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         Isaacs Syndrome:     more detail
  1. Overcoming Metabolic Syndrome by Scott Isaacs, Fred Vagnini, 2005-11-01
  2. Modern Management of Premenstrual Syndrome by Samuel Smith, 1993-04
  3. Your Daughter Has Been Diagnosed With Rett Syndrome by Kim Isaac Greenblatt, 2006-01-01
  4. Diseases of the Salivary Glands: Including Dry Mouth and Sjogren's Syndrome Diagnosis and Treatment by Isaäc van der Waal, 1997-01-15
  5. The Burning Mouth Syndrome by Isaac Van Der Waal, 1990-06
  6. Emergency department response to SARS, Taiwan.(RESEARCH): An article from: Emerging Infectious Diseases by Wei-Kung Chen, Hong-Dar Isaac Wu, et all 2005-07-01

41. »»Reviews For Isaacs Syndrome««
Book reviews for isaacs syndrome sorted by average review score We resorry, but we do not currently have any results listed for this topic.
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42. Mioti: Diseases + Conditions
Diseases + Conditions isaacs syndrome. Search Mioti
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43. PillSupplier.com - Conditions And Diseases/Neurological Disorders/Muscle Disease
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44. Gimenei >> Health >> Conditions_and_Diseases >> Rare_Disorders
Suppurativa; Homocystinuria; Horner Syndrome; Huntington s; Hydrocephalus;Incontinentia Pigmenti; isaacs syndrome; Jacobsen Syndrome; Joubert
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47. Continuous Muscle Fiber Activity ISAACS, Journal Of Neurology, Neurosurgery And
DL, SatyaMurti, S., Davis, L. and Drachman, DB, isaacs syndrome with laryngeal involvementan unusual presentation of myokymia, Neurology, 29 1612-5, 1979.
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Continuous Muscle Fiber Activity Isaacs Journal of Neurology, Neurosurgery and Psychiatry describes the syndrome of continuous muscle fiber activity in two patients, marked by progressive muscle stiffness increased by voluntary muscle contractions and accompanied by fasciculation and weakness. Electromyography recorded a state of constant rapid dysrhythmic discharge of independent muscle fibers. The author defined the state as myotonic afterdischarge and likened it to post-tetanic afterdischarge. Neither patient showed response to numerous medications including quinidine, procainamide, cortisone, and atropine. Treatment with PHT (100 mg q.i.d.) resulted in dramatic improvement in symptoms and electromyographic changes both at rest and on voluntary effort. In a five-year follow-up, the author reported that both patients were still well and had lost their abnormal stiffness. He noted that on the occasions when PHT had been stopped, the symptoms returned.

48. New Page 1
isaacs syndrome assoicated to Health Just The Best Results from the LinkspiderOrganization. Click here for isaacs syndrome assoicated to Health Websites.
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49. Www.nlm.nih.gov/cgi/mesh/2K/MB_cgi?term=Isaacs+Syndrome
NodeWorks Muscle Diseases isaacs syndromein entire NodeWorks Directory.
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50. Health Conditions And Diseases Rare Disorders
Suppurativa@ 11 Homocystinuria@ 4 Horner Syndrome@ 4 Huntington s@ 28 Hydrocephalus@55 Incontinentia Pigmenti@ 7 isaacs syndrome@ 3 Jacobsen
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51. Isaacs Syndrome.
isaacs syndrome. Brown TJ. Although syndrome. The purpose of this paperis to examine pertinent clinical findings about isaacs syndrome.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=DocSum

52. MeSH-D Terms Associated To MeSH-C Term Isaacs Syndrome
MeSHD terms associated to MeSH-C term isaacs syndrome, G2D Home. Thenumber indicates the strength of the association of the corresponding
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53. I-une.com: Muscle Diseases > Isaacs Syndrome
isaacs syndrome. Baylor Neurology Case of the Month A summary and general discussionabout Isaacs syndrome. www.bcm.tmc.edu/neurol/challeng/pat2/summary.html.
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A summary and general discussion about Isaacs' syndrome.
www.bcm.tmc.edu/neurol/challeng/pat2/summary.html Readers Digest Health
A description of Isaacs' syndrome, its alternate names and resources.
www.readersdigesthealth.com/kbase/nord/nord758.htm NORD: Isaacs' Syndrome
A general discussion, the synonyms and further resources.
www.rarediseases.org/search/rdbdetail_abstract.html?disname=Isaacs%27%20Syndrome Search: Isaacs+Syndrome Books Modern Management of Premenstrual Syndrome by Isaac M.D. Schiff, Samuel Smith ( - April, 1993) Our Price: Used Price: Diseases of the Salivary Glands: Including Dry Mouth and Sjogren's Syndrome Diagnosis and Treatment by Isaac Van Der Waal, Leo M. Sreebny, Isaac Van Der Waal, Issac Van Der Waal ( Springer Verlag - 15 January, 1997) Our Price: The Burning Mouth Syndrome by Isaac Van Der Waal ( Mosby - June, 1990)

54. ¹B°Ê»Ùê¾Ç²Õ
A case of isaacs syndrome successfully treated with phenytoin. J FormosMed Assoc 1993;9210101012. 03. Isaacs’ syndrome report of a case.
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¹B°Ê»Ùª¾Ç²Õ ³¯¬X½å ¦^¤W¤@­¶ ½s¸¹ Rou-Shayn Chen , Chin-Chang Huang, Cheng-Chun Lee, Yau-Yau Wai, Mou-Song Hsi, Cheng-Yoong Pang, Yau-Huei Wei. Overlapping syndrome of MERRF and MELAS: molecular and neuroradiological studies. Acta Neurol Scand 1993;87:494-498. Yeu-Jhy Chang, Chia-Lun Wu, Rou-Shayn Chen , Chin-Song Lu. A case of Isaacs syndrome successfully treated with phenytoin. J Formos Med Assoc 1993;92:1010-1012. Woan Fang, Chin-Chang Huang, Nai-Shin Chu, Cheng-Chun Lee, Rou-Shayn Chen , Cheng-Yoong Pang, Kwang-Dar Shih, Yau-Huei Wei. Myoclonic epilepsy with ragged-red fibers (MERRF) syndrome: report of a Chinese family with mitochondrial DNA point mutation in tRNA Lys gene. Muscle Nerve 1994;17:52-57. Chin-Chang Huang, R-S Chen , C-M Chen, H-S Wang, C-C Lee, C-Y Pang, H-S Hsu, H-C Lee, Y-H Wei. MELAS syndrome with mitochondrial tRNA Leu(UUR) gene mutation in a Chinese family. J Neurol Neurosury Pschiatry 1994;57:586-589. Chin-Song Lu

55. Any Search Info - Directory: Health Conditions And Diseases Neurological Disorde
Baylor Neurology Case of the Month A summary and general discussion about isaacs syndrome. url www.bcm.tmc.edu/neurol/challeng/pat2/summary.html.
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56. Wauu.DE: Health: Conditions And Diseases: Neurological Disorders: Muscle Disease
Wauu.DE Health Conditions and Diseases NeurologicalDisorders Muscle Diseases isaacs syndrome.
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57. Neurology -- Abstracts: Vernino Et Al. 53 (6): 1233
Autoantibodies specific for 3 neuronal AChRs or voltagegated potassium channelshave been reported in patients with isaacs syndrome, an acquired disorder of
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Myasthenia, thymoma, presynaptic antibodies, and a continuum of neuromuscular hyperexcitability
Steven Vernino, MD, PhD Raymond G. Auger, MD Alison M. Emslie-Smith, MD, PhD C. Michel Harper, MD and Vanda A. Lennon, MD, PhD From the Departments of Neurology (Drs. Vernino, Auger, Emslie-Smith, Harper, and Lennon), Immunology (Dr. Lennon), and Laboratory Medicine and Pathology (Dr. Lennon), Mayo Clinic and Mayo Foundation, Rochester, MN. Address correspondence and reprint requests to Dr. Steven Vernino, Mayo Clinic, Department of Neurology, 200 First Street SW, Rochester, MN 55905. BACKGROUND: Autoantibodies specific for the nicotinic acetylcholine receptor (AChR) of skeletal muscle impair neuromuscular transmission in myasthenia gravis (MG). Autoantibodies specific for

58. Health- Conditions And Diseases- Rare Disorders
Horner Syndrome@ (4); Huntington s@ (28); Hydrocephalus@ (55); IncontinentiaPigmenti@ (7); isaacs syndrome@ (3); Jacobsen Syndrome (2
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  • Fibrous Dysplasia Support Online - For those seeking support and information concerning the rare bone diseases: fibrous dysplasia, McCune Albright Syndrome and Cherubism.

59. Excite Italia - Directory - Isaacs Syndrome
DIRECTORY. Directory Health Conditions_and_Diseases Neurological_Disorders Muscle_Diseases isaacs syndrome. 3 siti nella categoria isaacs syndrome.
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Tempolibero Cinema Programmi TV Oroscopo Arte ... Eros Viaggi Mappe Paesi Hotel Agriturismo ... Aereo e Treni Relazioni Annunci personali Chat Newsgroup 3 siti nella categoria Isaacs Syndrome Baylor Neurology Case of the Month A summary and general discussion about Isaacs' syndrome. http://www.bcm.tmc.edu/neurol/challeng/pat2/summary.html NORD A general discussion, the synonyms and further resources for Isaacs' syndrome. http://www.stepstn.com/cgi-win/nord.exe?proc=GetDocument Readers Digest Health A description of Isaacs' syndrome, its alternate names and resources. http://www.readersdigesthealth.com/kbase/nord/nord758.htm Vedi anche Top: Health: Conditions and Diseases: Musculoskeletal Disorders Top: Health: Conditions and Diseases: Neurological Disorders: Peripheral Nervous System Top: Health: Conditions and Diseases: Rare Disorders Suggerisci un sito ... Diventa un editore makeAD("http://ad.tiscali.com","/SITE=IT.EX.EXCITE/AREA=SEARCH.HOME/POS=R1/LANG=IT/AAMSZ=144x120",144,120)

60. Baylor Neurology Case Of The Month
Diagnosis 1) isaacs syndrome 2) Syncope The patient was then dischargedand was to be followed in clinic. A Review of isaacs syndrome.
http://www.bcm.tmc.edu/neurol/challeng/pat2/summary.html
Summary and Discussion Amit Verma, M.B.B.S.
Chief Resident, Department of Neurology Diagnosis:
The patient was admitted to the hospital and received 6 courses of plasma exchange. He was subsequently started on oral prednisone and cyclophosphamide and during his hospital stay noticed a marked improvement in the myokymia and muscle strength. The myotonia improved as well. The patient was then discharged and was to be followed in clinic.
A Review of Isaacs' Syndrome
Epidemiology
The condition is extremely rare and has therefore never been studied in a controlled fashion. A recent review of all reported cases by Jamieson and Katiriji in 1994 suggests an equal incidence in both sexes. The disease appears to present earlier in life with most patients being less than 40 years of age at the time of symptom onset. A study of 3 families by Ashizawa et al in 1983 suggested a dominant mode of inheritance in the familial form of the disease.
Etiology and Pathogenesis
The etiology of the disease remains unclear. Isaacs in 1961 was the first person to localize the disorder to the peripheral nerves. Pharmacological localization of the generator of the myokymia seems to confirm the initial observations of Isaacs. More exact localization has been less fruitful. The electrical activity appears to originate from multiple sites in the axon. There is some evidence to suggest the role of autoimmunity and, specifically, antibodies against the potassium channel in motor nerve terminals. The potential importance of circulating antibodies is supported by the fact that plasma exchange is effective in treatment of some patients with this disease. A recent case has been reported in which a patient met criteria for both Isaacs' syndrome and CIDP, another potential autoimmune disease.

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