81. Klinefelter's Syndrome: Topic Overview klinefelter s syndrome. Topic Overview. What is klinefelter s syndrome. klinefelter s syndrome is a genetic disorder affecting males. http://www.meritcare.com/hwdb/_followLink.asp?sgml_id=HW183686

82. Klinefelter's Syndrome -- Topic Overview What is klinefelter s syndrome. klinefelter s syndrome is a genetic disorder affecting males. 1. What causes klinefelter s syndrome? http://my.webmd.com/hw/mens_conditions/hw183688.asp

var guid_source = ""; var guid_source_id = ""; //unused var encodedurl = ""; WebMD Today Home WebMD News Center Member Services WebMD University My WebMD Find a Physician Medical Info Check Symptoms Medical Library Quizzes, Calculators Clinical Trials ... Women, Men, Lifestyle Who We Are About WebMD Site Map You are in Choose a Topic All Conditions ADD/ADHD Allergies Alzheimer's Arthritis Asthma Back Pain Breast Cancer Cancer Dental Depression Diabetes Eye Health Heart Disease Hepatitis HIV/AIDS Hypertension Men's Conditions Mental Health Migraines/Headaches Multiple Sclerosis Osteoporosis Parkinson's Sexual Conditions Stroke Weight Control Women's Conditions Health Topics Symptoms Medical Tests Medications ... Credits Klinefelter's Syndrome Topic Overview What is Klinefelter's syndrome Klinefelter's syndrome is a genetic disorder affecting males. In Klinefelter's syndrome, the male has one or more extra X chromosomes . Males normally have one X and one Y chromosome. Males with Klinefelter's syndrome commonly have one extra X chromosome. In rare cases, some males with Klinefelter's syndrome have as many as three or four X chromosomes or one or more extra Y chromosomes. Many men with an extra X chromosome are not aware that they have it and go on to lead normal lives. Males with Klinefelter's syndrome may be described as XXY males or males with XXY syndrome. Klinefelter's syndrome occurs in about 1 in 500 to 1 in 1,000 males.

83. Klinefelter's Syndrome - OhioHealth klinefelter s syndrome occurs only in males. klinefelter s syndrome, Question I am a 34year-old man with klinefelter s syndrome. http://www.ohiohealth.com/healthreference/reference/A8285889-002C-46BD-A52776B42

Home All Health Reference Condition Guides Healthy Living ... General Klinefelter's syndrome Question: I am a 34-year-old man with Klinefelter's syndrome. I'm upset that I can't have children. Is Klinefelter's syndrome hereditary? Can it be cured? No name / No state given Answer: Normally, a male has only one X and one Y chromosome and a female has two of the X chromosomes. In Klinefelter's syndrome, the male has two or more X chromosomes in addition to one Y chromosome. Klinefelter's syndrome usually isn't present in other family members. The extra genetic materials cause abnormal development of the testicles, resulting in decreased production of sperm and male sex hormones. Signs and symptoms of Klinefelter's syndrome can vary but may include: Small testicles Infertility Long arms and legs Enlarged breast tissue (gynecomastia) Scant facial and body hair Decreased sex drive (libido) and function No treatment can correct this genetic abnormality. But testosterone replacement therapy can improve symptoms due to testosterone deficiency. Most men with Klinefelter's syndrome are infertile because they don't make enough sperm. But no man with Klinefelter's syndrome should assume he's infertile without further testing.

84. Klinefelter's Syndrome klinefelter s syndrome is a genetic disorder affecting males. In klinefelter s syndrome, the male has one or more extra X chromosomes . klinefelter s syndrome. http://www.bchealthguide.org/kbase/topic/mini/hw183686/descrip.htm

document.write(''); var hwPrint=1; var hwDocHWID="hw183686"; var hwDocTitle="Klinefelter's Syndrome"; var hwRank="1"; var hwSectionHWID="hw183688"; var hwSectionTitle="Topic Overview"; var hwSource="cn6.0"; var hwProdCfgSerNo="wsh_html_031_s"; var hwDocType="MINI-TOPIC"; Klinefelter's Syndrome XXY males, XXY syndrome Topic Overview What is Klinefelter's syndrome Klinefelter's syndrome is a genetic disorder affecting males. In Klinefelter's syndrome, the male has one or more extra X chromosomes . Males normally have one X and one Y chromosome. Males with Klinefelter's syndrome commonly have one extra X chromosome. In rare cases, some males with Klinefelter's syndrome have as many as three or four X chromosomes or one or more extra Y chromosomes. Many men with an extra X chromosome are not aware that they have it and go on to lead normal lives. Males with Klinefelter's syndrome may be described as XXY males or males with XXY syndrome. Klinefelter's syndrome occurs in about 1 in 500 to 1 in 1,000 males. What causes Klinefelter's syndrome?

85. Klinefelter's Syndrome --- HealthandAge klinefelter s syndrome. klinefelter s syndrome. February 17, 2003 (Reviewed February 23, 2004). Question. I was born with klinefelter s syndrome (XXY). http://www.healthandage.com/Home/gid7=453

June 3, 2004 Home Health Centers HealthandAge Network Caregivers' Center ... Primer on Aging Choose Font Size Normal Large Extra Large Klinefelter's Syndrome Klinefelter's Syndrome February 17, 2003 (Reviewed: February 23, 2004) Question I have a question about my sexuality. I was born with Klinefelter's syndrome (XXY). I get a shot of testosterone every 3 weeks but it does not seem to do much for my libido or anything else. I'm 65, have diabetes mellitus, and am on blood thinners (to prevent clotting in my legs) and I have poor circulation. I guess I should 'hang up my sexual hat', but I didn't find out about the XXY until I was 53, and I went through puberty at 54! Answer Even though you found out that you have Klinefelter's syndrome 11 years ago I'm wondering just how much your physician has explained to you. Here are a few remarks on it. There are 23 pairs of chromosomes found in each cell of the body, and each contain genes that determine our coloring, our features, and our sex. Women inherit two X chromosomes - one from each parent, written XX. Men inherit an X chromosome from their mothers and a Y chromosome from their fathers, written XY. The X chromosome determines whether a child is going to be a male or a female. X-chromosome mutations cause various human genetic disorders, such as Turner's syndrome and Klinefelter's syndrome.

86. Klinefelter's Syndrome --- HealthandAge Normal. Large. Extra Large. klinefelter s syndrome. Home klinefelter S syndrome . klinefelter s syndrome. I was born with klinefelter s syndrome (XXY). http://www.healthandage.com/Home/gm=20!gid7=453

June 3, 2004 Home Health Centers HealthandAge Network Caregivers' Center ... Primer on Aging HealthandAge Poll Are you seeking health information for yourself a family member a friend just browsing Choose Font Size Normal Large Extra Large Klinefelter's Syndrome Home RELATED QUESTION Klinefelter's Syndrome February 17, 2003 (Reviewed: February 23, 2004) Question I have a question about my sexuality. I was born with Klinefelter's syndrome (XXY). I get a shot of testosterone every 3 weeks but it does not seem to do much for my libido or anything else. I'm 65, have diabetes mellitus, and am on blood thinners (to prevent clotting in my legs) and I have poor circulation. I guess I should 'hang up my sexual hat', but I didn't find out about the XXY until I was 53, and I went through puberty at 54! Answer Even though you found out that you have Klinefelter's syndrome 11 years ago I'm wondering just how much your physician has explained to you. Here are a few remarks on it. There are 23 pairs of chromosomes found in each cell of the body, and each contain genes that determine our coloring, our features, and our sex. Women inherit two X chromosomes - one from each parent, written XX. Men inherit an X chromosome from their mothers and a Y chromosome from their fathers, written XY. The X chromosome determines whether a child is going to be a male or a female. X-chromosome mutations cause various human genetic disorders, such as Turner's syndrome and Klinefelter's syndrome.

87. Go Ask Alice!: Klinefelter's Syndrome Miscellaneous. klinefelter s syndrome. Originally Published October 26, 2001 / Updated on May 21, 2004. Printer Friendly Version. Dear Alice,. http://www.goaskalice.columbia.edu/1991.html

Mac users: please note that our site is optimized for the Safari browser Miscellaneous Klinefelter's syndrome Originally Published: October 26, 2001 Dear Alice, Dear Reader, Men who are born with two X chromosomes [or a genotype (genetic information) of XXY instead of the more typical XY] usually develop a condition called Klinefelter's syndrome. Klinefelter's is the most common sex chromosome disorder, affecting approximately 1 in 500 males across all ethnic and racial groups. Because the "extra" chromosome is a sex chromosome, most of the physical effects of Klinefelter's syndrome become apparent during puberty, if at all. Men with Klinefelter's tend to be tall and have decreased facial hair and muscle mass. They are also more likely to have breast development and very small testicles. Some of these physical differences are thought to be the result of decreased testosterone levels. Injections of synthetic testosterone have been found to increase muscle development and bone density, giving men with Klinefelter's syndrome a more traditionally masculine appearance. However, this replenishment of testosterone cannot correct the infertility that most with Klinefelter's have as a result of the condition. Some research suggests that early (recommended by ages 11 - 13 years) testosterone replacement therapy may decrease the incidence and severity of learning disabilities that can be related to having Klinefelter's, potentially improving overall quality of life. Research on the cognitive problems associated with Klinefelter's are still in the early stages though.

88. Health Info Topic klinefelter s syndrome, Back to previous page. Topic Overview What is klinefelter s syndrome. klinefelter s syndrome http://www.pamf.org/health/healthinfo/index.cfm?page=article&sgml_id=hw183686

89. Klinefelter's Syndrome - Wikipedia, The Free Encyclopedia klinefelter s syndrome. From Wikipedia, the free encyclopedia. klinefelter s syndrome is above. What is klinefelter s syndrome? In 1942 http://en.wikipedia.org/wiki/Klinefelter's_syndrome

Klinefelter's syndrome From Wikipedia, the free encyclopedia. Klinefelter's syndrome is a condition caused by a chromosomal abnormality in males (specifically a nondisjunction ); sufferers have a pair of X chromosomes instead of just one. The XXY chromosome arrangement is a common genetic abnormality, occurring as frequently as 1 in 1,000 male births, but the symptoms that may result from having the extra chromosome is less common. Because of this extra chromosome, individuals with the abnormality are usually referred to as "XXY Males" rather than as "suffering from Klinefelter's syndrome." In mammals with more than one X chromosome, the genes on all but one X chromosome are barred from being expressed. This happens in XXY males as well as XX females. A few genes, however, have corresponding genes on the Y chromosome and are not barred. These triploid genes in XXY males may be responsible for the symptoms of Klinefelter's syndrome. In adults, the syndrome is characterised by gynecomastia (enlarged breasts), a rounded body type with abnormal body proportions, sparse facial and body hair , small testes , and an inability to produce sperm . Most XXY males have some degree of language impairment as well. The syndrome is associated with an increased risk of breast cancer, pulmonary disease

90. Bbc.co.uk Health - Ask The Doctor - Klinefelter's Syndrome Ask the Doctor. Q klinefelter s syndrome. My sister s new baby has something called klinefelter s syndrome. What is this, and what will it mean for him? Harry. http://www.bbc.co.uk/health/ask_doctor/klinefelter.shtml

@import url('/includes/tbenh.css') ; Home TV Radio Talk ... A-Z Index WEDNESDAY 2nd June 2004 Text only BBC Homepage Health Home Lifestyle Home ... Help Like this page? Send it to a friend! Ask the Doctor Q: Klinefelter's syndrome My sister's new baby has something called Klinefelter's syndrome. What is this, and what will it mean for him? Harry Dr Trisha Macnair responds Klinefelter's syndrome is a genetic abnormality affecting the chromosomes, where a boy baby has one or more extra X chromosome. Boys normally have an X and a Y chromosome, or XY, while girls have two X chromosomes - they are XX. But in Klinefelter's syndrome the child has XXY, or more rarely XXXY or XXXXY. It's quite common - about 1 in 500 boy babies have Klinefelter's and it is more likely to occur the older the mother. Typical physical features People who have Klinefelter's syndrome tend to have a distinctive physical appearance although in childhood it may go unnoticed and it is often not until puberty that these features develop. They include: a tall thin figure, with long arms

91. Klinefelter, Syndrome : Sites Et Documents Francophones syndrome http://www.chu-rouen.fr/ssf/pathol/klinefeltersyndrome.html

Klinefelter, syndrome Menu général CISMeF Arborescence(s) Klinefelter, syndrome Klinefelter's syndrome endocrinopathies maladies et malformations congénitales, héréditaires et néonatales maladies urologiques et appareil génital mâle Position du mot-clé dans l' (les) arborescence(s) : Vous pouvez consulter toutes les ressources ou seulement les principales ou utiliser l' outil de recherche les recommandations les documents concernant l' enseignement les documents destinés aux patients Ou consulter ci-dessous une sélection des principales ressources : Qualificatifs : diagnostic guide ressources Klinefelter, syndrome de - synonyme : 47 XXY syndrome [Par Dr Morichon-Delvallez N. Site éditeur Orphanet base de données sur les maladies rares et les médicaments orphelins. Direction Générale de la Santé / INSERM ; ; pays : France ; langue : français ; format : html ; accès : gratuit ; non parrainé ; daté de : 2003 ; visité le : 26/05/2003]. mots clés : conseil génétique incidence Klinefelter, syndrome Klinefelter, syndrome ... signes et symptômes type(s) : * association patients guide ressources texte diagnostic Aberrations chromosomiques (Les) [Par M. Le-Marec B (CHU de Rennes, Institut Mère-Enfant, annexe pédiatrique, Hôpital sud).

92. Klinefelter, Syndrome : Arborescences MeSH Translate this page klinefelter, syndrome arborescences MeSH. Menu général CISMeF. Vous pouvez aussi consulter toutes les arborescences des mots http://www.chu-rouen.fr/navimesh/K/naviklinefeltersyndrome.html

Klinefelter, syndrome : arborescences MeSH Menu général CISMeF Vous pouvez aussi consulter toutes les arborescences des mots clés utilisés dans CISMeF maladies urologiques et appareil génital mâle appareil urogénital, maladies malformations urogénitales anomalie différenciation sexuelle ... Klinefelter, syndrome 07 janvier 2004 courriel Menu général CISMeF Haut de page © CHU de Rouen . Toute utilisation partielle ou totale de ce document doit mentionner la source.

93. HealthCentral - General Encyclopedia - Klinefelter's Syndrome klinefelter s syndrome. Causes, incidence, and risk factors klinefelter s syndrome is caused by an extra X chromosome and affects only males. http://www.healthcentral.com/mhc/top/000382.cfm

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94. SupportPath.com: Klinefelter's Syndrome klinefelter s syndrome. klinefelter s syndrome is a chromosomal abnormality found in males. None Listed. Clinical Trials Research on klinefelter s syndrome http://www.supportpath.com/sl_k/klinefelters_syndrome.htm

Klinefelter's Syndrome Klinefelter's Syndrome is a chromosomal abnormality found in males. Most males have one X and one Y chromosome (XY). Males with Klinefelter's Syndrom usually two X chromosomes (XXY) and sometimes more than 2. This chromosomal abnormality affects the normal development of sexual and physical characteristics of boys (see links for further information). Also called: Klinefelter Syndrome Other topics of interest on SupportPath.com: Autoimmune Disorders Diabetes Infertility Self Esteem ... here Online Chats... None Listed View our Online Events Calendar for a list of chats by topic. Online Communities / Message Boards... None Listed Usenet Groups... Note: Your browser must be properly configured to access Usenet groups from this site. None Listed Mailing Lists... None Listed National / International Organizations... UNITED KINGDOM Klinefelter Organisation Website: http://www.klinefelter.org.uk/ Description: UK organization. Date Added: 01/09/2002 Klinefelter's Syndrome Association Website: http://www.akac70.care4free.net/ Description: This organization serves the UK and Ireland.

95. Andrology Australia | Androgen Deficiency | Klinefelter's Syndrome Facts about klinefelter s syndrome. What is klinefelter s syndrome? klinefelter What are the effects of klinefelter s syndrome? klinefelter http://www.andrologyaustralia.org/testosterone/klinefelters.htm

Facts Causes Prevention Diagnosis ... Treatment Klinefelter's Syndrome Causes Diagnosis Treatment Support ... Author Facts about Klinefelter's Syndrome What is Klinefelter's Syndrome? What are the effects of Klinefelter's Syndrome? Testosterone is the most important androgen in men. Androgens are hormones responsible for the development of male characteristics such as hair and beard growth, penile growth, muscle gain, bone strength and fat distribution. Testosterone plays an essential role in reproductive and sexual function in men. References [1] Bojesen A, Juul S, Gravholt CH Prenatal and postnatal prevalence of Klinefelter Syndrome: A national registry study. J Clin Endocrinol Metab 88(2): 622-626 (2003). Quality Information on Male Reproductive Health Top of Page Prostate Disease Testicular Cancer Male Infertility ... Email Webmaster

96. Human Genetics Problem Set Problem 11 Diagnosis of klinefelter s syndrome. klinefelter s syndrome (XXY) is an example of chromosomal aneuploidy that can be readily diagnosed by http://www.biology.arizona.edu/human_bio/problem_sets/human_genetics/11Q.html

Human Genetics Problem Set Problem 11: Diagnosis of Klinefelter's syndrome Klinefelter's syndrome (XXY) is an example of chromosomal aneuploidy that can be readily diagnosed by: A. Behavioral analysis B. Somatic cell genetics C. Karyotyping D. Biochemical analysis E. Pedigree analysis The Biology Project University of Arizona Revised: November 5, 1998 Contact the Development Team http://www.biology.arizona.edu

97. Klinefelter's Syndrome Definition Of Klinefelter's Syndrome. What Is Klinefelter Definition of klinefelter s syndrome in the Dictionary and Thesaurus. klinefelter s syndrome. Word Word. http://www.thefreedictionary.com/Klinefelter's syndrome

Dictionaries: General Computing Medical Legal Encyclopedia Klinefelter's Syndrome Word: Word Starts with Ends with Definition Noun Klinefelter's syndrome - syndrome in males that is characterized by small testes and long legs and enlarged breasts and reduced sperm production and mental retardation; a genetic defect in which an extra X chromosome (XXY) is present in the male Klinefelter syndrome XXY-syndrome syndrome - a pattern of symptoms indicative of some disease Legend: Synonyms Related Words Antonyms Some words with "Klinefelter's Syndrome" in the definition: cervical disc syndrome genetic science genetics Gilles de la Tourette syndrome ... XXY-syndrome Previous General Dictionary Browser Next Klemens Metternich kleptomania kleptomaniac ... Klorvess Full Dictionary Browser klick Klicket Klickitat County (enc.) Klickitat County, Washington (enc.) Klickitat, Washington (enc.) klieg light Klient (enc.) KLIK Rockets Dispensers (enc.) Kliment Voroshilov (enc.) Kliment Yefremovich Voroshilov (enc.) Klimmen-Ransdaal (enc.) Klimt Klin (enc.) Kline Kline (enc.)

98. Klinefelter's Syndrome klinefelter s syndrome,. Print this article, Patients with klinefelter s syndrome are infertile. Azoospermia is seen related to testicular atrophy. http://www.amershamhealth.com/medcyclopaedia/medical/Volume IV 2/KLINEFELTERS SY

Amershamhealth.com Search for: Type a word or a phrase. All forms of the word are searchable. Browse entry words starting with: A B C D ... Other characters Klinefelter's syndrome, (Harry Klinefelter, 20th century, American physician), a syndrome seen in individuals with two or more X chromosomes and one or more Y chromosomes. These individuals are hypogonadic males. The majority of affected individuals are of 47,XXY karyotype (82% of cases). Meiotic nondisjunction accounts for the extra chromosome, which may be of either maternal or paternal origin. Advanced maternal age and irradiation of either parent are risk factors. Klinefelter's syndrome occurs in 1 in 850 live male births, making it a common genetic disease involving the sex chromosomes and the most common cause of male hypogonadism. Hypogonadism is seen in all cases, resulting in elevated gonadotropin levels (especially FSH) and variably reduced testosterone levels. Mean plasma estradiol levels are elevated by an unknown mechanism. The ratio of oestrogens to testosterone determines the extent of femininization. Clinical symptoms are usually not evident until puberty. They include: small atrophic testes with a small penis, eunuchoid body habitus with abnormally long legs, lack of secondary male sexual characterisitics and gynecomastia. The mean IQ is usually lower than that of the general population. Patients with Klinefelter's syndrome are infertile. Azoospermia is seen related to testicular atrophy. In some patients, complete atrophy of the testicular tubules is present and they are replaced by pink, hyaline, collagenous ghosts. In others, apparently normal tubules are interspersed with atrophic tubules. In still others, all tubules are incompletely developed, consisting of cords of cells that have never developed a lumen or progressed to mature spermatogenesis. While some authors contend that Leydig cell hyperplasia is present in patients with Klinefelter's syndrome, others argue that the Leydig cell appears hyperplastic only because of atrophy and crowding of the tubules. In polysomic X individuals (e.g. 48, XXXY or 49, XXXXY), additional genital abnormalities are seen, including cryptorchidism, hypospadias, and more severe testicular hypoplasia.

99. Klinefelter's Syndrome (www.whonamedit.com) klinefelter s syndrome A congenital endocrine disturbance characterized chiefly by dull mentality and/or behavioural problems associated with hypogenitalism http://www.whonamedit.com/synd.cfm/1633.html

Home List categories Eponyms A-Z Biographies by country ... Contact Whonamedit.com does not give medical advice. This survey of medical eponyms and the persons behind them is meant as a general interest site only. No information found here must under any circumstances be used for medical purposes, diagnostically, therapeutically or otherwise. If you, or anybody close to you, is affected, or believe to be affected, by any condition mentioned here: see a doctor. Klinefelter's syndrome Also known as: Klinefelter-Reifenstein-Albright syndrome Klinefelter-Reifenstein syndrome Reifenstein-Albright XXY syndrome Synonyms: Aspermatogenesis-gynaecomastia syndrome, chromosome XXY syndrome, gynaecomastia-aspermatogenesis syndrome, medullary gonadal dysgenesis, primary microorchidism, puberal seminiferous tubule failure, sclerosing tubular degeneration, seminiferous tubule dysgenesis, XXY syndrome. Associated persons: Fuller Albright Harry Fitch Klinefelter, Jun. Edward Conrad Reifenstein jun. Description: A congenital endocrine disturbance characterized chiefly by dull mentality and/or behavioural problems associated with hypogenitalism and hypogonadism. The affected children have small and firm testes, lack of sperm formation, but normal size penis, and gynecomastia (usually minimal). Long limbs and relatively slim and tall statures, but tendency towards obesity in some adults. Other features are immaturity, shyness, lack of judgement, assertive unrealistic activity. The majority of Klinefelter’s individuals have an extra female chromosome, resulting in an XXY pattern and a total of 47 chromosomes instead of 46. Other patterns of chromosomal aberration such as XXY, XXYY, and some mosaic patterns may result in the same syndrome. The most frequent type of intersexuality, one per 500-700 live male births.

100. Cytogenetics Gallery klinefelter s syndrome. 49,XXXXY This karyotype shows a variant of klinefelter s syndrome. Individuals with this syndrome are male http://www.pathology.washington.edu/galleries/Cytogallery/main.php?file=klinefel

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