EUKEMIA " Medical Advisory Committee of the Children's Leukemia Research Association Janice P. Dutcher, MD Currently Professor of Medicine at New York Medical College and is Associate Director for Clinical Affairs at Our lady of Mercy Comprehensive Cancer Center, Bronx New York Peter H. Wiernik, MD

109. The Mark Forti Leukemia Fund WebSite Includes involvement history and fundraising information. http://www.markfortifund.com/

The Mark Forti Leukemia Fund WebSite Helping Kids With Cancer Leukemia Fund Cancer Kids Mark Forti Click here to enter http://24.60.113.94 namesdirect.com - Register your domain name

110. Curing Childhood Leukemia - Summary reproduce uncontrollably. This article describes the treatment developed for leukemia, a cancer of the blood and bone marrow. In http://www.beyonddiscovery.org/content/view.asp?I=285

111. Mamas Health Leukemia Provides overview of the condition, including definitions, causes, symptoms, diagnosis and treatment. http://www.mamashealth.com/leukemia.asp

112. Acute Lymphoblastic Leukemia Acute Lymphoblastic leukemia. Infantile leukemia is associated with high tumor burden, high white counts, organomegaly and CNS involvement. http://gucfm.georgetown.edu/welchjj/netscut/heme_onc/all.html

Acute Lymphoblastic Leukemia Introduction FAB classification Biological classification ALL derived from B cells Cell surface markers and B cell differentiation pre-pre-B ALL pre-B ALL B cell ALL ALL derived from T cells ... Treatment Introduction The acute leukemias account for about one third of childhood cancer, and about three quarters of these leukemias are ALL (the others being AML or acute undifferentiated leukemia). In general, ALL has a better outcome than AML. Lymphoblasts can be distinguished from myeloblasts in a number of ways: Characteristic Lymphoblasts Myeloblasts Chromatin smooth, homogenous more fine Nucleoli indistinct punched out Cytoplasm small rim more abundant Granules rare yes sometimes Auer rods PAS positive glycogen globs small, fine PAS staining MPO Negative Most positive Sudan Black Negative Cytoplasmic lipid stains positive FAB Classification of ALL The FAB Classification relies on morphology, dividing blasts into L1, L2 and L3 by their appearance. These categories are not well related to biology or outcome except for the L3 blasts. These are derived from immunophenotypically distinct mature B cells. Small Larger Large Almost no cytoplasm About 20% cytoplasm Basophilic Cytoplasm Cytoplasmic vacuolization Round to cleaved nucleoli Perinuclear chromatin More prominent nucleoli Biological Classification of ALL ALL blasts are derived from either B-cell or T-cell lineages, as determined by cell surface and other markers. A small percentage of the cells are either so primitive that they do not express enough markers to identify, and these comprise the AUL category. As more markers are elucidated, the number of leukemias falling into this wastebasket category is declining. The mixed cell leukemias represent another difficulty for classification: they are not clearly B or T cells and may represent a very early precursor (perhaps of both lines) or lineage infidelity.

113. Some Moore Cats - Feline Leukemia Story about a cat called Maxwell and his battle with FeLV and his chronic eye problems, including corneal ulcers, entropion, and conjunctivitis. http://www.somemoorecats.com/felv.shtml

June 02, 2004 Pictures, Games, Stories, Cards, Resources, and Moore! Home Photo Gallery Postcards Shoppe Menu About Us Home Callie Chloe Duncan ... Photo Gallery Just Fur Fun Tell a Friend About Us Duncan's Dining Kitty Poll Cat Concentration ... Photo Contest Seriously... Links and Resources Online Shoppe Feline Leukemia Maxwell's Journal ... View our Guestbook Feline Leukemia (FeLV) - One Cat's Experience Related Information: Read Maxwell's Journal - The Diary of a FeLV+ Cat, started January 20, 2000 on his fifth "purrday". Maxwell was included in an article about Feline Leukemia at VetCentric.com.... the article is reprinted here with permission. Maxwell: [ Page 1 Page 2 Article FeLV Diary Maxwell's Story Maxwell came to me as a tiny babycat of about 10 weeks in April 1995. He had been abandoned out in the country near the home of a friend of mine. He found his way to her front porch, and from there, into my home and heart. (You can read more about Maxwell's early story at the Comeback Kitties page where our Dexter's FeLV Resources There are many excellent resources available on the internet addressing this dreadful and heartbreaking disease so I won't try to duplicate that information here. If you have a FeLV+ cat or are interested in more information about the disease, I would encourage you to check out our

114. Feline Leukemia - Do Something! http://www.corax.com/feline/leukemia.html

115. CaringBridge.org - Julianna Julianna Banana is a little girl that was diagnosed with acute lymphoblastic leukemia. Site includes her story, and photos of her. http://www.caringbridge.org/canada/julianna

about CaringBridge home page view guestbook view photos ... make a tribute donation Julianna Banana! Hello everyone, welcome to my web page! My name is Julianna and I live in Winnipeg, Canada, home of Winnie the Pooh. I'm 3 years old, brown hair and brown eyes, single and a non-smoker. My turn-ons include pink clothes, Barbie toys and playing. My turn-offs are medicine and when my brother stands in front of the tv. Please stop by from time to time and see what I'm up to :-) On September 4, 2003, the doctors told mom and dad that I have acute lymphoblastic leukemia, standard risk, pre-B cell type and that I'm on the CCG 1991 treatment plan protocol...whatever that means. Oh well, as long as mom figures out my medicine and dad keeps changing the kitty litter, I'll just keep playing barbies. I have to go back to the hospital one or two times a week. The needles are NO fun at all, those ladies who always SEEM so nice always want to hold me down and stick things in my back. They don't know that I'm taking names and it's payback time when I'm not so little, mwahahaha! My Nonna lives in Brandon, Manitoba, but she just moved in! HOW COOL IS THAT?! Not many kids get their grandmas cooking anytime they want!

116. The Feline Leukemia Pinboard Her 2 sisters both were euthanized within their first year due to complications they developed from the leukemia. Scruffy seemed to do so well. http://www.corax.com/spacelab/pinb_fel.htm

Hey guys. I have a feline leukemia positive cat,her name is Cheetah. I was at work and my mom called me and saud that she hasn't been able to keep anything down for about 24 hours, her nose is dry and warm and not wet like it should be, and she's not playful like she used to be. She's 2 this month. Is this just where she is getting gradually worse? If it is, I don't want to see her suffer. :( Thanks. Retta910@aol.com - Monday, May 31, 2004 at 13:40:47 (EDT) haroldcths@aol.com - Tuesday, May 11, 2004 at 21:13:08 (EDT) haroldcths@aol.com - Tuesday, May 11, 2004 at 21:12:27 (EDT) hello. i have a cat that is felv pos.(or so the traditional vets say). well, i am always worried about her...shes had such a hard life and i came into her life to make it easier. so, i really need some good words and a positive outlook. im worried that she will get sick, and every time she coughs i get nervous and stay up the whole night with her. she doesnt look sick, but shes tired sometimes and she coughs sometimes. please, give feedback. i am taking her to a holistic vet next week. has anyone else taken their cat to one? email me with any words of wisdom....or just to say that it will be ok.

117. Blacksburg Area Volunteers Against Leukemia Organization promoting public awareness of blood related cancers, aiding area patients and programs and increasing the voluntary bone marrow donor registry. http://baval0.tripod.com/fightleukemia/

var cm_role = "live" var cm_host = "tripod.lycos.com" var cm_taxid = "/memberembedded" Check out the NEW Hotbot Tell me when this page is updated Our Purpose Calendar of Events ... Contact Us Blacksburg Area Volunteers Against Leukemia Welcome to our web site! We are Blacksburg residents fighting Leukemia in our area. We do this by promoting public awareness of Leukemia, blood related cancers and the importance of bone marrow donation. We want to help any patients in any way that we can. We are continuously fundraising to offset the high cost of tissue typing for volunteer bone marrow donors. We will run drives to increase the registry of donors. YOU ARE THE PERSON TO VISIT OUR WEBSITE I have signed up to run my first marathon. Click below to follow me from my zero miles a week to running the event..... My TNT experience We are people who have been touched by blood related cancer. Someone we know has been diagnosed or has succumbed to a blood related cancer. If you have ever known anyone with a life threatening illness, The experience is truly a helpless one. The odds of something that I or anyone else does in the name of a specific person are long that it will help that person. But, whoever it is: college student, child, friend or family member. It will happen to someone just like them tomorrow. There is only one way to prevent that. Please take the time to sign our guest book and let us know who you are: We invite you to visit us or attend an event. Our members are more than happy to answer any questions you may have about the organization and how you can join.

118. WellnessBooks.com - 1. Books Childhood leukemia A Guide for Families, Friends and Caregivers (3rd Edition), Childhood leukemia A Guide for Families, Friends and Caregivers (3rd http://members.aol.com/healwell/leukemia/

Leukemia Book Store at WellnessBooks.com We've Moved! Your browser should automatically be redirected to our new location. If not, click here to visit the Leukemia Book Store Webmasters: Please update your links to our new URL at: http://www.wellnessbooks.com/leukemia/

119. EMedicine Health - Leukemia Overview leukemia, Overview, These disturbances are called cancer. leukemia is a cancer of the blood in which blood cells mature abnormally or incompletely. http://www.emedicinehealth.com/articles/25755-1.asp

Search June 2, 2004 Registration Healthcare Professionals High cholesterol can affect children. Is your child at risk? About 1 million people in the United States have Crohn disease. What are treatment options? Is there a connection between IBD and Crohn Disease? About one third of those with diabetes do not know they have it. Are you one? Two million or more Americans have schizophrenia. Is someone you love affected? One third of those with asthma are children. What are the symptoms and triggers? Asthma Cholesterol Crohn Disease Diabetes ... Mental Health You are in: Cancer and Tumors Leukemia Overview Cancer is a process of abnormal cell growth and development. Under normal circumstances, cells are formed, mature, carry out their function, and die. New cells are constantly being formed to take their places. This process can be disturbed in many different ways. Cells can form when they are not needed, fail to mature properly so they can function, or fail to die when they have fulfilled their function. These disturbances are called cancer.

120. Childhood Acute Lymphoblastic Leukemia - Acute Lymphocytic Leukemia In Children Acute Lymphoblastic leukemia Acute lymphoblastic leukemia (ALL) is the most common malignancy of childhood, representing nearly one third of all pediatric http://www.emedicine.com/ped/topic2587.htm

(advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Pediatrics Oncology Acute Lymphoblastic Leukemia Last Updated: September 15, 2003 Rate this Article Email to a Colleague Synonyms and related keywords: acute lymphocytic leukemia, acute lymphatic leukemia, acute lymphoid leukemia, ALL AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Jeffrey E Rubnitz, MD, PhD , Director of Fellowship Training Program, Associate Professor, Departments of Pediatrics and Hematology-Oncology, University of Tennessee and St Jude Children's Research Hospital Jeffrey E Rubnitz, MD, PhD, is a member of the following medical societies: American Society of Hematology Editor(s): Kathleen Sakamoto, MD , Associate Professor, Departments of Pediatrics and Pathology, University of California at Los Angeles and Mattel Children's Hospital; Robert Konop, PharmD

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