61. Urology - Immunoglobulin A (IgA) Nephropathy Immunoglobulin A (IgA) Nephropathy. What is iga nephropathy? What causes iga nephropathy?The IgA protein is a normal part of the body s immune system. http://uuhsc.utah.edu/healthinfo/adult/urology/iganeph.htm

Immunoglobulin A (IgA) Nephropathy What is IgA nephropathy? IgA nephropathy is a chronic kidney disease that may progress over a period of 10 to 20 years, and can lead to end-stage renal disease. It is caused by deposits of the protein immunoglobulin A (IgA) inside the glomeruli (filters) within the kidney. These glomeruli normally filter waste and excess water from the blood and send them to the bladder as urine. However, the IgA protein prevents this filtering process. This may lead to the following: blood and protein in the urine swelling in the hands and feet What causes IgA nephropathy? The IgA protein is a normal part of the body's immune system. It is unknown what causes IgA deposits in the glomeruli, however, in more than half of families, IgA nephropathy is inherited by an autosomal dominant gene. Autosomal dominant inheritance means that the gene is located on one of the autosomes (chromosome pairs 1 through 22). This means that males and females are equally affected, and "dominant" means that only one gene is necessary to have the trait. When a parent has a dominant trait, there is a 50 percent chance that any child they have will also inherit the trait. IgA nephropathy is a very heterogeneous condition, which means that the presentation varies greatly between individuals and families. In fact, some persons who inherit the gene may not have any symptoms, but could pass the gene on to the next generation. Many times men are affected more often than women.

62. Ministry Health Care Immunoglobulin A (IgA) Nephropathy. What is iga nephropathy? What causes iga nephropathy?The IgA protein is a normal part of the body s immune system. http://www.ministryhealth.org/display/PPF/DocID/19383/router.aspx

Locations/Maps Print Page Site Map Home Page ... Overview of Urogenital Disorders Immunoglobulin A (IgA) Nephropathy Search Home Page Overview of Urogenital Disorders Analgesic Nephropathy Bladder Cancer ... Hemolytic Uremic Syndrome Immunoglobulin A (IgA) Nephropathy Impotence / Erectile Dysfunction Interstitial Cystitis Kidney Cancer Kidney Stones ... The Ministry Network Immunoglobulin A (IgA) Nephropathy What is IgA nephropathy? IgA nephropathy is a chronic kidney disease that may progress over a period of 10 to 20 years, and can lead to end-stage renal disease. It is caused by deposits of the protein immunoglobulin A (IgA) inside the glomeruli (filters) within the kidney. These glomeruli normally filter waste and excess water from the blood and send them to the bladder as urine. However, the IgA protein prevents this filtering process. This may lead to the following: blood and protein in the urine swelling in the hands and feet What causes IgA nephropathy? The IgA protein is a normal part of the body's immune system. It is unknown what causes IgA deposits in the glomeruli, however, in more than half of families, IgA nephropathy is inherited by an autosomal dominant gene. Autosomal dominant inheritance means that the gene is located on one of the autosomes (chromosome pairs 1 through 22). This means that males and females are equally affected, and "dominant" means that only one gene is necessary to have the trait. When a parent has a dominant trait, there is a 50 percent chance that any child they have will also inherit the trait.

63. IgA Nephropathy Pathogenesis of iga nephropathy. The pathogenesis of iga nephropathy, the mostcommon form of glomerulonephritis in the world, is still largely unknown. http://www.lifespan.org/nephrology/research/patho.html

Pathogenesis of IgA Nephropathy Abdalla Rifai, Ph.D The pathogenesis of IgA nephropathy, the most common form of glomerulonephritis in the world, is still largely unknown. Utilizing an experimental model of IgA immune complex-mediated nephropathy, our laboratory is focused on elucidating in vivo the cellular and molecular mechanisms that are associated with glomerular IgA immune deposits. Identification of the early molecular events induced by glomerular IgA deposition includes establishing a profile of proinflammatory cytokines, chemokines and growth factors that initiate renal tissue injury. In addition, differential expression of extracellular matrix genes involved in the progressive stages of renal fibrosis is being characterized in a chronic model of this disease. This approach promises to provide an opportunity to develop rational therapies for IgA nephropathy. Home Search News Find a Physician ... Site Map Web site design by Lifespan By using this website, you accept the terms of our user agreement . Please read it.

64. Disease - IgA Nephropathy (Berger´s Disease) - Hartford, Connecticut , Saint Fr Disease iga nephropathy (Berger´s disease) - courtesy of Saint Francis Careof Hartford, Connecticut, contemporary medicine with major clinical http://www.saintfranciscare.com/12560.cfm

@import url(main.css); About Us Health Information Adam Article Manager CareMail Signup ... Ways To Help Adam Article Manager Back Back to main Health Information page Male urinary system Definition: IgA nephropathy is a kidney disorder characterized by blood in the urine ; caused by inflammation of the internal kidney structures and deposits of IgA antibodies in the kidney mesangial tissue. Alternative Names: Causes And Risk: renal glomeruli occurs, and there are IgA (a type of antibody ) deposits in the kidney. The disorder can appear as acute , rapidly progressive, or chronic glomerulonephritis ; or as visible or microscopic hematuria blood in the urine IgA nephropathy usually is discovered after one or more episodes of dark or bloody urine in a person with no other symptoms of kidney disorder. Bloody urine may begin during or soon after a respiratory infection. Acute nephritic syndrome or nephrotic syndrome (groups of symptoms associated with decreased kidney functioning) may result. Risk factors include having a personal or family history of IgA nephropathy or Henoch Schonlein purpura (a form of vasculitis IgA nephropathy can occur in persons of all ages, but most often affects males in their teens to late 30s.

65. IgA Nephropathy,Berger's Disease,Idiopathic Renal Hematuria,Mesangial IGA Nephro iga nephropathy,Berger s Disease,Idiopathic Renal Hematuria,Mesangial iga nephropathy,IgANephropathy,Berger s Disease,Idiopathic Renal Hematuria,Mesangial IGA http://www.icomm.ca/geneinfo/iga.htm

IgA Nephropathy,Berger's Disease,Idiopathic Renal Hematuria,Mesangial IGA Nephropathy,IgA Nephropathy,Berger's Disease,Idiopathic Renal Hematuria,Mesangial IGA Nephropathy For Information on Workshops and Seminars for Special Needs Children click here The GAPS INDEX to Information on the Internet about Genetic Disorders and Birth Defects Genetic Information and Patient Services, Inc. (GAPS) HOME DISORDERS GLOSSARY IgA Neuropathy (as defined by the National Organization for Rare Disorders also known as: Berger's Disease Idiopathic Renal Hematuria Mesangial IGA Nephropathy IgA Nephropathy is a kidney disorder occuring during childhood and young adulthood. It usually follows a viral infection of the upper respiratory or gastrointestinal tracts. The major symptom is the passing of blood in the urine (hematuria). There may be associated pain in the loin area. Find more information on the Internet with Select name of the disorder IgA Nephropathy Berger's Disease Idiopathic Renal Hematuria Mesangial IGA Nephropathy SUPPORT GROUPS and information sites: IgA Nephropathy Support Network 400 B Main Rd Gill MA 01376 USA e-mail: N/A Home Page: N/A National Kidney Foundation 30 East 33rd Street New York NY 10016 USA e-mail: N/A Home Page: http://www.kidney.org

66. Health Library - iga nephropathy. Synonyms Disorder Subdivisions General Discussion Resources iga nephropathyis a kidney disorder occuring during childhood and young adulthood. http://health_info.nmh.org/Library/HealthGuide/IllnessConditions/topic.asp?hwid=

67. IgA Nephropathy Vanderbilt Medical Center An article about iga nephropathy. iga nephropathy- A personal story of Darryl who had this disease. http://www.thenewhealthfind.com/Health/ConditionsandDiseases/UrologicalDisorders

Directory Home Health Conditions and Diseases Urological Disorders ... Glomerular : IgA Nephropathy (11) Vanderbilt Medical Center - An article about IgA nephropathy. American Autoimmune Related Diseases Association - A brief description of IgA nephropathy and who usually gets it. IgA Nephropathy - A personal story of Darryl who had this disease. From the beginning, to the diagnosis, the kidney transplant and the update. Methodist Health Care System - A description of IgA nephropathy along with a look at the causes, symptoms and treatment. IgA Nephropathy - From NIDDK a description of this disease along with some further resources. Outlines in Clinical Medicine - A detailed look at IgA nephropathy, the occurrences and symptoms, pathology and treatment. Virtual Hospital - An article written by Donna J. Lager, M.D. about IgA nephropathy. Western Queens Dialysis - Causes of IgA nephropathy, written by Ari Kostadaras, MD. Looks at the pathology, presenting symptoms, diagnosis and etiology. Yahoo Groups - Information about an IgA Nephropathy patient support group with email list, news and current medical and evidence-based information. Adam. com: An Overview

68. IgA Nephropathy (Berger S Disease)- Medcohealth.com iga nephropathy is a kidney disorder characterized by blood in the urine; causedby inflammation of the internal kidney structures and deposits of IgA http://www.medcohealth.com/medco/consumer/ehealth/ehsarticle.jsp?topicID=HE:Dise

69. Alveolar Hemorrhage In IgA Nephropathy Treated With Plasmapheresis Alveolar Hemorrhage in iga nephropathy Treated With Plasmapheresis. Findingswere consistent with HenochSchönlein syndrome or iga nephropathy. http://www.sma.org/smj/97feb16.htm

Alveolar Hemorrhage in IgA Nephropathy Treated With Plasmapheresis BEKELE AFESSA, MD, RANDY G. COWART, MD, and STEVEN M. KOENIG, MD, Belleville, Ill ABSTRACT: A 66-year-old man had diffuse alveolar hemorrhage and rapidly progressive glomerulonephritis due to IgA nephropathy. The diffuse alveolar hemorrhage resolved after high-dose corticosteroid therapy, and renal function improved after plasmapheresis. This response suggests an adjunctive role for plasmapheresis in the treatment of patients presenting this rare clinical picture. CASE REPORT Laboratory tests were done 1 month before and on the day of admission (Table). Erythrocyte sedimentation rate was normal. Cultures of blood, urine, and sputum were negative for organisms. Arterial blood gas measurements showed pH 7.38, PaO2 63.5 mm Hg, and PaCO2 38.3 mm Hg. Urinalysis showed pH 5 and protein 500 mg/dL; red blood cells too numerous to count; 20 to 25 white blood cells per high-power field; and many granular, few hyaline, and occasional red blood cell casts. Chest roentgenography revealed diffuse, bilateral, symmetrical alveolar infiltrates. Echocardiography and renal ultrasonography were unremarkable. Left maxillary sinus wall thickening was seen on sinus roentgenograms. On pulmonary function testing, spirometry and lung volumes were normal but carbon monoxide diffusion capacity (DLCO) was 132% of the predicted value. DISCUSSION References 1. Travis WD, Colby TV, Lombard C, et al: A clinicopathologic study of 34 cases of diffuse pulmonary hemorrhage with lung biopsy confirmation.

70. What Is IgA Nephropathy? What is iga nephropathy? by Anonymous Sender anonymous@EMAIL PROTECTED Apr6, 2004 at 0328 PM Causes The causes of iga nephropathy are not known. http://www.talkaboutsupport.com/group/alt.support.kidney-failure/messages/22275.

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71. What Is IgA Nephropathy What is iga nephropathy by IgAN nomailfacility@EMAIL PROTECTED Apr 9,2004 at 0751 PM Causes The causes of iga nephropathy are not known. http://www.talkaboutsupport.com/group/alt.support.kidney-failure/messages/22303.

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72. Kidney Transplantation For Patients With IgA Nephropathy Kidney transplantation for patients with iga nephropathy. Questionwas submitted by Giovanni Mauro, MD on 11/30/95. Question A http://www.transweb.org/qa/askarchive/answers9511/transplantationinIGAGNFR.html

Kidney transplantation for patients with IgA nephropathy Question was submitted by: Giovanni Mauro, MD on 11/30/95. Question: A good friend of mine has been diagnosed of Berger's IG A glomerulonephritis when she was 8. Her conditions worsened at the end of 1994. Now she has chronic uremia, and she is under daily peritoneal dialysis from March 1995. The doctors said that there are small possibilities of transplantation because the disease can affect the new kidney too. A Medline search showed us that in this disease the survival of the transplanted kidney can reach 66%. We would like to have an expert opinion about this case. She is 32, 44 kg, high blood pressure. We can give any further needed infos, lab findings, etc. Thank you very much for your assistance. Answer: Physicians in the United States do not hesitate to transplant individuals with IgA Nephropathy. The incidence of clinically relevant recurrence is certainly accepted as less than 10%. Alan Leichtman, MD (transplant nephrologist), University of Michigan List of Questions and Answers TransWeb

73. Genitourinary Disorders: Kidney: IgA Nephropathy Genitourinary Disorders Kidney iga nephropathy. iga nephropathy also known asberger s disease, a look at what it is, causes, incidence and risk factors. http://www.puredirectory.com/Health/Conditions-and-Diseases/Genitourinary-Disord

Genitourinary Disorders: Kidney: IgA Nephropathy Home Health Conditions and Diseases Genitourinary Disorders ... Kidney : IgA Nephropathy google_ad_client = 'pub-3272565765518472';google_ad_width = 336;google_ad_height = 280;google_ad_format = '336x280_as';google_color_border = 'FFFFFF';google_color_bg = 'FFFFFF';google_ad_channel ='7485447737';google_alternate_color = 'FFFFFF';google_color_link = '0000FF';google_color_url = '008000';google_color_text = '000000'; Standard Listings Adam. com: An Overview IgA nephropathy also known as berger's disease, a look at what it is, causes, incidence and risk factors. Australian Kidney Fact Sheet IgA nephropathy, what it is, diagnosis, causes, the course of the disease, follow up and treatment. IgA Nephropathy A personal story of Darryl who had this disease. From the beginning, to the diagnosis, the kidney transplant and the update. IgA Nephropathy From NIDDK a description of this disease along with some further resources. Methodist Health Care System A description of IgA nephropathy along with a look at the causes, symptoms and treatment. Outlines in Clinical Medicine A detailed look at IgA nephropathy, the occurrences and symptoms, pathology and treatment.

74. Research - IgA Nephropathy iga nephropathy Key investigators Prof KN Lai, Dr JCK Leung. iga nephropathyis the most common primary kidney disease that can result in kidney failure. http://www.hku.hk/medicine/divisions/renal/research/iga.htm

Department of Medicine Nephrology Home Research IgA Nephropathy Proteinuria and Renal Tubular Epithelial Cell Function Aquaporins Lupus Nephritis ... In vivo Actions of Immunosuppressive Drugs IgA Nephropathy [ Key investigators : Prof KN Lai, Dr JCK Leung] IgA nephropathy is the most common primary kidney disease that can result in kidney failure. We are one of the leaders in research into the molecular mechanisms involved in this condition, focusing on interactions between the IgA molecule and kidney cells. Basic and clinical research topics : Abnormality of IgA molecules in IgAN Mechanism of mesangial IgA deposition Pathophysiologic effect of IgA in kidney injury Representative publications Lai KN, Chan LYY, Tang SC, Tsang AWL, Guo H, Tse KC, Yip T, Leung JCK. Characteristics of Polymeric lambda-IgA Binding to Leukocytes in IgA Nephropathy. J Am Soc Nephrol Leung JCK, Tang S, Lam MF, Chan DTM, Lai KN. Charge-dependent binding of polymeric IgA1 to human mesangial cells in IgA nephropathy. Kidney Int Leung JCK, Tsang AWL, Chan DTM, Lai KN. Absence of CD89, polymeric immunoglobulin receptor, and

75. Immunosuppressive Agents For Treating IgA Nephropathy (Cochrane Review) Immunosuppressive agents for treating iga nephropathy (Cochrane Review). Immunosuppressiveagents for treating iga nephropathy (Cochrane Review). http://www.update-software.com/abstracts/AB003965.htm

From The Cochrane Library, Issue 2, 2004 Immunosuppressive agents for treating IgA nephropathy (Cochrane Review) Samuels JA, Strippoli GFM, Craig JC, Schena FP, Molony DA ABSTRACT Order full review View and/or submit comments What's new in this issue Search abstracts ... Browse by Review Group A substantive amendment to this systematic review was last made on 09 June 2003. Cochrane reviews are regularly checked and updated if necessary. Background: IgA nephropathy (IgAN) is a world-wide disease and the cause of end-stage renal failure (ESRF) in 15 to 20% of patients within 10 years and in 30 to 40% of individuals within 20 years from the apparent onset of disease. No specific treatment has yet been established but many approaches have been investigated. Objectives: To assess the benefits and harms of immunosuppressive treatment for IgAN. Search strategy: We searched The Cochrane Renal Group's specialized register (May 2003), Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library, Issue 3, 2002) MEDLINE (1966 - September 2002), EMBASE (1988 - September 2002) and handsearched reference lists of retrieved articles and conference proceedings. Selection criteria: Randomized controlled trials (RCTs) and quasi-RCTs comparing treatment of IgAN with immunosuppressive agents against placebo, no treatment, other immunosuppressive or non-immunosuppressive agents.

76. 4th Glomerulonephritis-Workshop: IgA-Nephropathy, Abstracts W. Schoeppe iga nephropathy epidemiology. (Nieren Hochdruckkrh 1994 (23)538 - 540). T. Risler, N. Braun Clinical course of iga nephropathy. http://www.uni-tuebingen.de/uni/kmp/tusem4_e.htm

Weiter Heim 4th Glomerulonephritis-Workshop: IgA-Nephropathy W. Schoeppe: IgA nephropathy - epidemiology (Nieren Hochdruckkrh 1994 (23) 538 - 540). After Berger's first report on a nosological entity of recurrent hematuria and proteinuria together with mesangial IgA-depositions increasing information exists in the literature to correlate the disease with further etiological, epidemiological and prognostic characteristics. 1.5 to 35 % of patients with renal biopsy show IgA nephropathy reaching peaks in Japan and France compared to low frequencies in Northern America (USA + Canada). Finding of IgA deposits is frequently related to infections of the respiratory tract. Key words: Mesangial IgA deposits - etiological and epidemiological factors. M. Rambausek, A. Schwarzbeck, E. Ritz: Pathophysiology of mesangial IgA glomerulonephritis (Nieren Hochdruckkrh 1994 (23) 541 - 547). In patients with mesangial IgA glomerulonephritis impaired activity of suppressor-inducer T-cells, decreased suppressor T-cell activity and a hyperactivity of T-helper cells is found. This results in increased production of IgA and IgA-immune-complexes. It is suspected that oral tolerance is also disturbed in IgA-nephropathy. The familial occurrence and deviations in allele frequencies of certain HLA-subtypes, complement components and of immunoglobulin genes point to a genetic predisposition for IgA nephropathy. It is presently unknown how IgA immune complexes result in glomerular mesangial damage. Key words: Mesangial IgA glomerulonephritis - Pathophysiology.

77. Immunoglobulin A (IgA) Nephropathy Detailed information on iga nephropathy, including cause, symptoms, diagnosis,and treatment. Immunoglobulin A (IgA) Nephropathy. What is iga nephropathy? http://www.healthsystem.virginia.edu/uvahealth/adult_urology/iganeph.cfm

@import url(/assets/UVAHealth/ssi/css/greystone_advance.css); Blood Disorders Bone Disorders Breast Health Cardiovascular Disease Dermatology Diabetes Digestive Disorders Endocrinology Environmental Medicine Eye Care Glossary Gynecological Health Infectious Diseases Kidney Disease Men's Health Mental Health Nervous System Disorders Non-Trauma Emergency Oral Health Orthopaedics Otolaryngology Pathology Pediatrics, General Health Prostate Health Radiology Respiratory Disorders Skin Cancer Surgical Care Urology Women's Health FIND A DOCTOR MAKE AN APPOINTMENT CALENDAR OF EVENTS CLINICAL TRIALS ... WHY CHOOSE UVA Immunoglobulin A (IgA) Nephropathy What is IgA nephropathy? IgA nephropathy is a chronic kidney disease that may progress over a period of 10 to 20 years, and can lead to end-stage renal disease. It is caused by deposits of the protein immunoglobulin A (IgA) inside the glomeruli (filters) within the kidney. These glomeruli normally filter waste and excess water from the blood and send them to the bladder as urine. However, the IgA protein prevents this filtering process. This may lead to the following: blood and protein in the urine swelling in the hands and feet What causes IgA nephropathy?

78. Health, Conditions And Diseases, Genitourinary Disorders, Kidney: IgA Nephropath Adam. com An Overview iga nephropathy also known as berger s disease,a look at what it is, causes, incidence and risk factors. http://www.combose.com/Health/Conditions_and_Diseases/Genitourinary_Disorders/Ki

Top Health Conditions and Diseases Genitourinary Disorders ... Adam. com: An Overview - IgA nephropathy also known as berger's disease, a look at what it is, causes, incidence and risk factors. Australian Kidney Fact Sheet - IgA nephropathy, what it is, diagnosis, causes, the course of the disease, follow up and treatment. IgA Nephropathy - From NIDDK a description of this disease along with some further resources. Methodist Health Care System - A description of IgA nephropathy along with a look at the causes, symptoms and treatment. Outlines in Clinical Medicine - A detailed look at IgA nephropathy, the occurrences and symptoms, pathology and treatment. Vanderbilt Medical Center - An article about IgA nephropathy. Virtual Hospital - An article written by Donna J. Lager, M.D. about IgA nephropathy. Western Queens Dialysis - Causes of IgA nephropathy, written by Ari Kostadaras, MD. Looks at the pathology, presenting symptoms, diagnosis and etiology. Yahoo Groups - Information about an IgA Nephropathy patient support group with email list, news and current medical and evidence-based information. A kidney disorder characterized by blood in the urine; caused by inflammation of the internal kidney structures and deposits of IgA antibodies in the kidney mesangial tissue.

79. :: Ez2Find :: IgA Nephropathy Guide iga nephropathy, Global Metasearch Any Language Guides, iga nephropathy.ez2Find Home Directory Health http://ez2find.com/cgi-bin/directory/meta/search.pl/Health/Conditions_and_Diseas

Guide : IgA Nephropathy Global Metasearch Any Language English Afrikaans Arabic Bahasa Melayu Belarusian Bulgarian Catala Chinese Simplified Chinese Traditional Cymraeg Czech Dansk Deutsch Eesti Espanol Euskara Faroese Francais Frysk Galego Greek Hebrew Hrvatski Indonesia Islenska Italiano Japanese Korean Latvian Lietuviu Lingua Latina Magyar Netherlands Norsk Polska Portugues Romana Russian Shqip Slovensko Slovensky Srpski Suomi Svenska Thai Turkce Ukrainian Vietnamese Mode All Words Any Word Phrase Results Timeout Depth Adult Filter Add to Favorites Other Search Web News Newsgroups Images Guides IgA Nephropathy ez2Find Home Directory Health Conditions and Diseases ... Kidney : IgA Nephropathy Web Sites Adam. com: An Overview [Site Info] [Translate] [Open New Window] IgA nephropathy also known as berger's disease, a look at what it is, causes, incidence and risk factors. URL: http://www.nlm.nih.gov/medlineplus/ency/article/000466.htm Australian Kidney Fact Sheet [Site Info] [Translate] [Open New Window] IgA nephropathy, what it is, diagnosis, causes, the course of the disease, follow up and treatment. URL: http://www.kidney.org.au/renal_resources/fact_sheets/iga_nephropathy.asp

80. Thomas Jefferson University Hospital - Immunoglobulin A (IgA) Nephropathy Department of Urology. Immunoglobulin A (IgA) Nephropathy What is IgAnephropathy? iga nephropathy What causes iga nephropathy? The IgA http://www.jeffersonhospital.org/urology/e3front.dll?durki=5284&site=623&return=

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