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Fachportal Innere Medizin Zeitschriften Medizinische Klinik BDI aktuell ... Englisch A-Z Literatursuche Medline Reisemedizin Rote Liste Leitlinien Patientenservice Kongresskalender , Ernst-Heinrich Scheuermann , Achim Viertel , Helmut Geiger , Inge Scharrer Medizinische Klinik IV, Funktionsbereich Nephrologie, Eingang des Manuskripts: 1. 7. 1997. Z USAMMENFASSUNG Hintergrund: Klinisches Bild: Eine ausgeprägte Thrombophilie, rezidivierende Fehlgeburten sowie eine Thrombozytopenie charakterisieren die klinische Trias des Antiphospholipidsyndroms. Andere klinische Manifestationen umfassen: Migräne, Chorea minor, hämolytische Anämie, Erkrankungen der Herzklappen, Budd-Chiari-Syndrom, rezidivierende Pankreatitiden, intestinale Apoplexie, maligne Hypertonie, Livedo reticularis, Präeklampsie, fetale Wachstumsverzögerungen oder das sogenannte „katastrophale Antiphospholipidantikörpersyndrom". Im Gegensatz zum „primären Antiphospholipidantikörpersyndrom" finden sich Lupusantikoagulanzien und Anticardiolipinantikörper beim „sekundären Antiphospholipidantikörpersyndrom" im Rahmen von Autoimmunerkrankungen, von Neoplasien und Infektionen oder sind mit dem Gebrauch bestimmter Medikamente assoziiert. Therapie: A BSTRACT Antiphospholipid Antibody Syndrome Background: Antiphospholipid antibodies comprise a family of auto-anti- bodies mainly characterized by the presence of the lupus anticoagulant (LA) and anticardiolipin antibodies (ACA).

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