41. National Anemia Action Council Offers research information about anemia associated with end stage renal disease, chronic kidney disease, cancer, HIV, rheumatoid arthritis, heart disease and diabetes. http://www.anemia.org

42. NEJM -- Polycystic Kidney Disease Review Article from The New England Journal of Medicine Polycystic kidney disease. Next Next. Polycystic kidney disease. Patricia D. Wilson, Ph.D. http://content.nejm.org/cgi/content/short/350/2/151

HOME SEARCH CURRENT ISSUE PAST ISSUES ... HELP Please sign in for full text and personal services Previous Volume 350:151-164 January 8, 2004 Number 2 Next Polycystic Kidney Disease Patricia D. Wilson, Ph.D. Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings. Full Text PDF PDA Full Text Supplementary Material ... Chapters at Harrison's Polycystic kidney diseases are a leading cause of end-stage renal failure and a common indication for dialysis or renal transplantation. Recent advances have led to insights into mechanisms underlying the cause and prognosis of these diseases and suggest new directions for treatment. Polycystic kidney disease may arise sporadically as a developmental abnormality or may be acquired in adult life, but most forms are hereditary. Among the acquired forms, simple cysts can develop in kidneys as a consequence of aging; dialysis, drugs, and hormones can cause multicystic disease ; and renal cysts are often secondary manifestations of genetic Full Text of this Article Autosomal Dominant Polycystic Kidney Disease Autosomal Recessive Polycystic Kidney Disease Familial Nephronophthisis Medullary Cystic Kidney Disease Cell Biology Proliferation and Apoptosis Secretion Polarity Signal Transduction Cilia Molecular Biology PKD Genes and Mutations Polycystic Kidney Disease Proteins Polycystin-1 Polycystin-2 Fibrocystin Nephrocystin Functions of Polycystins Developmental Regulation and Programming Prospects for Prognosis and Therapy

43. Welcome To Janssen-Ortho Inc. Canadian pharmaceutical company that develops drugs in the following therapeutic areas mental wellness, anemia and fatigue, women's health, digestive disorders, kidney disease, infectious diseases and wound healing. http://www.janssen-ortho.com/

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44. Kidney Diseases  (Easy To Read) For many years before that point, kidney disease of diabetes exists as a silent process. How can I help keep my diabetes from becoming kidney disease? http://www.4woman.gov/faq/Easyread/kidney-etr.htm

Search our database by Health Topic or enter your own keywords Kidney Diseases - Easy to Read How do healthy kidneys work? What happens when my kidneys stop working? What is the treatment for end-stage renal disease (ESRD)? What are the signs of kidney failure? ... What is the urinary tract? How do healthy kidneys work? Healthy kidneys clean the blood by taking away extra water and wastes. The kidneys turn the extra water and waste into urine. Kidneys also make hormones that keep your bones strong and your blood healthy. They keep a stable balance of salts and other substances in your blood. What happens when my kidneys stop working? When both your kidneys stop working, your body holds fluids, your blood pressure goes up, and harmful wastes build up in your body. Also, your body does not make enough red blood cells. This is known as end-stage renal disease (ESRD). ESRD is the final stage of the slow worsening of the kidneys. More than 50,000 people have ESRD each year in the United States. What is the treatment for end-stage renal disease (ESRD)? The two main treatments for ESRD are dialysis and kidney transplantation. Dialysis uses a machine or special tubes to clean your blood. Kidney transplantation means that you get a healthy kidney from a donor or relative put into your body to replace your kidneys that are not working.

45. BWH Renal Division Home Page The Laboratory of Inherited kidney disease at the Harvard Medical School and Brigham and Women's Hospital is conducting research to identify genes involved in the development of focal segmental glomerulosclerosis and nephrotic syndrome. http://www.brighamandwomens.org/patient/researchGroupDetails.asp?dept_id=38&

46. Polycystic Kidney Disease What is Polycystic kidney disease? Polycystic kidney disease has many symptoms. Individuals with PKD may not experience all of the symptoms. http://www.mamashealth.com/poly.asp

Mamashealth.com Home Category Links About Us Allergies Blood Diseases Cancers ... Read Health Books Links Email Mama What is Polycystic Kidney Disease? Polycystic kidney disease (PKD) is an inherited disease characterized by the growth of numerous cysts filled with fluid in the kidneys. PKD cysts can slowly replace much of the mass of the kidneys, reducing kidney function and leading to kidney failure. PKD can also cause cysts in the liver and problems in other organs, such as the heart and blood vessels in the brain. The cysts may also cause pain or may get infected. There are two types of PKD ( autosomal dominant and autosomal recessive Types? Autosomal dominant PKD is inherited. This kind of PKD accounts for about 90 percent of all PKD cases. The term "Autosomal dominant" means that if one parent has the disease, there is a 50 percent chance that the disease will pass to a child. Autosomal recessive PKD is also inherited. This type of PKD is rare. Parents that do not have the disease can have a child with the disease. How can this happen? Ib both parents carry the recessive gene and pass the recessive gene to their child, the child will have two recessive genes and develop the disease.(inherited). What are the symptoms of PKD?

47. Kidney Disease And Lupus - Lupus Foundation Of America, Inc. 202349-1156 Contact Us. Words of Caution. kidney disease And Lupus John H. Klippel, MD Medical Director, The Arthritis Foundation. http://www.lupus.org/education/brochures/kidney.html

Home About LFA Mailing List Chapter Locator ... Brochures search: Choose Section - Education - Support - LFA Research - What's New? - LFA In Action - News - Research - Awareness Lupus Disease - Cutaneous (skin) - Drug-Induced - Neonatal - Overlap - Systemic Education Information and Publications Support LFA Research ... What's New? Lupus Foundation of America, Inc. www.lupus.org 2000 L Street, N.W., Suite 710 Washington, DC 20036 Phone 202-349-1155 Fax 202-349-1156 Contact Us Words of Caution Kidney Disease And Lupus John H. Klippel, M.D. Medical Director, The Arthritis Foundation Clinical Course Of Lupus Nephritis Studies To Evaluate Lupus Nephritis Urinalysis Blood work 24-Hour urine collection Imaging studies Kidney biopsy World Health Organization (WHO) Classification System for Lupus Nephritis Treatment And Therapy Corticosteroids

48. EID V3 N2: Polycystic Kidney Disease: An Unrecognized Emerging Infectious Diseas Polycystic kidney disease An Unrecognized Emerging Infectious Disease? Polycystic kidney disease (PKD) is one of the most common genetic diseases in humans. http://www.cdc.gov/ncidod/eid/vol3no2/miller.htm

Synopses Polycystic Kidney Disease: An Unrecognized Emerging Infectious Disease? Polycystic kidney disease (PKD) is one of the most common genetic diseases in humans. We contend that it may be an emerging infectious disease and/or microbial toxicosis in a vulnerable human subpopulation. Use of a differential activation protocol for the Limulus amebocyte lysate (LAL) assay showed bacterial endotoxin and fungal (1 3)-ß-D-glucans in cyst fluids from human kidneys with PKD. Fatty acid analysis of cyst fluid confirmed the presence of 3-hydroxy fatty acids characteristic of endotoxin. Tissue and cyst fluid from three PKD patients were examined for fungal components. Serologic tests showed Fusarium Aspergillus, and Candida antigens. IgE, but not IgG, reactive with Fusarium and Candida were also detected in cyst fluid. Fungal DNA was detected in kidney tissue and cyst fluid from these three PKD patients, but not in healthy human kidney tissue. We examine the intertwined nature of the actions of endotoxin and fungal components, sphingolipid biology in PKD, the structure of PKD gene products, infections, and integrity of gut function to establish a mechanistic hypothesis for microbial provocation of human cystic disease. Proof of this hypothesis will require identification of the microbes and microbial components involved and multifaceted studies of PKD cell biology. Examining the hypothesis that polycystic kidney disease (PKD) is an emerging infectious disease and/or microbial toxicosis in a vulnerable population of humans must begin with a review of the conceptual tools that relate disease etiology and progression to the identification of microbes, their cellular components, and shed toxins in affected persons (

49. Kidney Diseases HomePage Welcome to the Canadian Pediatric kidney disease Research Centre Website. Centre canadien de recherche sur les maladies rénales infantiles. http://www.cheori.org/cpkdrc/kidney.htm

Welcome to the Canadian Pediatric Kidney Disease Research Centre Website Centre canadien de recherche sur les maladies rénales infantiles Nephrology Service - Service de nephrologie Children's Hospital of Eastern Ontario Hôpital pour enfants de l'est de l'Ontario Director: Peter N. McLaine, M.D., F.R.C.P.C. Associate Director: Ms. Elaine Orrbine Please follow links below: About CPKDRC Hamburger Disease Information CPKDRC Research Related Worldwide Websites Last modified: July 27, 2000 Send mail to Creery@cheo.on.ca with questions or comments about this web site.

50. The Cleveland Clinic Urological Institute The Institute offers a full range of care for Urology problems including kidney disease, prostate disorders, kidney transplant, incontinence, impototence, infertility. (Ohio) http://www.clevelandclinic.org/urology/general/about.htm

Welcome to The Cleveland Clinic The Cleveland Clinic Glickman Urological Institute is recognized worldwide for excellence in patient care, teaching and research. Every year since 1990, has ranked the Glickman Urological Institute the best in Ohio and one of the top five urology departments in the United States. In each of those years, Chairman, Glickman Urological Institute (Dr. Novick) In addition to The Cleveland Clinic main campus, you will find our urologists in the community at The Cleveland Clinic Family Health Centers and in our affiliated medical offices. Whether your doctor refers you here or you make an appointment on your own, you can feel comfortable in knowing that the doctor who will care for you is experienced in diagnosing and treating many patients with your same problem. We offer the full range of care for urology problems in adults and children, including kidney disease; bladder control; prostate disorders; sexual dysfunction/impotence; male infertility; testicular, bladder, prostate, adrenal and kidney cancer; chronic urinary tract infections and obstructions; pediatric urology; kidney and pancreas transplantation; kidney stones; and laparoscopic surgery.

51. RENALNET HOME PAGE Provides a clearinghouse for information on the cause, treatment and management of kidney disease and ESRD. Conference rooms for various specialties, job mart and dialysis unit search. http://www.renalnet.org/

Site Search Add/Edit Your Link ... Book Gamewood’s EMR Enables Compliance with New Medicare MCP Rules New Site Highlight Nursing Schools Jobs and Resumes Nursing Employment Applications is constantly trying to improve our resource base. We want your input into what resources will add value to your work and participation in the renal healthcare field. We would also like to thank you for using the RENALNET Information Service and for our Sponsors' dedication to this new medium. Suggestions and Comments are welcome. Gamewood, Inc. For questions or comments about this page, please contact Webmaster D I S C L A I M E R The linked sites are continually updated by submissions from both RENALNET and visitors. RENALNET can take neither credit nor responsibility for the information contained in each. Our hope is that these links are useful and invite you to add others you feel would be of interest to the nephrology community.

52. Kidney Disease Physical Examination. Physical examination may reveal the presence of abnormalities that guide your veterinarinan to consider whether there is kidney disease. http://www.newmanveterinary.com/kidney.html

KIDNEYFAILURE To Pee or Not to Pee....AAAaaahhhhhh Sections covered: Kidney Basics, Kidney Failure Acute Renal Failure ChronicRenal Failure Diagnostic Approach ... Treatment Plan KidneyBasics: The kidney is really a multifunctional organ, controlling not only the conservation of fluid and the removal of bodily wastes , but also the regulation of bone and calcium (including vitamin D) metabolism bone marrow (red blood cell ) activity and electrolyte concentrations Conservation Think about the kidney as a container holding thousands of individual filtering units (each called a "nephron") with tiny pores. Blood passes through the kidney, and in the process is routed through each of these filters; toxins and other wastes are removed, most of the fluid (about 95%) is reabsorbed back to the bloodstream (water is conserved), electrolyte concentrations (primarily sodium, potassium, calcium, phosphorus, chloride) are delicately adjusted, and urine is produced. This urine is stored in the urinary bladder until it is voided. The kidney is responsible for providing precursor for the synthesis of Vitamin D ; Vitamin D is necessary for the absorption of calcium from the gastrointestinal tract. In addition, the regulation of concentrations of calcium and phosphorus is also determined by the action of

53. Polycystic Kidney Disease Describes symptoms, treatment and diagnosis. http://www.niddk.nih.gov/health/kidney/pubs/polycyst/polycyst.htm

Email To A Friend Home : Polycystic Kidney Disease Polycystic Kidney Disease On this page: Autosomal Dominant PKD Autosomal Recessive PKD Acquired Cystic Kidney Disease The Search for PKD Genes ... For More Information Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys. The cysts are filled with fluid. PKD cysts can slowly replace much of the mass of the kidneys, reducing kidney function and leading to kidney failure. The kidneys are two organs, each about the size of a fist, located in the upper part of a person's abdomen, toward the back. The kidneys filter wastes from the blood to form urine. They also regulate amounts of certain vital substances in the body. When PKD causes kidneys to failwhich usually happens only after many yearsthe patient requires dialysis or kidney transplantation. About one-half of people with the major type of PKD progress to kidney failure, i.e., end-stage renal disease (ESRD). PKD can cause cysts in the liver and problems in other organs, such as the heart and blood vessels in the brain. These complications help doctors distinguish PKD from the usually harmless "simple" cysts that often form in the kidneys in later years of life. In the United States, about 500,000 people have PKD, and it is the fourth leading cause of kidney failure. Medical professionals describe two major inherited forms of PKD and a noninherited form:

54. Colorado HealthSite ~ Kidney Disease And Dialysis Center kidney disease and Dialysis Center. This center is enhanced with an CHS dictionary. kidney disease Definitions, Facts, Statistics. http://www.coloradohealthsite.org/dialysis/dialmain.html

Kidney Disease and Dialysis Center This center is enhanced with an CHS dictionary Related Sites Diabetes Heart Disease Hypertension Lupus ... Exercise Related Links Minority Health Library General Health Links General Information Library Drug and Patient Alerts View all Alerts The CHS Pledge Patients and Health Care Providers: Read this important pledge, it may change your life! Kidney Disease: Definitions, Facts, Statistics. The information in this center is from the National Institute of Diabetes, Digestive, and Kidney Disease of the NIH. Kidney Dialysis: Definitions, Facts, Questions and Answers, and Statistics. The information in this center is from the National Institutes of Health and the National Kidney Foundation. Primer on Dialysis Blood Chemistries Dialysis patients and their families can read here important information that may prolong lives! Kidney Dialysis Centers in the US. This site provides information on End Stage Renal Disease (ESRD) Dialysis Centers in the US. Treatment Centers for Kidney Disease Here you'll find information on Hospitals for the treatment of Kidney Diseases. Kidney Disease and Kidney Dialysis Developments.

55. Adult Polycystic Kidney Disease - General Practice Notebook Information with emphasis on clinical aspects. http://www.gpnotebook.co.uk/MedwebPage.cfm?ID=-1945763840

56. Discovery Health Polycystic Kidney Disease Polycystic kidney disease (PKD) is an inherited condition that results in abnormally formed kidneys. It also causes throughout the body. http://health.discovery.com/diseasesandcond/encyclopedia/1708.html

57. The American Kidney Fund - Helping Kidney Patients In Need Information about this national voluntary health organization, as well as kidney disease facts. http://www.kidneyfund.org

Welcome! The American Kidney Fund is our nation's leading voluntary health organization serving people with and at risk for kidney disease through direct financial assistance, comprehensive education, clinical research and community service programs. Forbes magazine named the American Kidney Fund as one of only 10 Gold Star charities from its annual list of 200 nonprofit organizations ("Genuinely Needy," December 8, 2003) The American Kidney Fund was named by Reader's Digest as one of 12 "Best Charities" in the United States ("The Best Charities: Who's Worth Trusting with Your Donated Dollars" November 2003). ("The Best Charities," November 2003) American Kidney Fund also received a 4-Star Charity Rating (Exceptional) for the third year in a row from Charity Navigator, an on-line web site that helps individuals make informed giving decisions by providing information on more than 2,500 charities and by evaluating the financial health of each of these charities. Click here or on the "4-Star" symbol at the right for more details!

58. Discovery Health Diet For Kidney Disease There are two types of diets for kidney disease. search, diet for kidney disease. By Susan Harrow Rago, RD, MS. Images (click to view larger image). http://health.discovery.com/diseasesandcond/encyclopedia/1895.html

59. The Internet Vet Column, Volume 2, Number 7 This Internet Vet Column comes to you from Dr. Derek Duval. Feline kidney disease. Uremic toxins are responsible for many of the signs of kidney disease. http://mailer.fsu.edu/~jmcnair/netvet.html

The Internet Vet Column Tue, Feb 28 1995 This Internet Vet Column comes to you from Dr. Derek Duval. Feline Kidney Disease I received a number of letters requesting information about kidney disease in cats and how diet may be important in its cause and treatment. Many cats will develop renal (kidney) insufficiency as they age. With age the kidneys will loose nephrons (the functional unit of the kidney) and renal failure will result. The kidney (like the liver) has a large built in reserve capacity. By the time we see signs are renal insufficiency 60-75% of the renal mass is lost. The first signs are usually loss of the ability to concentrate the urine which results in increased drinking and urinating. With more damage the toxins that are normally filtered by the kidney begin to build up and can cause depression, decreased appetite, a foul odor to the breath, oral ulceration, and vomiting. In the end stage of renal failure, a low body temperature, seizures, and severe depression and coma can result. In the urine we look for signs of infection, ability to concentrate, and loss of protein. When cats with healthy kidneys become dehydrated the urine will become concentrated. Cats with renal insufficiency cannot concentrate their urine despite being dehydrated. Therefore, a urine sample is very important to the evaluation of renal disease.

60. The Feline PKD Home Page; Information About "Autosomal Dominant Polycystic Kidne Information about Autosomal Dominant Polycystic kidney disease, Feline PKD, PKD in cats. Autosomal Dominant Polycystic kidney disease in. http://www.felinepkd.com/

Home Basic Information, flyer Links to more PKD information Ultrasound Testing Form ... News This web site was opened to spread information about Feline PKD Autosomal Dominant Polycystic Kidney Disease in cats The main studies in this disease in cats have so far been done in Persian Cats and crosses between Persians and Domestic Shorthairs. This is the reason why mainly Persian Cats (and Exotic Shorthairs) are mentioned in the various articles/texts. My recommendation is that breeders of other breeds as well respect the presence of this dominantly inherited disease, and consider to have their breeding cats scanned by ultrasound in order to detect possible PKD. Marie Thiers Please, report broken links - thank you! April 4, 1995 - September 18, 2001 Autosomal Dominant Polycystic Kidney Disease in Persians / Exotic Shorthairs PKD / ADPKD What is Polycystic Kidney Disease - PKD? Polycystic Kidney Disease is an inherited kidney disease that has been found in Persian/Exotic cats. Feline Polycystic Kidney Disease (PKD) has been reported sporadically in the literature since 1967, but actual study into this renal disease did not begin until 1990. In1990 an affected female Persian was referred to the Ohio State University teaching hospital with symptoms of renal failure. Offspring of this female were used to start a colony and begin research into this condition.

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