21. Juvenile Rheumatoid Arthritis juvenile rheumatoid arthritis. What is juvenile rheumatoid arthritis? How Is juvenile rheumatoid arthritis Different From Adult Rheumatoid Arthritis? http://www.med.umich.edu/1libr/pa/umarthri14.htm

Pediatric Health Topics All Health Topics Mott Children's Hospital Pediatric Services ... Find a UMHS Doctor Search Pediatric Topics Search All Topics This information is approved and/or reviewed by U-M Health System providers but it is not a tool for self-diagnosis or a substitute for medical treatment. You should speak to your physician or make an appointment to be seen if you have questions or concerns about this information or your medical condition. Juvenile Rheumatoid Arthritis What is Juvenile Rheumatoid Arthritis? Juvenile rheumatoid arthritis (JRA) is arthritis that causes joint inflammation and stiffness for more than 6 weeks in a child of 16 years of age or less. Inflammation causes redness, swelling, warmth, and soreness in the joints, although many children with JRA do not complain of joint pain. Any joint can be affected and inflammation may limit the mobility of affected joints. How Is Juvenile Rheumatoid Arthritis Different From Adult Rheumatoid Arthritis?

22. Pediatric Advisor 2003.2: Juvenile Rheumatoid Arthritis juvenile rheumatoid arthritis. What is juvenile rheumatoid arthritis? juvenile rheumatoid arthritis (JRA) is the most common form of arthritis in children. http://www.med.umich.edu/1libr/pa/pa_jra_hhg.htm

Pediatric Health Topics All Health Topics Mott Children's Hospital Pediatric Services ... Find a UMHS Doctor Search Pediatric Topics Search All Topics This information is approved and/or reviewed by U-M Health System providers but it is not a tool for self-diagnosis or a substitute for medical treatment. You should speak to your physician or make an appointment to be seen if you have questions or concerns about this information or your medical condition. Index Resource List Juvenile Rheumatoid Arthritis What is juvenile rheumatoid arthritis? Juvenile rheumatoid arthritis (JRA) is the most common form of arthritis in children. As many as half the children with this condition have a mild form and have few problems. However, some forms of this disease can produce long-term problems. There are three types of JRA: Pauciarticular JRA affects 4 or fewer joints and may cause inflammation of the eye. The joints most likely to be affected are the knees, elbows, wrists, or ankles. This is the most common type of JRA. Half of the children with JRA have this type. Polyarticular JRA affects many joints (5 or more). About 30% of children with JRA have this type. The smaller joints like those in the hands and feet may be affected as well as large joints.

23. Juvenile Rheumatoid Arthritis juvenile rheumatoid arthritis Guide picks. juvenile rheumatoid arthritis generally refers to people affected by inflammatory arthritis under the age of sixteen. http://arthritis.about.com/cs/jra/

zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') About Arthritis Juvenile Arthritis Home Essentials zau(256,152,145,'gob','http://z.about.com/5/ad/go.htm?gs='+gs,''); Learn the Basics Medications/Supplements Arthritis by Anatomy Assistive Devices ... Help zau(256,138,125,'el','http://z.about.com/0/ip/417/0.htm','');w(xb+xb); Stay Current Subscribe to the About Arthritis newsletter. zau(256,152,100,'hs','http://z.about.com/5/ad/hs.htm?zIhsid=00',''); Search Arthritis Juvenile Rheumatoid Arthritis Juvenile rheumatoid arthritis generally refers to people affected by inflammatory arthritis under the age of sixteen. Typically, the course of rheumatoid arthritis is different in children and adults. Alphabetical Recent Arthritis: A Children's Disease Too Arthritis is not just an old person's disease. The disease affects approximately 285,000 American children. Marrow Transplant For JCA Severe cases of juvenile chronic arthritis may benefit from an experimental treatment known as autologous hemopoietic stem-cell transplantation. More Categories Up a category JRA Basics (5) JRA Research (7) JRA Support (4) ... User Agreement

24. Juvenile Rheumatoid Arthritis Arthritis, juvenile rheumatoid arthritis. juvenile rheumatoid arthritis generally refers to people affected by inflammatory arthritis under the age of sixteen. http://arthritis.about.com/od/jra/

zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') About Arthritis Juvenile Arthritis Home Essentials zau(256,152,145,'gob','http://z.about.com/5/ad/go.htm?gs='+gs,''); Learn the Basics Medications/Supplements Arthritis by Anatomy Assistive Devices ... Help zau(256,138,125,'el','http://z.about.com/0/ip/417/0.htm','');w(xb+xb); Stay Current Subscribe to the About Arthritis newsletter. zau(256,152,100,'hs','http://z.about.com/5/ad/hs.htm?zIhsid=00',''); Search Arthritis Juvenile Rheumatoid Arthritis Juvenile rheumatoid arthritis generally refers to people affected by inflammatory arthritis under the age of sixteen. Typically, the course of rheumatoid arthritis is different in children and adults. Alphabetical Recent Arthritis: A Children's Disease Too Arthritis is not just an old person's disease. The disease affects approximately 285,000 American children. Marrow Transplant For JCA Severe cases of juvenile chronic arthritis may benefit from an experimental treatment known as autologous hemopoietic stem-cell transplantation. More Categories Up a category JRA Basics (5) JRA Research (7) JRA Support (4) ... User Agreement

25. Juvenile Arthritis - Juvenile Rheumatoid Arthritis Last updated June 7, 2003 juvenile rheumatoid arthritis. Figure 1. There are three main types of juvenile rheumatoid arthritis Polyarticular JRA. http://www.orthop.washington.edu/arthritis/types/juvenilearthritis/03

Home About Us Clinics Physicians ... Contact Us A program of Table of contents Introduction About juvenile arthritis Juvenile rheumatoid arthritis Symptoms ... View article with questions External links American Juvenile Arthritis Organization (AJAO) "Classification of Juvenile Chronic Idiopathic Arthropathies," technical information from the Bulletin on the Rheumatic Diseases [Top] Juvenile Arthritis Edited by Frederick A. Matsen III, M.D. Last updated June 7, 2003 Juvenile rheumatoid arthritis Figure 1 - Normal joint versus inflamed joint Symptoms Arthritis is characterized by four major observable changes in the joints. However, since JRA affects each child differently, your child may not experience all of these changes. Children also vary in the degree to which they are affected by any particular symptom. The most common features of JRA are: joint inflammation joint contracture joint damage altered growth Other symptoms your child may experience include joint stiffness following decreased activity and muscle (and other soft-tissue) weakness. Joint inflammation is the most common symptom of JRA. It causes heat, pain, swelling, and stiffness in joints. The lining of the

26. MARRTC: Welcome To The Missouri Arthritis Rehabilitation Research And Training C Conditions http://www.muhealth.org/~arthritis/ja/

Conditions General Arthritis Rheumatoid Arthritis Osteoarthritis Juvenile Arthritis ... Other Conditions Arthritis in Missouri Calendar State Resources Arthritis Centers JA Coordinators MARRTC About Us Spotlight Publications Contact Us ... Newsletter We cannot diagnose medical conditions or give treatment recommendations via the Internet or email. Please see your health-care provider if you have specific concerns about your condition. Section 508 Access Arthritis News and Research Safe Anti-inflammatory for Older People (May 29, 2004 - The Lancet) Arthritis Drug Linked to Heart Failure (May 27, 2004 - WebMD Medical News) Supplemental New Drug Application Submitted (May 31, 2004 - Arthritis Society) Women's Health Group Mobilizes to Combat Arthritis (May 27, 2004 - Arthritis Society) AARP: Drug Prices Soaring (May 26, 2004 - USA Today) Treating Arthritis Ups Employment Prospects (May 26, 2004 - Reuters Health) Intense Workouts Preserve Bone (May 24, 2004 - HealthDayNews) Early Treatment Suggested for Osteoporosis (May 24, 2004 - Associated Press) Pain Linked to Job Stress (May 20, 2004 - NewsRx.com)

27. Juvenile Rheumatoid Arthritis, Cincinnati Children's Hospital Medical Center Cincinnati Childrens Hospital Medical Center Rheumatology Division responds to parents frequently asked questions about juvenile rheumatoid arthritis and other http://www.cincinnatichildrens.org/health/info/rheumatology/diagnose/jra.htm

Home Contact Us Site Map Go to Advanced Search ... Conditions and Diagnoses Juvenile Rheumatoid Arthritis Overview Rheumatic Fever Overview Conditions and Diagnoses Juvenile Rheumatoid Arthritis What is Juvenile Rheumatoid Arthritis? How common is the diagnosis of JRA? How do we make the diagnosis? What is going on inside the joints? ... What are the laboratory tests that you order for my child to help make the diagnosis? What is Juvenile Rheumatoid Arthritis? There are several types of Juvenile Rheumatoid Arthritis (JRA). Some of the children have arthritis ranging from very mild limited joint involvement to severe systemic disease associated with high fever, rash, and lymph node enlargement. We will explain the different types of JRA in more detail. Briefly, the three major subtypes include: systemic, polyarticular and pauciarticular. In other countries, these diseases may be called Juvenile Arthritis or Juvenile Chronic Arthritis which omits the "rheumatoid." The name of the diagnosis could change again in a few years as the pediatric rheumatologists around the world discuss and learn more about the disease. Return to top How common is the diagnosis of JRA?

28. Virtual Children's Hospital: CQQA: Juvenile Rheumatoid Arthritis (JRA) Pediatrics Common Questions, Quick Answers. juvenile rheumatoid arthritis (JRA). Donna What is juvenile rheumatoid arthritis? Juvenile http://www.vh.org/pediatric/patient/pediatrics/cqqa/jra.html

Pediatrics Common Questions, Quick Answers Juvenile Rheumatoid Arthritis (JRA) Donna D'Alessandro, M.D. Lindsay Huth, B.A. Peer Review Status: Internally Reviewed Creation Date: May 2002 Last Revision Date: May 2002 Common Questions, Quick Answers What is juvenile rheumatoid arthritis? What causes it? Who can get it? ... When should I call the doctor? What is juvenile rheumatoid arthritis? Juvenile rheumatoid arthritis is also known as JRA. It is arthritis that affects children age 16 or younger. In JRA, the body's immune system starts to attack instead of protect the body's tissues. The attack can cause redness, swelling, and pain in the joints. There are three main types of JRA. They include pauciarticular, polyarticular, and systemic. Ask your doctor. What causes it? The cause is not known. It may be due to both genetic factors (from parents) and environmental factors (for example, from infections). Who can get it? Children age 16 and under can get JRA. It is more common in females. What are the signs and symptoms? Symptoms of JRA usually show up around the age of 4 or 5. To be diagnosed for JRA, symptoms must last at least 6 weeks. They may include:

29. Virtual Children's Hospital: Paediapaedia: Juvenile Rheumatoid Arthritis (JRA) Paediapaedia Musculoskeletal Diseases juvenile rheumatoid arthritis (JRA). Michael P. D Alessandro, MD Peer Review Status Internally Peer Reviewed http://www.vh.org/pediatric/provider/radiology/PAP/MSDiseases/JRA.html

Paediapaedia: Musculoskeletal Diseases Juvenile Rheumatoid Arthritis (JRA) Michael P. D'Alessandro, M.D. Peer Review Status: Internally Peer Reviewed Clinical Presentation: There are two distinct types in children: (1) Seropositive (adult) type which accounts for 15% of the cases in children, has a female predominance, the age of onset is less than 10 years old, it involves the hands predominantly, then the wrist, feet, knees, hips. (2) Stills disease is seronegative, affects the knees, wrists, carpus, ankles, tarsus, cervical spine and has 3 variants (systemic, polyarticular, monarticular or pauciarticular). Etiology/Pathophysiology: Is a connective tissue disease with a predilection for joint involvement. Pathologically is the same as adult rheumatoid arthritis but they differ in clinical presentation, joint involvement and radiographic findings. Distribution is: knee (90% ), ankle (70% ), wrist (70% ), elbow (40% ), hip (35% ), and shoulder. Pathology: Not applicable Imaging Findings: In legs symmetric bilateral periarticular osteopenia involving the epiphyses and metaphyses is seen with overgrowth of the distal femoral and proximal tibial epiphyses, expansion of the intercondylar notch, and epiphyseal erosion with decreased joint space. In the hands periarticular osteopenia is seen around the metatarsal phalangeal and interphalangeal joints with swelling around the wrists and joints of fingers, accelerated skeletal maturation, erosive changes in the carpal bones, distal radius, and ulna with joint space narrowing. The spine is also involved in up to 70% of patients and you see soft tissue swelling, destruction and obliteration of articular surfaces and joint spaces, generalized rarefaction of bone, and focal subchondral necrosis. Affects the true joints between the articular facets the most, and does not affect synarthroses like the intervertebral discs. Diffuse ankylosis of posterior articular joints without disc space abnormalities is diagnostic of JRA.

30. HealthCentral - General Encyclopedia - Juvenile Rheumatoid Arthritis General Health Encyclopedia, juvenile rheumatoid arthritis. damage. The cause of juvenile rheumatoid arthritis is unknown. Growth http://www.healthcentral.com/mhc/top/000451.cfm

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31. Juvenile Rheumatoid Arthritis, From Arthritis.com juvenile rheumatoid arthritis is defined as causing joint inflammation and stiffness for more than six weeks in children under 16 years of age. http://www.arthritis.com/1_2_3.asp

Personalize This Site Log In Glossary Site Map Search Go Have you been diagnosed with arthritis? Yes No About Arthritis What is Osteoarthritis? What is Rheumatoid Arthritis? Other ... Home About Arthritis What is Rheumatoid Arthritis? Related Links: Information you can use Symptoms, ... Arthritis Juvenile rheumatoid arthritis (JRA) is defined as causing joint inflammation and stiffness for more than six weeks in children under 16 years of age. It is estimated that between 30,000 and 50,000 children in the United States have JRA, making it the most common rheumatic disorder among this age group. Although the causes of JRA are not well understood and no cure exists, medications are available to reduce swelling and pain. In contrast to adults with rheumatoid arthritis, who typically have lifelong symptoms, more than half of those children with JRA will outgrow the disease. Complicating the diagnosis of JRA is the fact that many adult forms of arthritis and rheumatic diseases Three different types of JRA have been classified according to their symptoms and the number of joints involved: Pauciarticular.

32. Rheumatoid Arthritis Information, From Arthritis.com of 20 and 50. 3 , 5 , 7 However, young children can develop a form of RA called juvenile rheumatoid arthritis. If you think you http://www.arthritis.com/1_2.asp

Personalize This Site Log In Glossary Site Map Search Go Have you been diagnosed with arthritis? Yes No About Arthritis What is Osteoarthritis? What is Rheumatoid Arthritis? Other ... Home About Arthritis What is Rheumatoid Arthritis? Related Links: Information you can use Symptoms, ... Arthritis Rheumatoid arthritis (RA) involves inflammation of the lining of many different joints in your body. In some people, RA can also affect other parts of the body, including the blood, the lungs, and the heart. Inflammation of the joint lining, called the synovium , can cause pain, stiffness, swelling, warmth, and redness. The affected joint may also lose its shape, resulting in loss of normal movement. RA can last a long time, and can be a disease of flares (active) and remissions (little to no activity). View our animation to see how inflammation and joint damage progress in rheumatoid arthritis. RA affects about 2.1 million Americans, or about 1% of the adult population in the United States. This disease is two to three times more common in women than in men, and generally affects people between the ages of 20 and 50. However, young children can develop a form of RA called

33. Orthoseek | Orthopedic Topics | Juvenile Rheumatoid Arthritis (JRA) What is JRA? JRA is rheumatoid arthritis in children. Like in adults, the disease is due to an autoimmune disorder. Unlike in adults http://www.orthoseek.com/articles/jrarthritis.html

Juvenile Rheumatoid Arthritis (JRA) What is JRA? JRA is rheumatoid arthritis in children. Like in adults, the disease is due to an auto-immune disorder. Unlike in adults, the clinical pattern can differ markedly. What are the symptoms? JRA can present in several different ways. Pauciarticular arthritis. In these children, four or fewer joints are involved. The commonest joints involved are the knee and ankle. In 50% of cases, only one joint, commonly the knee is involved. The pain and swelling of the joint comes on gradually in a child typically 2 to 4 years of age. Girls are more frequently involved than boys. The child has no fever, is not sick, and has no other generalized problems. Polyarthritis with minimal systemic problems. The child could be very young, from 1 to 3 years of age, or older, from 8 to 10 years of age. There is no sex predilection in the younger age group, but a definite predilection for girls in the older age group. Five or more joints are involved, which could be any joint in the body. These children have only mild symptoms of low grade fever, malaise, and mild anemia. Polyarthritis with systemic problems. These children acutely with high fever and red swollen joints that mimic infection. The spleen and liver are enlarged, a skin rash is common, and there may be subcutaneous nodules over the elbow and leg. The heart may be enlarged, with inflammation of the pericardium or covering of the heart (called pericarditis).

34. Juvenile Rheumatoid Arthritis Note All links within content go to MayoClinic.com. Diseases and Conditions. juvenile rheumatoid arthritis. From MayoClinic.com Special to CNN.com. Overview. http://www.cnn.com/HEALTH/library/DS/00018.html

International Edition MEMBER SERVICES The Web CNN.com Home Page World U.S. Weather ... Special Reports SERVICES Video E-mail Services CNNtoGO Contact Us SEARCH Web CNN.com In association with: INFORMATION CENTERS: Pick a category Health Centers Family Health Men's Health Women's Health Children's Health Seniors' Health Working Life Pain Management Condition Centers Immune System Allergy Alzheimer's Arthritis Respiratory System Cancer Endocrine System Digestive System Heart and Blood Infectious Disease Mental Health Note: All links within content go to MayoClinic.com Diseases and Conditions Juvenile rheumatoid arthritis From MayoClinic.com Special to CNN.com Overview Still, JRA can be complicated. The term juvenile rheumatoid arthritis is actually an umbrella term for a group of conditions. The conditions are classified according to the number of joints affected, the signs and symptoms, and the results of blood tests. The main categories of JRA are: Pauciarticular JRA. Polyarticular JRA. Systemic JRA. Also known as Still's disease, systemic JRA affects many areas of the body, including joints and internal organs. This is the least common form of JRA. Treatment focuses on ongoing physical activity to maintain full joint movement and strength.

35. AllRefer Health - Juvenile Rheumatoid Arthritis (JRA, Juvenile Chronic Polyarthr juvenile rheumatoid arthritis (JRA, Juvenile Chronic Polyarthritis, Still s Disease) information center covers causes, prevention, symptoms, diagnosis http://health.allrefer.com/health/juvenile-rheumatoid-arthritis-info.html

AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia You are here : AllRefer.com Health Juvenile Rheumatoid Arthritis Juvenile Rheumatoid Arthritis Definition Prevention Treatment Expectations or Prognosis ... Go To Main Page Alternate Names : JRA, Juvenile Chronic Polyarthritis, Still's Disease Definition Juvenile Rheumatoid Arthritis is a chronic, inflammatory disease resulting in joint pain and inflammation. It may result in joint damage. It usually occurs before age 16. Juvenile Rheumatoid Arthritis (JRA) is a chronic inflammatory arthritis in children. It occurs in between 50-100 per 100,000 children in the United States. JRA is a general term for the most common types of arthritis in children. It is divided in to several categories: Systemic JRA: This form, which occurs in about 10% of cases, involves joint pain and swelling as well as fevers and rash. It is similar to

36. AllRefer Health - Juvenile Rheumatoid Arthritis Diagnosis & Tests (JRA, Juvenile juvenile rheumatoid arthritis (JRA, Juvenile Chronic Polyarthritis, Still s Disease) information center covers Diagnosis Tests. juvenile rheumatoid arthritis. http://health.allrefer.com/health/juvenile-rheumatoid-arthritis-diagnosis-tests.

AllRefer Channels :: Yellow Pages Reference Health Home ... Contact Us Quick Jump ADD/ADHD Allergies Alzheimer's Disease Arthritis Asthma Back Pain Breast Cancer Cancer Colon Cancer Depression Diabetes Gallbladder Disease Heart Attack Hepatitis High Cholesterol HIV/AIDS Hypertension Lung Cancer Menopause Migraines/Headaches Osteoporosis Pneumonia Prostate Cancer SARS Stroke Urinary Tract Infection 1600+ More Conditions Alternative Medicine Health News Symptoms Guide Special Topics ... Medical Encyclopedia You are here : AllRefer.com Health Juvenile Rheumatoid Arthritis Juvenile Rheumatoid Arthritis Definition Prevention Treatment Expectations or Prognosis ... Go To Main Page Alternate Names : JRA, Juvenile Chronic Polyarthritis, Still's Disease The physical examination shows swollen, warm, and tender joints that hurt to move. The child may have a rash. Other signs include an enlarged liver enlarged spleen , or swollen lymph nodes Blood tests may include: CBC ESR (sedimentation rate) ANA RA factor HLA antigens for HLA B27 The doctor may need to tap a joint. This means that they will put a small needle into a joint that is swollen. This can help to find the cause of the arthritis. By removing fluid, the joint may feel better, too. Sometimes, the doctor will inject steroids into the joint to help decrease the swelling. Other tests: X-ray of a joint X-ray of the chest ECG Eye exam by an ophthomologist Previous Top Next Jump to another section Definition Juvenile Rheumatoid Arthritis Prevention Juvenile Rheumatoid Arthritis Treatment Juvenile Rheumatoid Arthritis Prognosis ... Calling Your Health Care Provider Topics that might be of interest to you

37. EMedicine Health - Juvenile Rheumatoid Arthritis Overview juvenile rheumatoid arthritis, Overview, juvenile rheumatoid arthritis (JRA), or juvenile arthritis, is not a single disease, but a group of diseases. http://www.emedicinehealth.com/articles/34647-1.asp

Search June 2, 2004 Registration Healthcare Professionals High cholesterol can affect children. Is your child at risk? About 1 million people in the United States have Crohn disease. What are treatment options? Is there a connection between IBD and Crohn Disease? About one third of those with diabetes do not know they have it. Are you one? Two million or more Americans have schizophrenia. Is someone you love affected? One third of those with asthma are children. What are the symptoms and triggers? Asthma Cholesterol Crohn Disease Diabetes ... Mental Health You are in: Arthritis Juvenile Rheumatoid Arthritis Overview The inflammation in the joints causes pain, stiffness, and swelling as well as many other symptoms. The inflammation often affects other organs and systems of the body as well. If the inflammation is not slowed down or stopped, it eventually destroys the affected joints and other tissues. Juvenile rheumatoid arthritis (JRA), or juvenile arthritis, is not a single disease, but a group of diseases. What they all have in common is chronic joint inflammation. Besides this common feature, these diseases are very different in their symptoms, their treatments, and their outcomes. Pauciarticular disease affects only a few joints, fewer than 5. The large joints, such as the shoulder, elbow, hip, and knee, are most likely to be affected. This type is most common in children younger than 8 years. Children who develop this disease have a 20-30% chance of developing inflammatory eye problems and need frequent eye examinations. Children who develop this disease when older than 8 years have a higher-than-normal risk of developing an adult form of arthritis. About 50% of all children with JRA have this type.

38. HON Mother & Child Glossary, Inflammatory Musculoskeletal Disorders: Rheumatoid juvenile rheumatoid arthritis (JRA), also called Idiopathic Arthritis, is the most common type of juvenile arthritis. juvenile rheumatoid arthritis, http://www.hon.ch/Dossier/MotherChild/child_musculoskeletal/muscoskel_arthritis.

Introduction Reproduction Pregnancy During Pregnancy ... Glossary A-Z Childhood Illness Bacteria Virus Cancer Gastrointestinal ... Mental Health Inflammatory Musculoskeletal Disorders: Rheumatoid Arthritis Description Arthritis, Juvenile Rheumatoid : Rheumatoid arthritis of children occurring in three major subtypes defined by the symptoms present during the first six months following onset: systemic-onset (Still's Disease, Juvenile-Onset) polyarticular-onset, and pauciarticular-onset. Adult-onset cases of Still's disease (STILL'S DISEASE, ADULT-ONSET) are also known. Only one subtype of juvenile rheumatoid arthritis (polyarticular-onset, rheumatoid factor-positive) clinically resembles adult rheumatoid arthritis and is considered its childhood equivalent. [1] Tumor Necrosis Factor : Serum glycoprotein produced by activated macrophages and other mammalian mononuclear leukocytes which has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. It mimics the action of endotoxin but differs from it. It has a molecular weight of less than 70,000 kDa. [1] Other HON resources From MedHunt (websites) Juvenile Rheumatoid Arthritis From HONselect Arthritis, Juvenile Rheumatoid

39. Juvenile Rheumatoid Arthritis -- Topic Overview juvenile rheumatoid arthritis Topic Overview Juvenile rheumatoid There are three types of juvenile rheumatoid arthritis. Each type http://my.webmd.com/hw/rheumatoid_arthritis/hw104393.asp

var guid_source = ""; var guid_source_id = ""; //unused var encodedurl = ""; WebMD Today Home WebMD News Center Member Services WebMD University My WebMD Find a Physician Medical Info Check Symptoms Medical Library Quizzes, Calculators Clinical Trials ... Women, Men, Lifestyle Who We Are About WebMD Site Map Health Topics Symptoms ... Credits Juvenile Rheumatoid Arthritis Topic Overview Juvenile rheumatoid arthritis (JRA) is a disease that affects about 1 in 1,000 children aged 16 and younger, resulting in inflamed, swollen joints that are often stiff and painful. The cause of this disease is considered to be autoimmune in nature but is otherwise poorly understood. Unlike adults with rheumatoid arthritis , most children with JRA do not have long-term disease and disability, and go on to lead healthy adult lives. To reflect this, an increasing number of international experts are now referring to JRA as juvenile idiopathic arthritis (JIA); idiopathic means "of unknown cause." As the international terminology transitions into use, you may hear different terms used to describe each type of childhood arthritis. For clarification of the new international "juvenile idiopathic arthritis" classification, as compared with the American "juvenile rheumatoid arthritis" and the European "juvenile chronic arthritis," see classification There are three types of juvenile rheumatoid arthritis. Each type is based on the number of joints affected during the first 6 months:

40. Juvenile Rheumatoid Arthritis (JRA) – From The Cleveland Clinic juvenile rheumatoid arthritis (JRA). juvenile rheumatoid arthritis (JRA) is the most common type of arthritis affecting children. http://my.webmd.com/content/article/78/95639.htm

WebMD Today Home WebMD News Center Member Services WebMD University My WebMD Find a Physician Medical Info Check Symptoms Medical Library Quizzes, Calculators Clinical Trials ... Women, Men, Lifestyle Who We Are About WebMD Site Map You are in Choose a Topic All Conditions ADD/ADHD Allergies Alzheimer's Arthritis Asthma Back Pain Breast Cancer Cancer Dental Depression Diabetes Eye Health Heart Disease Hepatitis HIV/AIDS Hypertension Men's Conditions Mental Health Migraines/Headaches Multiple Sclerosis Osteoporosis Parkinson's Sexual Conditions Stroke Weight Control Women's Conditions WebMD Medical Reference in collaboration with Juvenile Rheumatoid Arthritis (JRA) Get the Facts Types of Arthritis Conditions Related to Arthritis Overuse Injuries ... Day-to-Day To the Arthritis Center Juvenile rheumatoid arthritis (JRA) is the most common type of arthritis affecting children. Rheumatoid arthritis is a chronic (long-lasting) disease that can affect joints in any part of the body. In this disease, the immune system mistakenly targets the tissue that lines the inside of the joint, called the synovium. The synovium responds by making excess fluid (synovial fluid), which leads to swelling, pain and stiffness. The inflammation can then spread to the surrounding tissues, eventually damaging cartilage and bone. Other areas of the body including the eyes, kidneys, lungs and heart also may be affected by the inflammation. Without treatment, JRA can interfere with a child's normal growth and development. There are three main subtypes of JRA, which are based on symptoms and the number of joints involved.

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